Rattus norvegicus

112 known processes

Cdk4

cyclin-dependent kinase 4

Cdk4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron death GO:0070997 127 0.624
response to amino acid GO:0043200 75 0.424
cellular response to organonitrogen compound GO:0071417 197 0.416
intracellular signal transduction GO:0035556 314 0.371
positive regulation of cell communication GO:0010647 271 0.363
cellular response to endogenous stimulus GO:0071495 377 0.361
regulation of neuron death GO:1901214 115 0.308
positive regulation of signaling GO:0023056 270 0.275
regulation of intracellular signal transduction GO:1902531 218 0.267
regulation of neuron apoptotic process GO:0043523 83 0.260
carbohydrate metabolic process GO:0005975 130 0.260
response to inorganic substance GO:0010035 377 0.252
response to nutrient GO:0007584 248 0.228
positive regulation of intracellular signal transduction GO:1902533 138 0.221
cellular response to peptide GO:1901653 133 0.219
cellular response to peptide hormone stimulus GO:0071375 120 0.217
response to peptide GO:1901652 292 0.199
cellular component assembly GO:0022607 360 0.198
response to ethanol GO:0045471 162 0.192
apoptotic process GO:0006915 381 0.188
negative regulation of macromolecule metabolic process GO:0010605 260 0.187
response to toxic substance GO:0009636 133 0.185
neuron apoptotic process GO:0051402 88 0.184
response to carbohydrate GO:0009743 183 0.183
single organism carbohydrate metabolic process GO:0044723 118 0.181
response to peptide hormone GO:0043434 278 0.177
response to estradiol GO:0032355 164 0.176
regulation of cellular component organization GO:0051128 368 0.175
cell cycle checkpoint GO:0000075 2 0.175
macromolecular complex assembly GO:0065003 273 0.173
protein complex biogenesis GO:0070271 263 0.169
regulation of rna biosynthetic process GO:2001141 381 0.165
protein complex assembly GO:0006461 263 0.164
negative regulation of protein metabolic process GO:0051248 114 0.162
dna metabolic process GO:0006259 96 0.161
negative regulation of cellular metabolic process GO:0031324 281 0.155
positive regulation of developmental process GO:0051094 283 0.152
aging GO:0007568 241 0.152
response to purine containing compound GO:0014074 126 0.152
regulation of viral transcription GO:0046782 2 0.151
positive regulation of response to stimulus GO:0048584 285 0.150
response to estrogen GO:0043627 232 0.145
positive regulation of cell death GO:0010942 184 0.140
response to insulin GO:0032868 133 0.134
cellular response to hormone stimulus GO:0032870 247 0.130
response to corticosteroid GO:0031960 235 0.125
response to hydrogen peroxide GO:0042542 89 0.123
programmed cell death GO:0012501 392 0.120
reproduction GO:0000003 245 0.116
response to glucocorticoid GO:0051384 223 0.116
cellular protein localization GO:0034613 122 0.116
cellular response to stress GO:0033554 269 0.113
regulation of cell migration GO:0030334 128 0.110
response to nutrient levels GO:0031667 370 0.106
cell cycle GO:0007049 101 0.105
organelle organization GO:0006996 266 0.104
regulation of catalytic activity GO:0050790 304 0.101
cellular component biogenesis GO:0044085 368 0.100
positive regulation of nucleic acid templated transcription GO:1903508 197 0.099
response to acid chemical GO:0001101 222 0.099
macromolecule localization GO:0033036 252 0.095
cellular response to insulin stimulus GO:0032869 81 0.094
cellular macromolecule localization GO:0070727 122 0.094
positive regulation of signal transduction GO:0009967 175 0.092
regulation of transcription dna templated GO:0006355 374 0.091
protein oligomerization GO:0051259 191 0.091
negative regulation of biosynthetic process GO:0009890 168 0.086
negative regulation of cell death GO:0060548 229 0.085
regulation of molecular function GO:0065009 398 0.083
regulation of cell proliferation GO:0042127 359 0.083
response to vitamin GO:0033273 131 0.083
organophosphate metabolic process GO:0019637 370 0.081
response to ketone GO:1901654 182 0.081
cellular response to oxygen containing compound GO:1901701 386 0.079
macromolecular complex subunit organization GO:0043933 339 0.079
multicellular organism reproduction GO:0032504 233 0.079
synaptic transmission GO:0007268 235 0.078
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.077
viral transcription GO:0019083 2 0.077
negative regulation of metabolic process GO:0009892 331 0.076
neuron differentiation GO:0030182 368 0.075
mapk cascade GO:0000165 140 0.074
organic substance catabolic process GO:1901575 316 0.073
positive regulation of cellular component organization GO:0051130 200 0.073
response to decreased oxygen levels GO:0036293 237 0.073
wound healing GO:0042060 122 0.073
regulation of cellular component biogenesis GO:0044087 86 0.073
single organism reproductive process GO:0044702 297 0.072
positive regulation of neuron death GO:1901216 43 0.072
regulation of protein localization GO:0032880 81 0.072
g1 s transition of mitotic cell cycle GO:0000082 12 0.070
positive regulation of transcription dna templated GO:0045893 197 0.070
nucleic acid templated transcription GO:0097659 379 0.068
localization of cell GO:0051674 202 0.067
cell cycle process GO:0022402 57 0.067
response to extracellular stimulus GO:0009991 380 0.066
nucleobase containing small molecule metabolic process GO:0055086 316 0.066
rna metabolic process GO:0016070 406 0.066
positive regulation of cellular component movement GO:0051272 102 0.066
regulation of response to stress GO:0080134 126 0.065
nucleoside phosphate metabolic process GO:0006753 283 0.065
positive regulation of nervous system development GO:0051962 178 0.064
carbohydrate derivative metabolic process GO:1901135 346 0.064
homeostatic process GO:0042592 331 0.064
response to alkaloid GO:0043279 132 0.064
response to cytokine GO:0034097 215 0.063
cellular polysaccharide metabolic process GO:0044264 23 0.061
positive regulation of gene expression GO:0010628 244 0.061
protein transport GO:0015031 132 0.061
regulation of cell cycle GO:0051726 73 0.060
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.060
catabolic process GO:0009056 351 0.060
response to transition metal nanoparticle GO:1990267 122 0.060
response to metal ion GO:0010038 253 0.059
response to reactive oxygen species GO:0000302 120 0.059
transcription from rna polymerase ii promoter GO:0006366 252 0.059
reactive oxygen species metabolic process GO:0072593 37 0.059
reproductive process GO:0022414 372 0.058
negative regulation of cellular biosynthetic process GO:0031327 161 0.058
regulation of apoptotic process GO:0042981 335 0.058
positive regulation of cell proliferation GO:0008284 249 0.058
circadian rhythm GO:0007623 88 0.058
modification dependent protein catabolic process GO:0019941 14 0.057
transcription dna templated GO:0006351 377 0.057
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.057
anatomical structure formation involved in morphogenesis GO:0048646 83 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
rna biosynthetic process GO:0032774 380 0.055
neuron projection morphogenesis GO:0048812 122 0.055
nuclear transport GO:0051169 49 0.054
cellular response to abiotic stimulus GO:0071214 85 0.054
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.054
cellular catabolic process GO:0044248 295 0.054
regulation of cell development GO:0060284 263 0.053
protein complex subunit organization GO:0071822 302 0.052
regulation of cellular protein metabolic process GO:0032268 267 0.050
regulation of multicellular organismal development GO:2000026 376 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.049
protein localization GO:0008104 191 0.049
viral gene expression GO:0019080 2 0.048
positive regulation of apoptotic process GO:0043065 154 0.048
protein phosphorylation GO:0006468 345 0.048
regulation of cell cycle g1 s phase transition GO:1902806 7 0.048
negative regulation of apoptotic process GO:0043066 181 0.048
immune system process GO:0002376 204 0.048
positive regulation of cellular component biogenesis GO:0044089 55 0.047
cellular response to cytokine stimulus GO:0071345 127 0.047
response to hexose GO:0009746 144 0.047
regulation of programmed cell death GO:0043067 341 0.047
cellular homeostasis GO:0019725 252 0.047
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.046
regulation of apoptotic signaling pathway GO:2001233 13 0.046
cell aging GO:0007569 14 0.046
negative regulation of rna metabolic process GO:0051253 123 0.046
cellular response to dna damage stimulus GO:0006974 19 0.045
cellular response to oxidative stress GO:0034599 76 0.045
negative regulation of rna biosynthetic process GO:1902679 118 0.045
energy derivation by oxidation of organic compounds GO:0015980 46 0.045
regulation of kinase activity GO:0043549 117 0.045
cytoplasmic transport GO:0016482 115 0.044
cellular response to nitrogen compound GO:1901699 210 0.044
regulation of phosphorylation GO:0042325 248 0.044
positive regulation of cellular protein metabolic process GO:0032270 167 0.044
negative regulation of cell cycle phase transition GO:1901988 4 0.043
response to growth factor GO:0070848 189 0.043
positive regulation of intracellular protein transport GO:0090316 20 0.043
positive regulation of protein transport GO:0051222 41 0.043
secretion GO:0046903 307 0.042
regulation of anatomical structure size GO:0090066 135 0.042
negative regulation of nucleic acid templated transcription GO:1903507 117 0.042
intracellular transport GO:0046907 185 0.042
regulation of cell growth GO:0001558 85 0.042
negative regulation of response to stimulus GO:0048585 155 0.041
cellular component movement GO:0006928 248 0.041
carbohydrate catabolic process GO:0016052 40 0.041
regulation of neurogenesis GO:0050767 247 0.040
response to glucose GO:0009749 136 0.040
negative regulation of neuron death GO:1901215 69 0.040
positive regulation of catalytic activity GO:0043085 184 0.039
cell type specific apoptotic process GO:0097285 134 0.039
regulation of cell motility GO:2000145 131 0.039
defense response GO:0006952 194 0.039
chromatin assembly or disassembly GO:0006333 1 0.038
regulation of mapk cascade GO:0043408 116 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.038
negative regulation of programmed cell death GO:0043069 183 0.038
negative regulation of cell proliferation GO:0008285 119 0.038
negative regulation of transcription dna templated GO:0045892 116 0.037
dna integrity checkpoint GO:0031570 2 0.037
regulation of secretion by cell GO:1903530 208 0.037
positive regulation of protein modification process GO:0031401 142 0.037
positive regulation of organelle organization GO:0010638 48 0.037
organ regeneration GO:0031100 101 0.036
regulation of cell differentiation GO:0045595 320 0.036
neuron projection development GO:0031175 273 0.036
regulation of cell projection organization GO:0031344 175 0.035
purine nucleoside triphosphate metabolic process GO:0009144 141 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.034
central nervous system development GO:0007417 311 0.034
cellular response to external stimulus GO:0071496 118 0.034
interleukin 1 production GO:0032612 11 0.034
sexual reproduction GO:0019953 148 0.033
amine metabolic process GO:0009308 38 0.033
regulation of secretion GO:0051046 224 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
regulation of cell cycle phase transition GO:1901987 12 0.033
positive regulation of mitochondrion organization GO:0010822 4 0.032
immune response GO:0006955 104 0.032
cellular response to reactive oxygen species GO:0034614 55 0.032
i kappab kinase nf kappab signaling GO:0007249 19 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
positive regulation of apoptotic signaling pathway GO:2001235 6 0.031
response to monosaccharide GO:0034284 159 0.031
tissue development GO:0009888 252 0.031
response to lead ion GO:0010288 33 0.031
regulation of rna metabolic process GO:0051252 391 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
aromatic compound catabolic process GO:0019439 168 0.031
response to endoplasmic reticulum stress GO:0034976 10 0.030
cellular glucan metabolic process GO:0006073 23 0.030
regulation of dna metabolic process GO:0051052 60 0.030
positive regulation of viral transcription GO:0050434 2 0.030
glucan metabolic process GO:0044042 23 0.030
negative regulation of cellular protein metabolic process GO:0032269 106 0.030
gamete generation GO:0007276 124 0.030
growth GO:0040007 165 0.030
carbohydrate derivative biosynthetic process GO:1901137 124 0.030
axis specification GO:0009798 4 0.030
axon development GO:0061564 96 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
response to antibiotic GO:0046677 39 0.029
oxoacid metabolic process GO:0043436 290 0.029
peptidyl amino acid modification GO:0018193 126 0.029
cellular divalent inorganic cation homeostasis GO:0072503 162 0.029
mitotic dna damage checkpoint GO:0044773 1 0.029
neurological system process GO:0050877 219 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
g protein coupled receptor signaling pathway GO:0007186 242 0.029
positive regulation of molecular function GO:0044093 230 0.029
cellular response to growth factor stimulus GO:0071363 162 0.029
intracellular protein transport GO:0006886 79 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.029
carboxylic acid metabolic process GO:0019752 289 0.028
regulation of growth GO:0040008 105 0.028
glial cell differentiation GO:0010001 65 0.028
purine ribonucleotide metabolic process GO:0009150 227 0.028
nucleotide metabolic process GO:0009117 279 0.028
polysaccharide metabolic process GO:0005976 25 0.028
nucleoside triphosphate metabolic process GO:0009141 144 0.028
developmental growth GO:0048589 100 0.028
positive regulation of cell development GO:0010720 176 0.028
regulation of cellular response to stress GO:0080135 49 0.028
positive regulation of cell projection organization GO:0031346 111 0.027
regulation of response to external stimulus GO:0032101 106 0.027
chromatin organization GO:0006325 34 0.027
regulation of cellular localization GO:0060341 263 0.027
regulation of behavior GO:0050795 61 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 8 0.027
regulation of tumor necrosis factor production GO:0032680 13 0.027
regulation of signal transduction GO:0009966 318 0.027
proteolysis GO:0006508 175 0.027
negative regulation of signaling GO:0023057 157 0.027
positive regulation of cell growth GO:0030307 44 0.027
response to other organism GO:0051707 220 0.026
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.026
positive regulation of secretion GO:0051047 140 0.026
protein homooligomerization GO:0051260 91 0.026
response to light stimulus GO:0009416 52 0.026
regulation of organelle organization GO:0033043 80 0.026
protein targeting GO:0006605 61 0.026
regulation of nervous system development GO:0051960 264 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
positive regulation of protein kinase activity GO:0045860 73 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
transmission of nerve impulse GO:0019226 42 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 13 0.026
cellular modified amino acid metabolic process GO:0006575 61 0.025
gland development GO:0048732 155 0.025
response to oxidative stress GO:0006979 186 0.025
rhythmic process GO:0048511 156 0.025
regulation of protein complex assembly GO:0043254 33 0.025
oxidation reduction process GO:0055114 304 0.025
ribose phosphate metabolic process GO:0019693 235 0.024
negative regulation of neuron apoptotic process GO:0043524 45 0.024
lipid metabolic process GO:0006629 283 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
arp2 3 complex mediated actin nucleation GO:0034314 2 0.024
cell part morphogenesis GO:0032990 123 0.024
heterocycle catabolic process GO:0046700 167 0.024
positive regulation of secretion by cell GO:1903532 128 0.024
exocytosis GO:0006887 60 0.024
anion transport GO:0006820 178 0.023
regulation of protein metabolic process GO:0051246 289 0.023
positive regulation of protein metabolic process GO:0051247 178 0.023
apoptotic signaling pathway GO:0097190 27 0.023
cell projection organization GO:0030030 302 0.023
cellular macromolecular complex assembly GO:0034622 58 0.023
negative regulation of signal transduction GO:0009968 83 0.023
single organism biosynthetic process GO:0044711 342 0.023
cell projection morphogenesis GO:0048858 123 0.023
negative regulation of molecular function GO:0044092 133 0.022
sensory organ development GO:0007423 74 0.022
regulation of protein heterodimerization activity GO:0043497 1 0.022
behavior GO:0007610 205 0.022
dna damage checkpoint GO:0000077 2 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
hexose metabolic process GO:0019318 58 0.022
eye morphogenesis GO:0048592 4 0.022
negative regulation of catalytic activity GO:0043086 103 0.022
nucleocytoplasmic transport GO:0006913 48 0.022
chemical homeostasis GO:0048878 292 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
heart morphogenesis GO:0003007 3 0.022
cell motility GO:0048870 202 0.021
cellular amine metabolic process GO:0044106 38 0.021
taxis GO:0042330 67 0.021
regulation of protein modification process GO:0031399 194 0.021
organic acid metabolic process GO:0006082 292 0.021
stress activated protein kinase signaling cascade GO:0031098 37 0.021
spermatogenesis GO:0007283 99 0.021
regulation of proteolysis GO:0030162 66 0.021
positive regulation of protein oligomerization GO:0032461 1 0.021
positive regulation of dna metabolic process GO:0051054 39 0.021
regulation of cytokine production GO:0001817 56 0.021
multicellular organism growth GO:0035264 1 0.021
regulation of transferase activity GO:0051338 123 0.021
positive regulation of locomotion GO:0040017 102 0.021
ion transmembrane transport GO:0034220 365 0.021
cell adhesion GO:0007155 110 0.021
mitotic cell cycle checkpoint GO:0007093 1 0.021
negative regulation of cellular component organization GO:0051129 83 0.020
regulation of cell adhesion GO:0030155 52 0.020
response to oxygen radical GO:0000305 8 0.020
multi organism reproductive process GO:0044703 262 0.020
regulation of exocytosis GO:0017157 37 0.020
cellular amide metabolic process GO:0043603 44 0.020
response to testosterone GO:0033574 55 0.020
negative regulation of stress activated mapk cascade GO:0032873 4 0.020
regulation of establishment of protein localization GO:0070201 69 0.019
nucleotide catabolic process GO:0009166 139 0.019
regulation of cellular component size GO:0032535 51 0.019
response to oxygen levels GO:0070482 265 0.019
neuronal action potential GO:0019228 35 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
cellular chemical homeostasis GO:0055082 247 0.019
positive regulation of growth GO:0045927 55 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
regulation of developmental growth GO:0048638 45 0.019
establishment of protein localization GO:0045184 141 0.019
negative regulation of cell communication GO:0010648 158 0.019
camera type eye development GO:0043010 48 0.018
nucleoside metabolic process GO:0009116 179 0.018
cellular ion homeostasis GO:0006873 184 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
regulation of protein kinase activity GO:0045859 105 0.018
response to mechanical stimulus GO:0009612 134 0.018
axonogenesis GO:0007409 71 0.018
actin filament bundle organization GO:0061572 19 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
muscle cell apoptotic process GO:0010657 30 0.018
somatic stem cell division GO:0048103 2 0.018
protein modification by small protein conjugation or removal GO:0070647 35 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
developmental process involved in reproduction GO:0003006 159 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
single organism intracellular transport GO:1902582 166 0.018
regulation of actin nucleation GO:0051125 2 0.017
biological adhesion GO:0022610 110 0.017
protein localization to organelle GO:0033365 57 0.017
outer mitochondrial membrane organization GO:0007008 1 0.017
bmp signaling pathway GO:0030509 4 0.017
cyclic nucleotide metabolic process GO:0009187 80 0.017
regeneration GO:0031099 163 0.017
epithelium development GO:0060429 96 0.017
organic anion transport GO:0015711 132 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
purine containing compound metabolic process GO:0072521 253 0.017
regulation of peptidase activity GO:0052547 55 0.017
cellular response to lipid GO:0071396 201 0.017
negative regulation of cell cycle g1 s phase transition GO:1902807 2 0.017
muscle cell proliferation GO:0033002 84 0.016
protein polymerization GO:0051258 22 0.016
protein import into nucleus GO:0006606 35 0.016
actin nucleation GO:0045010 2 0.016
regulation of protein serine threonine kinase activity GO:0071900 64 0.016
positive regulation of protein secretion GO:0050714 19 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
organ morphogenesis GO:0009887 75 0.016
cell cycle g1 s phase transition GO:0044843 13 0.016
response to ammonium ion GO:0060359 71 0.016
protein localization to nucleus GO:0034504 39 0.016
response to organophosphorus GO:0046683 102 0.016
positive regulation of multicellular organismal process GO:0051240 387 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
antigen receptor mediated signaling pathway GO:0050851 1 0.016
positive regulation of release of cytochrome c from mitochondria GO:0090200 3 0.016
cytokine production GO:0001816 61 0.016
mitotic cell cycle phase transition GO:0044772 20 0.016
brain development GO:0007420 247 0.016
amide transport GO:0042886 105 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
hair cycle process GO:0022405 2 0.015
regulation of cytokine biosynthetic process GO:0042035 3 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
release of cytochrome c from mitochondria GO:0001836 8 0.015
positive regulation of neuron apoptotic process GO:0043525 33 0.015
male gamete generation GO:0048232 99 0.015
response to cold GO:0009409 29 0.015
regulation of protein polymerization GO:0032271 19 0.015
regulation of endopeptidase activity GO:0052548 51 0.015
cell cycle phase transition GO:0044770 21 0.015
response to camp GO:0051591 91 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
cation homeostasis GO:0055080 195 0.015
response to fatty acid GO:0070542 65 0.015
positive regulation of epithelial cell proliferation GO:0050679 32 0.015
cellular response to superoxide GO:0071451 6 0.015
energy reserve metabolic process GO:0006112 25 0.015
regulation of locomotion GO:0040012 148 0.015
generation of precursor metabolites and energy GO:0006091 62 0.015
positive regulation of cellular catabolic process GO:0031331 71 0.014
glycogen biosynthetic process GO:0005978 15 0.014
ion homeostasis GO:0050801 212 0.014
chromosome organization GO:0051276 36 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
negative regulation of cell cycle GO:0045786 21 0.014
mitotic cell cycle GO:0000278 49 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
anion transmembrane transport GO:0098656 77 0.014
negative regulation of smooth muscle cell proliferation GO:0048662 21 0.014
negative regulation of protein modification process GO:0031400 52 0.014
regulation of cell cycle process GO:0010564 31 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of immune system process GO:0002682 123 0.014
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
positive regulation of kinase activity GO:0033674 77 0.014
multi multicellular organism process GO:0044706 138 0.014
vesicle localization GO:0051648 33 0.014
single organism organelle organization GO:1902589 180 0.013
negative regulation of peptidase activity GO:0010466 38 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
response to radiation GO:0009314 137 0.013
single organism catabolic process GO:0044712 283 0.013
positive regulation of cell motility GO:2000147 97 0.013
ovulation cycle GO:0042698 67 0.013
regulation of cellular component movement GO:0051270 150 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
embryonic axis specification GO:0000578 1 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
neuron development GO:0048666 286 0.013
regulation of epithelial cell proliferation GO:0050678 49 0.013
regulation of hormone levels GO:0010817 187 0.013
sulfur compound metabolic process GO:0006790 70 0.013
glucan biosynthetic process GO:0009250 15 0.013
sensory perception GO:0007600 101 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
regulation of embryonic development GO:0045995 2 0.013
smooth muscle cell migration GO:0014909 36 0.013
circadian regulation of gene expression GO:0032922 3 0.013
glycosaminoglycan biosynthetic process GO:0006024 4 0.013
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.012

Cdk4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.356
intestinal cancer DOID:10155 0 0.356
gastrointestinal system cancer DOID:3119 0 0.356
disease of cellular proliferation DOID:14566 0 0.356
organ system cancer DOID:0050686 0 0.356
colorectal cancer DOID:9256 0 0.151
colon cancer DOID:219 0 0.151
large intestine cancer DOID:5672 0 0.151
colon carcinoma DOID:1520 0 0.115
disease of anatomical entity DOID:7 0 0.058
musculoskeletal system disease DOID:17 0 0.058
bone development disease DOID:0080006 0 0.058
bone disease DOID:0080001 0 0.058
connective tissue disease DOID:65 0 0.058
osteochondrodysplasia DOID:2256 0 0.036
nervous system disease DOID:863 0 0.034
benign neoplasm DOID:0060072 0 0.033
liver cancer DOID:3571 0 0.020
hepatocellular carcinoma DOID:684 0 0.020
liver carcinoma DOID:686 0 0.020
organ system benign neoplasm DOID:0060085 0 0.017