Rattus norvegicus

0 known processes

Col4a4

collagen, type IV, alpha 4

(Aliases: MGC105542)

Col4a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of signal transduction GO:0009966 318 0.201
rhythmic process GO:0048511 156 0.173
cellular response to endogenous stimulus GO:0071495 377 0.150
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.139
immune system process GO:0002376 204 0.129
homeostatic process GO:0042592 331 0.127
regulation of multicellular organismal development GO:2000026 376 0.119
response to blue light GO:0009637 1 0.114
cellular chemical homeostasis GO:0055082 247 0.113
enzyme linked receptor protein signaling pathway GO:0007167 116 0.110
l glutamate import GO:0051938 2 0.109
response to monosaccharide GO:0034284 159 0.108
regulation of neuron differentiation GO:0045664 208 0.105
neuron projection development GO:0031175 273 0.102
response to carbohydrate GO:0009743 183 0.101
regulation of rna metabolic process GO:0051252 391 0.099
apoptotic process GO:0006915 381 0.099
locomotion GO:0040011 237 0.095
behavior GO:0007610 205 0.091
cell projection organization GO:0030030 302 0.090
regulation of molecular function GO:0065009 398 0.081
neuron development GO:0048666 286 0.080
oxidation reduction process GO:0055114 304 0.079
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.077
bmp signaling pathway GO:0030509 4 0.076
positive regulation of response to stimulus GO:0048584 285 0.075
ion transmembrane transport GO:0034220 365 0.075
development of primary sexual characteristics GO:0045137 107 0.071
transcription from rna polymerase ii promoter GO:0006366 252 0.068
positive regulation of signaling GO:0023056 270 0.068
single organism biosynthetic process GO:0044711 342 0.068
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.067
negative regulation of metabolic process GO:0009892 331 0.066
chemical homeostasis GO:0048878 292 0.066
nucleic acid templated transcription GO:0097659 379 0.065
positive regulation of cell communication GO:0010647 271 0.061
neuron differentiation GO:0030182 368 0.060
regulation of rna biosynthetic process GO:2001141 381 0.059
circadian rhythm GO:0007623 88 0.057
neuron projection morphogenesis GO:0048812 122 0.056
purine containing compound metabolic process GO:0072521 253 0.055
regulation of phosphate metabolic process GO:0019220 349 0.055
carbohydrate derivative metabolic process GO:1901135 346 0.055
organic acid metabolic process GO:0006082 292 0.055
positive regulation of cell proliferation GO:0008284 249 0.054
carboxylic acid metabolic process GO:0019752 289 0.053
coronary vasculature morphogenesis GO:0060977 3 0.052
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
response to glucocorticoid GO:0051384 223 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.050
positive regulation of biosynthetic process GO:0009891 319 0.049
regulation of phosphorus metabolic process GO:0051174 349 0.048
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.048
reproductive process GO:0022414 372 0.047
response to nutrient GO:0007584 248 0.047
response to inorganic substance GO:0010035 377 0.047
anatomical structure morphogenesis GO:0009653 298 0.047
Fly
response to glucose GO:0009749 136 0.046
jak stat cascade GO:0007259 26 0.046
cellular component morphogenesis GO:0032989 155 0.045
regulation of intracellular signal transduction GO:1902531 218 0.044
cell part morphogenesis GO:0032990 123 0.044
cell projection morphogenesis GO:0048858 123 0.044
cellular component biogenesis GO:0044085 368 0.043
regulation of programmed cell death GO:0043067 341 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
positive regulation of nervous system development GO:0051962 178 0.042
transcription dna templated GO:0006351 377 0.042
tissue development GO:0009888 252 0.042
Rat Fly
single organism reproductive process GO:0044702 297 0.042
cellular component movement GO:0006928 248 0.041
amine metabolic process GO:0009308 38 0.041
response to hexose GO:0009746 144 0.041
regulation of heart contraction GO:0008016 48 0.041
rna biosynthetic process GO:0032774 380 0.040
positive regulation of nucleic acid templated transcription GO:1903508 197 0.040
single organism behavior GO:0044708 130 0.039
regulation of cell development GO:0060284 263 0.039
cation transport GO:0006812 382 0.039
regulation of membrane potential GO:0042391 110 0.039
positive regulation of cell development GO:0010720 176 0.039
response to oxidative stress GO:0006979 186 0.039
response to estrogen GO:0043627 232 0.039
cell morphogenesis involved in differentiation GO:0000904 119 0.038
response to corticosteroid GO:0031960 235 0.038
regulation of transcription dna templated GO:0006355 374 0.038
regulation of nervous system development GO:0051960 264 0.037
peptidyl amino acid modification GO:0018193 126 0.036
regulation of apoptotic process GO:0042981 335 0.036
cellular homeostasis GO:0019725 252 0.036
positive regulation of gene expression GO:0010628 244 0.035
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.035
signal transduction by phosphorylation GO:0023014 144 0.034
dendrite development GO:0016358 72 0.034
circulatory system process GO:0003013 183 0.034
regulation of anion transport GO:0044070 43 0.033
regulation of ion transmembrane transporter activity GO:0032412 48 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
response to estradiol GO:0032355 164 0.033
transmembrane transport GO:0055085 412 0.033
potassium ion transport GO:0006813 97 0.033
regulation of neurogenesis GO:0050767 247 0.033
rna metabolic process GO:0016070 406 0.032
heart contraction GO:0060047 57 0.032
regulation of immune system process GO:0002682 123 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
response to mechanical stimulus GO:0009612 134 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
locomotor rhythm GO:0045475 1 0.031
response to biotic stimulus GO:0009607 226 0.031
cation homeostasis GO:0055080 195 0.031
response to acid chemical GO:0001101 222 0.031
negative regulation of programmed cell death GO:0043069 183 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
fat cell proliferation GO:0070341 2 0.030
programmed cell death GO:0012501 392 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
cell motility GO:0048870 202 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.029
inorganic ion transmembrane transport GO:0098660 229 0.029
response to ketone GO:1901654 182 0.029
glucose homeostasis GO:0042593 75 0.029
nucleotide metabolic process GO:0009117 279 0.029
negative regulation of gene expression GO:0010629 199 0.029
intracellular signal transduction GO:0035556 314 0.029
reproductive system development GO:0061458 128 0.028
regulation of cell proliferation GO:0042127 359 0.028
nitrogen compound transport GO:0071705 229 0.028
cellular component assembly GO:0022607 360 0.028
regulation of ion transport GO:0043269 245 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
protein oligomerization GO:0051259 191 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
secretion GO:0046903 307 0.027
optic nerve development GO:0021554 3 0.027
response to cytokine GO:0034097 215 0.027
cellular response to tumor necrosis factor GO:0071356 46 0.027
response to alkaloid GO:0043279 132 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
regulation of bmp signaling pathway GO:0030510 2 0.026
negative regulation of molecular function GO:0044092 133 0.026
cellular response to stress GO:0033554 269 0.026
regulation of heart growth GO:0060420 12 0.026
cellular response to hexose stimulus GO:0071331 65 0.026
protein phosphorylation GO:0006468 345 0.025
response to nutrient levels GO:0031667 370 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
positive regulation of brown fat cell proliferation GO:0070349 1 0.025
positive regulation of developmental process GO:0051094 283 0.025
protein complex biogenesis GO:0070271 263 0.025
cellular amine metabolic process GO:0044106 38 0.025
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.025
negative regulation of cell death GO:0060548 229 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
response to mineralocorticoid GO:0051385 49 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
organ formation GO:0048645 3 0.024
membrane hyperpolarization GO:0060081 11 0.024
cell type specific apoptotic process GO:0097285 134 0.024
response to extracellular stimulus GO:0009991 380 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
nucleobase containing compound catabolic process GO:0034655 152 0.024
amino acid transport GO:0006865 70 0.024
reproduction GO:0000003 245 0.024
negative regulation of signaling GO:0023057 157 0.023
response to lipopolysaccharide GO:0032496 191 0.023
positive regulation of molecular function GO:0044093 230 0.023
response to radiation GO:0009314 137 0.023
negative regulation of cell communication GO:0010648 158 0.023
regulation of gtpase activity GO:0043087 57 0.023
negative regulation of apoptotic process GO:0043066 181 0.023
response to decreased oxygen levels GO:0036293 237 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
cellular response to external stimulus GO:0071496 118 0.022
chemotaxis GO:0006935 66 0.022
carbohydrate homeostasis GO:0033500 75 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
positive regulation of fat cell proliferation GO:0070346 1 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
gonad development GO:0008406 104 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
regulation of organ formation GO:0003156 2 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
response to growth factor GO:0070848 189 0.021
oxoacid metabolic process GO:0043436 290 0.021
regulation of neuron projection development GO:0010975 161 0.021
negative regulation of rna metabolic process GO:0051253 123 0.020
response to bacterium GO:0009617 200 0.020
response to external biotic stimulus GO:0043207 221 0.020
sensory perception GO:0007600 101 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
positive regulation of potassium ion transmembrane transport GO:1901381 4 0.020
regulation of protein kinase activity GO:0045859 105 0.020
heart process GO:0003015 57 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
negative regulation of signal transduction GO:0009968 83 0.020
response to hypoxia GO:0001666 231 0.020
regulation of immunoglobulin production GO:0002637 4 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
glutamate receptor signaling pathway GO:0007215 43 0.019
immune response GO:0006955 104 0.019
developmental growth GO:0048589 100 0.019
biological adhesion GO:0022610 110 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
cell morphogenesis GO:0000902 142 0.019
brain development GO:0007420 247 0.019
renal system development GO:0072001 67 0.019
Human Fly
regulation of catalytic activity GO:0050790 304 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
regulation of dendrite development GO:0050773 59 0.019
ras protein signal transduction GO:0007265 29 0.019
muscle cell proliferation GO:0033002 84 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
regulation of transmembrane transporter activity GO:0022898 49 0.018
positive regulation of signal transduction GO:0009967 175 0.018
positive regulation of cellular component biogenesis GO:0044089 55 0.018
innate immune response GO:0045087 35 0.018
purine ribonucleotide catabolic process GO:0009154 136 0.018
organophosphate metabolic process GO:0019637 370 0.018
regulation of muscle system process GO:0090257 79 0.018
response to electrical stimulus GO:0051602 56 0.018
response to tumor necrosis factor GO:0034612 56 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
regulation of protein metabolic process GO:0051246 289 0.018
defense response GO:0006952 194 0.018
nucleoside metabolic process GO:0009116 179 0.018
regulation of locomotion GO:0040012 148 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
regulation of homeostatic process GO:0032844 101 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
protein complex subunit organization GO:0071822 302 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
negative regulation of innate immune response GO:0045824 4 0.017
regulation of fat cell proliferation GO:0070344 1 0.017
response to hydrogen peroxide GO:0042542 89 0.017
multi organism reproductive process GO:0044703 262 0.017
developmental process involved in reproduction GO:0003006 159 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
axon development GO:0061564 96 0.017
neuromuscular process GO:0050905 2 0.017
cell fate determination GO:0001709 2 0.017
salivary gland development GO:0007431 3 0.017
regulation of cardiac muscle cell proliferation GO:0060043 6 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
protein complex assembly GO:0006461 263 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
positive regulation of ion transport GO:0043270 94 0.017
cellular response to oxygen levels GO:0071453 60 0.017
ribose phosphate biosynthetic process GO:0046390 87 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
positive regulation of isotype switching GO:0045830 1 0.017
gtp catabolic process GO:0006184 71 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
sex differentiation GO:0007548 113 0.017
multicellular organismal reproductive process GO:0048609 233 0.016
blood circulation GO:0008015 183 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
brown fat cell proliferation GO:0070342 2 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
cell adhesion GO:0007155 110 0.016
growth GO:0040007 165 0.016
regulation of cell differentiation GO:0045595 320 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
response to other organism GO:0051707 220 0.016
regulation of transmembrane transport GO:0034762 122 0.016
positive regulation of hydrolase activity GO:0051345 86 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
positive regulation of immunoglobulin production GO:0002639 4 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
neurological system process GO:0050877 219 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
positive regulation of cellular component organization GO:0051130 200 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
hemopoiesis GO:0030097 34 0.015
cellular response to carbohydrate stimulus GO:0071322 72 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
organ regeneration GO:0031100 101 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
ion homeostasis GO:0050801 212 0.015
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.015
regulation of oxidoreductase activity GO:0051341 11 0.015
multicellular organism reproduction GO:0032504 233 0.015
mapk cascade GO:0000165 140 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
multi multicellular organism process GO:0044706 138 0.015
muscle structure development GO:0061061 87 0.015
Fly
regulation of tube size GO:0035150 89 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
regulation of anatomical structure size GO:0090066 135 0.014
regulation of kinase activity GO:0043549 117 0.014
cellular glucose homeostasis GO:0001678 66 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
cellular catabolic process GO:0044248 295 0.014
organic substance catabolic process GO:1901575 316 0.014
secretion by cell GO:0032940 248 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
response to nicotine GO:0035094 51 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
cardiac muscle cell contraction GO:0086003 10 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
epithelium development GO:0060429 96 0.014
Rat Fly
metal ion transport GO:0030001 289 0.014
cellular ketone metabolic process GO:0042180 51 0.014
positive regulation of cell death GO:0010942 184 0.014
acute inflammatory response GO:0002526 58 0.014
response to vitamin GO:0033273 131 0.014
regulation of cell growth GO:0001558 85 0.014
potassium ion transmembrane transport GO:0071805 71 0.014
negative regulation of response to stimulus GO:0048585 155 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
regulation of cardiac muscle contraction GO:0055117 17 0.013
regulation of cellular component organization GO:0051128 368 0.013
regulation of transporter activity GO:0032409 50 0.013
regulation of body fluid levels GO:0050878 90 0.013
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.013
cellular potassium ion transport GO:0071804 72 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
regulation of hormone levels GO:0010817 187 0.013
cofactor metabolic process GO:0051186 95 0.013
aging GO:0007568 241 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of growth GO:0040008 105 0.013
organophosphate catabolic process GO:0046434 148 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
carboxylic acid transport GO:0046942 115 0.013
cellular response to monosaccharide stimulus GO:0071326 67 0.013
epithelial cell differentiation GO:0030855 71 0.013
Rat
response to amino acid GO:0043200 75 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
protein tetramerization GO:0051262 38 0.012
negative regulation of immune system process GO:0002683 39 0.012
axonogenesis GO:0007409 71 0.012
positive regulation of potassium ion transport GO:0043268 13 0.012
reproductive structure development GO:0048608 128 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.012
specification of organ identity GO:0010092 2 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
regulation of hydrolase activity GO:0051336 143 0.012
erbb signaling pathway GO:0038127 23 0.012
positive regulation of transport GO:0051050 245 0.012
dendrite morphogenesis GO:0048813 43 0.012
motor neuron axon guidance GO:0008045 1 0.012
developmental induction GO:0031128 2 0.012
regulation of blood circulation GO:1903522 110 0.012
regulation of system process GO:0044057 208 0.012
metal ion homeostasis GO:0055065 186 0.012
nucleotide catabolic process GO:0009166 139 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
head development GO:0060322 247 0.012
regulation of striated muscle contraction GO:0006942 21 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
multicellular organismal homeostasis GO:0048871 49 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
response to ethanol GO:0045471 162 0.011
central nervous system development GO:0007417 311 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
lipid metabolic process GO:0006629 283 0.011
response to testosterone GO:0033574 55 0.011
calcium ion homeostasis GO:0055074 162 0.011
axis specification GO:0009798 4 0.011
organic acid transport GO:0015849 116 0.011
inflammatory response GO:0006954 150 0.011
regulation of brown fat cell proliferation GO:0070347 1 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
multicellular organismal signaling GO:0035637 44 0.011
regulation of mapk cascade GO:0043408 116 0.011
cellular ion homeostasis GO:0006873 184 0.011
regulation of organelle organization GO:0033043 80 0.011
positive regulation of immune system process GO:0002684 90 0.011
cation transmembrane transport GO:0098655 263 0.011
negative regulation of developmental process GO:0051093 125 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
cellular response to lipid GO:0071396 201 0.011
male gonad development GO:0008584 59 0.011
regulation of cell projection organization GO:0031344 175 0.011
cellular response to hypoxia GO:0071456 51 0.011
response to toxic substance GO:0009636 133 0.011
response to activity GO:0014823 73 0.011
cellular response to mechanical stimulus GO:0071260 48 0.011
regulation of monooxygenase activity GO:0032768 8 0.011
positive regulation of growth GO:0045927 55 0.011
myelination GO:0042552 39 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
metanephric comma shaped body morphogenesis GO:0072278 2 0.010
synaptic transmission glutamatergic GO:0035249 33 0.010
response to starvation GO:0042594 59 0.010
regulation of protein modification process GO:0031399 194 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
cellular amino acid metabolic process GO:0006520 107 0.010
eye morphogenesis GO:0048592 4 0.010
regulation of muscle contraction GO:0006937 53 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
macromolecular complex assembly GO:0065003 273 0.010
positive regulation of cell motility GO:2000147 97 0.010
peptide transport GO:0015833 97 0.010
cellular response to glucose stimulus GO:0071333 65 0.010
response to ph GO:0009268 27 0.010

Col4a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
kidney disease DOID:557 0 0.040
urinary system disease DOID:18 0 0.040
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.030
disease of metabolism DOID:0014667 0 0.025
inherited metabolic disorder DOID:655 0 0.014
renal tubular transport disease DOID:447 0 0.012
hypertension DOID:10763 0 0.012
cardiovascular system disease DOID:1287 0 0.012
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012