IMP
Process View
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "regulation of transmembrane receptor protein serine threonine kinase signaling pathway"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Lamc1 | laminin, gamma 1 | 0.728 | ||
| Ece1 | endothelin converting enzyme 1 | 0.601 | ||
| Pmepa1 | prostate transmembrane protein, androgen induced 1 | 0.493 | ||
| Flt1 | FMS-related tyrosine kinase 1 | 0.353 | ||
| Prkch | protein kinase C, eta | 0.269 | ||
| Smad7 | SMAD family member 7 | 0.231 | ||
| Cish | cytokine inducible SH2-containing protein | 0.219 | ||
| Mcam | melanoma cell adhesion molecule | 0.182 | ||
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.175 | ||
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.173 | ||
| Ucp3 | uncoupling protein 3 (mitochondrial, proton carrier) | 0.165 | ||
| Pde4a | phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) | 0.155 | ||
| Jak2 | Janus kinase 2 | 0.133 | ||
| Agtr1a | angiotensin II receptor, type 1a | 0.132 | ||
| Col4a1 | collagen, type IV, alpha 1 | 0.131 | ||
| Stat6 | signal transducer and activator of transcription 6 | 0.129 | ||
| Emp1 | epithelial membrane protein 1 | 0.117 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.111 | ||
| Gata6 | GATA binding protein 6 | 0.109 | ||
| Cand1 | cullin-associated and neddylation-dissociated 1 | 0.095 | ||
| Pecam1 | platelet/endothelial cell adhesion molecule 1 | 0.092 | ||
| Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.067 | ||
| Efnb1 | ephrin B1 | 0.066 | ||
| Eng | endoglin | 0.065 | ||
| Fbln5 | fibulin 5 | 0.064 | ||
| Slit3 | slit homolog 3 (Drosophila) | 0.064 | ||
| Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.058 | ||
| Akt1s1 | AKT1 substrate 1 (proline-rich) | 0.056 | ||
| Ednra | endothelin receptor type A | 0.054 | ||
| Kcnq3 | potassium voltage-gated channel, KQT-like subfamily, member 3 | 0.054 | ||
| Vegfa | vascular endothelial growth factor A | 0.051 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.050 | Rat | |
| Timp3 | TIMP metallopeptidase inhibitor 3 | 0.049 | ||
| Col4a4 | collagen, type IV, alpha 4 | 0.048 | ||
| Timp2 | TIMP metallopeptidase inhibitor 2 | 0.045 | ||
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.045 | ||
| Sox17 | SRY (sex determining region Y)-box 17 | 0.042 | ||
| Pdpn | podoplanin | 0.042 | ||
| Smad6 | SMAD family member 6 | 0.041 | Rat | |
| Eif4ebp2 | eukaryotic translation initiation factor 4E binding protein 2 | 0.040 | ||
| Tgfbr3 | transforming growth factor, beta receptor III | 0.039 | ||
| Rara | retinoic acid receptor, alpha | 0.038 | ||
| Amd1 | adenosylmethionine decarboxylase 1 | 0.036 | ||
| Serpinh1 | serine (or cysteine) peptidase inhibitor, clade H, member 1 | 0.034 | ||
| Socs2 | suppressor of cytokine signaling 2 | 0.034 | ||
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.033 | ||
| Ddr2 | discoidin domain receptor tyrosine kinase 2 | 0.033 | ||
| Atp7b | ATPase, Cu++ transporting, beta polypeptide | 0.032 | ||
| Met | met proto-oncogene | 0.029 | ||
| Abcc1 | ATP-binding cassette, subfamily C (CFTR/MRP), member 1 | 0.029 | ||
| Thbd | thrombomodulin | 0.029 | ||
| Tp53 | tumor protein p53 | 0.029 | ||
| Nfia | nuclear factor I/A | 0.029 | ||
| Adra2b | adrenergic, alpha-2B-, receptor | 0.028 | ||
| Prph2 | peripherin 2 | 0.028 | ||
| Lyve1 | lymphatic vessel endothelial hyaluronan receptor 1 | 0.028 | ||
| Myh9 | myosin, heavy chain 9, non-muscle | 0.028 | ||
| Hand2 | heart and neural crest derivatives expressed 2 | 0.028 | ||
| Jub | jub, ajuba homolog (Xenopus laevis) | 0.028 | ||
| Impa1 | Inositol (myo)-1(or 4)-monophosphatase 1 | 0.028 | ||
| Loxl1 | lysyl oxidase-like 1 | 0.027 | ||
| Fam198b | family with sequence similarity 198, member B | 0.027 | ||
| Cdh5 | cadherin 5 | 0.026 | ||
| Dnajb11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.026 | ||
| Hsp90b1 | heat shock protein 90, beta, member 1 | 0.025 | ||
| Tgfb3 | transforming growth factor, beta 3 | 0.025 | ||
| Hpcal4 | hippocalcin-like 4 | 0.025 | ||
| Npr3 | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 0.025 | ||
| Gsk3b | glycogen synthase kinase 3 beta | 0.025 | ||
| Igf2r | insulin-like growth factor 2 receptor | 0.024 | ||
| Dnaja2 | DnaJ (Hsp40) homolog, subfamily A, member 2 | 0.024 | ||
| Gata4 | GATA binding protein 4 | 0.024 | ||
| Mr1 | major histocompatibility complex, class I-related | 0.024 | ||
| Ncan | neurocan | 0.024 | ||
| Wt1 | Wilms tumor 1 | 0.023 | ||
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.023 | ||
| Rest | RE1-silencing transcription factor | 0.023 | ||
| Dlg4 | discs, large homolog 4 (Drosophila) | 0.023 | ||
| Sox7 | SRY (sex determining region Y)-box 7 | 0.023 | ||
| Foxq1 | forkhead box Q1 | 0.022 | ||
| Mafb | v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian) | 0.022 | ||
| Dnaja1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.022 | ||
| RT1-M4 | RT1 class Ib, locus M4 | 0.022 | ||
| Fgf1 | fibroblast growth factor 1 | 0.022 | ||
| Ssbp4 | single stranded DNA binding protein 4 | 0.022 | ||
| Ets1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.022 | ||
| Qk | quaking | 0.022 | ||
| Map3k3 | mitogen activated protein kinase kinase kinase 3 | 0.022 | ||
| Tceb3 | transcription elongation factor B (SIII), polypeptide 3 | 0.021 | ||
| Olfml2b | olfactomedin-like 2B | 0.021 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.021 | ||
| Kcnj9 | potassium inwardly-rectifying channel, subfamily J, member 9 | 0.021 | Fly | |
| Slc12a1 | solute carrier family 12 (sodium/potassium/chloride transporters), member 1 | 0.021 | ||
| Gja3 | gap junction protein, alpha 3 | 0.020 | ||
| Klf13 | Kruppel-like factor 13 | 0.020 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.020 | ||
| Dlgap2 | discs, large (Drosophila) homolog-associated protein 2 | 0.020 | ||
| Nox4 | NADPH oxidase 4 | 0.020 | ||
| Pias2 | protein inhibitor of activated STAT, 2 | 0.019 | ||
| Nes | nestin | 0.019 | ||
| LOC305633 | similar to Antxr2 protein | 0.019 | ||
| Dlgap4 | discs, large homolog-associated protein 4 (Drosophila) | 0.019 | ||
| Usf2 | upstream transcription factor 2, c-fos interacting | 0.019 | ||
| Ntn1 | netrin 1 | 0.019 | ||
| Ednrb | endothelin receptor type B | 0.019 | ||
| Vegfc | vascular endothelial growth factor C | 0.019 | ||
| Syt4 | synaptotagmin IV | 0.019 | ||
| Samd4b | sterile alpha motif domain containing 4B | 0.019 | ||
| Smad2 | SMAD family member 2 | 0.019 | Human Rat | |
| Kcnk3 | potassium channel, subfamily K, member 3 | 0.019 | ||
| Htr7 | 5-hydroxytryptamine (serotonin) receptor 7 | 0.018 | ||
| Igfbp6 | insulin-like growth factor binding protein 6 | 0.018 | ||
| Eif4enif1 | eukaryotic translation initiation factor 4E nuclear import factor 1 | 0.018 | ||
| Foxs1 | forkhead box S1 | 0.018 | ||
| Psen1 | presenilin 1 | 0.017 | ||
| Slc14a1 | solute carrier family 14 (urea transporter), member 1 | 0.017 | ||
| Pard3 | par-3 (partitioning defective 3) homolog (C. elegans) | 0.017 | ||
| Prdm2 | PR domain containing 2, with ZNF domain | 0.017 | ||
| Gatad1 | GATA zinc finger domain containing 1 | 0.017 | ||
| Aif1l | allograft inflammatory factor 1-like | 0.016 | ||
| Nrp1 | neuropilin 1 | 0.016 | ||
| Ggt5 | gamma-glutamyltransferase 5 | 0.016 | ||
| Pik3r1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.016 | ||
| Apba1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 0.016 | ||
| Vcp | valosin-containing protein | 0.016 | ||
| Dysf | dysferlin | 0.015 | ||
| Pax8 | paired box 8 | 0.015 | ||
| Ahr | aryl hydrocarbon receptor | 0.015 | ||
| Znf503 | zinc finger protein 503 | 0.015 | ||
| Scn1b | sodium channel, voltage-gated, type I, beta | 0.014 | ||
| Gnb3 | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 0.014 | ||
| Tagln3 | transgelin 3 | 0.014 | ||
| Cept1 | choline/ethanolamine phosphotransferase 1 | 0.014 | ||
| Rab7a | RAB7A, member RAS oncogene family | 0.014 | ||
| Defb1 | defensin beta 1 | 0.014 | ||
| Bmp2 | bone morphogenetic protein 2 | 0.014 | Human | |
| Ncaph2 | non-SMC condensin II complex, subunit H2 | 0.014 | ||
| Maf | v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) | 0.014 | ||
| RGD1560871 | similar to plexin 1 | 0.014 | ||
| RGD1311307 | similar to 1300014I06Rik protein | 0.014 | ||
| Jak1 | Janus kinase 1 | 0.014 | ||
| Adrb1 | adrenergic, beta-1-, receptor | 0.014 | ||
| Dyrk1a | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.014 | ||
| Raf1 | v-raf-leukemia viral oncogene 1 | 0.014 | ||
| Scarf2 | scavenger receptor class F, member 2 | 0.014 | ||
| Bmp7 | bone morphogenetic protein 7 | 0.013 | Human | |
| Nfic | nuclear factor I/C | 0.013 | ||
| RGD1562844 | similar to serine (or cysteine) proteinase inhibitor, clade B, member 9 | 0.013 | ||
| Gper | G protein-coupled estrogen receptor 1 | 0.013 | ||
| Rgs19 | regulator of G-protein signaling 19 | 0.013 | ||
| Tcf3 | transcription factor 3 | 0.013 | ||
| Wnt6 | wingless-type MMTV integration site family, member 6 | 0.013 | ||
| Pdia6 | protein disulfide isomerase family A, member 6 | 0.013 | ||
| Itga1 | integrin, alpha 1 | 0.013 | ||
| Nln | neurolysin (metallopeptidase M3 family) | 0.013 | ||
| Pdia3 | protein disulfide isomerase family A, member 3 | 0.013 | ||
| Maea | macrophage erythroblast attacher | 0.013 | ||
| Nlgn1 | neuroligin 1 | 0.013 | ||
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.013 | ||
| Igfbp5 | insulin-like growth factor binding protein 5 | 0.013 | ||
| Kcnt1 | potassium channel, subfamily T, member 1 | 0.013 | ||
| Foxd1 | forkhead box D1 | 0.013 | ||
| Ehf | ets homologous factor | 0.013 | ||
| Col18a1 | collagen, type XVIII, alpha 1 | 0.013 | ||
| Socs3 | suppressor of cytokine signaling 3 | 0.013 | ||
| Tgm2 | transglutaminase 2, C polypeptide | 0.013 | ||
| Myo1c | myosin IC | 0.012 | ||
| Mmp23 | matrix metallopeptidase 23 | 0.012 | ||
| Enpep | glutamyl aminopeptidase | 0.012 | ||
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.012 | ||
| Mapk10 | mitogen activated protein kinase 10 | 0.012 | ||
| Dlgap3 | discs, large (Drosophila) homolog-associated protein 3 | 0.012 | ||
| Kif27 | kinesin family member 27 | 0.012 | ||
| Pdlim5 | PDZ and LIM domain 5 | 0.012 | ||
| Bdnf | brain-derived neurotrophic factor | 0.012 | ||
| Pdgfa | platelet-derived growth factor alpha polypeptide | 0.012 | ||
| Lamb2 | laminin, beta 2 | 0.012 | ||
| Baiap2 | BAI1-associated protein 2 | 0.012 | ||
| Col12a1 | collagen, type XII, alpha 1 | 0.012 | ||
| Gsr | glutathione reductase | 0.012 | ||
| Cacna1c | calcium channel, voltage-dependent, L type, alpha 1C subunit | 0.012 | ||
| Mgat1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase | 0.012 | ||
| Gabra4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 | 0.012 | ||
| Gria1 | glutamate receptor, ionotropic, AMPA 1 | 0.012 | ||
| Dmd | dystrophin | 0.012 | ||
| Fam180a | family with sequence similarity 180, member A | 0.012 | ||
| Fbln2 | fibulin 2 | 0.012 | ||
| Mapre1 | microtubule-associated protein, RP/EB family, member 1 | 0.011 | ||
| RGD1305793 | similar to hypothetical protein FLJ20154 | 0.011 | ||
| Gucy2c | guanylate cyclase 2C | 0.011 | ||
| Ppard | peroxisome proliferator-activated receptor delta | 0.011 | ||
| Eaf1 | ELL associated factor 1 | 0.011 | ||
| Col5a1 | collagen, type V, alpha 1 | 0.011 | ||
| Il1rap | interleukin 1 receptor accessory protein | 0.011 | ||
| Lrp1 | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 0.011 | ||
| Foxe1 | forkhead box E1 (thyroid transcription factor 2) | 0.011 | ||
| Slc34a3 | solute carrier family 34 (sodium phosphate), member 3 | 0.011 | ||
| Rragc | Ras-related GTP binding C | 0.011 | ||
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.011 | ||
| Gpr176 | G protein-coupled receptor 176 | 0.011 | ||
| Mprip | myosin phosphatase Rho interacting protein | 0.011 | ||
| Smad1 | SMAD family member 1 | 0.011 | Rat | |
| Actn4 | actinin alpha 4 | 0.011 | ||
| Gpr116 | G protein-coupled receptor 116 | 0.010 | ||
| Mpp2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.010 | ||
| Doc2a | double C2-like domains, alpha | 0.010 | ||
| Ptprk | protein tyrosine phosphatase, receptor type, K, extracellular region | 0.010 | ||
| Plvap | plasmalemma vesicle associated protein | 0.010 | ||
| Ptpru | protein tyrosine phosphatase, receptor type, U | 0.010 | ||
| Chrna5 | cholinergic receptor, nicotinic, alpha 5 | 0.010 | ||
| Dchs1 | dachsous 1 (Drosophila) | 0.010 | ||
| Stx12 | syntaxin 12 | 0.010 | ||
| Hspa13 | heat shock protein 13 | 0.010 | ||
| Hsph1 | heat shock 105/110 protein 1 | 0.010 | ||
| Serpinf1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.010 | ||
| Canx | calnexin | 0.010 | ||
| Cgm4 | carcinoembryonic antigen gene family 4 | 0.010 |