Rattus norvegicus

193 known processes

Mapk8

mitogen-activated protein kinase 8

(Aliases: JNK)

Mapk8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of signaling GO:0023056 270 0.347
Mouse
stress activated protein kinase signaling cascade GO:0031098 37 0.239
intracellular signal transduction GO:0035556 314 0.222
cell cell signaling GO:0007267 335 0.209
regulation of stress activated mapk cascade GO:0032872 23 0.183
Rat Fly
regulation of programmed cell death GO:0043067 341 0.177
positive regulation of cell communication GO:0010647 271 0.164
Mouse
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.158
embryonic skeletal system development GO:0048706 3 0.152
organelle organization GO:0006996 266 0.147
regulation of intracellular signal transduction GO:1902531 218 0.146
Rat Fly
positive regulation of multicellular organismal process GO:0051240 387 0.141
Mouse Rat
mapk cascade GO:0000165 140 0.140
secretion GO:0046903 307 0.132
Rat
jnk cascade GO:0007254 28 0.130
circulatory system development GO:0072359 134 0.130
organophosphate metabolic process GO:0019637 370 0.128
rhythmic process GO:0048511 156 0.126
programmed cell death GO:0012501 392 0.124
neuron development GO:0048666 286 0.123
hormone secretion GO:0046879 115 0.123
positive regulation of phosphate metabolic process GO:0045937 262 0.120
Rat
response to lipopolysaccharide GO:0032496 191 0.119
Human Rat
regulation of hormone levels GO:0010817 187 0.117
cell projection organization GO:0030030 302 0.115
transcription from rna polymerase ii promoter GO:0006366 252 0.113
Yeast Rat
anatomical structure morphogenesis GO:0009653 298 0.110
Yeast Rat Fly
regulation of phosphorus metabolic process GO:0051174 349 0.108
Rat Fly
aromatic compound catabolic process GO:0019439 168 0.108
ribose phosphate metabolic process GO:0019693 235 0.104
regulation of protein phosphorylation GO:0001932 183 0.103
Rat Fly
apoptotic process GO:0006915 381 0.103
regulation of secretion GO:0051046 224 0.100
Rat
regulation of signal transduction GO:0009966 318 0.099
Mouse Rat Fly
response to carbohydrate GO:0009743 183 0.098
Rat
regulation of mapk cascade GO:0043408 116 0.096
Rat Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.095
regulation of cellular component organization GO:0051128 368 0.094
ribonucleotide catabolic process GO:0009261 136 0.093
regulation of phosphorylation GO:0042325 248 0.093
Rat Fly
protein autophosphorylation GO:0046777 66 0.090
Rat
establishment of protein localization GO:0045184 141 0.089
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.089
Rat
regulation of neuron death GO:1901214 115 0.089
purine nucleotide metabolic process GO:0006163 229 0.087
positive regulation of transport GO:0051050 245 0.087
Rat
multicellular organismal reproductive process GO:0048609 233 0.086
Fly
cellular component biogenesis GO:0044085 368 0.086
organic acid metabolic process GO:0006082 292 0.086
Rat
regulation of response to stress GO:0080134 126 0.085
Rat Fly
gland development GO:0048732 155 0.084
regulation of secretion by cell GO:1903530 208 0.084
cardiovascular system development GO:0072358 134 0.083
nucleoside phosphate catabolic process GO:1901292 140 0.083
carbohydrate derivative metabolic process GO:1901135 346 0.082
nucleoside phosphate metabolic process GO:0006753 283 0.082
rna metabolic process GO:0016070 406 0.081
neuron differentiation GO:0030182 368 0.081
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.079
purine ribonucleotide metabolic process GO:0009150 227 0.079
reproduction GO:0000003 245 0.078
Yeast Fly
ribonucleoside triphosphate catabolic process GO:0009203 122 0.077
growth GO:0040007 165 0.076
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.075
single organism reproductive process GO:0044702 297 0.074
Yeast Fly
neuron projection development GO:0031175 273 0.074
cell projection morphogenesis GO:0048858 123 0.074
Fly
purine containing compound metabolic process GO:0072521 253 0.074
negative regulation of signaling GO:0023057 157 0.074
Fly
response to bacterium GO:0009617 200 0.073
Human Rat Fly
signal transduction by phosphorylation GO:0023014 144 0.073
regulation of nucleic acid templated transcription GO:1903506 380 0.072
cellular catabolic process GO:0044248 295 0.071
Fly
regulation of phosphate metabolic process GO:0019220 349 0.071
Rat Fly
nucleoside triphosphate metabolic process GO:0009141 144 0.070
nucleotide metabolic process GO:0009117 279 0.070
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.070
regulation of response to external stimulus GO:0032101 106 0.070
synaptic growth at neuromuscular junction GO:0051124 1 0.070
regeneration GO:0031099 163 0.069
Fly
negative regulation of cell communication GO:0010648 158 0.069
Fly
single organism biosynthetic process GO:0044711 342 0.068
Yeast Rat
positive regulation of cell death GO:0010942 184 0.067
purine ribonucleotide catabolic process GO:0009154 136 0.067
multicellular organism reproduction GO:0032504 233 0.066
Fly
regulation of system process GO:0044057 208 0.066
regulation of hormone secretion GO:0046883 106 0.066
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.065
Rat Fly
vasculature development GO:0001944 70 0.064
regulation of cellular localization GO:0060341 263 0.062
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.062
Rat
neurological system process GO:0050877 219 0.062
glycosyl compound metabolic process GO:1901657 182 0.062
regulation of jnk cascade GO:0046328 19 0.061
Rat Fly
stress activated mapk cascade GO:0051403 35 0.060
nucleoside metabolic process GO:0009116 179 0.060
negative regulation of biosynthetic process GO:0009890 168 0.059
Rat
neuron death GO:0070997 127 0.059
hormone transport GO:0009914 121 0.058
neuron neuron synaptic transmission GO:0007270 60 0.058
cellular response to oxygen containing compound GO:1901701 386 0.058
Human Mouse Rat Fly
purine ribonucleoside metabolic process GO:0046128 168 0.058
cellular response to lipid GO:0071396 201 0.057
Human Rat
single organism intracellular transport GO:1902582 166 0.057
Rat
regulation of rna biosynthetic process GO:2001141 381 0.056
membrane organization GO:0061024 94 0.056
Fly
positive regulation of nucleotide metabolic process GO:0045981 91 0.056
response to external biotic stimulus GO:0043207 221 0.056
Human Rat Fly
positive regulation of apoptotic process GO:0043065 154 0.056
ras protein signal transduction GO:0007265 29 0.055
response to nutrient GO:0007584 248 0.055
transcription dna templated GO:0006351 377 0.054
synapse organization GO:0050808 46 0.054
rna biosynthetic process GO:0032774 380 0.053
single organism cellular localization GO:1902580 102 0.053
Rat Worm
glycosyl compound catabolic process GO:1901658 126 0.053
learning GO:0007612 33 0.052
ribonucleotide metabolic process GO:0009259 231 0.051
regulation of molecular function GO:0065009 398 0.051
Human Rat Fly
response to ketone GO:1901654 182 0.050
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.049
positive regulation of developmental process GO:0051094 283 0.049
Mouse Rat
positive regulation of biosynthetic process GO:0009891 319 0.049
positive regulation of signal transduction GO:0009967 175 0.049
Mouse
response to corticosteroid GO:0031960 235 0.048
nucleobase containing compound catabolic process GO:0034655 152 0.048
regulation of purine nucleotide metabolic process GO:1900542 115 0.048
nucleic acid templated transcription GO:0097659 379 0.048
catabolic process GO:0009056 351 0.048
Fly
response to extracellular stimulus GO:0009991 380 0.047
response to molecule of bacterial origin GO:0002237 194 0.047
Human Rat
positive regulation of neuron death GO:1901216 43 0.047
positive regulation of molecular function GO:0044093 230 0.047
Human Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.046
Yeast Rat
protein localization GO:0008104 191 0.046
Human Rat
response to metal ion GO:0010038 253 0.046
Mouse Fly
organophosphate catabolic process GO:0046434 148 0.046
positive regulation of neuron apoptotic process GO:0043525 33 0.045
ribonucleoside triphosphate metabolic process GO:0009199 141 0.045
heterocycle catabolic process GO:0046700 167 0.045
cellular component morphogenesis GO:0032989 155 0.045
Yeast Rat Fly
peptide hormone secretion GO:0030072 84 0.044
synapse assembly GO:0007416 29 0.043
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.043
Rat
cell part morphogenesis GO:0032990 123 0.043
Fly
learning or memory GO:0007611 90 0.043
organophosphate biosynthetic process GO:0090407 143 0.043
embryonic skeletal system morphogenesis GO:0048704 3 0.042
response to wounding GO:0009611 254 0.042
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
cellular macromolecule localization GO:0070727 122 0.042
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.041
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.041
Human Rat Fly
ovulation cycle GO:0042698 67 0.041
vesicle mediated transport GO:0016192 181 0.041
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.041
Rat
anatomical structure formation involved in morphogenesis GO:0048646 83 0.040
Yeast Fly
regulation of cellular response to stress GO:0080135 49 0.040
Rat Fly
anterior posterior pattern specification GO:0009952 1 0.040
cell type specific apoptotic process GO:0097285 134 0.040
regulation of protein kinase activity GO:0045859 105 0.040
Fly
regulation of catalytic activity GO:0050790 304 0.039
Human Rat Fly
regulation of dna metabolic process GO:0051052 60 0.039
nitrogen compound transport GO:0071705 229 0.039
cell growth GO:0016049 104 0.039
Fly
single organism membrane organization GO:0044802 74 0.039
secretion by cell GO:0032940 248 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
Yeast Rat
behavior GO:0007610 205 0.039
cellular component assembly GO:0022607 360 0.039
cellular response to endogenous stimulus GO:0071495 377 0.038
organonitrogen compound catabolic process GO:1901565 179 0.038
protein transport GO:0015031 132 0.038
Rat
positive regulation of programmed cell death GO:0043068 157 0.037
regulation of protein metabolic process GO:0051246 289 0.037
Human Rat Fly
cellular response to stress GO:0033554 269 0.037
blood vessel development GO:0001568 69 0.036
regulation of nucleoside metabolic process GO:0009118 66 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
Rat
response to biotic stimulus GO:0009607 226 0.036
Human Rat Fly
small gtpase mediated signal transduction GO:0007264 36 0.036
reproductive process GO:0022414 372 0.036
Yeast Fly
regulation of cell development GO:0060284 263 0.036
Rat
purine nucleoside metabolic process GO:0042278 169 0.036
purine nucleoside catabolic process GO:0006152 124 0.036
negative regulation of programmed cell death GO:0043069 183 0.036
positive regulation of cellular protein metabolic process GO:0032270 167 0.036
Rat
brain development GO:0007420 247 0.036
signal release GO:0023061 145 0.036
regulation of protein modification process GO:0031399 194 0.035
Human Rat Fly
circadian rhythm GO:0007623 88 0.035
response to glucocorticoid GO:0051384 223 0.035
purine nucleoside triphosphate metabolic process GO:0009144 141 0.035
cognition GO:0050890 92 0.034
synaptic transmission GO:0007268 235 0.034
positive regulation of intracellular signal transduction GO:1902533 138 0.034
angiogenesis GO:0001525 53 0.034
lipid metabolic process GO:0006629 283 0.034
Rat
peptide transport GO:0015833 97 0.034
regulation of map kinase activity GO:0043405 53 0.034
Fly
negative regulation of metabolic process GO:0009892 331 0.034
Rat Fly
nucleoside triphosphate catabolic process GO:0009143 123 0.033
glial cell differentiation GO:0010001 65 0.033
heart morphogenesis GO:0003007 3 0.033
dna metabolic process GO:0006259 96 0.033
cardiac muscle tissue growth GO:0055017 20 0.033
positive regulation of secretion GO:0051047 140 0.032
Rat
positive regulation of response to stimulus GO:0048584 285 0.032
Mouse
peptide secretion GO:0002790 86 0.032
organ growth GO:0035265 24 0.032
response to toxic substance GO:0009636 133 0.032
Rat
regulation of synaptic transmission GO:0050804 141 0.031
response to peptide GO:1901652 292 0.031
ribonucleoside catabolic process GO:0042454 126 0.031
regulation of nucleotide metabolic process GO:0006140 117 0.031
positive regulation of nucleoside metabolic process GO:0045979 55 0.031
central nervous system development GO:0007417 311 0.031
Rat
neuronal action potential GO:0019228 35 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
protein complex biogenesis GO:0070271 263 0.030
organic substance catabolic process GO:1901575 316 0.030
negative regulation of gene expression GO:0010629 199 0.030
Rat
organ morphogenesis GO:0009887 75 0.030
Fly
positive regulation of ion transport GO:0043270 94 0.029
Rat
intracellular protein transport GO:0006886 79 0.029
Rat
nucleotide biosynthetic process GO:0009165 98 0.029
regulation of nervous system development GO:0051960 264 0.029
cell morphogenesis GO:0000902 142 0.029
Rat Fly
carbohydrate derivative catabolic process GO:1901136 147 0.029
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.028
ribonucleotide biosynthetic process GO:0009260 85 0.028
negative regulation of phosphate metabolic process GO:0045936 80 0.028
Fly
response to nutrient levels GO:0031667 370 0.028
purine containing compound biosynthetic process GO:0072522 85 0.028
protein targeting GO:0006605 61 0.028
Rat
nucleoside catabolic process GO:0009164 126 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
Rat Fly
regulation of nucleotide catabolic process GO:0030811 65 0.028
axis specification GO:0009798 4 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
Yeast Rat
intracellular transport GO:0046907 185 0.027
Rat
ribonucleoside monophosphate metabolic process GO:0009161 88 0.027
purine nucleotide catabolic process GO:0006195 136 0.027
positive regulation of cellular catabolic process GO:0031331 71 0.027
Fly
negative regulation of cellular metabolic process GO:0031324 281 0.027
Rat Fly
hormone metabolic process GO:0042445 69 0.027
dna replication GO:0006260 37 0.026
regulation of cell differentiation GO:0045595 320 0.026
Yeast Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.026
nucleotide catabolic process GO:0009166 139 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
response to other organism GO:0051707 220 0.026
Human Rat Fly
regulation of peptide transport GO:0090087 87 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.026
cellular protein localization GO:0034613 122 0.026
Rat
heart growth GO:0060419 20 0.025
macromolecule localization GO:0033036 252 0.025
Human Rat
localization of cell GO:0051674 202 0.025
regulation of fatty acid transport GO:2000191 10 0.025
Rat
hepaticobiliary system development GO:0061008 90 0.025
regulation of transcription dna templated GO:0006355 374 0.025
negative regulation of cell proliferation GO:0008285 119 0.025
monocarboxylic acid metabolic process GO:0032787 152 0.025
Rat
regulation of protein serine threonine kinase activity GO:0071900 64 0.025
Fly
negative regulation of nucleic acid templated transcription GO:1903507 117 0.025
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
positive regulation of mapk cascade GO:0043410 92 0.024
purine nucleotide biosynthetic process GO:0006164 83 0.024
insulin secretion GO:0030073 69 0.024
protein import into nucleus GO:0006606 35 0.024
organic acid transport GO:0015849 116 0.024
Rat
regulation of anatomical structure size GO:0090066 135 0.024
regulation of peptide hormone secretion GO:0090276 80 0.024
regulation of membrane potential GO:0042391 110 0.023
positive regulation of protein modification process GO:0031401 142 0.023
Rat
homeostatic process GO:0042592 331 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
negative regulation of synaptic transmission glutamatergic GO:0051967 8 0.023
regulation of blood circulation GO:1903522 110 0.023
enzyme linked receptor protein signaling pathway GO:0007167 116 0.023
cell cycle GO:0007049 101 0.023
Yeast Rat
regulation of apoptotic process GO:0042981 335 0.023
response to growth factor GO:0070848 189 0.023
Rat
response to transforming growth factor beta GO:0071559 46 0.023
amide transport GO:0042886 105 0.023
response to inorganic substance GO:0010035 377 0.023
regulation of catabolic process GO:0009894 113 0.022
Fly
protein localization to membrane GO:0072657 36 0.022
lipid biosynthetic process GO:0008610 128 0.022
Rat
blood circulation GO:0008015 183 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
cellular chemical homeostasis GO:0055082 247 0.022
regulation of peptide secretion GO:0002791 82 0.022
embryonic cranial skeleton morphogenesis GO:0048701 2 0.022
negative regulation of transcription dna templated GO:0045892 116 0.022
Rat
regulation of cellular catabolic process GO:0031329 101 0.021
Fly
negative regulation of phosphorus metabolic process GO:0010563 80 0.021
Fly
cellular response to organic cyclic compound GO:0071407 202 0.021
negative regulation of secretion GO:0051048 82 0.021
positive regulation of dna metabolic process GO:0051054 39 0.021
response to peptide hormone GO:0043434 278 0.021
positive regulation of gene expression GO:0010628 244 0.021
Human Yeast Rat
positive regulation of protein metabolic process GO:0051247 178 0.021
Rat
protein phosphorylation GO:0006468 345 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
response to insulin GO:0032868 133 0.020
positive regulation of blood circulation GO:1903524 65 0.020
regulation of synaptic transmission glutamatergic GO:0051966 26 0.020
multi organism reproductive process GO:0044703 262 0.020
Yeast Fly
organic cyclic compound catabolic process GO:1901361 175 0.020
protein oligomerization GO:0051259 191 0.020
sexual reproduction GO:0019953 148 0.020
Yeast Fly
circulatory system process GO:0003013 183 0.020
single organism catabolic process GO:0044712 283 0.020
response to monosaccharide GO:0034284 159 0.020
Rat
cellular response to growth factor stimulus GO:0071363 162 0.020
Rat
negative regulation of protein phosphorylation GO:0001933 44 0.020
Fly
regulation of kinase activity GO:0043549 117 0.020
Fly
organic acid biosynthetic process GO:0016053 83 0.020
Rat
cyclic nucleotide biosynthetic process GO:0009190 63 0.019
negative regulation of secretion by cell GO:1903531 72 0.019
regulation of cell proliferation GO:0042127 359 0.019
regulation of rna metabolic process GO:0051252 391 0.019
monocarboxylic acid transport GO:0015718 52 0.019
Rat
cell migration GO:0016477 197 0.019
response to acid chemical GO:0001101 222 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
Fly
cellular amine metabolic process GO:0044106 38 0.019
cellular response to peptide GO:1901653 133 0.019
aging GO:0007568 241 0.019
Worm
organic anion transport GO:0015711 132 0.019
Rat
nucleoside monophosphate metabolic process GO:0009123 93 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
Rat
negative regulation of apoptotic process GO:0043066 181 0.019
protein complex assembly GO:0006461 263 0.019
action potential GO:0001508 54 0.019
cyclic nucleotide metabolic process GO:0009187 80 0.018
regulation of ion transport GO:0043269 245 0.018
Rat
protein complex subunit organization GO:0071822 302 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
liver development GO:0001889 90 0.018
atp metabolic process GO:0046034 72 0.018
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
response to hexose GO:0009746 144 0.018
Rat
muscle tissue development GO:0060537 58 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
Rat
negative regulation of rna metabolic process GO:0051253 123 0.018
Rat
protein targeting to nucleus GO:0044744 35 0.018
neural crest cell differentiation GO:0014033 2 0.018
embryonic pattern specification GO:0009880 1 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
cellular response to external stimulus GO:0071496 118 0.017
Human
positive regulation of catalytic activity GO:0043085 184 0.017
Human Rat
oxoacid metabolic process GO:0043436 290 0.017
Rat
dephosphorylation GO:0016311 98 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
tissue development GO:0009888 252 0.017
Fly
gamete generation GO:0007276 124 0.017
Fly
cellular component movement GO:0006928 248 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
Yeast Rat
negative regulation of cell death GO:0060548 229 0.017
muscle structure development GO:0061061 87 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
negative regulation of transport GO:0051051 136 0.017
acid secretion GO:0046717 48 0.016
Rat
chemical homeostasis GO:0048878 292 0.016
amine metabolic process GO:0009308 38 0.016
response to mechanical stimulus GO:0009612 134 0.016
Human Rat
positive regulation of cell development GO:0010720 176 0.016
Rat
cellular response to metal ion GO:0071248 55 0.016
Fly
cellular response to nitrogen compound GO:1901699 210 0.016
Mouse
positive regulation of secretion by cell GO:1903532 128 0.016
muscle cell proliferation GO:0033002 84 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
response to fatty acid GO:0070542 65 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
Rat Fly
neuromuscular synaptic transmission GO:0007274 2 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.015
defense response GO:0006952 194 0.015
oxidation reduction process GO:0055114 304 0.015
response to glucose GO:0009749 136 0.015
Rat
heart development GO:0007507 72 0.015
regulation of gtpase activity GO:0043087 57 0.015
regulation of neurogenesis GO:0050767 247 0.015
cellular ketone metabolic process GO:0042180 51 0.015
Rat
prostaglandin transport GO:0015732 8 0.015
Rat
receptor mediated endocytosis GO:0006898 42 0.015
lipid storage GO:0019915 1 0.015
wound healing GO:0042060 122 0.015
Fly
cytosolic calcium ion homeostasis GO:0051480 140 0.015
response to fungicide GO:0060992 20 0.015
regulation of inflammatory response GO:0050727 48 0.015
ribose phosphate biosynthetic process GO:0046390 87 0.015
negative regulation of hormone secretion GO:0046888 46 0.015
release of cytochrome c from mitochondria GO:0001836 8 0.015
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.014
single organism behavior GO:0044708 130 0.014
positive regulation of fatty acid transport GO:2000193 9 0.014
Rat
head development GO:0060322 247 0.014
regulation of heart contraction GO:0008016 48 0.014
ossification GO:0001503 70 0.014
Mouse
blood vessel morphogenesis GO:0048514 58 0.014
negative regulation of cellular protein metabolic process GO:0032269 106 0.014
Fly
cytoplasmic transport GO:0016482 115 0.014
Rat
positive regulation of transcription dna templated GO:0045893 197 0.014
Yeast Rat
positive regulation of hydrolase activity GO:0051345 86 0.014
Human Rat
organ regeneration GO:0031100 101 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
cyclic purine nucleotide metabolic process GO:0052652 62 0.014
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
cellular response to alcohol GO:0097306 87 0.013
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.013
protein localization to organelle GO:0033365 57 0.013
Rat
regulation of blood pressure GO:0008217 83 0.013
lipid localization GO:0010876 62 0.013
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
positive regulation of leukocyte differentiation GO:1902107 13 0.013
cell motility GO:0048870 202 0.013
neuron apoptotic process GO:0051402 88 0.013
multicellular organism growth GO:0035264 1 0.013
phospholipid metabolic process GO:0006644 61 0.013
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.013
response to dexamethasone GO:0071548 49 0.013
cation transport GO:0006812 382 0.013
cellular homeostasis GO:0019725 252 0.013
rho protein signal transduction GO:0007266 11 0.013
myelination GO:0042552 39 0.013
regulation of jun kinase activity GO:0043506 10 0.013
Fly
purine containing compound catabolic process GO:0072523 138 0.013
single organism nuclear import GO:1902593 35 0.013
regulation of insulin secretion GO:0050796 65 0.013
positive regulation of transferase activity GO:0051347 81 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
striated muscle tissue development GO:0014706 58 0.013
response to oxidative stress GO:0006979 186 0.013
regulation of organelle organization GO:0033043 80 0.013
response to organophosphorus GO:0046683 102 0.012
halogenated hydrocarbon metabolic process GO:0042197 4 0.012
negative regulation of protein modification process GO:0031400 52 0.012
Fly
regulation of small gtpase mediated signal transduction GO:0051056 48 0.012
regulation of anion transport GO:0044070 43 0.012
Rat
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
transmembrane transport GO:0055085 412 0.012
axon development GO:0061564 96 0.012
Fly
regulation of transferase activity GO:0051338 123 0.012
Fly
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
positive regulation of catabolic process GO:0009896 78 0.012
Fly
protein tetramerization GO:0051262 38 0.012
nucleocytoplasmic transport GO:0006913 48 0.012
locomotor rhythm GO:0045475 1 0.012
feeding behavior GO:0007631 53 0.012
chemosensory behavior GO:0007635 2 0.012
response to temperature stimulus GO:0009266 94 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
Yeast
ribonucleoside monophosphate catabolic process GO:0009158 55 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
Rat
negative regulation of neurogenesis GO:0050768 78 0.012
regulation of cellular ketone metabolic process GO:0010565 27 0.012
Rat
heart process GO:0003015 57 0.012
atp catabolic process GO:0006200 54 0.012
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
regulation of response to wounding GO:1903034 69 0.012
macromolecular complex assembly GO:0065003 273 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
Fly
cellular response to inorganic substance GO:0071241 65 0.012
Mouse Fly
fatty acid transport GO:0015908 25 0.011
Rat
gtp metabolic process GO:0046039 72 0.011
protein import GO:0017038 37 0.011
dendrite development GO:0016358 72 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
Fly
microglial cell activation GO:0001774 14 0.011
epithelial cell differentiation GO:0030855 71 0.011
Fly
positive regulation of rna metabolic process GO:0051254 203 0.011
Yeast Rat
negative regulation of molecular function GO:0044092 133 0.011
Human Fly
positive regulation of icosanoid secretion GO:0032305 7 0.011
Rat
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
Rat

Mapk8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.012
organ system cancer DOID:0050686 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012