IMP

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Rattus norvegicus

19 genes annotated in rat

Multi-species View

regulation of jnk cascade

GO:0046328

Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of jnk cascade"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of jnk cascade" (in gray)

Name	Description	Probability	Func Analog Organism
Grip1	glutamate receptor interacting protein 1	0.535
Fkbp1a	FK506 binding protein 1a	0.370
Usf2	upstream transcription factor 2, c-fos interacting	0.296
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.283
Jtb	jumping translocation breakpoint	0.267
Mapk1	mitogen activated protein kinase 1	0.244
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.218
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.204
Ube2b	ubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)	0.190
Atp1b3	ATPase, Na+/K+ transporting, beta 3 polypeptide	0.156
Fgfr1	Fibroblast growth factor receptor 1	0.135
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.122
Sh3bp1	SH3-domain binding protein 1	0.115
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.113
Hsph1	heat shock 105/110 protein 1	0.111
Ccl4	chemokine (C-C motif) ligand 4	0.107
Grm7	glutamate receptor, metabotropic 7	0.105
LOC100364212	heterogeneous nuclear ribonucleoprotein K-like	0.093
Zhx1	zinc fingers and homeoboxes 1	0.087
Canx	calnexin	0.087
Gria2	glutamate receptor, ionotropic, AMPA 2	0.087	Rat
Mca32	mast cell antigen 32	0.085
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.084
Sf1	splicing factor 1	0.080
Cltc	clathrin, heavy chain (Hc)	0.078
Map2	microtubule-associated protein 2	0.076
Arl5a	ADP-ribosylation factor-like 5A	0.076
Ptp4a2	protein tyrosine phosphatase 4a2	0.075
Gria1	glutamate receptor, ionotropic, AMPA 1	0.074
Bcl2l2	Bcl2-like 2	0.071
Zfp36	zinc finger protein 36	0.067
Ube2a	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.067
Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	0.063
Pxn	paxillin	0.063
Mapk8	mitogen-activated protein kinase 8	0.061	Rat Fly
Myd88	myeloid differentiation primary response gene 88	0.058	Mouse
Itgam	integrin, alpha M	0.058
Jak1	Janus kinase 1	0.056
Map3k1	mitogen activated protein kinase kinase kinase 1	0.056
Nudt3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.055
Atf2	activating transcription factor 2	0.054
Col5a2	collagen, type V, alpha 2	0.054
Eef2	eukaryotic translation elongation factor 2	0.053
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.053
Elf1	E74-like factor 1	0.052
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.051
Prkacb	protein kinase, cAMP dependent, catalytic, beta	0.049
St13	suppression of tumorigenicity 13	0.048
Ptgs2	prostaglandin-endoperoxide synthase 2	0.047
Kcnk1	potassium channel, subfamily K, member 1	0.047
Prkcb	protein kinase C, beta	0.046	Rat
Rab10	RAB10, member RAS oncogene family	0.045
Gnrhr	gonadotropin releasing hormone receptor	0.044
Gltp	glycolipid transfer protein	0.043
Homer1	homer homolog 1 (Drosophila)	0.043
Itpr1	inositol 1,4,5-triphosphate receptor, type 1	0.043
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.042
Ccnl1	cyclin L1	0.041
Cttnbp2	cortactin binding protein 2	0.041
Fkbp4	FK506 binding protein 4	0.040
Il1b	interleukin 1 beta	0.038
Socs3	suppressor of cytokine signaling 3	0.038
Chordc1	cysteine and histidine-rich domain (CHORD)-containing 1	0.037
Dpp9	dipeptidyl peptidase 9	0.037
Tfeb	transcription factor EB	0.036
Gatad1	GATA zinc finger domain containing 1	0.036
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.035	Human
Cry2	cryptochrome 2 (photolyase-like)	0.035
Pdp1	pyruvate dehyrogenase phosphatase catalytic subunit 1	0.034
Rasgrp1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)	0.034
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.034
Tgfb2	transforming growth factor, beta 2	0.034
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.033
LOC286960	preprotrypsinogen IV	0.032
Adora2a	adenosine A2a receptor	0.032
Zfp706	zinc finger protein 706	0.032
Vegfa	vascular endothelial growth factor A	0.032
Il1r1	interleukin 1 receptor, type I	0.031
Ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.031
Mapk9	mitogen-activated protein kinase 9	0.031
Gria3	glutamate receptor, ionotrophic, AMPA 3	0.030	Rat
Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.030
Bap1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.029
Stat3	signal transducer and activator of transcription 3	0.029
Utrn	utrophin	0.028
Hist1h1a	histone cluster 1, H1a	0.028
Snrk	SNF related kinase	0.028
Eif5b	eukaryotic translation initiation factor 5B	0.028
RGD1305793	similar to hypothetical protein FLJ20154	0.028
Hspd1	heat shock protein 1 (chaperonin)	0.028
Plac8	placenta-specific 8	0.028
Dvl1	dishevelled, dsh homolog 1 (Drosophila)	0.028	Rat
Abcb4	ATP-binding cassette, subfamily B (MDR/TAP), member 4	0.028
March5	membrane-associated ring finger (C3HC4) 5	0.027
Oaz2	ornithine decarboxylase antizyme 2	0.027
Vat1	vesicle amine transport protein 1 homolog (T californica)	0.027
Plscr3	phospholipid scramblase 3	0.026
Akr1b7	aldo-keto reductase family 1, member B7	0.026
Ifit1	interferon-induced protein with tetratricopeptide repeats 1	0.026
Rybp	RING1 and YY1 binding protein	0.026
Syt2	synaptotagmin II	0.026
Cyp4a3	cytochrome P450, family 4, subfamily a, polypeptide 3	0.025
Vom1r101	vomeronasal 1 receptor 101	0.025
Nrcam	neuronal cell adhesion molecule	0.025
Parm1	prostate androgen-regulated mucin-like protein 1	0.025
Cd83	CD83 molecule	0.025
Gnai2	guanine nucleotide binding protein (G protein), alpha inhibiting 2	0.025
Pgr	progesterone receptor	0.025
Ppara	peroxisome proliferator activated receptor alpha	0.024
LOC100363783	rCG53773-like	0.024
Lrfn4	leucine rich repeat and fibronectin type III domain containing 4	0.024
Lphn3	latrophilin 3	0.024
Paqr5	progestin and adipoQ receptor family member V	0.024
Tff3	trefoil factor 3, intestinal	0.023
Acmsd	aminocarboxymuconate semialdehyde decarboxylase	0.023
Crispld2	cysteine-rich secretory protein LCCL domain containing 2	0.023
Phka1	phosphorylase kinase, alpha 1	0.022
Bmp6	bone morphogenetic protein 6	0.022
Lrp10	low-density lipoprotein receptor-related protein 10	0.022
Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	0.022
Fam126b	family with sequence similarity 126, member B	0.022
Hoxb13	homeo box B13	0.022
Map2k4	mitogen activated protein kinase kinase 4	0.021
Stip1	stress-induced phosphoprotein 1	0.021
Setd8-ps1	SET domain containing (lysine methyltransferase) 8, pseudogene 1	0.021
Dnahc6	dynein, axonemal, heavy chain 6	0.021
Ctnnd2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.021
Hspa8	heat shock protein 8	0.020
Rhd	Rh blood group, D antigen	0.020
Gsr	glutathione reductase	0.020
Cd40	CD40 molecule, TNF receptor superfamily member 5	0.020
Cugbp2	CUG triplet repeat, RNA binding protein 2	0.020
Cmtm6	CKLF-like MARVEL transmembrane domain containing 6	0.020
St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	0.019
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.019
Il1a	interleukin 1 alpha	0.019
Sema6b	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	0.019
Acer1	alkaline ceramidase 1	0.019
LOC683156	similar to testicular serine protease 2	0.018
Dctn4	dynactin 4	0.018
Rhog	ras homolog gene family, member G (rho G)	0.018	Rat
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.018
Slc30a4	solute carrier family 30 (zinc transporter), member 4	0.018
Tgm1	transglutaminase 1, K polypeptide	0.018
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.018
Gpc3	glypican 3	0.018
Gabra1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.018
Frmd8	FERM domain containing 8	0.018
Ier2	immediate early response 2	0.018
Lox	lysyl oxidase	0.018
Adamts1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.018
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.017
Slc39a1	solute carrier family 39 (zinc transporter), member 1	0.017
RT1-M5	RT1 class Ib, locus M5	0.017
Hck	hemopoietic cell kinase	0.017
Zcwpw1	zinc finger, CW-type with PWWP domain 1	0.017
Cdc34	cell division cycle 34 homolog (S. cerevisiae)	0.017
Pla2g10	phospholipase A2, group X	0.017
Csnk1g2	casein kinase 1, gamma 2	0.017
Rassf5	Ras association (RalGDS/AF-6) domain family member 5	0.017
Vcam1	vascular cell adhesion molecule 1	0.017
Dtx3l	deltex 3-like (Drosophila)	0.017
Pnlip	pancreatic lipase	0.017
Serinc1	serine incorporator 1	0.017
Wnt10a	wingless-type MMTV integration site family, member 10A	0.016	Rat
Cebpg	CCAAT/enhancer binding protein (C/EBP), gamma	0.016
Ckmt1	creatine kinase, mitochondrial 1	0.016
Svs1	seminal vesicle secretory protein 1	0.016
Pik3r2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.016
Nras	neuroblastoma ras oncogene	0.016
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.016
Tor1aip1	torsin A interacting protein 1	0.016
Birc3	baculoviral IAP repeat-containing 3	0.016
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.016
Mov10	Moloney leukemia virus 10	0.016
Tsc22d4	TSC22 domain family, member 4	0.016
Sgk1	serum/glucocorticoid regulated kinase 1	0.016
Vdac1	voltage-dependent anion channel 1	0.016
Me1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.016
Il1r2	interleukin 1 receptor, type II	0.016
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.016
Trh	thyrotropin releasing hormone	0.016
Ankrd13a	ankyrin repeat domain 13a	0.015
Ap3s1	adaptor-related protein complex 3, sigma 1 subunit	0.015
Batf3	basic leucine zipper transcription factor, ATF-like 3	0.015
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.015
LOC687797	similar to tumor suppressor candidate 5	0.015
Il2rg	interleukin 2 receptor, gamma	0.015
Pde5a	phosphodiesterase 5A, cGMP-specific	0.015
Epn1	Epsin 1	0.015
Tuba1a	tubulin, alpha 1A	0.015
Map3k7ip1	mitogen-activated protein kinase kinase kinase 7 interacting protein 1	0.015
Akap12	A kinase (PRKA) anchor protein 12	0.015
Aurkaip1	aurora kinase A interacting protein 1	0.015
Nxn	nucleoredoxin	0.015
Chp	calcium binding protein p22	0.015
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.015
Tnfrsf11a	Tumor necrosis factor receptor superfamily, member 11a	0.015
Tmed5	transmembrane emp24 protein transport domain containing 5	0.015
Mll4	myeloid/lymphoid or mixed-lineage leukemia 4	0.015
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.015
Akt1s1	AKT1 substrate 1 (proline-rich)	0.015
Dbh	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	0.015
Map3k7ip2	mitogen-activated protein kinase kinase kinase 7 interacting protein 2	0.015
Akap1	A kinase (PRKA) anchor protein 1	0.014
Ptk2b	PTK2B protein tyrosine kinase 2 beta	0.014
Coro1b	coronin, actin-binding protein, 1B	0.014
Capn8	calpain 8	0.014
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.014	Fly
Gnb4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.014
RGD1308722	similar to RIKEN cDNA A130042E20; open reading frame 57	0.014
Clcn4-2	chloride channel 4-2	0.014
Mapk8ip1	mitogen-activated protein kinase 8 interacting protein 1	0.014
Blvra	biliverdin reductase A	0.014
Smox	spermine oxidase	0.014
Thbd	thrombomodulin	0.014
Grin2d	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.014
Mapkapk2	mitogen-activated protein kinase-activated protein kinase 2	0.014
Ppard	peroxisome proliferator-activated receptor delta	0.014
Grm3	glutamate receptor, metabotropic 3	0.014
Bspry	B-box and SPRY domain containing	0.014
Rab14	RAB14, member RAS oncogene family	0.014
Fbxo2	F-box protein 2	0.014
Il6	interleukin 6	0.014
Fam180a	family with sequence similarity 180, member A	0.013
Ptprk	protein tyrosine phosphatase, receptor type, K, extracellular region	0.013
Ggn	gametogenetin	0.013
Hspa1a	heat shock 70kD protein 1A	0.013
Klf9	Kruppel-like factor 9	0.013
Il2ra	interleukin 2 receptor, alpha	0.013
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.013
Fchsd1	FCH and double SH3 domains 1	0.013
Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	0.013
Ssfa2	sperm specific antigen 2	0.013
Laptm5	lysosomal protein transmembrane 5	0.013
Klf6	Kruppel-like factor 6	0.013
Slit3	slit homolog 3 (Drosophila)	0.013
Lce1f	late cornified envelope 1F	0.013
Prss2	protease, serine, 2	0.013
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.013
F2rl2	coagulation factor II (thrombin) receptor-like 2	0.013
Akt1	v-akt murine thymoma viral oncogene homolog 1	0.013
Inpp5d	inositol polyphosphate-5-phosphatase D	0.013
Dlg3	discs, large homolog 3 (Drosophila)	0.013
Cilp2	cartilage intermediate layer protein 2	0.013
Jun	Jun oncogene	0.013
Tob2	transducer of ERBB2, 2	0.013
Gja1	gap junction protein, alpha 1	0.013
Rbm38	RNA binding motif protein 38	0.013
Dusp7	dual specificity phosphatase 7	0.013
Abcg5	ATP-binding cassette, subfamily G (WHITE), member 5	0.013
Git1	G protein-coupled receptor kinase interacting ArfGAP 1	0.013
Rab1b	RAB1B, member RAS oncogene family	0.013
Prkg2	protein kinase, cGMP-dependent, type II	0.012
Farp1	FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)	0.012
Vegfb	vascular endothelial growth factor B	0.012
Cntfr	ciliary neurotrophic factor receptor	0.012
Psp	parotid secretory protein	0.012
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.012
S1pr2	sphingosine-1-phosphate receptor 2	0.012
Arrdc1	arrestin domain containing 1	0.012
Fam69b	family with sequence similarity 69, member B	0.012
Ier3	immediate early response 3	0.012
Mgea5	meningioma expressed antigen 5 (hyaluronidase)	0.012
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.012
Kidins220	kinase D-interacting substrate 220	0.012
Mapk3	mitogen activated protein kinase 3	0.012
Slc25a21	solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21	0.012
Dnajc3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.012
Axin1	axin 1	0.012	Mouse
Gja3	gap junction protein, alpha 3	0.012
Cyp11a1	cytochrome P450, family 11, subfamily a, polypeptide 1	0.012
Hras	Harvey rat sarcoma virus oncogene	0.012	Human
Orai1	ORAI calcium release-activated calcium modulator 1	0.012
Gna15	guanine nucleotide binding protein, alpha 15	0.012
Rgs12	regulator of G-protein signaling 12	0.012
LOC100363700	probable N-acetyltransferase CML4-like	0.012
RGD1309414	similar to KIAA0913 protein	0.012
Ttn	titin	0.012
Ccdc92	coiled-coil domain containing 92	0.012
Sec63	SEC63 homolog (S. cerevisiae)	0.012
Pcyox1	prenylcysteine oxidase 1	0.012
Macf1	microtubule-actin crosslinking factor 1	0.012
Sod2	superoxide dismutase 2, mitochondrial	0.012
Scube1	signal peptide, CUB domain, EGF-like 1	0.012
Clcn3	chloride channel 3	0.012
Raf1	v-raf-leukemia viral oncogene 1	0.012
Dnajc5	DnaJ (Hsp40) homolog, subfamily C, member 5	0.012
Senp2	Sumo1/sentrin/SMT3 specific peptidase 2	0.012
Nfkbie	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.012
Col4a3bp	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.011
Pyy	peptide YY (mapped)	0.011
Pick1	protein interacting with PRKCA 1	0.011
Gls2	glutaminase 2 (liver, mitochondrial)	0.011
Csdc2	cold shock domain containing C2, RNA binding	0.011
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.011
Plk5	polo-like kinase 5	0.011
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.011
Nrd1	nardilysin 1	0.011
Spag9	sperm associated antigen 9	0.011
Ece1	endothelin converting enzyme 1	0.011
Tpm1	tropomyosin 1, alpha	0.011
Rala	v-ral simian leukemia viral oncogene homolog A (ras related)	0.011	Fly
Boc	biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein	0.011
Gtf2a1	general transcription factor IIA, 1	0.011
Syt4	synaptotagmin IV	0.011
F2r	coagulation factor II (thrombin) receptor	0.011
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.011
Gpr4	G protein-coupled receptor 4	0.011
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.011
Gnai1	guanine nucleotide binding protein (G protein), alpha inhibiting 1	0.011
Ceacam10	carcinoembryonic antigen-related cell adhesion molecule 10	0.011
Vamp1	vesicle-associated membrane protein 1	0.011
Znf532	zinc finger protein 532	0.011
Zc3h12a	zinc finger CCCH type containing 12A	0.011
Tbx3	T-box 3	0.011
Akap2	A kinase (PRKA) anchor protein 2	0.011
Amfr	autocrine motility factor receptor	0.011
Pgm2	phosphoglucomutase 2	0.011
Fkbp3	FK506 binding protein 3	0.011
Grn	granulin	0.011
Sdcbp2	syndecan binding protein (syntenin) 2	0.011
Syngr2	synaptogyrin 2	0.011
Ednrb	endothelin receptor type B	0.010
Epas1	endothelial PAS domain protein 1	0.010
Ptar1	protein prenyltransferase alpha subunit repeat containing 1	0.010
Ndel1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.010
Cdc42	cell division cycle 42 (GTP binding protein)	0.010
Galnt2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	0.010
Arhgap17	Rho GTPase activating protein 17	0.010
Icam1	intercellular adhesion molecule 1	0.010
Ppid	peptidylprolyl isomerase D (cyclophilin D)	0.010
Vcan	versican	0.010
Otx1	orthodenticle homeobox 1	0.010
Mdfic	MyoD family inhibitor domain containing	0.010
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.010
Dbp	D site of albumin promoter (albumin D-box) binding protein	0.010
Gabra2	gamma-aminobutyric acid (GABA-A) receptor, subunit alpha 2	0.010