Rattus norvegicus

19 known processes

Mmp12

matrix metallopeptidase 12

(Aliases: Mme)

Mmp12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.844
immune response GO:0006955 104 0.837
response to tumor necrosis factor GO:0034612 56 0.808
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.786
Rat
immune system process GO:0002376 204 0.718
Rat
cellular response to lipoteichoic acid GO:0071223 1 0.685
anatomical structure morphogenesis GO:0009653 298 0.685
Rat
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.651
defense response GO:0006952 194 0.605
cell adhesion GO:0007155 110 0.583
Rat
regulation of immune system process GO:0002682 123 0.578
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.545
Rat
cellular response to cytokine stimulus GO:0071345 127 0.540
Rat
regulation of multicellular organismal development GO:2000026 376 0.507
Rat
regulation of natural killer cell mediated immunity GO:0002715 6 0.493
cellular response to endogenous stimulus GO:0071495 377 0.487
Rat
innate immune response GO:0045087 35 0.479
cellular component movement GO:0006928 248 0.476
Rat
cellular response to molecule of bacterial origin GO:0071219 56 0.441
Rat
positive regulation of fever generation GO:0031622 5 0.438
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.436
Rat
locomotion GO:0040011 237 0.429
Rat
cellular response to lipopolysaccharide GO:0071222 55 0.424
Rat
regulation of behavior GO:0050795 61 0.419
cellular response to oxygen containing compound GO:1901701 386 0.412
Rat
cellular response to lipid GO:0071396 201 0.390
Rat
neuron development GO:0048666 286 0.389
Rat
cellular response to biotic stimulus GO:0071216 59 0.387
Rat
biological adhesion GO:0022610 110 0.386
Rat
positive regulation of response to stimulus GO:0048584 285 0.385
homeostatic process GO:0042592 331 0.381
cellular response to alkaloid GO:0071312 25 0.353
Rat
cellular response to nitrogen compound GO:1901699 210 0.349
Rat
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.347
eosinophil chemotaxis GO:0048245 3 0.343
negative regulation of innate immune response GO:0045824 4 0.341
regulation of cellular component movement GO:0051270 150 0.338
Rat
regulation of phosphate metabolic process GO:0019220 349 0.332
response to peptide GO:1901652 292 0.332
Rat
response to inorganic substance GO:0010035 377 0.332
Rat
response to radiation GO:0009314 137 0.326
Rat
response to other organism GO:0051707 220 0.318
Rat
positive regulation of cell motility GO:2000147 97 0.314
Rat
regulation of phosphorylation GO:0042325 248 0.307
positive regulation of cellular biosynthetic process GO:0031328 295 0.302
negative regulation of immune response to tumor cell GO:0002838 2 0.302
response to low density lipoprotein particle GO:0055098 4 0.297
Rat
cellular response to organonitrogen compound GO:0071417 197 0.297
Rat
cellular response to organic cyclic compound GO:0071407 202 0.292
Rat
cell motility GO:0048870 202 0.292
Rat
negative regulation of response to tumor cell GO:0002835 2 0.291
neuron apoptotic process GO:0051402 88 0.284
response to external biotic stimulus GO:0043207 221 0.281
Rat
regulation of cell development GO:0060284 263 0.270
cellular response to iron iii ion GO:0071283 3 0.269
Rat
response to estradiol GO:0032355 164 0.268
Rat
regulation of anatomical structure size GO:0090066 135 0.268
Rat
response to mechanical stimulus GO:0009612 134 0.267
Rat
t cell chemotaxis GO:0010818 2 0.267
leukocyte activation GO:0045321 76 0.266
response to purine containing compound GO:0014074 126 0.261
Rat
response to corticosteroid GO:0031960 235 0.258
response to cytokine GO:0034097 215 0.258
Rat
positive regulation of immune system process GO:0002684 90 0.254
Rat
regulation of molecular function GO:0065009 398 0.251
regulation of cell killing GO:0031341 12 0.238
cellular response to external stimulus GO:0071496 118 0.237
Rat
positive regulation of transport GO:0051050 245 0.235
intracellular signal transduction GO:0035556 314 0.229
cell projection organization GO:0030030 302 0.227
Rat
regulation of neurogenesis GO:0050767 247 0.227
regulation of nervous system development GO:0051960 264 0.226
establishment of synaptic specificity at neuromuscular junction GO:0007529 1 0.224
regulation of lymphocyte chemotaxis GO:1901623 1 0.222
response to estrogen GO:0043627 232 0.221
Rat
regulation of immune response GO:0050776 55 0.218
positive regulation of developmental process GO:0051094 283 0.216
Rat
cellular response to hormone stimulus GO:0032870 247 0.216
Rat
negative regulation of cell death GO:0060548 229 0.213
regulation of immune response to tumor cell GO:0002837 3 0.212
regulation of fever generation GO:0031620 6 0.209
regulation of locomotion GO:0040012 148 0.205
Rat
blood circulation GO:0008015 183 0.202
Rat
protein complex subunit organization GO:0071822 302 0.201
Rat
acute phase response GO:0006953 20 0.200
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.198
regulation of cellular component organization GO:0051128 368 0.198
response to temperature stimulus GO:0009266 94 0.197
Rat
response to biotic stimulus GO:0009607 226 0.197
Rat
cellular calcium ion homeostasis GO:0006874 160 0.193
establishment of protein localization GO:0045184 141 0.192
positive regulation of cell communication GO:0010647 271 0.191
response to amino acid GO:0043200 75 0.189
Rat
positive regulation of programmed cell death GO:0043068 157 0.187
Rat
chemical homeostasis GO:0048878 292 0.186
cellular response to tumor necrosis factor GO:0071356 46 0.178
Rat
neuron death GO:0070997 127 0.178
response to nutrient GO:0007584 248 0.171
Rat
response to extracellular stimulus GO:0009991 380 0.170
Rat
metal ion homeostasis GO:0055065 186 0.170
regulation of system process GO:0044057 208 0.168
Rat
regulation of cytokine production GO:0001817 56 0.167
response to lipopolysaccharide GO:0032496 191 0.166
Rat
protein complex assembly GO:0006461 263 0.166
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.165
cellular response to peptide hormone stimulus GO:0071375 120 0.165
Rat
positive regulation of signaling GO:0023056 270 0.164
cellular response to peptide GO:1901653 133 0.163
Rat
response to hydrogen peroxide GO:0042542 89 0.160
Rat
response to peptide hormone GO:0043434 278 0.157
Rat
cellular response to lipoprotein particle stimulus GO:0071402 5 0.155
Rat
cell activation GO:0001775 97 0.152
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.151
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.151
cellular component assembly GO:0022607 360 0.147
Rat
response to interleukin 1 GO:0070555 55 0.146
Rat
response to reactive oxygen species GO:0000302 120 0.146
Rat
negative regulation of response to stimulus GO:0048585 155 0.145
regulation of t cell migration GO:2000404 1 0.145
cytokine production GO:0001816 61 0.144
response to glucocorticoid GO:0051384 223 0.143
cellular cation homeostasis GO:0030003 180 0.142
regulation of t cell chemotaxis GO:0010819 1 0.141
rna metabolic process GO:0016070 406 0.140
interleukin 1 biosynthetic process GO:0042222 1 0.140
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.140
leukocyte activation involved in immune response GO:0002366 16 0.139
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.139
response to oxidative stress GO:0006979 186 0.138
Rat
cellular component biogenesis GO:0044085 368 0.137
Rat
response to vitamin GO:0033273 131 0.137
Rat
cellular response to interleukin 1 GO:0071347 37 0.135
Rat
neuron projection development GO:0031175 273 0.135
Rat
macromolecule localization GO:0033036 252 0.135
cellular metal ion homeostasis GO:0006875 172 0.135
cd8 positive alpha beta t cell extravasation GO:0035697 0 0.133
hindlimb morphogenesis GO:0035137 2 0.132
Rat
positive regulation of synaptic plasticity GO:0031915 3 0.131
Rat
secretion by cell GO:0032940 248 0.131
positive regulation of gene expression GO:0010628 244 0.131
wound healing GO:0042060 122 0.131
Rat
leukocyte migration GO:0050900 38 0.131
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.131
regulation of cellular protein metabolic process GO:0032268 267 0.130
response to tumor cell GO:0002347 4 0.128
response to bacterium GO:0009617 200 0.127
Rat
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002858 1 0.125
regulation of intracellular signal transduction GO:1902531 218 0.124
regulation of natural killer cell mediated cytotoxicity GO:0042269 6 0.124
regulation of cell differentiation GO:0045595 320 0.122
response to alkyl hydroperoxide GO:0033195 1 0.122
negative regulation of multicellular organismal process GO:0051241 203 0.122
Rat
response to virus GO:0009615 17 0.120
eosinophil migration GO:0072677 3 0.120
response to growth factor GO:0070848 189 0.118
angiogenesis GO:0001525 53 0.118
Rat
cellular response to stress GO:0033554 269 0.117
Rat
neuron differentiation GO:0030182 368 0.116
Rat
regulation of tube size GO:0035150 89 0.115
Rat
signal transduction by phosphorylation GO:0023014 144 0.114
t helper 1 cell extravasation GO:0035687 1 0.113
protein transport GO:0015031 132 0.113
regulation of cell projection organization GO:0031344 175 0.112
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.110
regulation of signal transduction GO:0009966 318 0.110
cellular chemical homeostasis GO:0055082 247 0.110
response to high density lipoprotein particle GO:0055099 2 0.109
negative regulation of cellular metabolic process GO:0031324 281 0.108
regulation of leukocyte migration GO:0002685 24 0.108
Rat
rna biosynthetic process GO:0032774 380 0.107
apoptotic process GO:0006915 381 0.107
Rat
cytoskeleton organization GO:0007010 111 0.107
regulation of innate immune response GO:0045088 15 0.106
response to acid chemical GO:0001101 222 0.106
Rat
response to molecule of bacterial origin GO:0002237 194 0.106
Rat
response to heat GO:0009408 60 0.105
Rat
positive regulation of cell differentiation GO:0045597 217 0.104
regulation of neuron differentiation GO:0045664 208 0.103
positive regulation of apoptotic process GO:0043065 154 0.102
Rat
cellular response to hydroperoxide GO:0071447 2 0.101
divalent inorganic cation homeostasis GO:0072507 165 0.101
regulation of neuron death GO:1901214 115 0.099
cellular response to ketone GO:1901655 51 0.099
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.098
response to organophosphorus GO:0046683 102 0.098
Rat
regulation of protein metabolic process GO:0051246 289 0.097
positive regulation of phosphate metabolic process GO:0045937 262 0.097
ion homeostasis GO:0050801 212 0.097
response to alkaloid GO:0043279 132 0.096
Rat
negative regulation of defense response GO:0031348 19 0.095
positive regulation of behavior GO:0048520 38 0.095
positive regulation of lymphocyte migration GO:2000403 1 0.094
positive regulation of neurogenesis GO:0050769 165 0.094
response to metal ion GO:0010038 253 0.094
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.093
cellular response to alcohol GO:0097306 87 0.093
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.092
response to vitamin d GO:0033280 34 0.092
Rat
negative regulation of neuron death GO:1901215 69 0.091
positive regulation of phosphorylation GO:0042327 177 0.091
protein localization GO:0008104 191 0.091
protein phosphorylation GO:0006468 345 0.090
immune effector process GO:0002252 53 0.089
tissue development GO:0009888 252 0.089
Rat
response to nutrient levels GO:0031667 370 0.089
Rat
inflammatory response GO:0006954 150 0.088
cellular homeostasis GO:0019725 252 0.088
regulation of response to stress GO:0080134 126 0.085
response to light stimulus GO:0009416 52 0.085
Rat
regulation of interleukin 6 production GO:0032675 12 0.085
leukocyte cell cell adhesion GO:0007159 4 0.084
positive regulation of cell development GO:0010720 176 0.084
positive regulation of t cell migration GO:2000406 1 0.084
regulation of cell motility GO:2000145 131 0.083
Rat
positive regulation of molecular function GO:0044093 230 0.081
leukocyte degranulation GO:0043299 12 0.081
positive regulation of tumor necrosis factor production GO:0032760 8 0.081
carbohydrate metabolic process GO:0005975 130 0.081
fever generation GO:0001660 9 0.081
positive regulation of phosphorus metabolic process GO:0010562 262 0.080
multi multicellular organism process GO:0044706 138 0.080
Rat
regulation of rna biosynthetic process GO:2001141 381 0.079
response to interferon gamma GO:0034341 20 0.079
positive regulation of cell migration GO:0030335 96 0.078
Rat
t cell tolerance induction GO:0002517 3 0.077
positive regulation of nervous system development GO:0051962 178 0.077
cation homeostasis GO:0055080 195 0.077
regulation of rna metabolic process GO:0051252 391 0.076
programmed cell death GO:0012501 392 0.076
Rat
cell type specific apoptotic process GO:0097285 134 0.076
positive regulation of nucleic acid templated transcription GO:1903508 197 0.076
single organism intracellular transport GO:1902582 166 0.075
cellular component morphogenesis GO:0032989 155 0.074
regulation of chemotaxis GO:0050920 29 0.074
calcium ion homeostasis GO:0055074 162 0.073
dibenzo p dioxin metabolic process GO:0018894 10 0.073
cellular response to vitamin k GO:0071307 1 0.072
positive regulation of protein phosphorylation GO:0001934 135 0.070
cytokine biosynthetic process GO:0042089 3 0.070
growth GO:0040007 165 0.069
myeloid leukocyte activation GO:0002274 36 0.069
regulation of defense response GO:0031347 68 0.069
cellular ion homeostasis GO:0006873 184 0.069
positive regulation of interleukin 1 biosynthetic process GO:0045362 1 0.069
carbohydrate derivative metabolic process GO:1901135 346 0.069
cellular response to oxidative stress GO:0034599 76 0.069
regulation of establishment of protein localization GO:0070201 69 0.069
cellular response to nutrient levels GO:0031669 60 0.068
Rat
aging GO:0007568 241 0.067
Rat
negative regulation of immune response GO:0050777 15 0.067
g protein coupled receptor signaling pathway GO:0007186 242 0.066
positive regulation of cellular component movement GO:0051272 102 0.066
Rat
immune response to tumor cell GO:0002418 3 0.066
regulation of response to tumor cell GO:0002834 3 0.066
regulation of protein modification process GO:0031399 194 0.066
response to ketone GO:1901654 182 0.065
peptide biosynthetic process GO:0043043 3 0.065
response to iron iii ion GO:0010041 6 0.064
Rat
negative regulation of chronic inflammatory response GO:0002677 2 0.064
transcription dna templated GO:0006351 377 0.064
chemotaxis GO:0006935 66 0.063
regulation of response to external stimulus GO:0032101 106 0.063
positive regulation of interleukin 1 alpha biosynthetic process GO:0050726 1 0.063
mast cell migration GO:0097531 4 0.063
positive regulation of signal transduction GO:0009967 175 0.063
reactive nitrogen species metabolic process GO:2001057 1 0.063
catabolic process GO:0009056 351 0.062
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.062
response to hypoxia GO:0001666 231 0.062
Rat
smooth muscle cell migration GO:0014909 36 0.062
Rat
circulatory system process GO:0003013 183 0.061
Rat
reproductive process GO:0022414 372 0.061
Rat
response to transforming growth factor beta GO:0071559 46 0.061
positive regulation of biosynthetic process GO:0009891 319 0.060
positive regulation of mapk cascade GO:0043410 92 0.060
positive regulation of cytokine production GO:0001819 42 0.060
carboxylic acid metabolic process GO:0019752 289 0.059
positive regulation of cytokine biosynthetic process GO:0042108 1 0.059
negative regulation of developmental process GO:0051093 125 0.059
neuron projection morphogenesis GO:0048812 122 0.059
neurological system process GO:0050877 219 0.059
localization of cell GO:0051674 202 0.058
Rat
microglial cell activation GO:0001774 14 0.058
regulation of mast cell chemotaxis GO:0060753 1 0.058
positive regulation of locomotion GO:0040017 102 0.057
Rat
positive regulation of chemotaxis GO:0050921 23 0.057
myeloid leukocyte migration GO:0097529 20 0.057
leukocyte mediated immunity GO:0002443 28 0.057
cell projection morphogenesis GO:0048858 123 0.057
protein secretion GO:0009306 34 0.057
cellular amine metabolic process GO:0044106 38 0.057
positive regulation of smooth muscle cell migration GO:0014911 27 0.057
Rat
response to mineralocorticoid GO:0051385 49 0.056
reactive oxygen species metabolic process GO:0072593 37 0.056
response to camp GO:0051591 91 0.056
Rat
single organism cell adhesion GO:0098602 46 0.055
cytosolic calcium ion homeostasis GO:0051480 140 0.055
negative regulation of immune system process GO:0002683 39 0.054
positive regulation of cell death GO:0010942 184 0.054
Rat
nucleic acid templated transcription GO:0097659 379 0.054
cytosolic calcium ion transport GO:0060401 39 0.053
sensory perception of pain GO:0019233 73 0.053
positive regulation of secretion by cell GO:1903532 128 0.053
positive regulation of cellular amine metabolic process GO:0033240 3 0.053
axonogenesis GO:0007409 71 0.052
granulocyte chemotaxis GO:0071621 15 0.052
regulation of secretion GO:0051046 224 0.052
actin cytoskeleton organization GO:0030036 73 0.052
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 8 0.052
behavior GO:0007610 205 0.052
natural killer cell mediated immunity GO:0002228 6 0.051
regeneration GO:0031099 163 0.051
Rat
organelle organization GO:0006996 266 0.051
blood vessel morphogenesis GO:0048514 58 0.051
Rat
multicellular organismal reproductive process GO:0048609 233 0.051
Rat
response to oxygen levels GO:0070482 265 0.051
Rat
response to lipoprotein particle GO:0055094 8 0.051
Rat
organophosphate metabolic process GO:0019637 370 0.050
negative regulation of biosynthetic process GO:0009890 168 0.050
positive regulation of protein modification process GO:0031401 142 0.050
cellular response to growth factor stimulus GO:0071363 162 0.050
leukocyte chemotaxis GO:0030595 22 0.050
hormone secretion GO:0046879 115 0.050
reproduction GO:0000003 245 0.050
Rat
lymphocyte activation GO:0046649 43 0.050
response to toxic substance GO:0009636 133 0.050
regulation of cellular localization GO:0060341 263 0.049
temperature homeostasis GO:0001659 17 0.049
regulation of interleukin 1 production GO:0032652 11 0.049
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.048
regulation of cytokine biosynthetic process GO:0042035 3 0.048
regulation of cell proliferation GO:0042127 359 0.047
cellular ketone metabolic process GO:0042180 51 0.047
multi organism reproductive process GO:0044703 262 0.047
Rat
developmental process involved in reproduction GO:0003006 159 0.047
Rat
positive regulation of leukocyte migration GO:0002687 21 0.047
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.047
muscle structure development GO:0061061 87 0.047
positive regulation of protein metabolic process GO:0051247 178 0.046
vesicle mediated transport GO:0016192 181 0.046
Rat
response to monosaccharide GO:0034284 159 0.046
anatomical structure formation involved in morphogenesis GO:0048646 83 0.046
Rat
developmental growth GO:0048589 100 0.046
negative regulation of response to external stimulus GO:0032102 37 0.046
positive regulation of cell proliferation GO:0008284 249 0.046
t cell migration GO:0072678 2 0.046
regulation of growth GO:0040008 105 0.045
response to wounding GO:0009611 254 0.045
Rat
muscle contraction GO:0006936 88 0.045
response to indole 3 methanol GO:0071680 2 0.045
Rat
cellular response to alkyl hydroperoxide GO:0071448 1 0.044
response to insulin GO:0032868 133 0.044
regulation of neuron projection development GO:0010975 161 0.044
macromolecular complex subunit organization GO:0043933 339 0.043
Rat
protein oligomerization GO:0051259 191 0.043
Rat
mast cell chemotaxis GO:0002551 4 0.043
regulation of apoptotic process GO:0042981 335 0.042
Rat
cell part morphogenesis GO:0032990 123 0.042
nucleoside phosphate metabolic process GO:0006753 283 0.042
mapk cascade GO:0000165 140 0.042
regulation of dna metabolic process GO:0051052 60 0.042
positive regulation of neuron projection development GO:0010976 99 0.042
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.041
cellular response to ethanol GO:0071361 13 0.041
nitrogen compound transport GO:0071705 229 0.041
vascular process in circulatory system GO:0003018 96 0.041
Rat
regulation of cell migration GO:0030334 128 0.041
Rat
lipid metabolic process GO:0006629 283 0.041
cell cell signaling GO:0007267 335 0.040
Rat
regulation of transferase activity GO:0051338 123 0.040
regulation of programmed cell death GO:0043067 341 0.040
Rat
regulation of ion transport GO:0043269 245 0.040
pattern recognition receptor signaling pathway GO:0002221 9 0.040
taxis GO:0042330 67 0.040
macromolecular complex assembly GO:0065003 273 0.040
Rat
actin filament based process GO:0030029 86 0.040
lymphocyte chemotaxis GO:0048247 3 0.040
response to electrical stimulus GO:0051602 56 0.039
Rat
interleukin 1 alpha production GO:0032610 1 0.039
sex differentiation GO:0007548 113 0.039
Rat
response to interleukin 13 GO:0035962 3 0.039
negative regulation of nervous system development GO:0051961 79 0.039
cellular response to metal ion GO:0071248 55 0.039
Rat
reactive oxygen species biosynthetic process GO:1903409 8 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
calcium ion transport into cytosol GO:0060402 38 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
negative regulation of cellular biosynthetic process GO:0031327 161 0.038
peptidyl amino acid modification GO:0018193 126 0.038
regulation of response to wounding GO:1903034 69 0.038
positive regulation of secretion GO:0051047 140 0.038
multicellular organismal catabolic process GO:0044243 2 0.038
Rat
sequestering of calcium ion GO:0051208 8 0.038
cellular response to fluid shear stress GO:0071498 4 0.038
Rat
positive regulation of rna metabolic process GO:0051254 203 0.038
response to fluid shear stress GO:0034405 16 0.038
Rat
positive regulation of ion transport GO:0043270 94 0.038
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.037
regulation of catalytic activity GO:0050790 304 0.037
response to lipoteichoic acid GO:0070391 1 0.037
muscle system process GO:0003012 115 0.037
hexose metabolic process GO:0019318 58 0.037
natural killer cell mediated cytotoxicity GO:0042267 6 0.037
positive regulation of neuron differentiation GO:0045666 126 0.037
intracellular transport GO:0046907 185 0.037
amine metabolic process GO:0009308 38 0.036
regulation of cytokine secretion GO:0050707 11 0.036
regulation of smooth muscle contraction GO:0006940 29 0.036
muscle cell migration GO:0014812 36 0.036
Rat
cellular response to acid chemical GO:0071229 75 0.036
negative regulation of cell killing GO:0031342 5 0.036
cellular response to mechanical stimulus GO:0071260 48 0.035
transformation of host cell by virus GO:0019087 4 0.035
Rat
organic substance catabolic process GO:1901575 316 0.035
Rat
tube development GO:0035295 89 0.035
regulation of hydrolase activity GO:0051336 143 0.035
response to gamma radiation GO:0010332 24 0.035
b cell activation involved in immune response GO:0002312 1 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
sensory perception GO:0007600 101 0.035
response to fatty acid GO:0070542 65 0.034
pseudopodium organization GO:0031268 3 0.034
regulation of leukocyte mediated cytotoxicity GO:0001910 10 0.034
cellular response to extracellular stimulus GO:0031668 73 0.034
Rat
regulation of cellular response to stress GO:0080135 49 0.034
cellular catabolic process GO:0044248 295 0.034
Rat
glycosyl compound catabolic process GO:1901658 126 0.034
cellular response to high density lipoprotein particle stimulus GO:0071403 2 0.033
luteolysis GO:0001554 5 0.033
Rat
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.033
regulation of membrane potential GO:0042391 110 0.033
negative regulation of leukocyte mediated immunity GO:0002704 6 0.033
female gonad development GO:0008585 53 0.033
Rat
sequestering of metal ion GO:0051238 9 0.033
regulation of renin secretion into blood stream GO:1900133 1 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.032
pseudopodium assembly GO:0031269 3 0.032
single organism biosynthetic process GO:0044711 342 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
response to transition metal nanoparticle GO:1990267 122 0.032
Rat
regulation of neuron apoptotic process GO:0043523 83 0.032
positive regulation of transcription factor import into nucleus GO:0042993 4 0.032
amide biosynthetic process GO:0043604 10 0.031
response to ionizing radiation GO:0010212 59 0.031
regulation of interleukin 1 biosynthetic process GO:0045360 1 0.031
positive regulation of response to external stimulus GO:0032103 51 0.031
histamine secretion involved in inflammatory response GO:0002441 3 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.030
regulation of kinase activity GO:0043549 117 0.030
positive regulation of homeostatic process GO:0032846 49 0.030
positive regulation of rna biosynthetic process GO:1902680 197 0.030
positive regulation of t cell chemotaxis GO:0010820 1 0.030
regulation of muscle contraction GO:0006937 53 0.030
negative regulation of neuron apoptotic process GO:0043524 45 0.030
positive regulation of muscle contraction GO:0045933 22 0.030
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.030
regulation of immune effector process GO:0002697 32 0.030
immune response activating signal transduction GO:0002757 15 0.030
regulation of mapk cascade GO:0043408 116 0.029
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.029
divalent inorganic cation transport GO:0072511 134 0.029
divalent metal ion transport GO:0070838 132 0.029
positive regulation of angiogenesis GO:0045766 28 0.029
Rat
synapse organization GO:0050808 46 0.029
reproductive structure development GO:0048608 128 0.029
Rat
regulation of transcription dna templated GO:0006355 374 0.029
protein complex biogenesis GO:0070271 263 0.029
Rat
reproductive system development GO:0061458 128 0.028
Rat
response to ethanol GO:0045471 162 0.028
Rat
purine containing compound metabolic process GO:0072521 253 0.028
signal release GO:0023061 145 0.028
cellular response to drug GO:0035690 30 0.028
Rat
t cell extravasation GO:0072683 1 0.028
regulation of protein transport GO:0051223 68 0.028
female pregnancy GO:0007565 122 0.028
Rat
vasculature development GO:0001944 70 0.027
Rat
response to carbohydrate GO:0009743 183 0.027
head development GO:0060322 247 0.027
lipid localization GO:0010876 62 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
stress activated protein kinase signaling cascade GO:0031098 37 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
heterocycle catabolic process GO:0046700 167 0.027
interleukin 1 production GO:0032612 11 0.027
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.026
cognition GO:0050890 92 0.026
monosaccharide metabolic process GO:0005996 61 0.026
cell morphogenesis involved in differentiation GO:0000904 119 0.026
mast cell activation GO:0045576 15 0.026
regulation of lymphocyte migration GO:2000401 1 0.026
negative regulation of metabolic process GO:0009892 331 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
development of primary sexual characteristics GO:0045137 107 0.026
Rat

Mmp12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
gastrointestinal system cancer DOID:3119 0 0.034
cancer DOID:162 0 0.034
disease of cellular proliferation DOID:14566 0 0.034
organ system cancer DOID:0050686 0 0.034