IMP
Process View
microglial cell activation
The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
Loading network...
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "microglial cell activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Ptprc | protein tyrosine phosphatase, receptor type, C | 0.310 | ||
| Tlr4 | toll-like receptor 4 | 0.282 | ||
| Lyn | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.191 | ||
| Adam17 | ADAM metallopeptidase domain 17 | 0.172 | ||
| Casp1 | caspase 1 | 0.159 | ||
| Igsf6 | immunoglobulin superfamily, member 6 | 0.086 | ||
| Pdcl | phosducin-like | 0.079 | ||
| Cd38 | CD38 molecule | 0.069 | ||
| Arl11 | ADP-ribosylation factor-like 11 | 0.059 | ||
| Cd86 | CD86 molecule | 0.059 | ||
| Mmp12 | matrix metallopeptidase 12 | 0.058 | ||
| Cdk2 | cyclin dependent kinase 2 | 0.049 | ||
| Pla2g4a | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.049 | ||
| Nat1 | N-acetyltransferase 1 | 0.048 | ||
| Gucy2d | guanylate cyclase 2d | 0.046 | ||
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.044 | ||
| Calcrl | calcitonin receptor-like | 0.041 | ||
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.040 | ||
| Clec4a3 | C-type lectin domain family 4, member a3 | 0.039 | ||
| Casp8 | caspase 8 | 0.037 | Rat | |
| Casp12 | caspase 12 | 0.037 | Rat | |
| Drd3 | dopamine receptor D3 | 0.037 | ||
| RT1-N3 | RT1 class Ib, locus N3 | 0.034 | ||
| Klrc2 | killer cell lectin-like receptor subfamily C, member 2 | 0.032 | ||
| Tas2r126 | taste receptor, type 2, member 126 | 0.030 | ||
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.028 | ||
| Olr1496 | olfactory receptor 1496 | 0.028 | ||
| Casp2 | caspase 2 | 0.027 | Rat | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.027 | ||
| Ets1 | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 0.022 | ||
| Ocln | occludin | 0.022 | ||
| Cybb | cytochrome b-245, beta polypeptide | 0.021 | ||
| Tas2r118 | taste receptor, type 2, member 118 | 0.020 | ||
| Ifi204 | interferon activated gene 204 | 0.019 | ||
| Junb | jun B proto-oncogene | 0.018 | ||
| Dock8 | dedicator of cytokinesis 8 | 0.017 | ||
| Nmi | N-myc (and STAT) interactor | 0.017 | ||
| Tgfbr2 | transforming growth factor, beta receptor II | 0.017 | ||
| Casp3 | caspase 3 | 0.017 | Rat | |
| Klf6 | Kruppel-like factor 6 | 0.016 | ||
| Trpm8 | transient receptor potential cation channel, subfamily M, member 8 | 0.016 | ||
| Vom1r102 | vomeronasal 1 receptor 102 | 0.016 | ||
| Cd44 | Cd44 molecule | 0.016 | ||
| Cd48 | Cd48 molecule | 0.016 | ||
| Slco2b1 | solute carrier organic anion transporter family, member 2b1 | 0.016 | ||
| Top2a | topoisomerase (DNA) II alpha | 0.015 | ||
| Ctsc | cathepsin C | 0.015 | ||
| Elk3 | ELK3, ETS-domain protein | 0.015 | ||
| Adam2 | ADAM metallopeptidase domain 2 | 0.015 | ||
| Ccl22 | chemokine (C-C motif) ligand 22 | 0.014 | ||
| Plod2 | procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.014 | ||
| Myl7 | myosin, light chain 7, regulatory | 0.014 | ||
| Vegp1 | von Ebners gland protein 1 | 0.014 | ||
| Ppp1r15a | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.013 | ||
| Fcgr3a | Fc fragment of IgG, low affinity IIIa, receptor | 0.013 | ||
| Plau | plasminogen activator, urokinase | 0.013 | ||
| Serpinb3 | serine protease inhibitor B3 | 0.013 | ||
| P2ry6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 0.013 | ||
| Kcna2 | potassium voltage-gated channel, shaker-related subfamily, member 2 | 0.013 | ||
| Msn | moesin | 0.013 | ||
| Il2rg | interleukin 2 receptor, gamma | 0.012 | ||
| Glipr1 | GLI pathogenesis-related 1 | 0.012 | ||
| Parp14 | poly (ADP-ribose) polymerase family, member 14 | 0.012 | ||
| Rasgrp4 | RAS guanyl releasing protein 4 | 0.012 | ||
| Fam38b | family with sequence similarity 38, member B | 0.012 | ||
| Ptger2 | prostaglandin E receptor 2 (subtype EP2) | 0.012 | ||
| Clecsf6 | C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 6 | 0.012 | ||
| Smad1 | SMAD family member 1 | 0.012 | ||
| Hhipl1 | HHIP-like 1 | 0.012 | ||
| Prkcg | protein kinase C, gamma | 0.012 | ||
| Klhl6 | kelch-like 6 (Drosophila) | 0.012 | ||
| LOC685834 | similar to zinc finger protein 740 | 0.012 | ||
| Apaf1 | apoptotic peptidase activating factor 1 | 0.012 | ||
| Edn1 | endothelin 1 | 0.011 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.011 | ||
| Tlr7 | toll-like receptor 7 | 0.011 | ||
| RT1-A3 | RT1 class I, locus A3 | 0.011 | ||
| Cd8a | CD8a molecule | 0.011 | ||
| Skap2 | src kinase associated phosphoprotein 2 | 0.011 | ||
| Cyp11a1 | cytochrome P450, family 11, subfamily a, polypeptide 1 | 0.011 | ||
| Mlana | melan-A | 0.011 | ||
| LOC687856 | similar to Myeloid cell surface antigen CD33 precursor (Siglec-3) | 0.011 | ||
| Fas | Fas (TNF receptor superfamily, member 6) | 0.011 | ||
| Cdk11b | cyclin-dependent kinase 11B | 0.011 | ||
| Olr1082 | olfactory receptor 1082 | 0.011 | ||
| Akr1c14 | aldo-keto reductase family 1, member C14 | 0.011 | ||
| Cyp27b1 | cytochrome P450, family 27, subfamily b, polypeptide 1 | 0.011 | ||
| Map3k8 | mitogen-activated protein kinase kinase kinase 8 | 0.010 | ||
| Cd247 | Cd247 molecule | 0.010 | ||
| Htr1f | 5-hydroxytryptamine (serotonin) receptor 1F | 0.010 | ||
| Svs1 | seminal vesicle secretory protein 1 | 0.010 | ||
| Esr1 | estrogen receptor 1 | 0.010 |