Rattus norvegicus

0 known processes

Sfpq

splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)

(Aliases: MGC112723)

Sfpq biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.648
Mouse
nucleic acid templated transcription GO:0097659 379 0.611
Mouse
mrna processing GO:0006397 14 0.561
transcription from rna polymerase ii promoter GO:0006366 252 0.518
mrna stabilization GO:0048255 2 0.495
rna metabolic process GO:0016070 406 0.488
Mouse
rna biosynthetic process GO:0032774 380 0.465
Mouse
rna processing GO:0006396 22 0.404
alternative mrna splicing via spliceosome GO:0000380 4 0.368
ossification GO:0001503 70 0.308
regulation of mrna splicing via spliceosome GO:0048024 3 0.303
negative regulation of gene expression GO:0010629 199 0.264
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.251
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.213
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.203
Mouse
regulation of molecular function GO:0065009 398 0.200
regulation of cellular protein metabolic process GO:0032268 267 0.188
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.177
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.174
sexual reproduction GO:0019953 148 0.169
regulation of nucleic acid templated transcription GO:1903506 380 0.166
Mouse
signal transduction by phosphorylation GO:0023014 144 0.161
posttranscriptional regulation of gene expression GO:0010608 37 0.157
rna stabilization GO:0043489 2 0.152
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.150
Mouse
regulation of transcription dna templated GO:0006355 374 0.146
Mouse
nucleosome organization GO:0034728 1 0.141
protein localization to organelle GO:0033365 57 0.140
reproductive process GO:0022414 372 0.136
negative regulation of rna biosynthetic process GO:1902679 118 0.134
Mouse
response to reactive oxygen species GO:0000302 120 0.134
positive regulation of gene expression GO:0010628 244 0.133
cellular response to oxygen containing compound GO:1901701 386 0.130
organic acid metabolic process GO:0006082 292 0.127
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.125
negative regulation of biosynthetic process GO:0009890 168 0.124
Mouse
negative regulation of macromolecule metabolic process GO:0010605 260 0.115
Mouse
organelle organization GO:0006996 266 0.113
Mouse
positive regulation of rna biosynthetic process GO:1902680 197 0.111
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.109
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.107
regulation of cell differentiation GO:0045595 320 0.106
nucleocytoplasmic transport GO:0006913 48 0.106
positive regulation of signaling GO:0023056 270 0.105
regulation of neurogenesis GO:0050767 247 0.105
circadian regulation of gene expression GO:0032922 3 0.103
regulation of mrna stability GO:0043488 3 0.103
regulation of intracellular signal transduction GO:1902531 218 0.102
positive regulation of transcription dna templated GO:0045893 197 0.098
immune response GO:0006955 104 0.097
transcription dna templated GO:0006351 377 0.096
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.096
chromatin assembly or disassembly GO:0006333 1 0.094
negative regulation of metabolic process GO:0009892 331 0.094
Mouse
rna splicing via transesterification reactions GO:0000375 7 0.092
neuron projection development GO:0031175 273 0.091
regulation of protein metabolic process GO:0051246 289 0.087
coenzyme metabolic process GO:0006732 86 0.085
regulation of rna biosynthetic process GO:2001141 381 0.084
Mouse
negative regulation of rna splicing GO:0033119 3 0.083
response to radiation GO:0009314 137 0.082
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.082
mrna 3 end processing GO:0031124 1 0.081
anatomical structure morphogenesis GO:0009653 298 0.081
positive regulation of cell communication GO:0010647 271 0.080
positive regulation of developmental process GO:0051094 283 0.079
multi organism reproductive process GO:0044703 262 0.079
reproduction GO:0000003 245 0.078
single organism reproductive process GO:0044702 297 0.078
regulation of multicellular organismal development GO:2000026 376 0.078
cofactor metabolic process GO:0051186 95 0.076
rna splicing GO:0008380 11 0.075
multicellular organismal reproductive process GO:0048609 233 0.073
positive regulation of nucleic acid templated transcription GO:1903508 197 0.073
negative regulation of rna metabolic process GO:0051253 123 0.072
Mouse
negative regulation of developmental process GO:0051093 125 0.071
spindle organization GO:0007051 2 0.068
cellular component movement GO:0006928 248 0.067
regulation of organelle organization GO:0033043 80 0.067
regulation of phosphate metabolic process GO:0019220 349 0.064
osteoblast differentiation GO:0001649 26 0.064
regulation of rna stability GO:0043487 3 0.064
cellular response to stress GO:0033554 269 0.062
regulation of neuron differentiation GO:0045664 208 0.062
multi multicellular organism process GO:0044706 138 0.060
regulation of mapk cascade GO:0043408 116 0.060
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.060
sulfur compound metabolic process GO:0006790 70 0.060
hemidesmosome assembly GO:0031581 1 0.057
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.056
meiotic chromosome segregation GO:0045132 1 0.055
cellular component assembly GO:0022607 360 0.054
organic acid biosynthetic process GO:0016053 83 0.053
oxoacid metabolic process GO:0043436 290 0.052
cellular amino acid metabolic process GO:0006520 107 0.051
regulation of cellular component organization GO:0051128 368 0.051
negative regulation of cell proliferation GO:0008285 119 0.050
cellular component biogenesis GO:0044085 368 0.050
mrna metabolic process GO:0016071 20 0.050
gamete generation GO:0007276 124 0.049
circulatory system development GO:0072359 134 0.049
positive regulation of cellular biosynthetic process GO:0031328 295 0.048
regulation of signal transduction GO:0009966 318 0.048
angiogenesis GO:0001525 53 0.048
learning GO:0007612 33 0.047
brain development GO:0007420 247 0.047
multicellular organism reproduction GO:0032504 233 0.046
cellular homeostasis GO:0019725 252 0.046
germ cell migration GO:0008354 1 0.046
negative regulation of multicellular organismal process GO:0051241 203 0.045
cellular component morphogenesis GO:0032989 155 0.045
positive regulation of rna metabolic process GO:0051254 203 0.045
mitotic spindle organization GO:0007052 2 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.044
negative regulation of transcription dna templated GO:0045892 116 0.044
Mouse
chemosensory behavior GO:0007635 2 0.044
cellular metal ion homeostasis GO:0006875 172 0.044
carboxylic acid metabolic process GO:0019752 289 0.043
nitrogen compound transport GO:0071705 229 0.043
sulfur compound biosynthetic process GO:0044272 19 0.040
positive regulation of cell differentiation GO:0045597 217 0.040
positive regulation of response to stimulus GO:0048584 285 0.040
establishment of chromosome localization GO:0051303 1 0.039
spermine metabolic process GO:0008215 4 0.039
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.039
chromosome segregation GO:0007059 2 0.039
intracellular signal transduction GO:0035556 314 0.038
positive regulation of cellular component biogenesis GO:0044089 55 0.038
adult locomotory behavior GO:0008344 4 0.038
multicellular organism growth GO:0035264 1 0.037
regulation of anatomical structure size GO:0090066 135 0.037
response to extracellular stimulus GO:0009991 380 0.037
cellular chemical homeostasis GO:0055082 247 0.036
positive regulation of neurogenesis GO:0050769 165 0.036
rhythmic process GO:0048511 156 0.035
Mouse
glucan metabolic process GO:0044042 23 0.035
macromolecular complex assembly GO:0065003 273 0.035
central nervous system development GO:0007417 311 0.034
response to nutrient levels GO:0031667 370 0.034
oxidation reduction process GO:0055114 304 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
growth GO:0040007 165 0.033
positive regulation of neuron differentiation GO:0045666 126 0.033
cell projection organization GO:0030030 302 0.033
associative learning GO:0008306 19 0.033
regulation of angiogenesis GO:0045765 39 0.033
single organism behavior GO:0044708 130 0.033
regulation of catalytic activity GO:0050790 304 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
dna packaging GO:0006323 4 0.032
cell morphogenesis involved in differentiation GO:0000904 119 0.032
cellular catabolic process GO:0044248 295 0.031
embryo development GO:0009790 49 0.031
regulation of stem cell proliferation GO:0072091 14 0.031
cell cycle GO:0007049 101 0.030
axis specification GO:0009798 4 0.030
positive regulation of apoptotic process GO:0043065 154 0.029
regulation of protein import into nucleus GO:0042306 24 0.029
blood vessel development GO:0001568 69 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
protein targeting to nucleus GO:0044744 35 0.029
protein maturation GO:0051604 68 0.029
regulation of phosphorylation GO:0042325 248 0.028
ion homeostasis GO:0050801 212 0.028
single organism carbohydrate metabolic process GO:0044723 118 0.028
neuron development GO:0048666 286 0.028
meiotic cell cycle process GO:1903046 3 0.028
reactive oxygen species metabolic process GO:0072593 37 0.027
regulation of growth GO:0040008 105 0.027
proteolysis GO:0006508 175 0.027
regulation of cell development GO:0060284 263 0.027
positive regulation of programmed cell death GO:0043068 157 0.027
response to wounding GO:0009611 254 0.027
positive regulation of nervous system development GO:0051962 178 0.026
regulation of protein modification process GO:0031399 194 0.026
negative regulation of protein metabolic process GO:0051248 114 0.026
regulation of programmed cell death GO:0043067 341 0.026
negative regulation of mrna splicing via spliceosome GO:0048025 2 0.026
carboxylic acid biosynthetic process GO:0046394 83 0.025
chromatin remodeling GO:0006338 3 0.025
organonitrogen compound biosynthetic process GO:1901566 167 0.025
apoptotic process GO:0006915 381 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
regulation of nervous system development GO:0051960 264 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
ribonucleoprotein complex biogenesis GO:0022613 10 0.024
macromolecule localization GO:0033036 252 0.024
developmental growth GO:0048589 100 0.024
mapk cascade GO:0000165 140 0.024
homeostatic process GO:0042592 331 0.024
cellular cation homeostasis GO:0030003 180 0.023
cellular response to lipid GO:0071396 201 0.023
chromatin modification GO:0016568 33 0.023
Mouse
dendrite development GO:0016358 72 0.023
carbohydrate metabolic process GO:0005975 130 0.023
response to decreased oxygen levels GO:0036293 237 0.022
cell cycle process GO:0022402 57 0.022
visual learning GO:0008542 8 0.022
protein import into nucleus GO:0006606 35 0.022
chemical homeostasis GO:0048878 292 0.022
cell growth GO:0016049 104 0.022
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.022
cellular response to cytokine stimulus GO:0071345 127 0.022
modification dependent macromolecule catabolic process GO:0043632 14 0.022
positive regulation of molecular function GO:0044093 230 0.022
reactive oxygen species biosynthetic process GO:1903409 8 0.022
regulation of protein targeting GO:1903533 28 0.022
embryonic pattern specification GO:0009880 1 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
positive regulation of adherens junction organization GO:1903393 2 0.021
single organism biosynthetic process GO:0044711 342 0.021
cell type specific apoptotic process GO:0097285 134 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
negative regulation of cell differentiation GO:0045596 99 0.021
positive regulation of cell death GO:0010942 184 0.021
positive regulation of signal transduction GO:0009967 175 0.021
positive regulation of protein modification process GO:0031401 142 0.021
single organism organelle organization GO:1902589 180 0.021
Mouse
positive regulation of angiogenesis GO:0045766 28 0.021
photoperiodism GO:0009648 4 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
protein complex subunit organization GO:0071822 302 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
signal transduction involved in regulation of gene expression GO:0023019 4 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
cellular amine metabolic process GO:0044106 38 0.020
regulation of cellular localization GO:0060341 263 0.020
dna metabolic process GO:0006259 96 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
embryonic axis specification GO:0000578 1 0.019
metal ion homeostasis GO:0055065 186 0.019
tissue development GO:0009888 252 0.019
response to transforming growth factor beta GO:0071559 46 0.019
transmembrane transport GO:0055085 412 0.019
behavior GO:0007610 205 0.019
gastrulation GO:0007369 2 0.019
single organism nuclear import GO:1902593 35 0.019
nuclear transport GO:0051169 49 0.019
response to bacterium GO:0009617 200 0.019
cellular modified amino acid metabolic process GO:0006575 61 0.019
regulation of epithelial cell proliferation GO:0050678 49 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
cellular macromolecular complex assembly GO:0034622 58 0.019
cellular ion homeostasis GO:0006873 184 0.018
cellular modified amino acid biosynthetic process GO:0042398 18 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
Mouse
organic substance catabolic process GO:1901575 316 0.018
positive regulation of neuron projection development GO:0010976 99 0.018
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
blood vessel morphogenesis GO:0048514 58 0.018
cytoplasmic transport GO:0016482 115 0.018
response to organophosphorus GO:0046683 102 0.018
regulation of cell proliferation GO:0042127 359 0.018
cellular macromolecule localization GO:0070727 122 0.017
mesoderm morphogenesis GO:0048332 1 0.017
protein complex biogenesis GO:0070271 263 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 7 0.017
aging GO:0007568 241 0.017
catabolic process GO:0009056 351 0.017
regeneration GO:0031099 163 0.017
negative regulation of cell death GO:0060548 229 0.017
entrainment of circadian clock GO:0009649 3 0.017
mesoderm development GO:0007498 2 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
negative regulation of mrna metabolic process GO:1903312 3 0.017
response to purine containing compound GO:0014074 126 0.016
cardiovascular system development GO:0072358 134 0.016
response to growth factor GO:0070848 189 0.016
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.016
response to ethanol GO:0045471 162 0.016
neuron projection morphogenesis GO:0048812 122 0.016
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.016
rna localization GO:0006403 4 0.016
olfactory behavior GO:0042048 2 0.015
cell cycle checkpoint GO:0000075 2 0.015
muscle cell apoptotic process GO:0010657 30 0.015
olfactory learning GO:0008355 1 0.015
cellular protein localization GO:0034613 122 0.015
sister chromatid segregation GO:0000819 1 0.015
programmed cell death GO:0012501 392 0.015
defense response GO:0006952 194 0.015
respiratory system development GO:0060541 45 0.015
amine metabolic process GO:0009308 38 0.015
locomotion GO:0040011 237 0.015
developmental process involved in reproduction GO:0003006 159 0.015
cell morphogenesis GO:0000902 142 0.015
spermatogenesis GO:0007283 99 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
male mating behavior GO:0060179 3 0.014
tube development GO:0035295 89 0.014
myosin filament assembly GO:0031034 1 0.014
response to inorganic substance GO:0010035 377 0.014
cellular response to alcohol GO:0097306 87 0.014
protein complex assembly GO:0006461 263 0.014
protein refolding GO:0042026 3 0.014
response to vitamin GO:0033273 131 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
calcium ion homeostasis GO:0055074 162 0.014
metaphase plate congression GO:0051310 1 0.014
negative regulation of neuron death GO:1901215 69 0.014
signal release GO:0023061 145 0.014
cell activation GO:0001775 97 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.013
regulation of proteolysis GO:0030162 66 0.013
response to camp GO:0051591 91 0.013
intracellular transport GO:0046907 185 0.013
muscle structure development GO:0061061 87 0.013
response to light stimulus GO:0009416 52 0.013
regulation of reactive oxygen species metabolic process GO:2000377 26 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
cellular polysaccharide metabolic process GO:0044264 23 0.013
response to other organism GO:0051707 220 0.013
activation of cysteine type endopeptidase activity GO:0097202 4 0.013
b cell mediated immunity GO:0019724 4 0.013
positive regulation of cell development GO:0010720 176 0.013
negative regulation of molecular function GO:0044092 133 0.013
stem cell differentiation GO:0048863 16 0.013
response to peptide hormone GO:0043434 278 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
response to metal ion GO:0010038 253 0.013
neurological system process GO:0050877 219 0.013
stem cell development GO:0048864 11 0.012
nuclear import GO:0051170 35 0.012
cellular macromolecule catabolic process GO:0044265 29 0.012
innate immune response GO:0045087 35 0.012
male gamete generation GO:0048232 99 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of dendrite development GO:0050773 59 0.012
anterior posterior pattern specification GO:0009952 1 0.012
bmp signaling pathway GO:0030509 4 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
positive regulation of growth GO:0045927 55 0.012
transforming growth factor beta3 production GO:0032907 2 0.012
myeloid leukocyte mediated immunity GO:0002444 12 0.012
mitotic cell cycle checkpoint GO:0007093 1 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
female pregnancy GO:0007565 122 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
leukocyte activation involved in immune response GO:0002366 16 0.012
kidney development GO:0001822 67 0.012
regulation of intracellular transport GO:0032386 65 0.012
purine ribonucleoside biosynthetic process GO:0046129 21 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
Mouse
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
centrosome cycle GO:0007098 1 0.012
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 3 0.012
negative regulation of signaling GO:0023057 157 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
response to endoplasmic reticulum stress GO:0034976 10 0.012
regulation of apoptotic process GO:0042981 335 0.011
glycogen metabolic process GO:0005977 23 0.011
regulation of mrna processing GO:0050684 5 0.011
cellular response to oxygen levels GO:0071453 60 0.011
single organism intracellular transport GO:1902582 166 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
negative regulation of peptidase activity GO:0010466 38 0.011
protein import GO:0017038 37 0.011
peptide secretion GO:0002790 86 0.011
negative regulation of nervous system development GO:0051961 79 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
female gamete generation GO:0007292 25 0.011
hormone transport GO:0009914 121 0.011
regulation of alkaline phosphatase activity GO:0010692 2 0.011
lipid biosynthetic process GO:0008610 128 0.011
regulation of mitotic sister chromatid segregation GO:0033047 1 0.011
regulation of cell projection organization GO:0031344 175 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 1 0.011
formation of primary germ layer GO:0001704 1 0.011
circadian rhythm GO:0007623 88 0.011
Mouse
hormone secretion GO:0046879 115 0.011
muscle cell differentiation GO:0042692 52 0.011
amide transport GO:0042886 105 0.011
head development GO:0060322 247 0.011
regulation of cell cycle GO:0051726 73 0.011
response to hypoxia GO:0001666 231 0.011
cell cell signaling GO:0007267 335 0.011
regulation of protein maturation GO:1903317 50 0.011
urogenital system development GO:0001655 78 0.011
inflammatory response GO:0006954 150 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
proteasomal protein catabolic process GO:0010498 8 0.011
protein oligomerization GO:0051259 191 0.011
microtubule based process GO:0007017 36 0.011
multicellular organismal catabolic process GO:0044243 2 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 35 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
positive regulation of chemotaxis GO:0050921 23 0.011
intracellular protein transport GO:0006886 79 0.010
response to peptide GO:1901652 292 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.010
regulation of hormone secretion GO:0046883 106 0.010
immune effector process GO:0002252 53 0.010
regulation of vasculature development GO:1901342 44 0.010
positive regulation of bone mineralization GO:0030501 4 0.010
regulation of sister chromatid segregation GO:0033045 1 0.010
mast cell activation involved in immune response GO:0002279 10 0.010
regulation of peptide secretion GO:0002791 82 0.010
gliogenesis GO:0042063 93 0.010
lymphocyte homeostasis GO:0002260 2 0.010
microtubule cytoskeleton organization GO:0000226 25 0.010
protein targeting GO:0006605 61 0.010
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.010
mesoderm formation GO:0001707 1 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
glycoprotein biosynthetic process GO:0009101 19 0.010
peptide transport GO:0015833 97 0.010

Sfpq disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
central nervous system disease DOID:331 0 0.016