IMP

Process View

Rattus norvegicus

24 genes annotated in rat

Multi-species View

regulation of protein import into nucleus

GO:0042306

Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of protein import into nucleus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of protein import into nucleus" (in gray)

Name	Description	Probability	Func Analog Organism
Ywhag	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.309
Hsph1	heat shock 105/110 protein 1	0.274
Mprip	myosin phosphatase Rho interacting protein	0.239
Fkbp4	FK506 binding protein 4	0.183
Stip1	stress-induced phosphoprotein 1	0.165
Rara	retinoic acid receptor, alpha	0.163
Hspa8	heat shock protein 8	0.150
Tgfbr2	transforming growth factor, beta receptor II	0.128
Hist1h1a	histone cluster 1, H1a	0.117
Ppp2cb	protein phosphatase 2, catalytic subunit, beta isoform	0.097	Rat
Igfbp5	insulin-like growth factor binding protein 5	0.093
Ptp4a1	protein tyrosine phosphatase type IVA, member 1	0.092
Icam1	intercellular adhesion molecule 1	0.087
Tnks2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.080
Mapk1	mitogen activated protein kinase 1	0.072
Fgfr1	Fibroblast growth factor receptor 1	0.071
Map2k1	mitogen activated protein kinase kinase 1	0.070
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.069
Irf1	interferon regulatory factor 1	0.063
Sf1	splicing factor 1	0.062
Errfi1	ERBB receptor feedback inhibitor 1	0.061
Pdcd4	programmed cell death 4	0.061
Smad7	SMAD family member 7	0.060
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.060
Ide	insulin degrading enzyme	0.057
Eef2	eukaryotic translation elongation factor 2	0.055
Taf6	TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor	0.054
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.054
Slit3	slit homolog 3 (Drosophila)	0.053
Stat6	signal transducer and activator of transcription 6	0.052
Dnaja2	DnaJ (Hsp40) homolog, subfamily A, member 2	0.049
Dynll1	dynein light chain LC8-type 1	0.047
Cacna1c	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.046
Hsp90aa1	heat shock protein 90, alpha (cytosolic), class A member 1	0.044
Tgfb2	transforming growth factor, beta 2	0.043
Sec61g	SEC61, gamma subunit	0.042
Ppp2r2a	protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform	0.042
Hivep2	human immunodeficiency virus type I enhancer binding protein 2	0.042
Nckap1	NCK-associated protein 1	0.041
Lbr	lamin B receptor	0.040
Ptges3	prostaglandin E synthase 3 (cytosolic)	0.040
Ppp3cb	protein phosphatase 3, catalytic subunit, beta isoform	0.040	Fly
Ltbr	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.040
Smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.039
Hmox1	heme oxygenase (decycling) 1	0.039
Myo1c	myosin IC	0.038
Lims1	LIM and senescent cell antigen-like domains 1	0.037
Crk	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.036
Ehmt2	euchromatic histone lysine N-methyltransferase 2	0.036
Csnk2a2	casein kinase 2, alpha prime polypeptide	0.035
Akt1s1	AKT1 substrate 1 (proline-rich)	0.035
Cxcl10	chemokine (C-X-C motif) ligand 10	0.034
Casp2	caspase 2	0.034
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.034
Cdk2	cyclin dependent kinase 2	0.034	Rat
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.033
Pdgfb	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.033
Met	met proto-oncogene	0.033
Gna12	guanine nucleotide binding protein (G protein) alpha 12	0.032
Pcyox1	prenylcysteine oxidase 1	0.032
Lpl	lipoprotein lipase	0.032
Snrk	SNF related kinase	0.032
St13	suppression of tumorigenicity 13	0.032
Ccnd3	cyclin D3	0.031
Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	0.031
Tcf3	transcription factor 3	0.031
Tcf4	transcription factor 4	0.030
Tp53	tumor protein p53	0.030
Serpinh1	serine (or cysteine) peptidase inhibitor, clade H, member 1	0.030
Sfpq	splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)	0.029
Dag1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.029
Atp2b1	ATPase, Ca++ transporting, plasma membrane 1	0.029
Smg5	Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.028
Mapk6	mitogen-activated protein kinase 6	0.027
Jak1	Janus kinase 1	0.027
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.027
Cpd	carboxypeptidase D	0.027
Dnaja1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.026
Calcrl	calcitonin receptor-like	0.026
Synj1	synaptojanin 1	0.025
Hspd1	heat shock protein 1 (chaperonin)	0.025
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.025
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.025
Zfp36	zinc finger protein 36	0.024
Exoc5	exocyst complex component 5	0.024
Gja5	gap junction protein, alpha 5	0.024
Bat3	HLA-B-associated transcript 3	0.024
Bgn	biglycan	0.024
Hspa9	heat shock protein 9	0.024
Olr1	oxidized low density lipoprotein (lectin-like) receptor 1	0.024
Ctdsp1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	0.023
Dchs1	dachsous 1 (Drosophila)	0.023
Mstn	myostatin	0.023
Oaz2	ornithine decarboxylase antizyme 2	0.023
Rxra	retinoid X receptor alpha	0.022	Rat
Dnajb1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.022
Ate1	arginyltransferase 1	0.022
Stat5b	signal transducer and activator of transcription 5B	0.022
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.022
Cul3	cullin 3	0.022
Znf503	zinc finger protein 503	0.021
Cyfip2	cytoplasmic FMR1 interacting protein 2	0.021
Nfib	nuclear factor I/B	0.021
Nrd1	nardilysin 1	0.021
Ppm1g	protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform	0.021
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.021
Mib1	mindbomb homolog 1 (Drosophila)	0.020
Fmnl1	formin-like 1	0.020
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.020
Eif1	eukaryotic translation initiation factor 1	0.020
Ispd	isoprenoid synthase domain containing	0.020
Ifrd1	interferon-related developmental regulator 1	0.020
Sdc3	syndecan 3	0.019
Tnf	tumor necrosis factor (TNF superfamily, member 2)	0.019	Mouse
Kpna1	karyopherin alpha 1	0.019
Bok	BCL2-related ovarian killer	0.019
Sf3b4	splicing factor 3b, subunit 4	0.019
RGD1559588	similar to cell surface receptor FDFACT	0.019
Ptgs2	prostaglandin-endoperoxide synthase 2	0.018
Rest	RE1-silencing transcription factor	0.018
Supt16h	suppressor of Ty 16 homolog (S. cerevisiae)	0.018
Ece1	endothelin converting enzyme 1	0.018
Rab5b	RAB5B, member RAS oncogene family	0.018
Plxnb2	plexin B2	0.018
Socs3	suppressor of cytokine signaling 3	0.018
Rabep2	rabaptin, RAB GTPase binding effector protein 2	0.018
Ccne1	cyclin E1	0.018
Kcmf1	potassium channel modulatory factor 1	0.018
Axin1	axin 1	0.018	Mouse
Eif4h	eukaryotic translation initiation factor 4H	0.017
Cops7a	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	0.017
Syngr2	synaptogyrin 2	0.017
Tnfaip2	tumor necrosis factor, alpha-induced protein 2	0.017
Mtx2	metaxin 2	0.017
Map2k5	mitogen activated protein kinase kinase 5	0.017
Gna11	guanine nucleotide binding protein, alpha 11	0.017
Foxi2	forkhead box I2	0.017
Tcfe2a	transcription factor E2a	0.017
Map3k7ip1	mitogen-activated protein kinase kinase kinase 7 interacting protein 1	0.016
Rab20	RAB20, member RAS oncogene family	0.016
Notch1	Notch homolog 1, translocation-associated (Drosophila)	0.016
Sgk1	serum/glucocorticoid regulated kinase 1	0.016
Adrb2	adrenergic, beta-2-, receptor, surface	0.016
Myo1b	myosin Ib	0.016
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.016	Rat
Acsl4	acyl-CoA synthetase long-chain family member 4	0.016
Mgat1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.016
Efnb1	ephrin B1	0.016
Ahr	aryl hydrocarbon receptor	0.016
Nr4a3	nuclear receptor subfamily 4, group A, member 3	0.016
Nr2f6	nuclear receptor subfamily 2, group F, member 6	0.016	Rat
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.016
Ran	RAN, member RAS oncogene family	0.016
Kif2a	kinesin family member 2A	0.016
Fgfr4	fibroblast growth factor receptor 4	0.015
Myd88	myeloid differentiation primary response gene 88	0.015
Socs5	suppressor of cytokine signaling 5	0.015
Dcaf8	DDB1 and CUL4 associated factor 8	0.015
Gucy1b3	guanylate cyclase 1, soluble, beta 3	0.015
Grik2	glutamate receptor, ionotropic, kainate 2	0.015
Csnk1g2	casein kinase 1, gamma 2	0.015
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.015
Pde4a	phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)	0.015
Map3k3	mitogen activated protein kinase kinase kinase 3	0.015
Rho	rhodopsin	0.015
Gria2	glutamate receptor, ionotropic, AMPA 2	0.014
Larp1	La ribonucleoprotein domain family, member 1	0.014
Mmp14	matrix metallopeptidase 14 (membrane-inserted)	0.014
Slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.014
Sh2b1	SH2B adaptor protein 1	0.014
Ereg	epiregulin	0.014
Ppp2ca	protein phosphatase 2, catalytic subunit, alpha isoform	0.014
Mapk3	mitogen activated protein kinase 3	0.014
Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	0.014
Gstm2	glutathione S-transferase mu 2	0.014
Ppp2r5e	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.014
Mdm2	Mdm2 p53 binding protein homolog (mouse)	0.014
Hivep1	human immunodeficiency virus type I enhancer binding protein 1	0.014
Gsr	glutathione reductase	0.014
Akt1	v-akt murine thymoma viral oncogene homolog 1	0.014	Rat
Meox2	mesenchyme homeobox 2	0.014
Ctbp1	C-terminal binding protein 1	0.014
Ednrb	endothelin receptor type B	0.014
Cast	calpastatin	0.014
Dusp2	dual specificity phosphatase 2	0.013
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.013
Papd5	PAP associated domain containing 5	0.013
Orai1	ORAI calcium release-activated calcium modulator 1	0.013
Adam10	ADAM metallopeptidase domain 10	0.013
Hnrpd	heterogeneous nuclear ribonucleoprotein D	0.013
Jak2	Janus kinase 2	0.013
Gata4	GATA binding protein 4	0.013
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.013
Trim3	tripartite motif-containing 3	0.013
Tmem101	transmembrane protein 101	0.013
Cnksr2	connector enhancer of kinase suppressor of Ras 2	0.013
Cyth1	cytohesin 1	0.013
Stat3	signal transducer and activator of transcription 3	0.013
Map2	microtubule-associated protein 2	0.013
Dnajc14	DnaJ (Hsp40) homolog, subfamily C, member 14	0.013
Pip4k2b	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.013
Klf9	Kruppel-like factor 9	0.013
Tle2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)	0.013
Ccl4	chemokine (C-C motif) ligand 4	0.013
Rnd1	Rho family GTPase 1	0.013
Ptbp1	polypyrimidine tract binding protein 1	0.013
Vipr1	vasoactive intestinal peptide receptor 1	0.013
Smad3	SMAD family member 3	0.013	Human
Pafah1b1	platelet-activating factor acetylhydrolase, isoform 1b, subunit 1	0.013
Cx3cl1	chemokine (C-X3-C motif) ligand 1	0.013
Vapa	VAMP (vesicle-associated membrane protein)-associated protein A	0.013	Yeast
Pard3	par-3 (partitioning defective 3) homolog (C. elegans)	0.012
Thop1	thimet oligopeptidase 1	0.012
Mmp23	matrix metallopeptidase 23	0.012
Ptprd	protein tyrosine phosphatase, receptor type, D	0.012
Ripk3	receptor-interacting serine-threonine kinase 3	0.012
Tnnt2	troponin T type 2 (cardiac)	0.012
Trim17	tripartite motif-containing 17	0.012
Ptprk	protein tyrosine phosphatase, receptor type, K, extracellular region	0.012
Junb	jun B proto-oncogene	0.012
Tpc1808	tropic 1808	0.012
Gphn	gephyrin	0.012
Park2	Parkinson disease (autosomal recessive, juvenile) 2, parkin	0.012
Tgfbr3	transforming growth factor, beta receptor III	0.012
Camkk2	calcium/calmodulin-dependent protein kinase kinase 2, beta	0.012
Hes1	hairy and enhancer of split 1 (Drosophila)	0.012
Myc	myelocytomatosis oncogene	0.012
Il6	interleukin 6	0.012
Serpine1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.012
Trip12	thyroid hormone receptor interactor 12	0.012
Agtr1a	angiotensin II receptor, type 1a	0.012
Grin1	glutamate receptor, ionotropic, N-methyl D-aspartate 1	0.012
Ccl2	chemokine (C-C motif) ligand 2	0.012
Vcan	versican	0.012
Foxo1	forkhead box O1	0.012
Cttnbp2	cortactin binding protein 2	0.012
Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	0.012
Tlr2	toll-like receptor 2	0.012
Gria3	glutamate receptor, ionotrophic, AMPA 3	0.012
Usp14	ubiquitin specific peptidase 14	0.012
Tfpi2	tissue factor pathway inhibitor 2	0.012
Negr1	neuronal growth regulator 1	0.012
LOC687856	similar to Myeloid cell surface antigen CD33 precursor (Siglec-3)	0.011
Top2a	topoisomerase (DNA) II alpha	0.011
Zfand3	zinc finger, AN1-type domain 3	0.011
Il1a	interleukin 1 alpha	0.011
Dlg4	discs, large homolog 4 (Drosophila)	0.011
Lphn1	latrophilin 1	0.011
Ccl3	chemokine (C-C motif) ligand 3	0.011
Pdc	phosducin	0.011
Stx2	syntaxin 2	0.011
Ccdc91	coiled-coil domain containing 91	0.011
Sult1c2	sulfotransferase family, cytosolic, 1C, member 2	0.011
Nln	neurolysin (metallopeptidase M3 family)	0.011
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.011
F13a1	coagulation factor XIII, A1 polypeptide	0.011
Nudt3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.011
Thra	thyroid hormone receptor alpha	0.011	Mouse
Msl1	male-specific lethal 1 homolog (Drosophila)	0.011
Rraga	Ras-related GTP binding A	0.011
Eef2k	eukaryotic elongation factor-2 kinase	0.011
Ccl7	chemokine (C-C motif) ligand 7	0.011
Slc26a5	solute carrier family 26, member 5 (prestin)	0.011
Arhgap25	Rho GTPase activating protein 25	0.011
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.011	Mouse
Lpar4	lysophosphatidic acid receptor 4	0.011
Pcyt1a	phosphate cytidylyltransferase 1, choline, alpha	0.011
Gas7	growth arrest specific 7	0.011
Pqcp	polyglutamine-containing protein	0.011
Acvr2a	activin A receptor, type IIA	0.011
Clic4	chloride intracellular channel 4	0.010
Fbxo32	F-box protein 32	0.010
Il7r	interleukin 7 receptor	0.010
Mical1	microtubule associated monoxygenase, calponin and LIM domain containing 1	0.010
Kif16b	kinesin family member 16B	0.010
Foxg1	forkhead box G1	0.010
Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)	0.010
Art3	ADP-ribosyltransferase 3	0.010
Dnase1l3	deoxyribonuclease 1-like 3	0.010
Casp7	caspase 7	0.010
Clcn4-2	chloride channel 4-2	0.010
Slc9a2	solute carrier family 9 (sodium/hydrogen exchanger), member 2	0.010
Myo1g	myosin IG	0.010
Epn1	Epsin 1	0.010
Gja1	gap junction protein, alpha 1	0.010
Eif4g1	eukaryotic translation initiation factor 4 gamma, 1	0.010
Rhobtb2	Rho-related BTB domain containing 2	0.010
Cnn1	calponin 1, basic, smooth muscle	0.010
Adm	adrenomedullin	0.010
Nars	asparaginyl-tRNA synthetase	0.010
Cd83	CD83 molecule	0.010