Rattus norvegicus

52 known processes

Slc9a3

solute carrier family 9 (sodium/hydrogen exchanger), member 3

(Aliases: Nhe3)

Slc9a3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
monocarboxylic acid metabolic process GO:0032787 152 0.419
oxoacid metabolic process GO:0043436 290 0.268
inorganic cation transmembrane transport GO:0098662 202 0.248
cellular ion homeostasis GO:0006873 184 0.220
Rat
cation transport GO:0006812 382 0.212
regulation of blood pressure GO:0008217 83 0.211
cation transmembrane transport GO:0098655 263 0.211
muscle system process GO:0003012 115 0.170
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.149
regulation of hormone levels GO:0010817 187 0.149
response to nutrient levels GO:0031667 370 0.143
regulation of cellular component organization GO:0051128 368 0.131
Rat
fatty acid metabolic process GO:0006631 99 0.106
organic acid metabolic process GO:0006082 292 0.101
heart contraction GO:0060047 57 0.101
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.101
signal release GO:0023061 145 0.093
nitrogen compound transport GO:0071705 229 0.092
response to corticosteroid GO:0031960 235 0.087
homeostatic process GO:0042592 331 0.085
cation homeostasis GO:0055080 195 0.081
response to inorganic substance GO:0010035 377 0.081
monovalent inorganic cation transport GO:0015672 172 0.080
regulation of system process GO:0044057 208 0.079
Rat
ion transmembrane transport GO:0034220 365 0.077
positive regulation of cell communication GO:0010647 271 0.075
Rat
response to vitamin GO:0033273 131 0.071
cellular component assembly GO:0022607 360 0.070
positive regulation of secretion by cell GO:1903532 128 0.070
response to nutrient GO:0007584 248 0.070
blood circulation GO:0008015 183 0.067
Rat
metal ion homeostasis GO:0055065 186 0.058
hormone transport GO:0009914 121 0.056
response to toxic substance GO:0009636 133 0.055
Rat
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.055
chemical homeostasis GO:0048878 292 0.054
intracellular signal transduction GO:0035556 314 0.053
Rat
catecholamine secretion GO:0050432 33 0.051
striated muscle contraction GO:0006941 44 0.051
Rat
response to glucocorticoid GO:0051384 223 0.050
protein complex subunit organization GO:0071822 302 0.050
circulatory system process GO:0003013 183 0.049
Rat
metal ion transport GO:0030001 289 0.049
heart process GO:0003015 57 0.049
Rat
cellular response to oxygen containing compound GO:1901701 386 0.048
Rat
carboxylic acid metabolic process GO:0019752 289 0.048
cellular calcium ion homeostasis GO:0006874 160 0.046
response to metal ion GO:0010038 253 0.046
cellular chemical homeostasis GO:0055082 247 0.045
Rat
response to extracellular stimulus GO:0009991 380 0.044
regulation of rna metabolic process GO:0051252 391 0.044
cellular lipid metabolic process GO:0044255 208 0.044
rna metabolic process GO:0016070 406 0.043
defense response GO:0006952 194 0.041
regulation of secretion GO:0051046 224 0.041
transmembrane transport GO:0055085 412 0.041
calcitriol biosynthetic process from calciol GO:0036378 2 0.040
response to starvation GO:0042594 59 0.040
inorganic ion transmembrane transport GO:0098660 229 0.040
positive regulation of signaling GO:0023056 270 0.040
Rat
nucleic acid templated transcription GO:0097659 379 0.040
cellular metal ion homeostasis GO:0006875 172 0.039
rna biosynthetic process GO:0032774 380 0.039
defecation GO:0030421 1 0.039
response to ketone GO:1901654 182 0.039
cellular divalent inorganic cation homeostasis GO:0072503 162 0.038
cellular component biogenesis GO:0044085 368 0.036
cellular response to nitrogen compound GO:1901699 210 0.036
Rat
catabolic process GO:0009056 351 0.035
single organism biosynthetic process GO:0044711 342 0.035
regulation of transcription dna templated GO:0006355 374 0.034
positive regulation of transport GO:0051050 245 0.034
cellular cation homeostasis GO:0030003 180 0.034
Rat
response to peptide hormone GO:0043434 278 0.034
Rat
regulation of cellular localization GO:0060341 263 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
positive regulation of blood circulation GO:1903524 65 0.033
peptide secretion GO:0002790 86 0.033
organic substance catabolic process GO:1901575 316 0.033
sensory perception GO:0007600 101 0.033
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.032
regulation of ion transport GO:0043269 245 0.032
anion transport GO:0006820 178 0.032
secretion by cell GO:0032940 248 0.031
proteolysis GO:0006508 175 0.031
transcription dna templated GO:0006351 377 0.031
response to alkaloid GO:0043279 132 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.031
progesterone biosynthetic process GO:0006701 3 0.031
maintenance of location GO:0051235 17 0.030
regulation of blood circulation GO:1903522 110 0.030
Rat
protein complex assembly GO:0006461 263 0.030
cell cell signaling GO:0007267 335 0.030
calcium ion homeostasis GO:0055074 162 0.030
aging GO:0007568 241 0.030
negative regulation of cell death GO:0060548 229 0.029
Rat
hormone secretion GO:0046879 115 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of peptide secretion GO:0002791 82 0.029
tissue development GO:0009888 252 0.029
vitamin biosynthetic process GO:0009110 3 0.028
response to decreased oxygen levels GO:0036293 237 0.028
Rat
central nervous system development GO:0007417 311 0.028
g protein coupled receptor signaling pathway GO:0007186 242 0.027
positive regulation of dopamine secretion GO:0033603 8 0.027
regulation of phosphorylation GO:0042325 248 0.027
vitamin d biosynthetic process GO:0042368 2 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
cell projection organization GO:0030030 302 0.027
fatty acid oxidation GO:0019395 29 0.027
cellular amine metabolic process GO:0044106 38 0.027
cellular potassium ion transport GO:0071804 72 0.026
cellular response to vitamin e GO:0071306 3 0.026
organophosphate metabolic process GO:0019637 370 0.026
carbohydrate metabolic process GO:0005975 130 0.025
amine metabolic process GO:0009308 38 0.025
response to acid chemical GO:0001101 222 0.025
positive regulation of hormone secretion GO:0046887 65 0.025
protein complex biogenesis GO:0070271 263 0.024
insecticide metabolic process GO:0017143 4 0.024
fatty acid derivative metabolic process GO:1901568 38 0.024
organic hydroxy compound transport GO:0015850 77 0.024
regulation of homeostatic process GO:0032844 101 0.024
peristalsis GO:0030432 2 0.024
protein oligomerization GO:0051259 191 0.024
response to monosaccharide GO:0034284 159 0.023
regulation of muscle system process GO:0090257 79 0.023
neurological system process GO:0050877 219 0.023
Rat
multicellular organism growth GO:0035264 1 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
response to tumor necrosis factor GO:0034612 56 0.022
response to cadmium ion GO:0046686 35 0.022
fractalkine metabolic process GO:0050756 3 0.022
b cell activation involved in immune response GO:0002312 1 0.022
behavioral response to nicotine GO:0035095 2 0.022
regulation of immune system process GO:0002682 123 0.022
ion homeostasis GO:0050801 212 0.022
potassium ion transmembrane transport GO:0071805 71 0.022
excretion GO:0007588 24 0.021
vitamin transport GO:0051180 14 0.021
cellular response to stress GO:0033554 269 0.021
Rat
response to hypoxia GO:0001666 231 0.021
Rat
secretion GO:0046903 307 0.021
peptide transport GO:0015833 97 0.021
response to amino acid GO:0043200 75 0.021
response to testosterone GO:0033574 55 0.021
lipid oxidation GO:0034440 30 0.021
regulation of protein metabolic process GO:0051246 289 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
potassium ion transport GO:0006813 97 0.020
macromolecular complex assembly GO:0065003 273 0.020
muscle contraction GO:0006936 88 0.020
Rat
organelle organization GO:0006996 266 0.020
Rat
cellular response to glucocorticoid stimulus GO:0071385 68 0.020
cyclic purine nucleotide metabolic process GO:0052652 62 0.020
insulin secretion GO:0030073 69 0.020
neuron death GO:0070997 127 0.020
Rat
regulation of anatomical structure size GO:0090066 135 0.019
brain development GO:0007420 247 0.019
cellular ketone metabolic process GO:0042180 51 0.019
regulation of hormone secretion GO:0046883 106 0.019
positive regulation of developmental process GO:0051094 283 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
positive regulation of ion transport GO:0043270 94 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
negative regulation of metabolic process GO:0009892 331 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.018
protein heterooligomerization GO:0051291 89 0.018
regulation of catalytic activity GO:0050790 304 0.018
cellular response to external stimulus GO:0071496 118 0.018
regulation of organelle organization GO:0033043 80 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
peptide hormone secretion GO:0030072 84 0.017
regulation of transcription regulatory region dna binding GO:2000677 4 0.017
response to transition metal nanoparticle GO:1990267 122 0.017
regulation of peptide hormone secretion GO:0090276 80 0.017
oxidation reduction process GO:0055114 304 0.017
regulation of peptide transport GO:0090087 87 0.017
fat soluble vitamin biosynthetic process GO:0042362 2 0.017
halogenated hydrocarbon metabolic process GO:0042197 4 0.017
l glutamate import GO:0051938 2 0.016
regulation of metal ion transport GO:0010959 118 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
negative regulation of collagen biosynthetic process GO:0032966 4 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
cytoskeleton organization GO:0007010 111 0.016
gamete generation GO:0007276 124 0.016
regulation of dopamine secretion GO:0014059 15 0.016
organic hydroxy compound biosynthetic process GO:1901617 51 0.016
sequestering of calcium ion GO:0051208 8 0.016
carbohydrate homeostasis GO:0033500 75 0.016
calcium mediated signaling GO:0019722 23 0.015
sexual reproduction GO:0019953 148 0.015
carboxylic acid transport GO:0046942 115 0.015
regulation of striated muscle contraction GO:0006942 21 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
regulation of cell growth GO:0001558 85 0.015
Rat
catecholamine transport GO:0051937 37 0.015
spermatogenesis GO:0007283 99 0.015
response to oxygen levels GO:0070482 265 0.015
Rat
regulation of actin filament based process GO:0032970 42 0.015
epiboly GO:0090504 2 0.015
response to bacterium GO:0009617 200 0.015
cellular alcohol biosynthetic process GO:0044108 2 0.014
behavior GO:0007610 205 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
lipid biosynthetic process GO:0008610 128 0.014
response to cocaine GO:0042220 39 0.014
acid secretion GO:0046717 48 0.014
regulation of cell differentiation GO:0045595 320 0.014
multi organism reproductive process GO:0044703 262 0.014
response to vitamin e GO:0033197 24 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
chemokine metabolic process GO:0050755 3 0.014
immune system process GO:0002376 204 0.014
second messenger mediated signaling GO:0019932 51 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of peptide secretion GO:0002793 52 0.014
cellular response to peptide GO:1901653 133 0.014
Rat
regulation of cell projection organization GO:0031344 175 0.014
negative regulation of molecular function GO:0044092 133 0.014
glucose homeostasis GO:0042593 75 0.014
response to organophosphorus GO:0046683 102 0.014
cellular response to oxygen levels GO:0071453 60 0.014
Rat
cardiac muscle contraction GO:0060048 27 0.013
Rat
icosanoid biosynthetic process GO:0046456 18 0.013
positive regulation of synaptic transmission GO:0050806 62 0.013
unsaturated fatty acid metabolic process GO:0033559 39 0.013
regulation of muscle contraction GO:0006937 53 0.013
micturition GO:0060073 4 0.013
inflammatory response GO:0006954 150 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
immunoglobulin mediated immune response GO:0016064 4 0.013
response to nicotine GO:0035094 51 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
cardiac muscle cell contraction GO:0086003 10 0.013
Rat
positive regulation of gene expression GO:0010628 244 0.013
single organism catabolic process GO:0044712 283 0.013
sequestering of metal ion GO:0051238 9 0.013
mapk cascade GO:0000165 140 0.013
cellular response to nutrient levels GO:0031669 60 0.013
programmed cell death GO:0012501 392 0.013
Rat
lipid storage GO:0019915 1 0.013
dopamine transport GO:0015872 18 0.013
response to hexose GO:0009746 144 0.013
heart development GO:0007507 72 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
negative regulation of cell communication GO:0010648 158 0.013
catechol containing compound metabolic process GO:0009712 19 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
Rat
cellular hormone metabolic process GO:0034754 49 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
Rat
male gamete generation GO:0048232 99 0.012
actin filament depolymerization GO:0030042 3 0.012
regulation of secretion by cell GO:1903530 208 0.012
rho protein signal transduction GO:0007266 11 0.012
positive regulation of isotype switching GO:0045830 1 0.012
vitamin d3 metabolic process GO:0070640 2 0.012
positive regulation of peptide hormone secretion GO:0090277 50 0.012
lipid metabolic process GO:0006629 283 0.012
estrogen biosynthetic process GO:0006703 6 0.012
secondary alcohol metabolic process GO:1902652 2 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
regulation of heart contraction GO:0008016 48 0.012
Rat
response to glucose GO:0009749 136 0.012
leydig cell differentiation GO:0033327 8 0.012
cell migration GO:0016477 197 0.012
response to ethanol GO:0045471 162 0.012
molting cycle GO:0042303 3 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
regulation of transferase activity GO:0051338 123 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
Rat
regulation of catecholamine secretion GO:0050433 32 0.012
multicellular organism reproduction GO:0032504 233 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
Rat
benzene containing compound metabolic process GO:0042537 22 0.012
regulation of molecular function GO:0065009 398 0.012
regulation of insulin secretion GO:0050796 65 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
protein phosphorylation GO:0006468 345 0.011
cellular response to interferon gamma GO:0071346 14 0.011
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.011
circulatory system development GO:0072359 134 0.011
heart morphogenesis GO:0003007 3 0.011
nucleotide metabolic process GO:0009117 279 0.011
monoamine transport GO:0015844 43 0.011
response to corticosterone GO:0051412 40 0.011
renal system process GO:0003014 40 0.011
negative regulation of signaling GO:0023057 157 0.011
regulation of tube size GO:0035150 89 0.011
phospholipid metabolic process GO:0006644 61 0.011
grooming behavior GO:0007625 4 0.011
cellular response to alcohol GO:0097306 87 0.011
dibenzo p dioxin metabolic process GO:0018894 10 0.011
dopamine secretion GO:0014046 15 0.011
estrogen metabolic process GO:0008210 11 0.011
phenol containing compound metabolic process GO:0018958 30 0.011
regulation of immunoglobulin secretion GO:0051023 1 0.011
regulation of neuron projection development GO:0010975 161 0.011
response to external biotic stimulus GO:0043207 221 0.011
response to peptide GO:1901652 292 0.011
Rat
glial cell differentiation GO:0010001 65 0.010
positive regulation of catecholamine secretion GO:0033605 13 0.010
cellular response to tumor necrosis factor GO:0071356 46 0.010
cellular amino acid metabolic process GO:0006520 107 0.010
purine containing compound metabolic process GO:0072521 253 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
response to growth factor GO:0070848 189 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
maternal process involved in female pregnancy GO:0060135 38 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
regulation of ion homeostasis GO:2000021 63 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.010
positive regulation of nervous system development GO:0051962 178 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
protein maturation GO:0051604 68 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
positive regulation of homeostatic process GO:0032846 49 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
epiboly involved in wound healing GO:0090505 2 0.010

Slc9a3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
urinary system disease DOID:18 0 0.052
disease of anatomical entity DOID:7 0 0.052
kidney disease DOID:557 0 0.049
bone disease DOID:0080001 0 0.020
connective tissue disease DOID:65 0 0.020
bone development disease DOID:0080006 0 0.020
musculoskeletal system disease DOID:17 0 0.020
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.017
steroid inherited metabolic disorder DOID:1701 0 0.017
lipid metabolism disorder DOID:3146 0 0.017
congenital adrenal hyperplasia DOID:0050811 0 0.017
nervous system disease DOID:863 0 0.013
central nervous system disease DOID:331 0 0.013