Rattus norvegicus

0 known processes

Ube3a

ubiquitin protein ligase E3A

Ube3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.151
regulation of cellular component organization GO:0051128 368 0.148
gastrulation GO:0007369 2 0.130
positive regulation of transcription dna templated GO:0045893 197 0.088
regulation of rna metabolic process GO:0051252 391 0.080
macromolecular complex subunit organization GO:0043933 339 0.080
protein complex biogenesis GO:0070271 263 0.078
single organism reproductive process GO:0044702 297 0.072
cellular component assembly GO:0022607 360 0.072
transcription dna templated GO:0006351 377 0.070
cellular component biogenesis GO:0044085 368 0.068
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.066
protein complex assembly GO:0006461 263 0.065
nucleic acid templated transcription GO:0097659 379 0.064
reproduction GO:0000003 245 0.063
multicellular organism reproduction GO:0032504 233 0.060
macromolecular complex assembly GO:0065003 273 0.059
multicellular organismal reproductive process GO:0048609 233 0.054
positive regulation of nucleic acid templated transcription GO:1903508 197 0.053
brain development GO:0007420 247 0.051
organophosphate biosynthetic process GO:0090407 143 0.050
head development GO:0060322 247 0.048
male mating behavior GO:0060179 3 0.047
regulation of growth GO:0040008 105 0.047
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.046
cell projection organization GO:0030030 302 0.046
regulation of cell growth GO:0001558 85 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.044
regulation of cell projection organization GO:0031344 175 0.043
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
regulation of developmental growth GO:0048638 45 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.037
programmed cell death GO:0012501 392 0.037
bmp signaling pathway GO:0030509 4 0.037
positive regulation of gene expression GO:0010628 244 0.037
intracellular signal transduction GO:0035556 314 0.037
apoptotic process GO:0006915 381 0.036
rna metabolic process GO:0016070 406 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.036
reproductive process GO:0022414 372 0.035
regulation of nervous system development GO:0051960 264 0.035
circulatory system development GO:0072359 134 0.034
regulation of neuron differentiation GO:0045664 208 0.034
positive regulation of cellular component biogenesis GO:0044089 55 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.031
axis specification GO:0009798 4 0.031
positive regulation of cellular component organization GO:0051130 200 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
mesoderm development GO:0007498 2 0.029
regulation of bmp signaling pathway GO:0030510 2 0.029
protein complex subunit organization GO:0071822 302 0.029
regulation of apoptotic process GO:0042981 335 0.028
formation of primary germ layer GO:0001704 1 0.028
cation homeostasis GO:0055080 195 0.028
cell cell signaling GO:0007267 335 0.028
negative regulation of signal transduction GO:0009968 83 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
rna biosynthetic process GO:0032774 380 0.026
protein homooligomerization GO:0051260 91 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
inorganic ion transmembrane transport GO:0098660 229 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
growth GO:0040007 165 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
gamete generation GO:0007276 124 0.024
embryonic skeletal system development GO:0048706 3 0.024
endocytosis GO:0006897 84 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
developmental growth GO:0048589 100 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
nucleotide metabolic process GO:0009117 279 0.024
tissue development GO:0009888 252 0.023
regulation of cell morphogenesis GO:0022604 77 0.023
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.023
negative regulation of cell communication GO:0010648 158 0.022
protein oligomerization GO:0051259 191 0.022
organelle organization GO:0006996 266 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
neuron differentiation GO:0030182 368 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
ribonucleotide metabolic process GO:0009259 231 0.021
sex differentiation GO:0007548 113 0.021
heart development GO:0007507 72 0.021
actin filament based process GO:0030029 86 0.020
inorganic cation transmembrane transport GO:0098662 202 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
chromosome segregation GO:0007059 2 0.020
synaptic transmission GO:0007268 235 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
purine containing compound metabolic process GO:0072521 253 0.020
heterocycle catabolic process GO:0046700 167 0.019
multicellular organism growth GO:0035264 1 0.019
heart morphogenesis GO:0003007 3 0.019
developmental process involved in reproduction GO:0003006 159 0.019
protein heterooligomerization GO:0051291 89 0.019
positive regulation of developmental process GO:0051094 283 0.019
carboxylic acid metabolic process GO:0019752 289 0.018
cell growth GO:0016049 104 0.018
chemical homeostasis GO:0048878 292 0.018
embryonic pattern specification GO:0009880 1 0.018
phasic smooth muscle contraction GO:0014821 3 0.018
sodium ion transport GO:0006814 82 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
cardiovascular system development GO:0072358 134 0.018
wnt signaling pathway GO:0016055 17 0.018
cytoplasmic transport GO:0016482 115 0.018
negative regulation of gene expression GO:0010629 199 0.018
gonad development GO:0008406 104 0.018
hepatocyte growth factor receptor signaling pathway GO:0048012 1 0.017
sexual reproduction GO:0019953 148 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
regulation of neurogenesis GO:0050767 247 0.017
positive regulation of cell proliferation GO:0008284 249 0.017
digestive system development GO:0055123 41 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
regulation of signal transduction GO:0009966 318 0.017
organic substance catabolic process GO:1901575 316 0.017
spindle organization GO:0007051 2 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
single organism organelle organization GO:1902589 180 0.016
neuron projection development GO:0031175 273 0.016
aging GO:0007568 241 0.016
negative regulation of muscle cell apoptotic process GO:0010656 21 0.016
sympathetic nervous system development GO:0048485 1 0.016
regulation of molecular function GO:0065009 398 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
mesoderm formation GO:0001707 1 0.015
signal release GO:0023061 145 0.015
mammary gland epithelium development GO:0061180 1 0.015
neural crest cell migration GO:0001755 1 0.015
organ formation GO:0048645 3 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
amine metabolic process GO:0009308 38 0.015
epithelium development GO:0060429 96 0.015
positive regulation of molecular function GO:0044093 230 0.015
cell cycle GO:0007049 101 0.014
cellular amine metabolic process GO:0044106 38 0.014
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.014
neural crest cell development GO:0014032 2 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
positive regulation of growth GO:0045927 55 0.014
cell motility GO:0048870 202 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
organ induction GO:0001759 1 0.014
single organism biosynthetic process GO:0044711 342 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
transmembrane transport GO:0055085 412 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
embryo development GO:0009790 49 0.013
negative regulation of signaling GO:0023057 157 0.013
regulation of nucleotide biosynthetic process GO:0030808 47 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
dendrite morphogenesis GO:0048813 43 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
cellular catabolic process GO:0044248 295 0.013
cellular protein complex assembly GO:0043623 44 0.013
camp metabolic process GO:0046058 63 0.013
intracellular transport GO:0046907 185 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
connective tissue development GO:0061448 33 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
digestive tract development GO:0048565 39 0.013
regulation of neuron projection development GO:0010975 161 0.013
organic acid metabolic process GO:0006082 292 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
homeostatic process GO:0042592 331 0.012
regulation of programmed cell death GO:0043067 341 0.012
spermatogenesis GO:0007283 99 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
protein phosphorylation GO:0006468 345 0.012
negative regulation of metabolic process GO:0009892 331 0.012
development of primary sexual characteristics GO:0045137 107 0.012
positive regulation of nervous system development GO:0051962 178 0.012
ion transmembrane transport GO:0034220 365 0.012
response to growth factor GO:0070848 189 0.012
axis elongation GO:0003401 2 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
male gamete generation GO:0048232 99 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
camera type eye morphogenesis GO:0048593 2 0.012
camera type eye development GO:0043010 48 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
macromolecule localization GO:0033036 252 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
organophosphate metabolic process GO:0019637 370 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.012
positive regulation of brown fat cell proliferation GO:0070349 1 0.012
membrane organization GO:0061024 94 0.012
central nervous system development GO:0007417 311 0.012
regulation of cell development GO:0060284 263 0.011
mesoderm morphogenesis GO:0048332 1 0.011
actin cytoskeleton organization GO:0030036 73 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.011
muscle cell apoptotic process GO:0010657 30 0.011
axonogenesis GO:0007409 71 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
secretion GO:0046903 307 0.011
sodium ion transmembrane transport GO:0035725 67 0.011
wound healing GO:0042060 122 0.011
positive regulation of synaptic growth at neuromuscular junction GO:0045887 1 0.011
organ growth GO:0035265 24 0.011
anterior posterior pattern specification GO:0009952 1 0.011
hormone secretion GO:0046879 115 0.011
specification of organ identity GO:0010092 2 0.010
pyrimidine nucleobase catabolic process GO:0006208 3 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
cell cycle process GO:0022402 57 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
alcohol biosynthetic process GO:0046165 38 0.010
regulation of cell size GO:0008361 37 0.010
synaptic growth at neuromuscular junction GO:0051124 1 0.010
saliva secretion GO:0046541 3 0.010

Ube3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
cancer DOID:162 0 0.030
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
gastrointestinal system cancer DOID:3119 0 0.013
urinary system disease DOID:18 0 0.011