Saccharomyces cerevisiae

107 known processes

PKH2 (YOL100W)

Pkh2p

PKH2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell wall organization or biogenesis GO:0071554 190 0.806
fungal type cell wall organization or biogenesis GO:0071852 169 0.670
single organism signaling GO:0044700 208 0.662
heterocycle catabolic process GO:0046700 494 0.513
fungal type cell wall organization GO:0031505 145 0.432
multi organism reproductive process GO:0044703 216 0.427
autophagy GO:0006914 106 0.423
multi organism process GO:0051704 233 0.405
reproductive process in single celled organism GO:0022413 145 0.361
nucleobase containing compound catabolic process GO:0034655 479 0.357
ascospore formation GO:0030437 107 0.349
signal transduction GO:0007165 208 0.339
sporulation GO:0043934 132 0.334
reproductive process GO:0022414 248 0.326
regulation of cellular catabolic process GO:0031329 195 0.324
organonitrogen compound catabolic process GO:1901565 404 0.321
sexual reproduction GO:0019953 216 0.318
phosphorylation GO:0016310 291 0.302
cellular nitrogen compound catabolic process GO:0044270 494 0.294
developmental process involved in reproduction GO:0003006 159 0.294
external encapsulating structure organization GO:0045229 146 0.283
single organism reproductive process GO:0044702 159 0.267
organelle assembly GO:0070925 118 0.256
cellular response to dna damage stimulus GO:0006974 287 0.254
Fly
aromatic compound catabolic process GO:0019439 491 0.248
ribose phosphate metabolic process GO:0019693 384 0.246
regulation of cellular component organization GO:0051128 334 0.243
Human Fly
purine nucleoside catabolic process GO:0006152 330 0.242
regulation of cell growth GO:0001558 29 0.240
Fly
mitotic sister chromatid segregation GO:0000070 85 0.230
cellular response to chemical stimulus GO:0070887 315 0.220
Human
mitotic cell cycle phase transition GO:0044772 141 0.201
sexual sporulation GO:0034293 113 0.199
positive regulation of phosphorus metabolic process GO:0010562 147 0.194
Human
cellular response to organic substance GO:0071310 159 0.194
Human
chromosome segregation GO:0007059 159 0.193
double strand break repair GO:0006302 105 0.186
purine containing compound metabolic process GO:0072521 400 0.183
metal ion homeostasis GO:0055065 79 0.181
Human
negative regulation of signal transduction GO:0009968 30 0.180
Human Mouse
purine containing compound catabolic process GO:0072523 332 0.179
organic cyclic compound catabolic process GO:1901361 499 0.179
reproduction of a single celled organism GO:0032505 191 0.174
endosomal transport GO:0016197 86 0.173
protein phosphorylation GO:0006468 197 0.170
meiotic cell cycle GO:0051321 272 0.169
negative regulation of cell communication GO:0010648 33 0.166
Human Mouse
ion homeostasis GO:0050801 118 0.162
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 327 0.159
regulation of catabolic process GO:0009894 199 0.159
chemical homeostasis GO:0048878 137 0.153
Human
negative regulation of cellular metabolic process GO:0031324 407 0.151
Human
cell growth GO:0016049 89 0.151
Fly
establishment of protein localization to organelle GO:0072594 278 0.149
cellular cation homeostasis GO:0030003 100 0.147
Human
cell development GO:0048468 107 0.147
Mouse
cell surface receptor signaling pathway GO:0007166 38 0.146
Human Fly
regulation of anatomical structure size GO:0090066 50 0.145
Fly
intracellular signal transduction GO:0035556 112 0.143
regulation of phosphorus metabolic process GO:0051174 230 0.142
Human
nucleoside triphosphate catabolic process GO:0009143 329 0.140
sister chromatid segregation GO:0000819 93 0.135
nucleoside metabolic process GO:0009116 394 0.130
growth of unicellular organism as a thread of attached cells GO:0070783 105 0.127
cell communication GO:0007154 345 0.126
ribonucleotide metabolic process GO:0009259 377 0.125
cellular response to starvation GO:0009267 90 0.125
purine nucleotide catabolic process GO:0006195 328 0.123
cellular ion homeostasis GO:0006873 112 0.122
Human
anatomical structure formation involved in morphogenesis GO:0048646 136 0.120
regulation of dna metabolic process GO:0051052 100 0.119
developmental process GO:0032502 261 0.119
Mouse Worm Fly
cellular component assembly involved in morphogenesis GO:0010927 73 0.119
nuclear division GO:0000280 263 0.118
single organism catabolic process GO:0044712 619 0.117
response to organic substance GO:0010033 182 0.117
Human
ribonucleoside triphosphate catabolic process GO:0009203 327 0.117
sporulation resulting in formation of a cellular spore GO:0030435 129 0.116
protein complex assembly GO:0006461 302 0.112
organophosphate catabolic process GO:0046434 338 0.109
atp catabolic process GO:0006200 224 0.109
nucleoside triphosphate metabolic process GO:0009141 364 0.107
peptidyl amino acid modification GO:0018193 116 0.105
Human
cation homeostasis GO:0055080 105 0.105
Human
nucleoside catabolic process GO:0009164 335 0.104
response to abiotic stimulus GO:0009628 159 0.103
Mouse
purine ribonucleoside monophosphate catabolic process GO:0009169 224 0.101
multi organism cellular process GO:0044764 120 0.100
rna catabolic process GO:0006401 118 0.100
mitotic cell cycle GO:0000278 306 0.100
mrna 3 end processing GO:0031124 54 0.098
cell cycle phase transition GO:0044770 144 0.096
regulation of growth GO:0040008 50 0.091
Fly
negative regulation of response to stimulus GO:0048585 40 0.090
Human Mouse
purine ribonucleotide metabolic process GO:0009150 372 0.090
negative regulation of macromolecule metabolic process GO:0010605 375 0.088
Human
regulation of response to stimulus GO:0048583 157 0.087
Human Mouse Worm
meiotic cell cycle process GO:1903046 229 0.086
signaling GO:0023052 208 0.086
regulation of biological quality GO:0065008 391 0.085
Human Fly
response to heat GO:0009408 69 0.085
cell wall biogenesis GO:0042546 93 0.084
sulfur compound metabolic process GO:0006790 95 0.083
purine ribonucleotide catabolic process GO:0009154 327 0.082
glycosyl compound catabolic process GO:1901658 335 0.081
ribonucleoside catabolic process GO:0042454 332 0.081
filamentous growth GO:0030447 124 0.079
cellular metal ion homeostasis GO:0006875 78 0.075
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 409 0.075
purine ribonucleoside catabolic process GO:0046130 330 0.075
organelle fission GO:0048285 272 0.074
growth GO:0040007 157 0.074
Fly
nucleoside phosphate catabolic process GO:1901292 331 0.074
purine nucleoside triphosphate catabolic process GO:0009146 329 0.074
dna recombination GO:0006310 172 0.072
organophosphate metabolic process GO:0019637 597 0.072
homeostatic process GO:0042592 227 0.071
Human
ribonucleoside monophosphate catabolic process GO:0009158 224 0.070
cellular developmental process GO:0048869 191 0.069
Mouse
purine nucleotide metabolic process GO:0006163 376 0.069
cellular component morphogenesis GO:0032989 97 0.068
regulation of molecular function GO:0065009 320 0.068
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 295 0.068
nucleobase containing small molecule metabolic process GO:0055086 491 0.067
conjugation with cellular fusion GO:0000747 106 0.066
carbohydrate derivative metabolic process GO:1901135 549 0.066
purine ribonucleoside triphosphate metabolic process GO:0009205 354 0.065
macroautophagy GO:0016236 55 0.065
positive regulation of hydrolase activity GO:0051345 112 0.064
Human
mitotic cell cycle process GO:1903047 294 0.064
purine nucleoside metabolic process GO:0042278 380 0.063
regulation of metal ion transport GO:0010959 2 0.062
Human
macromolecule catabolic process GO:0009057 383 0.062
regulation of cellular component biogenesis GO:0044087 112 0.062
cellular homeostasis GO:0019725 138 0.062
Human
response to organic cyclic compound GO:0014070 1 0.061
regulation of filamentous growth GO:0010570 38 0.060
purine ribonucleoside monophosphate metabolic process GO:0009167 262 0.060
oxoacid metabolic process GO:0043436 351 0.058
response to nutrient levels GO:0031667 150 0.057
invasive growth in response to glucose limitation GO:0001403 61 0.056
negative regulation of transcription from rna polymerase ii promoter GO:0000122 137 0.056
cell differentiation GO:0030154 161 0.056
Mouse
cell wall organization GO:0071555 146 0.056
cellular response to nutrient levels GO:0031669 144 0.054
purine nucleoside monophosphate catabolic process GO:0009128 224 0.054
late endosome to vacuole transport via multivesicular body sorting pathway GO:0032511 26 0.053
death GO:0016265 30 0.052
Human Mouse Fly
macromolecular complex disassembly GO:0032984 80 0.052
nucleoside monophosphate catabolic process GO:0009125 224 0.051
carboxylic acid metabolic process GO:0019752 338 0.051
meiotic nuclear division GO:0007126 163 0.050
carbohydrate derivative catabolic process GO:1901136 339 0.050
regulation of carbohydrate biosynthetic process GO:0043255 31 0.049
purine ribonucleoside metabolic process GO:0046128 380 0.049
negative regulation of intracellular signal transduction GO:1902532 27 0.048
filamentous growth of a population of unicellular organisms GO:0044182 109 0.047
anatomical structure morphogenesis GO:0009653 160 0.046
Fly
regulation of glucose metabolic process GO:0010906 27 0.046
regulation of protein metabolic process GO:0051246 237 0.045
Human
ribonucleoprotein complex subunit organization GO:0071826 152 0.045
response to pheromone GO:0019236 92 0.044
response to extracellular stimulus GO:0009991 156 0.044
chromatin remodeling GO:0006338 80 0.044
cell aging GO:0007569 70 0.044
positive regulation of catabolic process GO:0009896 135 0.043
conjugation GO:0000746 107 0.043
g1 s transition of mitotic cell cycle GO:0000082 64 0.043
regulation of mitotic cell cycle GO:0007346 107 0.043
organic acid metabolic process GO:0006082 352 0.043
regulation of localization GO:0032879 127 0.043
Human Mouse
anatomical structure development GO:0048856 160 0.042
Mouse Fly
negative regulation of cellular biosynthetic process GO:0031327 312 0.042
positive regulation of cellular component organization GO:0051130 116 0.042
Human
establishment of protein localization GO:0045184 367 0.042
Human
mitotic nuclear division GO:0007067 131 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 289 0.042
endocytosis GO:0006897 90 0.042
Yeast
cellular response to external stimulus GO:0071496 150 0.041
actin filament based process GO:0030029 104 0.038
sexual sporulation resulting in formation of a cellular spore GO:0043935 113 0.038
negative regulation of macromolecule biosynthetic process GO:0010558 291 0.038
protein transport GO:0015031 345 0.038
response to chemical GO:0042221 390 0.038
Human Worm
positive regulation of gene expression GO:0010628 321 0.038
positive regulation of purine nucleotide catabolic process GO:0033123 97 0.037
atp metabolic process GO:0046034 251 0.037
mrna processing GO:0006397 185 0.036
endosome transport via multivesicular body sorting pathway GO:0032509 27 0.036
cellular chemical homeostasis GO:0055082 123 0.036
Human
nuclear transcribed mrna catabolic process GO:0000956 89 0.036
regulation of phosphate metabolic process GO:0019220 230 0.036
Human
aging GO:0007568 71 0.035
vesicle mediated transport GO:0016192 335 0.035
Yeast Mouse
positive regulation of catalytic activity GO:0043085 178 0.035
Human
cell cycle g1 s phase transition GO:0044843 64 0.035
negative regulation of cellular component organization GO:0051129 109 0.035
regulation of cellular component size GO:0032535 50 0.035
Fly
nucleoside monophosphate metabolic process GO:0009123 267 0.034
organic hydroxy compound metabolic process GO:1901615 125 0.034
positive regulation of translation GO:0045727 34 0.034
negative regulation of protein metabolic process GO:0051248 85 0.033
Human
regulation of cell division GO:0051302 113 0.033
cellular response to extracellular stimulus GO:0031668 150 0.033
ribonucleoside metabolic process GO:0009119 389 0.033
positive regulation of nucleotide catabolic process GO:0030813 97 0.033
purine nucleoside triphosphate metabolic process GO:0009144 356 0.033
ribonucleotide catabolic process GO:0009261 327 0.033
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 44 0.032
programmed cell death GO:0012501 30 0.032
Human Mouse Fly
protein targeting GO:0006605 272 0.031
single organism developmental process GO:0044767 258 0.031
Mouse Worm Fly
ion transport GO:0006811 274 0.031
Human
regulation of mitotic cell cycle phase transition GO:1901990 68 0.031
positive regulation of molecular function GO:0044093 185 0.030
Human
positive regulation of cellular catabolic process GO:0031331 128 0.030
rna 3 end processing GO:0031123 88 0.029
regulation of cell cycle phase transition GO:1901987 70 0.029
establishment of protein localization to membrane GO:0090150 99 0.029
Human
regulation of dna replication GO:0006275 51 0.029
cellular amino acid metabolic process GO:0006520 225 0.029
protein localization to membrane GO:0072657 102 0.029
Human
regulation of cell communication GO:0010646 124 0.029
Human Mouse
carbohydrate biosynthetic process GO:0016051 82 0.029
negative regulation of signaling GO:0023057 30 0.028
Human Mouse
vacuolar transport GO:0007034 145 0.028
regulation of cytoskeleton organization GO:0051493 63 0.028
mitochondrion organization GO:0007005 261 0.028
regulation of purine nucleotide catabolic process GO:0033121 106 0.028
regulation of chromosome organization GO:0033044 66 0.027
non recombinational repair GO:0000726 33 0.027
translation GO:0006412 230 0.027
positive regulation of kinase activity GO:0033674 24 0.027
Human
sphingolipid biosynthetic process GO:0030148 29 0.026
regulation of growth of unicellular organism as a thread of attached cells GO:0070784 31 0.026
cellular amide metabolic process GO:0043603 59 0.026
cellular macromolecule catabolic process GO:0044265 363 0.026
regulation of proteasomal protein catabolic process GO:0061136 34 0.026
cellular lipid metabolic process GO:0044255 229 0.025
cellular response to abiotic stimulus GO:0071214 62 0.025
fungal type cell wall biogenesis GO:0009272 80 0.025
intracellular protein transport GO:0006886 319 0.025
positive regulation of macromolecule metabolic process GO:0010604 394 0.024
Human
regulation of cellular ketone metabolic process GO:0010565 42 0.024
cellular ketone metabolic process GO:0042180 63 0.024
regulation of signal transduction GO:0009966 114 0.024
Human Mouse
positive regulation of nucleotide metabolic process GO:0045981 101 0.024
pseudohyphal growth GO:0007124 75 0.024
positive regulation of fatty acid beta oxidation GO:0032000 3 0.024
actin filament organization GO:0007015 56 0.024
chromatin organization GO:0006325 242 0.023
regulation of phosphorylation GO:0042325 86 0.022
Human
regulation of carbohydrate metabolic process GO:0006109 43 0.022
posttranscriptional regulation of gene expression GO:0010608 115 0.022
apoptotic process GO:0006915 30 0.021
Human Mouse Fly
regulation of lipid metabolic process GO:0019216 45 0.021
positive regulation of cellular biosynthetic process GO:0031328 336 0.021
negative regulation of chromosome organization GO:2001251 39 0.021
nucleoside phosphate metabolic process GO:0006753 458 0.020
regulation of catalytic activity GO:0050790 307 0.020
Human
regulation of nucleoside metabolic process GO:0009118 106 0.020
regulation of actin cytoskeleton organization GO:0032956 31 0.020
cellular carbohydrate biosynthetic process GO:0034637 49 0.020
replicative cell aging GO:0001302 46 0.020
negative regulation of gene expression GO:0010629 312 0.020
mrna metabolic process GO:0016071 269 0.019
mrna catabolic process GO:0006402 93 0.019
establishment or maintenance of cell polarity GO:0007163 96 0.019
regulation of lipid catabolic process GO:0050994 4 0.019
dna repair GO:0006281 236 0.019
regulation of cellular response to stress GO:0080135 50 0.019
regulation of gtp catabolic process GO:0033124 84 0.019
regulation of translation GO:0006417 89 0.019
positive regulation of lipid catabolic process GO:0050996 4 0.019
regulation of transport GO:0051049 85 0.018
Human Mouse
nucleotide catabolic process GO:0009166 330 0.018
protein localization to organelle GO:0033365 337 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 325 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
Human
microtubule based process GO:0007017 117 0.018
ascospore wall assembly GO:0030476 52 0.017
regulation of transcription involved in g1 s transition of mitotic cell cycle GO:0000083 27 0.017
regulation of nucleotide catabolic process GO:0030811 106 0.017
positive regulation of mitotic cell cycle GO:0045931 16 0.017
ribonucleoside monophosphate metabolic process GO:0009161 265 0.017
nucleotide metabolic process GO:0009117 453 0.017
positive regulation of cell death GO:0010942 3 0.017
double strand break repair via nonhomologous end joining GO:0006303 27 0.017
regulation of cell size GO:0008361 30 0.017
Fly
glycosyl compound metabolic process GO:1901657 398 0.017
late endosome to vacuole transport GO:0045324 42 0.017
regulation of intracellular signal transduction GO:1902531 78 0.017
Human
dna dependent dna replication GO:0006261 115 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
dna conformation change GO:0071103 98 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 300 0.016
membrane organization GO:0061024 276 0.016
Human
negative regulation of organelle organization GO:0010639 103 0.016
maintenance of location GO:0051235 66 0.016
cell division GO:0051301 205 0.016
mitotic cytokinetic process GO:1902410 45 0.016
regulation of cell cycle GO:0051726 195 0.016
regulation of purine nucleotide metabolic process GO:1900542 109 0.015
membrane lipid metabolic process GO:0006643 67 0.015
positive regulation of intracellular transport GO:0032388 4 0.015
Human
establishment of protein localization to vacuole GO:0072666 91 0.015
cellular response to pheromone GO:0071444 88 0.015
carbon catabolite activation of transcription GO:0045991 26 0.015
regulation of protein modification process GO:0031399 110 0.015
Human
negative regulation of phosphate metabolic process GO:0045936 49 0.015
Human
negative regulation of biosynthetic process GO:0009890 312 0.015
regulation of cell wall organization or biogenesis GO:1903338 18 0.014
membrane lipid biosynthetic process GO:0046467 54 0.014
ribonucleoprotein complex assembly GO:0022618 143 0.014
lipid catabolic process GO:0016042 33 0.014
positive regulation of biosynthetic process GO:0009891 336 0.014
positive regulation of ras gtpase activity GO:0032320 41 0.014
sphingolipid metabolic process GO:0006665 41 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 100 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 252 0.014
metal ion transport GO:0030001 75 0.014
Human
negative regulation of nucleic acid templated transcription GO:1903507 260 0.014
dephosphorylation GO:0016311 127 0.014
response to starvation GO:0042594 96 0.013
regulation of organelle organization GO:0033043 243 0.013
ras protein signal transduction GO:0007265 29 0.013
response to oxidative stress GO:0006979 99 0.013
protein complex biogenesis GO:0070271 314 0.013
regulation of cellular carbohydrate metabolic process GO:0010675 41 0.013
purine nucleoside monophosphate metabolic process GO:0009126 262 0.013
negative regulation of rna biosynthetic process GO:1902679 260 0.013
chromatin modification GO:0016568 200 0.013
cellular component disassembly GO:0022411 86 0.013
cellular response to oxygen containing compound GO:1901701 43 0.013
Human
regulation of cellular protein metabolic process GO:0032268 232 0.012
Human
spindle pole body organization GO:0051300 33 0.012
response to temperature stimulus GO:0009266 74 0.012
positive regulation of phosphorylation GO:0042327 33 0.012
Human
response to salt stress GO:0009651 34 0.012
cellular component movement GO:0006928 20 0.012
Human Mouse
regulation of ras gtpase activity GO:0032318 41 0.012
ethanol catabolic process GO:0006068 1 0.012
transmembrane transport GO:0055085 349 0.012
regulation of fatty acid beta oxidation GO:0031998 3 0.012
phospholipid metabolic process GO:0006644 125 0.012
rrna metabolic process GO:0016072 244 0.012
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 27 0.012
cytokinesis GO:0000910 92 0.012
cellular response to freezing GO:0071497 4 0.012
regulation of signaling GO:0023051 119 0.012
Human Mouse
cellular modified amino acid metabolic process GO:0006575 51 0.012
cellular polysaccharide metabolic process GO:0044264 55 0.012
glycerolipid metabolic process GO:0046486 108 0.012
positive regulation of transcription from rna polymerase ii promoter in response to nitrosative stress GO:0061403 2 0.012
positive regulation of sulfite transport GO:1900072 1 0.012
cellular lipid catabolic process GO:0044242 33 0.012
negative regulation of transcription dna templated GO:0045892 258 0.012
rho protein signal transduction GO:0007266 12 0.011
negative regulation of cell cycle GO:0045786 91 0.011
response to oxygen containing compound GO:1901700 61 0.011
Human
positive regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0036091 3 0.011
cytoskeleton organization GO:0007010 230 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 412 0.011
positive regulation of gtpase activity GO:0043547 80 0.011
protein processing GO:0016485 64 0.011
negative regulation of catabolic process GO:0009895 43 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 30 0.011
lipid modification GO:0030258 37 0.011
amine metabolic process GO:0009308 51 0.011
gtp catabolic process GO:0006184 107 0.011
regulation of gene expression epigenetic GO:0040029 147 0.011
mitotic spindle assembly checkpoint GO:0007094 23 0.011
cellular response to oxidative stress GO:0034599 94 0.011
positive regulation of cell cycle process GO:0090068 31 0.011
response to acid chemical GO:0001101 19 0.010
positive regulation of transcription from rna polymerase ii promoter in response to glucose starvation GO:0061406 2 0.010
rna localization GO:0006403 112 0.010
protein targeting to vacuole GO:0006623 91 0.010
regulation of response to drug GO:2001023 3 0.010
regulation of ras protein signal transduction GO:0046578 47 0.010
positive regulation of fatty acid oxidation GO:0046321 3 0.010
regulation of polysaccharide metabolic process GO:0032881 15 0.010
nitrogen compound transport GO:0071705 212 0.010
organic acid biosynthetic process GO:0016053 152 0.010
regulation of fatty acid oxidation GO:0046320 3 0.010
regulation of mitosis GO:0007088 65 0.010

PKH2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
disease of cellular proliferation DOID:14566 0 0.011