Danio rerio

131 known processes

notch3

notch homolog 3

(Aliases: fa14b08,wu:fa14b08,notch5)

notch3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel development GO:0001568 246 0.999
blood vessel morphogenesis GO:0048514 216 0.998
vasculature development GO:0001944 278 0.995
sensory organ development GO:0007423 393 0.994
Fly
axon guidance GO:0007411 86 0.994
Fly
hemopoiesis GO:0030097 183 0.992
Fly
localization of cell GO:0051674 244 0.992
Fly
cell motility GO:0048870 244 0.989
Fly
sprouting angiogenesis GO:0002040 53 0.987
regulation of nitrogen compound metabolic process GO:0051171 251 0.987
Rat Fly
ameboidal type cell migration GO:0001667 143 0.986
Fly
neuronal stem cell maintenance GO:0097150 2 0.986
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.985
regulation of metabolic process GO:0019222 359 0.985
Rat Fly
endothelial cell proliferation GO:0001935 11 0.983
regulation of neurogenesis GO:0050767 87 0.979
embryonic organ development GO:0048568 381 0.977
Zebrafish Fly
patterning of blood vessels GO:0001569 15 0.975
regulation of rna metabolic process GO:0051252 224 0.975
Rat Fly
regulation of multicellular organismal development GO:2000026 223 0.974
radial glial cell differentiation GO:0060019 2 0.968
Zebrafish
branching morphogenesis of an epithelial tube GO:0048754 15 0.964
neural tube development GO:0021915 62 0.962
regulation of primary metabolic process GO:0080090 311 0.958
Rat Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.953
Rat Fly
organic cyclic compound metabolic process GO:1901360 301 0.950
Rat Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.950
glial cell differentiation GO:0010001 42 0.950
regulation of nucleic acid templated transcription GO:1903506 213 0.948
Rat Fly
regulation of epithelial cell proliferation GO:0050678 3 0.941
nitrogen compound metabolic process GO:0006807 319 0.938
Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.933
Rat Fly
cellular component movement GO:0006928 335 0.927
Fly
immune system development GO:0002520 191 0.925
Fly
cardiac cell fate commitment GO:0060911 1 0.925
Fly
sensory organ morphogenesis GO:0090596 200 0.923
Fly
angiogenesis GO:0001525 158 0.918
Mouse
cell morphogenesis GO:0000902 289 0.918
regulation of multicellular organismal process GO:0051239 277 0.913
mechanosensory lateral line system development GO:0048881 49 0.909
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.909
Rat Fly
gene expression GO:0010467 252 0.907
Rat Fly
chemotaxis GO:0006935 104 0.905
Fly
camera type eye development GO:0043010 222 0.905
morphogenesis of an epithelium GO:0002009 333 0.901
Fly
stem cell maintenance GO:0019827 4 0.897
somatic stem cell maintenance GO:0035019 1 0.897
digestive tract development GO:0048565 265 0.892
Zebrafish Worm Fly
negative regulation of epithelial cell migration GO:0010633 1 0.888
hematopoietic or lymphoid organ development GO:0048534 191 0.888
Fly
eye morphogenesis GO:0048592 144 0.887
Fly
regulation of developmental process GO:0050793 247 0.882
tube morphogenesis GO:0035239 349 0.881
Zebrafish Fly
neuromast development GO:0048884 46 0.876
morphogenesis of a branching epithelium GO:0061138 16 0.876
regulation of biological quality GO:0065008 263 0.875
signal transduction GO:0007165 455 0.874
epithelial cell differentiation GO:0030855 116 0.871
Fly
biological adhesion GO:0022610 40 0.871
Fly
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.868
aromatic compound biosynthetic process GO:0019438 217 0.868
Rat Fly
heart development GO:0007507 313 0.868
Fly
glial cell development GO:0021782 20 0.867
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.866
Rat Fly
blood vessel endothelial cell migration GO:0043534 18 0.864
regulation of biosynthetic process GO:0009889 250 0.863
Rat Fly
hepaticobiliary system development GO:0061008 98 0.859
forebrain development GO:0030900 96 0.857
lateral line system development GO:0048925 76 0.853
eye development GO:0001654 277 0.847
Fly
brain development GO:0007420 293 0.841
regulation of macromolecule biosynthetic process GO:0010556 225 0.836
Rat Fly
nephron tubule morphogenesis GO:0072078 1 0.836
morphogenesis of a branching structure GO:0001763 21 0.829
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.827
nucleic acid templated transcription GO:0097659 181 0.812
Rat Fly
inner ear development GO:0048839 126 0.808
cell morphogenesis involved in differentiation GO:0000904 195 0.801
glial cell proliferation GO:0014009 4 0.800
organelle organization GO:0006996 227 0.797
Worm Fly
regulation of endothelial cell proliferation GO:0001936 1 0.795
positive regulation of endothelial cell proliferation GO:0001938 1 0.794
negative regulation of biological process GO:0048519 304 0.793
single organism reproductive process GO:0044702 40 0.788
Worm Fly
neuron development GO:0048666 262 0.788
neuron projection guidance GO:0097485 86 0.788
Fly
venous blood vessel development GO:0060841 9 0.786
epithelial cell development GO:0002064 42 0.785
Fly
negative regulation of endothelial cell migration GO:0010596 1 0.784
generation of neurons GO:0048699 385 0.773
stem cell proliferation GO:0072089 4 0.760
epithelial tube morphogenesis GO:0060562 148 0.747
Fly
cellular macromolecule metabolic process GO:0044260 391 0.745
Rat Fly
cellular aromatic compound metabolic process GO:0006725 295 0.745
Rat Fly
regulation of nervous system development GO:0051960 90 0.739
actin filament based process GO:0030029 64 0.734
Fly
endothelial cell migration GO:0043542 19 0.727
negative regulation of gliogenesis GO:0014014 1 0.724
mesenchymal cell development GO:0014031 78 0.723
nephron epithelium morphogenesis GO:0072088 1 0.721
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.720
Fly
vasculogenesis GO:0001570 41 0.716
epithelial cell morphogenesis GO:0003382 2 0.715
regulation of anatomical structure morphogenesis GO:0022603 130 0.711
Zebrafish Fly
oligodendrocyte differentiation GO:0048709 23 0.709
regulation of macromolecule metabolic process GO:0060255 317 0.699
Rat Fly
organic substance biosynthetic process GO:1901576 289 0.692
Rat Fly
skin development GO:0043588 54 0.689
positive regulation of notch signaling pathway GO:0045747 3 0.687
Fly
neuron differentiation GO:0030182 353 0.677
rna biosynthetic process GO:0032774 181 0.674
Rat Fly
response to stress GO:0006950 263 0.669
Zebrafish Rat
camera type eye morphogenesis GO:0048593 108 0.659
digestive tract morphogenesis GO:0048546 231 0.658
Zebrafish Fly
positive regulation of nucleic acid templated transcription GO:1903508 57 0.649
Fly
regulation of transcription dna templated GO:0006355 213 0.648
Rat Fly
nucleic acid metabolic process GO:0090304 244 0.647
Rat Fly
negative regulation of multicellular organismal process GO:0051241 69 0.647
gliogenesis GO:0042063 45 0.644
reproduction GO:0000003 40 0.642
Worm Fly
positive regulation of neural precursor cell proliferation GO:2000179 1 0.641
regulation of gene expression GO:0010468 265 0.641
Rat Fly
axonogenesis GO:0007409 152 0.640
cellular protein metabolic process GO:0044267 129 0.636
Fly
cell migration GO:0016477 237 0.635
Fly
renal tubule morphogenesis GO:0061333 1 0.632
Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.631
negative regulation of developmental process GO:0051093 65 0.627
single organism organelle organization GO:1902589 199 0.627
Fly
heterocycle biosynthetic process GO:0018130 215 0.626
Rat Fly
positive regulation of metabolic process GO:0009893 108 0.622
Fly
chordate embryonic development GO:0043009 271 0.620
nucleobase containing compound biosynthetic process GO:0034654 205 0.620
Rat Fly
kidney development GO:0001822 92 0.620
epithelial cell proliferation GO:0050673 17 0.615
Fly
cellular component morphogenesis GO:0032989 336 0.607
epithelial cell migration GO:0010631 25 0.603
Fly
somitogenesis GO:0001756 87 0.603
Zebrafish
hypochord development GO:0055016 3 0.601
Zebrafish
hair cell differentiation GO:0035315 32 0.600
regulation of glial cell differentiation GO:0045685 4 0.596
positive regulation of epithelial cell differentiation GO:0030858 2 0.595
cellular macromolecule biosynthetic process GO:0034645 224 0.592
Rat Fly
myeloid cell differentiation GO:0030099 86 0.591
transcription from rna polymerase ii promoter GO:0006366 80 0.590
Fly
developmental growth GO:0048589 166 0.585
Zebrafish Rat
enzyme linked receptor protein signaling pathway GO:0007167 106 0.580
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.578
Fly
heterocycle metabolic process GO:0046483 290 0.576
Rat Fly
protein import into nucleus GO:0006606 3 0.574
neuroblast proliferation GO:0007405 2 0.570
taxis GO:0042330 109 0.569
Fly
nephron epithelium development GO:0072009 16 0.557
digestive system development GO:0055123 289 0.556
Zebrafish Worm Fly
hypothalamus cell differentiation GO:0021979 4 0.554
rna metabolic process GO:0016070 219 0.550
Rat Fly
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.550
Zebrafish
regulation of angiogenesis GO:0045765 26 0.546
negative regulation of cellular process GO:0048523 283 0.544
urogenital system development GO:0001655 97 0.541
transcription dna templated GO:0006351 181 0.540
Rat Fly
renal tubule development GO:0061326 5 0.539
Fly
embryonic organ morphogenesis GO:0048562 274 0.535
negative regulation of cell development GO:0010721 26 0.526
regulation of embryonic development GO:0045995 47 0.525
Zebrafish
response to organic substance GO:0010033 153 0.525
posterior lateral line system development GO:0048915 46 0.519
negative regulation of cell migration GO:0030336 17 0.518
regulation of neural precursor cell proliferation GO:2000177 3 0.512
positive regulation of stem cell proliferation GO:2000648 1 0.512
myelination GO:0042552 18 0.512
nephron development GO:0072006 31 0.511
Mouse
head development GO:0060322 303 0.508
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.508
connective tissue development GO:0061448 99 0.497
Zebrafish
sensory system development GO:0048880 76 0.496
regulation of cellular biosynthetic process GO:0031326 245 0.495
Rat Fly
regulation of vasculature development GO:1901342 33 0.493
epithelium migration GO:0090132 25 0.492
Fly
positive regulation of rna metabolic process GO:0051254 59 0.486
Fly
tissue migration GO:0090130 37 0.484
Fly
single organism nuclear import GO:1902593 3 0.473
regulation of oligodendrocyte differentiation GO:0048713 1 0.472
positive regulation of biological process GO:0048518 253 0.469
Zebrafish Mouse Fly
neuroblast differentiation GO:0014016 1 0.469
Fly
cellular biosynthetic process GO:0044249 286 0.464
Rat Fly
mesoderm development GO:0007498 88 0.462
Zebrafish Fly
morphogenesis of embryonic epithelium GO:0016331 30 0.460
axon ensheathment GO:0008366 18 0.457
peripheral nervous system development GO:0007422 55 0.453
axon development GO:0061564 166 0.449
positive regulation of cellular metabolic process GO:0031325 94 0.448
Fly
locomotion GO:0040011 313 0.448
Worm Fly
positive regulation of biosynthetic process GO:0009891 68 0.447
Fly
regulation of inner ear receptor cell differentiation GO:2000980 1 0.447
female sex differentiation GO:0046660 4 0.445
midbrain development GO:0030901 28 0.443
endodermal cell fate commitment GO:0001711 18 0.434
Zebrafish
regulation of stem cell differentiation GO:2000736 4 0.434
Fly
lateral inhibition GO:0046331 1 0.432
Fly
mesodermal cell fate commitment GO:0001710 14 0.429
Zebrafish
muscle fiber development GO:0048747 52 0.429
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.429
Fly
determination of bilateral symmetry GO:0009855 204 0.423
Zebrafish
extracellular structure organization GO:0043062 27 0.422
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 2 0.420
Fly
central nervous system development GO:0007417 387 0.419
regulation of stem cell proliferation GO:0072091 2 0.414
actin cytoskeleton organization GO:0030036 63 0.412
Fly
neuron projection development GO:0031175 180 0.411
regulation of locomotion GO:0040012 55 0.410
cell part morphogenesis GO:0032990 246 0.408
cell projection organization GO:0030030 284 0.404
epidermal cell differentiation GO:0009913 36 0.400
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.398
lymph vessel morphogenesis GO:0036303 25 0.396
Zebrafish
mesoderm formation GO:0001707 43 0.395
Zebrafish
auditory receptor cell fate commitment GO:0009912 4 0.394
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.393
striated muscle tissue development GO:0014706 110 0.392
Fly
endocrine system development GO:0035270 65 0.388
cellular response to stress GO:0033554 62 0.384
specification of organ identity GO:0010092 2 0.382
skeletal system development GO:0001501 181 0.381
Zebrafish
larval development GO:0002164 2 0.380
Worm Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.378
Rat Fly
regulation of rna biosynthetic process GO:2001141 213 0.377
Rat Fly
organ formation GO:0048645 17 0.368
Fly
body morphogenesis GO:0010171 16 0.362
Zebrafish Worm
regulation of cell development GO:0060284 100 0.362
cell cycle GO:0007049 93 0.362
Worm Fly
pancreas development GO:0031016 84 0.361
Zebrafish
segmentation GO:0035282 97 0.359
Zebrafish Fly
appendage morphogenesis GO:0035107 56 0.356
Fly
stem cell development GO:0048864 82 0.353
developmental process involved in reproduction GO:0003006 27 0.346
Worm Fly
regulation of mechanoreceptor differentiation GO:0045631 1 0.345
optic placode formation involved in camera type eye formation GO:0046619 3 0.343
auditory receptor cell differentiation GO:0042491 15 0.342
negative regulation of neuron projection regeneration GO:0070571 4 0.341
striated muscle cell differentiation GO:0051146 129 0.340
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.339
heart morphogenesis GO:0003007 156 0.337
glial cell fate determination GO:0007403 1 0.337
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.335
exocrine system development GO:0035272 28 0.334
Zebrafish
cell death GO:0008219 121 0.333
hematopoietic progenitor cell differentiation GO:0002244 23 0.332
single organism metabolic process GO:0044710 217 0.326
regulation of cell shape GO:0008360 1 0.326
mesenchymal cell differentiation GO:0048762 87 0.326
positive regulation of map kinase activity GO:0043406 3 0.324
aging GO:0007568 2 0.324
Worm Fly
apoptotic process involved in development GO:1902742 2 0.322
head morphogenesis GO:0060323 8 0.322
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.314
Rat Fly
biosynthetic process GO:0009058 294 0.314
Rat Fly
gland development GO:0048732 143 0.313
cell adhesion GO:0007155 40 0.313
Fly
cellular component biogenesis GO:0044085 178 0.312
Fly
protein localization to nucleus GO:0034504 3 0.310
cell projection assembly GO:0030031 64 0.308
Fly
innate immune response GO:0045087 13 0.308
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.307
Fly
negative regulation of angiogenesis GO:0016525 7 0.305
epidermis development GO:0008544 48 0.305
muscle structure development GO:0061061 196 0.302
Worm Fly
morphogenesis of an epithelial sheet GO:0002011 49 0.301
apoptotic process GO:0006915 116 0.298
muscle tissue development GO:0060537 110 0.298
Fly
commissural neuron axon guidance GO:0071679 3 0.297
cell growth GO:0016049 57 0.291
nuclear transport GO:0051169 4 0.285
formation of anatomical boundary GO:0048859 14 0.284
retina development in camera type eye GO:0060041 146 0.284
proximal distal pattern formation GO:0009954 1 0.281
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.280
immune system process GO:0002376 241 0.280
Fly
positive regulation of developmental process GO:0051094 50 0.280
Zebrafish
outflow tract morphogenesis GO:0003151 1 0.278
regulation of molecular function GO:0065009 70 0.277
fin morphogenesis GO:0033334 53 0.277
cartilage development GO:0051216 96 0.276
Zebrafish
specification of symmetry GO:0009799 204 0.273
Zebrafish
negative regulation of stem cell differentiation GO:2000737 2 0.273
regulation of axonogenesis GO:0050770 32 0.272
transmission of nerve impulse GO:0019226 19 0.271
positive regulation of mesodermal cell fate specification GO:0048337 1 0.270
Zebrafish
endodermal cell fate determination GO:0007493 2 0.268
regeneration GO:0031099 91 0.268
Zebrafish Rat
negative regulation of neurogenesis GO:0050768 20 0.268
odontogenesis of dentin containing tooth GO:0042475 1 0.266
auditory receptor cell development GO:0060117 8 0.265
multicellular organismal signaling GO:0035637 22 0.264
patterning of lymph vessels GO:0060854 1 0.264
macromolecule modification GO:0043412 111 0.263
Fly
inner ear receptor cell differentiation GO:0060113 29 0.262
nephron morphogenesis GO:0072028 2 0.262
positive regulation of cell cycle GO:0045787 3 0.260
Fly
small molecule metabolic process GO:0044281 77 0.259
nephron tubule development GO:0072080 4 0.259
protein metabolic process GO:0019538 183 0.259
Fly
regulation of organ growth GO:0046620 3 0.258
positive regulation of gene expression GO:0010628 71 0.258
Fly
positive regulation of myeloid cell differentiation GO:0045639 2 0.255
multi organism reproductive process GO:0044703 36 0.253
Worm Fly
regulation of glial cell proliferation GO:0060251 4 0.253
posterior lateral line development GO:0048916 38 0.252
regulation of cell communication GO:0010646 232 0.252
Fly
blood vessel endothelial cell differentiation GO:0060837 2 0.250
regulation of phospholipase activity GO:0010517 2 0.247
phosphate containing compound metabolic process GO:0006796 108 0.243
Fly
liver development GO:0001889 96 0.242
establishment of protein localization to organelle GO:0072594 4 0.241
regulation of canonical wnt signaling pathway GO:0060828 34 0.238
bmp signaling pathway GO:0030509 52 0.237
positive regulation of rna biosynthetic process GO:1902680 57 0.237
Fly
retinal ganglion cell axon guidance GO:0031290 35 0.237
skeletal system morphogenesis GO:0048705 102 0.236
Zebrafish
cellular protein modification process GO:0006464 100 0.235
Fly
cellular response to organic substance GO:0071310 105 0.234
positive regulation of jun kinase activity GO:0043507 2 0.230
nuclear import GO:0051170 3 0.230
heart looping GO:0001947 94 0.230
regulation of signaling GO:0023051 235 0.227
Fly
regulation of endothelial cell differentiation GO:0045601 3 0.227
regulation of cell migration GO:0030334 40 0.226
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 1 0.226
posterior lateral line neuromast deposition GO:0048922 5 0.226
protein import GO:0017038 3 0.225
positive regulation of cellular biosynthetic process GO:0031328 68 0.225
Fly
neuron projection morphogenesis GO:0048812 161 0.224
positive regulation of multicellular organismal process GO:0051240 52 0.223
Zebrafish
cell cell signaling involved in cell fate commitment GO:0045168 12 0.223
Worm Fly
convergent extension involved in organogenesis GO:0060029 10 0.223
central nervous system myelination GO:0022010 2 0.223
somite development GO:0061053 96 0.222
Zebrafish
regulation of phosphorus metabolic process GO:0051174 43 0.220
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.219
renal system development GO:0072001 94 0.217
system process GO:0003008 185 0.214
dorsal ventral pattern formation GO:0009953 125 0.214
Fly
astrocyte differentiation GO:0048708 1 0.214
regulation of nucleocytoplasmic transport GO:0046822 2 0.213
positive regulation of embryonic development GO:0040019 3 0.212
Zebrafish
positive regulation of jnk cascade GO:0046330 3 0.210
cellular response to nutrient levels GO:0031669 2 0.210
cell fate specification GO:0001708 68 0.210
Zebrafish Worm Fly
macromolecule biosynthetic process GO:0009059 227 0.209
Rat Fly
regulation of apoptotic process GO:0042981 98 0.209
neuron fate commitment GO:0048663 26 0.208
Mouse
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.207
female gonad development GO:0008585 4 0.206
nucleocytoplasmic transport GO:0006913 4 0.206
regulation of response to stimulus GO:0048583 269 0.205
Fly
single organism localization GO:1902578 225 0.204
mesenchyme development GO:0060485 127 0.202
cardiac atrium morphogenesis GO:0003209 2 0.200
mechanoreceptor differentiation GO:0042490 37 0.199
cell projection morphogenesis GO:0048858 244 0.198
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.198
regulation of cell cycle GO:0051726 52 0.198
Worm Fly
lateral line development GO:0048882 66 0.197
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.196
rhombomere morphogenesis GO:0021593 17 0.195
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.193
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.193
muscle cell development GO:0055001 115 0.192
appendage development GO:0048736 80 0.190
Fly
gamete generation GO:0007276 33 0.189
Fly
stem cell differentiation GO:0048863 117 0.188
pigment cell differentiation GO:0050931 38 0.188
muscle organ development GO:0007517 101 0.186
Worm Fly
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.184
positive regulation of stress activated mapk cascade GO:0032874 3 0.184
regulation of bmp signaling pathway GO:0030510 39 0.179
maintenance of blood brain barrier GO:0035633 1 0.179
ensheathment of neurons GO:0007272 18 0.178
death GO:0016265 121 0.177
regulation of myelination GO:0031641 1 0.177
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.176
reproductive process GO:0022414 40 0.176
Worm Fly
tissue remodeling GO:0048771 4 0.175
regulation of signal transduction GO:0009966 225 0.175
Fly
regulation of cellular component movement GO:0051270 55 0.174
regulation of reproductive process GO:2000241 4 0.174
diencephalon development GO:0021536 58 0.173
Zebrafish
regulation of jun kinase activity GO:0043506 3 0.173
regulation of cell growth GO:0001558 29 0.172
positive regulation of cell differentiation GO:0045597 30 0.171
Zebrafish
pharyngeal muscle development GO:0043282 4 0.170
Worm
skeletal muscle organ development GO:0060538 78 0.168
Fly
positive regulation of cell fate specification GO:0042660 1 0.168
Zebrafish
peripheral nervous system neuron differentiation GO:0048934 28 0.168
ear development GO:0043583 127 0.166
regulation of cell death GO:0010941 103 0.166
t cell differentiation GO:0030217 6 0.166
response to chemical GO:0042221 320 0.166
Fly
cellular response to extracellular stimulus GO:0031668 2 0.166
negative regulation of nervous system development GO:0051961 22 0.166
regulation of binding GO:0051098 3 0.166
leukocyte differentiation GO:0002521 25 0.165
gland morphogenesis GO:0022612 13 0.163
ear morphogenesis GO:0042471 64 0.163
regulation of retina development in camera type eye GO:1902866 2 0.162
negative regulation of cell motility GO:2000146 17 0.160
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.160
regulation of axon extension GO:0030516 24 0.160
extrinsic apoptotic signaling pathway GO:0097191 3 0.160
regulation of wnt signaling pathway GO:0030111 53 0.159
organ regeneration GO:0031100 1 0.158
embryonic camera type eye formation GO:0060900 10 0.158
cellular response to chemical stimulus GO:0070887 157 0.156
cell cycle process GO:0022402 53 0.155
Worm Fly
otolith morphogenesis GO:0032474 8 0.153
mesodermal cell differentiation GO:0048333 21 0.152
Zebrafish
rhombomere boundary formation GO:0021654 10 0.152
epithelial to mesenchymal transition GO:0001837 21 0.152
neural crest cell migration GO:0001755 42 0.151
ossification GO:0001503 23 0.151
epidermal cell fate specification GO:0009957 4 0.149
inner ear receptor cell fate commitment GO:0060120 4 0.149
otolith development GO:0048840 32 0.149
positive regulation of transcription dna templated GO:0045893 57 0.148
Fly
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.147
regulation of immune system process GO:0002682 34 0.147
venous blood vessel morphogenesis GO:0048845 3 0.146
central nervous system neuron differentiation GO:0021953 74 0.145
Zebrafish
homeostatic process GO:0042592 142 0.145
Fly
regulation of neuron differentiation GO:0045664 56 0.145
Mouse Fly
cellular response to external stimulus GO:0071496 2 0.144
post anal tail morphogenesis GO:0036342 19 0.144
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.143
multicellular organism growth GO:0035264 4 0.142
regulation of epithelial to mesenchymal transition GO:0010717 3 0.141
regulation of neural retina development GO:0061074 2 0.141
liver morphogenesis GO:0072576 8 0.140
tor signaling GO:0031929 7 0.139
regulation of cellular response to growth factor stimulus GO:0090287 35 0.138
intracellular signal transduction GO:0035556 85 0.137
Fly
establishment of localization in cell GO:0051649 77 0.137
heart formation GO:0060914 13 0.137
positive regulation of cell proliferation GO:0008284 15 0.136
Mouse Fly
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.136
negative regulation of cell differentiation GO:0045596 46 0.136
exocrine pancreas development GO:0031017 28 0.136
Zebrafish
embryonic digestive tract development GO:0048566 4 0.135
positive regulation of gastrulation GO:2000543 2 0.135
Zebrafish
cell recognition GO:0008037 19 0.135
nucleobase containing compound metabolic process GO:0006139 274 0.135
Rat Fly
osteoclast differentiation GO:0030316 1 0.133
aorta morphogenesis GO:0035909 3 0.133
respiratory system development GO:0060541 5 0.132
Fly
developmental pigmentation GO:0048066 48 0.132
regulation of organ morphogenesis GO:2000027 35 0.131
Zebrafish Fly
organelle localization GO:0051640 49 0.131
response to external stimulus GO:0009605 264 0.131
Fly
cilium assembly GO:0042384 58 0.130
protein targeting to nucleus GO:0044744 3 0.130
regionalization GO:0003002 274 0.129
Zebrafish Fly
regulation of multicellular organism growth GO:0040014 4 0.129
cardiocyte differentiation GO:0035051 44 0.129
Fly
immune response GO:0006955 28 0.129
spinal cord radial glial cell differentiation GO:0021531 2 0.129
Zebrafish
posterior lateral line neuromast development GO:0048919 20 0.128
optic placode formation GO:0001743 4 0.128
neuron projection extension GO:1990138 45 0.128
embryonic hemopoiesis GO:0035162 53 0.127
Fly
hormone metabolic process GO:0042445 19 0.127
single organism membrane organization GO:0044802 20 0.127
cellular response to growth factor stimulus GO:0071363 39 0.126
wound healing GO:0042060 90 0.124
Zebrafish Rat
cell substrate adhesion GO:0031589 4 0.124
positive regulation of cellular process GO:0048522 201 0.124
Zebrafish Mouse Fly
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.124
response to hormone GO:0009725 48 0.123
mesodermal cell migration GO:0008078 12 0.123
regulation of intracellular signal transduction GO:1902531 57 0.123
organelle fission GO:0048285 23 0.122
Worm
macromolecular complex subunit organization GO:0043933 74 0.122
Fly
otic vesicle morphogenesis GO:0071600 34 0.121
lymphangiogenesis GO:0001946 25 0.120
Zebrafish
mesodermal cell fate specification GO:0007501 12 0.120
Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.120
Fly
negative regulation of signal transduction GO:0009968 94 0.120
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.119
regulation of cytoplasmic transport GO:1903649 4 0.119
extracellular matrix organization GO:0030198 27 0.118
cellular component assembly involved in morphogenesis GO:0010927 107 0.118
Fly
positive regulation of molecular function GO:0044093 33 0.118
hindbrain development GO:0030902 91 0.117
negative regulation of myeloid cell differentiation GO:0045638 1 0.117
negative regulation of response to stimulus GO:0048585 104 0.116
developmental programmed cell death GO:0010623 4 0.115

notch3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.311
bone development disease DOID:0080006 0 0.307
bone disease DOID:0080001 0 0.307
musculoskeletal system disease DOID:17 0 0.307
connective tissue disease DOID:65 0 0.307