Danio rerio

0 known processes

si:dkey-27i16.2

si:dkey-27i16.2

(Aliases: sb:cb124,cb124)

si:dkey-27i16.2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to organic substance GO:0071310 105 0.310
regulation of cell communication GO:0010646 232 0.304
system process GO:0003008 185 0.255
cellular macromolecule metabolic process GO:0044260 391 0.253
cell surface receptor signaling pathway GO:0007166 325 0.251
regulation of biological quality GO:0065008 263 0.233
striated muscle cell differentiation GO:0051146 129 0.187
response to chemical GO:0042221 320 0.170
striated muscle cell development GO:0055002 108 0.168
regulation of cell activation GO:0050865 1 0.158
positive regulation of muscle cell differentiation GO:0051149 1 0.145
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.143
negative regulation of protein phosphorylation GO:0001933 4 0.129
negative regulation of biological process GO:0048519 304 0.127
localization of cell GO:0051674 244 0.125
homeostatic process GO:0042592 142 0.122
regulation of cellular amino acid metabolic process GO:0006521 0 0.121
cellular component movement GO:0006928 335 0.121
carboxylic acid metabolic process GO:0019752 22 0.117
signal transduction GO:0007165 455 0.113
muscle structure development GO:0061061 196 0.111
myoblast fusion GO:0007520 10 0.110
muscle cell differentiation GO:0042692 139 0.108
regulation of nitrogen compound metabolic process GO:0051171 251 0.108
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.107
glucose homeostasis GO:0042593 1 0.102
multicellular organismal macromolecule metabolic process GO:0044259 2 0.101
cell morphogenesis GO:0000902 289 0.100
regulation of cell differentiation GO:0045595 142 0.095
leukocyte proliferation GO:0070661 1 0.094
cellular ketone metabolic process GO:0042180 11 0.093
cellular component assembly involved in morphogenesis GO:0010927 107 0.089
single organism metabolic process GO:0044710 217 0.088
negative regulation of cellular process GO:0048523 283 0.085
cellular nitrogen compound metabolic process GO:0034641 290 0.082
reactive oxygen species metabolic process GO:0072593 6 0.081
cellular amine metabolic process GO:0044106 2 0.081
blood vessel morphogenesis GO:0048514 216 0.081
larval development GO:0002164 2 0.080
regulation of anatomical structure morphogenesis GO:0022603 130 0.080
cellular component morphogenesis GO:0032989 336 0.080
protein metabolic process GO:0019538 183 0.079
regulation of response to stimulus GO:0048583 269 0.078
ion transport GO:0006811 114 0.078
organic acid metabolic process GO:0006082 31 0.076
syncytium formation GO:0006949 12 0.075
positive regulation of inflammatory response GO:0050729 1 0.072
negative regulation of cell communication GO:0010648 96 0.069
regulation of signal transduction GO:0009966 225 0.068
response to stress GO:0006950 263 0.068
regulation of developmental process GO:0050793 247 0.067
cell cycle g1 s phase transition GO:0044843 1 0.067
cellular component assembly GO:0022607 170 0.067
regulation of cellular amine metabolic process GO:0033238 0 0.067
amine metabolic process GO:0009308 2 0.066
regulation of immune response GO:0050776 14 0.065
regulation of macromolecule metabolic process GO:0060255 317 0.064
regulation of multicellular organismal process GO:0051239 277 0.064
positive regulation of cellular process GO:0048522 201 0.061
sensory organ development GO:0007423 393 0.060
inflammatory response GO:0006954 8 0.059
muscle cell development GO:0055001 115 0.059
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.058
superoxide metabolic process GO:0006801 2 0.057
cellular response to chemical stimulus GO:0070887 157 0.055
regulation of primary metabolic process GO:0080090 311 0.055
response to organic substance GO:0010033 153 0.054
establishment of localization GO:0051234 244 0.054
stem cell proliferation GO:0072089 4 0.053
cellular amino acid metabolic process GO:0006520 7 0.053
cellular response to endogenous stimulus GO:0071495 68 0.051
cellular protein modification process GO:0006464 100 0.051
regulation of signaling GO:0023051 235 0.050
positive regulation of cytokine production GO:0001819 2 0.048
positive regulation of biological process GO:0048518 253 0.048
single organism organelle organization GO:1902589 199 0.048
positive regulation of cytoskeleton organization GO:0051495 3 0.048
cellular protein catabolic process GO:0044257 4 0.048
cortical cytoskeleton organization GO:0030865 1 0.047
organelle fusion GO:0048284 3 0.046
small molecule metabolic process GO:0044281 77 0.046
response to wounding GO:0009611 116 0.045
positive regulation of cell activation GO:0050867 1 0.045
single organism transport GO:0044765 206 0.045
positive regulation of response to stimulus GO:0048584 80 0.045
actin cytoskeleton organization GO:0030036 63 0.044
maintenance of location GO:0051235 4 0.044
cytoskeleton organization GO:0007010 96 0.044
actomyosin structure organization GO:0031032 53 0.044
regulation of metabolic process GO:0019222 359 0.043
g1 s transition of mitotic cell cycle GO:0000082 1 0.043
digestive tract development GO:0048565 265 0.043
protein modification process GO:0036211 100 0.043
response to external stimulus GO:0009605 264 0.042
actin filament based process GO:0030029 64 0.042
negative regulation of kinase activity GO:0033673 4 0.041
regulation of receptor activity GO:0010469 2 0.041
generation of neurons GO:0048699 385 0.040
response to endogenous stimulus GO:0009719 83 0.040
carbohydrate homeostasis GO:0033500 1 0.039
single organism nuclear import GO:1902593 3 0.039
tissue remodeling GO:0048771 4 0.039
t cell differentiation in thymus GO:0033077 6 0.038
regulation of myotube differentiation GO:0010830 2 0.037
negative regulation of secretion by cell GO:1903531 2 0.037
positive regulation of cellular component biogenesis GO:0044089 3 0.037
negative regulation of protein kinase activity GO:0006469 4 0.037
modification dependent macromolecule catabolic process GO:0043632 3 0.036
organelle organization GO:0006996 227 0.036
positive regulation of protein complex assembly GO:0031334 2 0.036
positive regulation of transport GO:0051050 2 0.036
epithelial cell morphogenesis GO:0003382 2 0.035
transport GO:0006810 220 0.035
phagosome maturation GO:0090382 1 0.035
death GO:0016265 121 0.035
blood vessel development GO:0001568 246 0.035
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.034
establishment of protein localization to organelle GO:0072594 4 0.034
organelle assembly GO:0070925 110 0.034
angiogenesis GO:0001525 158 0.034
positive regulation of striated muscle cell differentiation GO:0051155 1 0.034
oxoacid metabolic process GO:0043436 31 0.034
enzyme linked receptor protein signaling pathway GO:0007167 106 0.033
response to biotic stimulus GO:0009607 97 0.033
regionalization GO:0003002 274 0.032
regulation of transmembrane transporter activity GO:0022898 2 0.032
regulation of protein transport GO:0051223 3 0.032
regulation of protein complex assembly GO:0043254 3 0.032
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.031
syncytium formation by plasma membrane fusion GO:0000768 12 0.030
regulation of cytoplasmic transport GO:1903649 4 0.030
regulation of inflammatory response GO:0050727 2 0.030
negative regulation of response to stimulus GO:0048585 104 0.030
cell morphogenesis involved in differentiation GO:0000904 195 0.030
regulation of cellular ketone metabolic process GO:0010565 7 0.029
ribonucleoside monophosphate catabolic process GO:0009158 4 0.029
cell motility GO:0048870 244 0.029
neuron differentiation GO:0030182 353 0.029
muscle tissue development GO:0060537 110 0.029
defense response GO:0006952 47 0.029
regulation of embryonic development GO:0045995 47 0.029
phosphorus metabolic process GO:0006793 109 0.029
regulation of phosphate metabolic process GO:0019220 43 0.028
central nervous system development GO:0007417 387 0.028
single organism localization GO:1902578 225 0.028
cytoskeleton dependent cytokinesis GO:0061640 3 0.028
skeletal system development GO:0001501 181 0.028
negative regulation of chemotaxis GO:0050922 4 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.027
cell death GO:0008219 121 0.027
negative regulation of secretion GO:0051048 2 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
immune system process GO:0002376 241 0.027
leukocyte activation GO:0045321 12 0.027
stem cell maintenance GO:0019827 4 0.027
regulation of localization GO:0032879 104 0.027
compound eye development GO:0048749 2 0.027
positive regulation of cell cycle GO:0045787 3 0.026
cell cycle arrest GO:0007050 1 0.026
negative regulation of signal transduction GO:0009968 94 0.026
cortical actin cytoskeleton organization GO:0030866 1 0.026
negative regulation of cytokine production GO:0001818 1 0.026
immune response GO:0006955 28 0.026
mononuclear cell proliferation GO:0032943 1 0.025
response to carbohydrate GO:0009743 3 0.025
nuclear transport GO:0051169 4 0.025
negative regulation of intracellular transport GO:0032387 3 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.025
convergent extension GO:0060026 118 0.025
blood circulation GO:0008015 87 0.024
regulation of cell death GO:0010941 103 0.024
multi organism process GO:0051704 134 0.024
adult behavior GO:0030534 2 0.024
cell activation GO:0001775 16 0.024
regulation of metal ion transport GO:0010959 4 0.024
phosphate containing compound metabolic process GO:0006796 108 0.024
vasculature development GO:0001944 278 0.024
defense response to fungus GO:0050832 2 0.024
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.024
purine nucleoside monophosphate catabolic process GO:0009128 4 0.024
regulation of ion transmembrane transporter activity GO:0032412 2 0.024
regulation of calcium ion transport GO:0051924 2 0.024
actin filament polymerization GO:0030041 2 0.024
cell projection morphogenesis GO:0048858 244 0.023
cellular component biogenesis GO:0044085 178 0.023
lymphocyte proliferation GO:0046651 1 0.023
regulation of muscle contraction GO:0006937 3 0.023
head development GO:0060322 303 0.023
negative regulation of immune response GO:0050777 2 0.022
cellular protein metabolic process GO:0044267 129 0.022
alcohol biosynthetic process GO:0046165 2 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
macromolecule modification GO:0043412 111 0.022
protein acetylation GO:0006473 2 0.022
lymphocyte activation GO:0046649 10 0.022
circulatory system process GO:0003013 87 0.021
regulation of cellular component organization GO:0051128 86 0.021
positive regulation of map kinase activity GO:0043406 3 0.021
proteasomal protein catabolic process GO:0010498 2 0.021
regulation of multicellular organismal development GO:2000026 223 0.021
protein stabilization GO:0050821 2 0.021
cellular carbohydrate metabolic process GO:0044262 4 0.021
positive regulation of leukocyte differentiation GO:1902107 1 0.021
reactive oxygen species biosynthetic process GO:1903409 1 0.021
epiboly GO:0090504 41 0.021
cytokinesis GO:0000910 3 0.021
protein import into nucleus GO:0006606 3 0.021
establishment of localization in cell GO:0051649 77 0.021
membrane fusion GO:0061025 2 0.021
nuclear import GO:0051170 3 0.020
extracellular matrix organization GO:0030198 27 0.020
innate immune response GO:0045087 13 0.020
regulation of cell proliferation GO:0042127 37 0.020
ubiquitin dependent protein catabolic process GO:0006511 3 0.020
production of molecular mediator of immune response GO:0002440 2 0.020
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
mitotic dna integrity checkpoint GO:0044774 4 0.020
myotube differentiation GO:0014902 45 0.020
organic substance transport GO:0071702 58 0.020
protein polymerization GO:0051258 4 0.020
response to hexose GO:0009746 3 0.020
axon development GO:0061564 166 0.020
organic substance biosynthetic process GO:1901576 289 0.020
digestive system development GO:0055123 289 0.020
atp catabolic process GO:0006200 4 0.019
mitotic cell cycle process GO:1903047 48 0.019
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.019
regulation of reactive oxygen species metabolic process GO:2000377 2 0.019
protein complex subunit organization GO:0071822 46 0.019
sarcomere organization GO:0045214 26 0.019
regulation of carbohydrate metabolic process GO:0006109 4 0.019
intracellular signal transduction GO:0035556 85 0.019
organonitrogen compound metabolic process GO:1901564 74 0.019
synaptic vesicle endocytosis GO:0048488 1 0.019
taxis GO:0042330 109 0.019
cognition GO:0050890 1 0.019
regulation of protein catabolic process GO:0042176 1 0.019
tissue regeneration GO:0042246 74 0.018
cellular biosynthetic process GO:0044249 286 0.018
mitotic dna damage checkpoint GO:0044773 4 0.018
intra s dna damage checkpoint GO:0031573 1 0.018
cellular localization GO:0051641 97 0.018
regulation of synapse assembly GO:0051963 3 0.018
single organism membrane fusion GO:0044801 2 0.018
regulation of production of molecular mediator of immune response GO:0002700 1 0.018
regulation of epithelial cell proliferation GO:0050678 3 0.018
ameboidal type cell migration GO:0001667 143 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
lateral line development GO:0048882 66 0.018
multicellular organismal metabolic process GO:0044236 2 0.017
regulation of meiotic cell cycle GO:0051445 1 0.017
cellular response to molecule of bacterial origin GO:0071219 3 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.017
regulation of reproductive process GO:2000241 4 0.017
heterocycle metabolic process GO:0046483 290 0.017
endosomal transport GO:0016197 2 0.017
nitric oxide metabolic process GO:0046209 2 0.017
somatic stem cell maintenance GO:0035019 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
peptidyl lysine acetylation GO:0018394 2 0.017
protein targeting to membrane GO:0006612 1 0.017
positive regulation of cell differentiation GO:0045597 30 0.017
cell fate commitment GO:0045165 99 0.016
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.016
regulation of cytokine production GO:0001817 3 0.016
positive regulation of multicellular organismal process GO:0051240 52 0.016
protein dephosphorylation GO:0006470 3 0.016
biosynthetic process GO:0009058 294 0.016
dorsal ventral pattern formation GO:0009953 125 0.016
cell cycle g2 m phase transition GO:0044839 4 0.016
long chain fatty acid biosynthetic process GO:0042759 1 0.016
brain development GO:0007420 293 0.016
regulation of synapse organization GO:0050807 3 0.016
peptidyl tyrosine modification GO:0018212 5 0.016
negative regulation of chromosome organization GO:2001251 1 0.016
response to zinc ion GO:0010043 6 0.016
t cell activation GO:0042110 6 0.016
synaptic vesicle localization GO:0097479 1 0.016
modification dependent protein catabolic process GO:0019941 3 0.016
myofibril assembly GO:0030239 48 0.016
cellular extravasation GO:0045123 1 0.015
cell proliferation GO:0008283 80 0.015
cell projection organization GO:0030030 284 0.015
digestive tract morphogenesis GO:0048546 231 0.015
cellular macromolecule biosynthetic process GO:0034645 224 0.015
growth GO:0040007 174 0.015
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.015
negative regulation of nuclear division GO:0051784 3 0.015
long chain fatty acid metabolic process GO:0001676 1 0.015
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.015
nucleocytoplasmic transport GO:0006913 4 0.015
positive regulation of metabolic process GO:0009893 108 0.015
tyrosine phosphorylation of stat protein GO:0007260 1 0.015
protein targeting to nucleus GO:0044744 3 0.015
stem cell differentiation GO:0048863 117 0.015
regulation of cytokine mediated signaling pathway GO:0001959 3 0.015
regulation of multicellular organism growth GO:0040014 4 0.015
regulation of protein modification process GO:0031399 29 0.015
regulation of purine nucleotide catabolic process GO:0033121 2 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
regulation of immune system process GO:0002682 34 0.014
long chain fatty acid transport GO:0015909 1 0.014
chemotaxis GO:0006935 104 0.014
regulation of protein phosphorylation GO:0001932 18 0.014
lipid storage GO:0019915 1 0.014
epithelium migration GO:0090132 25 0.014
regulation of dna replication GO:0006275 3 0.014
regulation of transporter activity GO:0032409 2 0.014
negative regulation of multicellular organismal process GO:0051241 69 0.014
spinal cord radial glial cell differentiation GO:0021531 2 0.014
protein secretion GO:0009306 1 0.014
regulation of erk1 and erk2 cascade GO:0070372 4 0.014
response to abiotic stimulus GO:0009628 122 0.014
pole plasm assembly GO:0007315 4 0.014
negative regulation of leukocyte differentiation GO:1902106 1 0.014
chemical homeostasis GO:0048878 49 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
axonogenesis GO:0007409 152 0.014
striated muscle tissue development GO:0014706 110 0.014
negative regulation of signaling GO:0023057 96 0.014
regulation of cellular component movement GO:0051270 55 0.014
neurological system process GO:0050877 62 0.014
regulation of cell shape GO:0008360 1 0.014
intracellular transport GO:0046907 32 0.014
wound healing GO:0042060 90 0.013
positive regulation of catabolic process GO:0009896 4 0.013
positive regulation of immune effector process GO:0002699 3 0.013
regulation of jun kinase activity GO:0043506 3 0.013
regulation of tissue remodeling GO:0034103 2 0.013
organic cyclic compound biosynthetic process GO:1901362 223 0.013
phagocytosis GO:0006909 3 0.013
cell chemotaxis GO:0060326 17 0.013
positive regulation of cell communication GO:0010647 56 0.013
actin filament based movement GO:0030048 1 0.013
neuromast development GO:0048884 46 0.013
negative regulation of defense response GO:0031348 2 0.013
cellular response to stress GO:0033554 62 0.013
single organism biosynthetic process GO:0044711 71 0.013
negative regulation of epithelial cell proliferation GO:0050680 1 0.013
response to monosaccharide GO:0034284 3 0.013
morphogenesis of an epithelium GO:0002009 333 0.013
heart contraction GO:0060047 71 0.013
muscle organ development GO:0007517 101 0.013
liver development GO:0001889 96 0.013
macromolecular complex subunit organization GO:0043933 74 0.013
protein localization to nucleus GO:0034504 3 0.012
gtp catabolic process GO:0006184 2 0.012
response to drug GO:0042493 3 0.012
negative regulation of cell differentiation GO:0045596 46 0.012
positive regulation of secretion GO:0051047 1 0.012
chemosensory behavior GO:0007635 1 0.012
cellular component disassembly GO:0022411 1 0.012
regulation of transferase activity GO:0051338 16 0.012
smooth muscle contraction GO:0006939 2 0.012
regulation of nucleoside metabolic process GO:0009118 2 0.012
positive regulation of developmental process GO:0051094 50 0.012
complement activation GO:0006956 3 0.012
astrocyte differentiation GO:0048708 1 0.012
spermatid development GO:0007286 2 0.012
immune system development GO:0002520 191 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.012
protein complex localization GO:0031503 1 0.012
regulation of locomotion GO:0040012 55 0.012
organic acid biosynthetic process GO:0016053 12 0.012
hepaticobiliary system development GO:0061008 98 0.012
regulation of cell cycle GO:0051726 52 0.012
rna localization GO:0006403 4 0.012
response to growth factor GO:0070848 39 0.012
epidermal cell fate specification GO:0009957 4 0.012
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.012
fatty acid biosynthetic process GO:0006633 4 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of stem cell proliferation GO:0072091 2 0.012
meiotic cell cycle process GO:1903046 3 0.011
embryonic digestive tract morphogenesis GO:0048557 3 0.011
regulation of kinase activity GO:0043549 15 0.011
protein import GO:0017038 3 0.011
positive regulation of stress activated mapk cascade GO:0032874 3 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
regulation of organelle organization GO:0033043 29 0.011
ectodermal placode morphogenesis GO:0071697 32 0.011
positive regulation of stem cell proliferation GO:2000648 1 0.011
cell adhesion GO:0007155 40 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.011
regulation of homeostatic process GO:0032844 9 0.011
regulation of oligodendrocyte differentiation GO:0048713 1 0.011
protein phosphorylation GO:0006468 47 0.011
nucleobase containing compound biosynthetic process GO:0034654 205 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.011
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.011
mechanosensory lateral line system development GO:0048881 49 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
establishment of protein localization to plasma membrane GO:0090002 1 0.011
positive regulation of signaling GO:0023056 56 0.011
forebrain development GO:0030900 96 0.011
calcium ion dependent exocytosis GO:0017156 1 0.011
small molecule biosynthetic process GO:0044283 16 0.011
positive regulation of cell division GO:0051781 2 0.011
regulation of response to cytokine stimulus GO:0060759 3 0.011
regulation of response to external stimulus GO:0032101 31 0.011
receptor internalization GO:0031623 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
negative regulation of developmental process GO:0051093 65 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
regulation of autophagy GO:0010506 3 0.010
transmembrane transport GO:0055085 120 0.010
regulation of establishment of protein localization GO:0070201 4 0.010
peptide transport GO:0015833 1 0.010
negative regulation of cellular metabolic process GO:0031324 77 0.010
germ line stem cell maintenance GO:0030718 2 0.010
aromatic compound biosynthetic process GO:0019438 217 0.010
positive regulation of immune system process GO:0002684 17 0.010
b cell activation GO:0042113 2 0.010
calcium ion transport into cytosol GO:0060402 3 0.010
leukocyte chemotaxis GO:0030595 12 0.010
regulation of ph GO:0006885 3 0.010
heart process GO:0003015 71 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
regulation of programmed cell death GO:0043067 101 0.010
ion homeostasis GO:0050801 41 0.010
double strand break repair GO:0006302 3 0.010
neuron development GO:0048666 262 0.010

si:dkey-27i16.2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
immune system disease DOID:2914 0 0.037