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Danio rerio

2 genes annotated in zebrafish

spinal cord radial glial cell differentiation

The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "spinal cord radial glial cell differentiation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "spinal cord radial glial cell differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
sfrp1a	secreted frizzled-related protein 1a	0.607
tbx5a	T-box 5a	0.508
fzd7a	frizzled homolog 7a	0.436
fzd7b	frizzled homolog 7b	0.416	Zebrafish
cdh2	cadherin 2, neuronal	0.347
fzd8a	frizzled homolog 8a	0.347
spry2	sprouty homolog 2	0.343
fn1	fibronectin 1	0.297
ephb3a	eph receptor B3a	0.290
her6	hairy-related 6	0.252
foxc1a	forkhead box C1a	0.241
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.223
hsp47	heat shock protein 47	0.198
lmo4a	LIM domain only 4a	0.173
twist1a	twist1a	0.158
pea3	ETS-domain transcription factor pea3	0.155
foxa2	forkhead box A2	0.150
notch2	notch homolog 2	0.142	Zebrafish
jag1b	jagged 1b	0.140
eya1	eyes absent homolog 1	0.137
dkk1b	dickkopf 1b	0.135
dag1	dystroglycan 1	0.135
notch3	notch homolog 3	0.129	Zebrafish
six4b	sine oculis homeobox homolog 4b	0.127
gro1	groucho 1	0.116
tbx1	T-box 1	0.115
dlc	deltaC	0.109
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.103
klf4	Kruppel-like factor 4	0.102
dla	deltaA	0.090
ephb4a	eph receptor B4a	0.083
bmper	BMP binding endothelial regulator	0.082
yap1	Yes-associated protein 1	0.081
rarga	retinoic acid receptor gamma a	0.079
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.073
smarca4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.073
sox2	SRY-box containing gene 2	0.073
ephb4b	eph receptor B4b	0.073
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.072
nrarpa	notch-regulated ankyrin repeat protein a	0.070
bmp4	bone morphogenetic protein 4	0.070
tjp1	tight junction protein 1 (zona occludens 1)	0.069
lamc1	laminin, gamma 1	0.069
gro2	groucho 2	0.065
ptch1	patched 1	0.061
rx3	retinal homeobox gene 3	0.060
dld	deltaD	0.060
fli1a	friend leukemia integration 1a	0.059
crabp2b	cellular retinoic acid binding protein 2, b	0.055
lama5	laminin, alpha 5	0.052
igfbp3	insulin-like growth factor binding protein 3	0.052
gsc	goosecoid	0.052
dlx2a	distal-less homeobox gene 2a	0.049
id1	inhibitor of DNA binding 1	0.046
acvr1b	activin A receptor, type IB	0.046
tagln2	transgelin 2	0.044
ctsl1b	cathepsin L, 1 b	0.043
shhb	sonic hedgehog b	0.042
foxn4	forkhead box N4	0.040
gli2a	GLI-Kruppel family member GLI2a	0.040
lamb1a	laminin, beta 1a	0.038
col5a2l	collagen, type V, alpha 2-like	0.037
gyltl1b	glycosyltransferase-like 1b	0.037
wif1	wnt inhibitory factor 1	0.036
dlx3b	distal-less homeobox gene 3b	0.035
axin2	axin 2 (conductin, axil)	0.035
wnt11	wingless-type MMTV integration site family, member 11	0.035
hmgb3a	high-mobility group box 3a	0.032
rest	RE1-silencing transcription factor	0.030
gdf6b	growth differentiation factor 6b	0.029
si:ch73-60e21.1	si:ch73-60e21.1	0.029
snai2	snail homolog 2 (Drosophila)	0.029
scube2	signal peptide, CUB domain, EGF-like 2	0.029
her3	hairy-related 3	0.029
otx2	orthodenticle homolog 2	0.029
etv2	ets variant gene 2	0.028
tp63	tumor protein p63	0.027
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.027
nkx3.2	NK3 homeobox 2	0.027
inka1a	induced in neural crest by AP2, 1a	0.026
vangl2	vang-like 2 (van gogh, Drosophila)	0.025
krt8	keratin 8	0.025
nrarpb	notch-regulated ankyrin repeat protein b	0.025
wnt5b	wingless-type MMTV integration site family, member 5b	0.024
fgfrl1a	fibroblast growth factor receptor-like 1a	0.024
foxa3	forkhead box A3	0.024
six2a	sine oculis-related homeobox 2a	0.024
hesx1	homeo box (expressed in ES cells) 1	0.024
epha4b	eph receptor A4b	0.023
pmp22a	peripheral myelin protein 22a	0.023
ednra	endothelin receptor type A	0.023
fgfr4	fibroblast growth factor receptor 4	0.023
fzd8b	frizzled homolog 8b	0.023	Zebrafish
si:ch211-212m21.5	si:ch211-212m21.5	0.023
fkbp10	FK506 binding protein 10	0.023
mmp2	matrix metalloproteinase 2	0.022
sf3b1	splicing factor 3b, subunit 1	0.022
runx3	runt-related transcription factor 3	0.021
znf703	zinc finger protein 703	0.021
plcg1	phospholipase C, gamma 1	0.021
bmp2b	bone morphogenetic protein 2b	0.021
atp1b3a	ATPase, Na+/K+ transporting, beta 3a polypeptide	0.020
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.020
tmpoa	thymopoietin a	0.020
sh3gl1b	SH3-domain GRB2-like 1b	0.020
gli1	GLI-Kruppel family member 1	0.020
fzd9b	frizzled homolog 9b	0.019	Zebrafish
ihha	Indian hedgehog homolog a	0.019
yrk	Yes-related kinase	0.019
lhx5	LIM homeobox 5	0.019
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.019
creb1	cAMP responsive element binding protein 1	0.018
her9	hairy-related 9	0.018
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.018
foxa1	forkhead box A1	0.018
sulf1	sulfatase 1	0.018
akap12b	A kinase (PRKA) anchor protein (gravin) 12b	0.018
cxcr4b	chemokine (C-X-C motif), receptor 4b	0.018
pkd2	polycystic kidney disease 2	0.018
mych	myelocytomatosis oncogene homolog	0.017
mib	mind bomb	0.017
ptprk	protein tyrosine phosphatase, receptor type, K	0.017
fzd2	frizzled homolog 2	0.017	Zebrafish
twist2	twist2	0.017
ndr2	nodal-related 2	0.017
metrn	meteorin, glial cell differentiation regulator	0.017
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.017
st8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.016
rxrbb	retinoid x receptor, beta b	0.016
cnn2	calponin 2	0.016
jag2	jagged 2	0.016
cpn1	carboxypeptidase N, polypeptide 1	0.016
her1	hairy-related 1	0.016
igfbp1a	insulin-like growth factor binding protein 1a	0.016
ntla	no tail a	0.016
gata1a	GATA binding protein 1a	0.016
dhrs3a	dehydrogenase/reductase (SDR family) member 3a	0.016
znf503	zinc finger protein 503	0.016
lama4	laminin, alpha 4	0.015
sept9a	septin 9a	0.015
tagln	transgelin	0.015
trim33	tripartite motif-containing 33	0.015
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.015
wnt2bb	wingless-type MMTV integration site family, member 2Bb	0.014
si:dkey-27i16.2	si:dkey-27i16.2	0.014
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.014
sox3	SRY-box containing gene 3	0.014
rcn3	reticulocalbin 3, EF-hand calcium binding domain	0.014
cdx1b	caudal type homeobox 1 b	0.014
rfx2	regulatory factor X, 2 (influences HLA class II expression)	0.014
six1b	sine oculis homeobox homolog 1b	0.014
ryk	receptor-like tyrosine kinase	0.014
nkx2.1a	NK2 homeobox 1a	0.014
lhx1b	LIM homeobox 1b	0.013
nanos3	nanos homolog 3	0.013
ptgs1	prostaglandin-endoperoxide synthase 1	0.013
fgfrl1b	fibroblast growth factor receptor-like 1b	0.013
cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.013
hs6st2	heparan sulfate 6-O-sulfotransferase 2	0.013
wls	wntless homolog (Drosophila)	0.012
cbfb	core-binding factor, beta subunit	0.012
tgfbr2	transforming growth factor, beta receptor II	0.012
zfand5a	zinc finger, AN1-type domain 5a	0.012
ccnd1	cyclin D1	0.012
klf2a	Kruppel-like factor 2a	0.012
arl4ab	ADP-ribosylation factor-like 4ab	0.012
tcf7	transcription factor 7 (T-cell specific, HMG-box)	0.012
zic6	zic family member 6	0.012
bhlhe41	basic helix-loop-helix family, member e41	0.011
cyp26c1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.011
ppp1r14bb	protein phosphatase 1, regulatory (inhibitor) subunit 14Bb	0.011
ptbp1b	polypyrimidine tract binding protein 1b	0.011
dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.011
LOC100333872	alpha-N-acetylneuraminide alpha-2,8-sialyltransferase-like	0.011
sdc2	syndecan 2	0.011
her12	hairy-related 12	0.011
lft1	lefty1	0.011
col27a1a	collagen, type XXVII, alpha 1a	0.011
sema3h	semaphorin 3h	0.011
zgc:110105	zgc:110105	0.011
rx1	retinal homeobox gene 1	0.011
zgc:136773	zgc:136773	0.011
ndr1	nodal-related 1	0.011
pdcd4a	programmed cell death 4a	0.011
id3	inhibitor of DNA binding 3	0.011
igf1	insulin-like growth factor 1	0.010
tmem2	transmembrane protein 2	0.010
plagx	pleiomorphic adenoma gene X	0.010
kal1b	Kallmann syndrome 1b sequence	0.010
gbx1	gastrulation brain homeobox 1	0.010
sesn1	sestrin 1	0.010
efnb2a	ephrin B2a	0.010
tbx16	T-box gene 16	0.010
cdh1	cadherin 1, epithelial	0.010