Danio rerio

0 known processes

rufy3

RUN and FYVE domain containing 3

(Aliases: wu:fj64d11,zgc:110543,MGC158578,im:7148884)

rufy3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aging GO:0007568 2 0.067
larval development GO:0002164 2 0.057
cellular component movement GO:0006928 335 0.056
multicellular organism growth GO:0035264 4 0.054
eye development GO:0001654 277 0.051
central nervous system development GO:0007417 387 0.048
positive regulation of cellular component biogenesis GO:0044089 3 0.044
stem cell proliferation GO:0072089 4 0.044
regulation of multicellular organism growth GO:0040014 4 0.044
phagocytosis GO:0006909 3 0.041
brain development GO:0007420 293 0.040
cell part morphogenesis GO:0032990 246 0.038
Rat
embryonic organ morphogenesis GO:0048562 274 0.038
sensory organ development GO:0007423 393 0.038
exocytosis GO:0006887 1 0.037
neuron differentiation GO:0030182 353 0.036
Rat
generation of neurons GO:0048699 385 0.035
Rat
cellular macromolecule metabolic process GO:0044260 391 0.035
lipid storage GO:0019915 1 0.034
adult behavior GO:0030534 2 0.033
axonogenesis GO:0007409 152 0.033
Rat
neuron development GO:0048666 262 0.033
Rat
system process GO:0003008 185 0.032
regulation of protein complex assembly GO:0043254 3 0.032
signal transduction GO:0007165 455 0.031
maintenance of location GO:0051235 4 0.031
regulation of multicellular organismal process GO:0051239 277 0.030
Rat
cell morphogenesis GO:0000902 289 0.029
Rat
vasculature development GO:0001944 278 0.029
regulation of synapse organization GO:0050807 3 0.029
positive regulation of cell cycle GO:0045787 3 0.029
organelle organization GO:0006996 227 0.028
cell motility GO:0048870 244 0.028
regulation of synapse assembly GO:0051963 3 0.027
regulation of reproductive process GO:2000241 4 0.027
embryonic organ development GO:0048568 381 0.027
mitochondrion organization GO:0007005 4 0.027
positive regulation of protein complex assembly GO:0031334 2 0.027
negative regulation of biological process GO:0048519 304 0.027
Rat
sensory organ morphogenesis GO:0090596 200 0.026
positive regulation of transport GO:0051050 2 0.026
cell migration GO:0016477 237 0.026
neuron projection development GO:0031175 180 0.026
Rat
localization of cell GO:0051674 244 0.025
regulation of cell shape GO:0008360 1 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.025
protein polymerization GO:0051258 4 0.025
regulation of protein polymerization GO:0032271 2 0.025
developmental growth GO:0048589 166 0.024
regulation of biological quality GO:0065008 263 0.024
positive regulation of cytoskeleton organization GO:0051495 3 0.024
cognition GO:0050890 1 0.024
cellular component morphogenesis GO:0032989 336 0.024
Rat
blood vessel development GO:0001568 246 0.024
tissue remodeling GO:0048771 4 0.024
axon development GO:0061564 166 0.024
Rat
erk1 and erk2 cascade GO:0070371 4 0.024
cell morphogenesis involved in differentiation GO:0000904 195 0.024
Rat
morphogenesis of an epithelium GO:0002009 333 0.024
camera type eye development GO:0043010 222 0.024
cell projection organization GO:0030030 284 0.024
Rat
meiotic nuclear division GO:0007126 4 0.023
stem cell maintenance GO:0019827 4 0.023
rna localization GO:0006403 4 0.023
autophagy GO:0006914 4 0.023
neuroblast proliferation GO:0007405 2 0.023
synaptic vesicle transport GO:0048489 1 0.023
head development GO:0060322 303 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
neurotransmitter transport GO:0006836 2 0.022
cellular ketone metabolic process GO:0042180 11 0.022
nitrogen compound metabolic process GO:0006807 319 0.022
immune system process GO:0002376 241 0.022
amine metabolic process GO:0009308 2 0.022
cell surface receptor signaling pathway GO:0007166 325 0.022
regulation of mrna processing GO:0050684 3 0.022
synaptic growth at neuromuscular junction GO:0051124 2 0.022
synaptic vesicle localization GO:0097479 1 0.022
negative regulation of cellular process GO:0048523 283 0.022
Rat
regulation of ion transmembrane transporter activity GO:0032412 2 0.022
protein dephosphorylation GO:0006470 3 0.022
guanosine containing compound catabolic process GO:1901069 2 0.022
organic cyclic compound metabolic process GO:1901360 301 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
regulation of response to stimulus GO:0048583 269 0.021
actin polymerization or depolymerization GO:0008154 2 0.021
single organism membrane fusion GO:0044801 2 0.021
positive regulation of catabolic process GO:0009896 4 0.021
cellular response to nutrient levels GO:0031669 2 0.021
cellular response to starvation GO:0009267 1 0.021
membrane fusion GO:0061025 2 0.021
compound eye development GO:0048749 2 0.020
chemosensory behavior GO:0007635 1 0.020
cellular amine metabolic process GO:0044106 2 0.020
cell projection morphogenesis GO:0048858 244 0.020
Rat
tube morphogenesis GO:0035239 349 0.020
protein localization to plasma membrane GO:0072659 1 0.020
response to chemical GO:0042221 320 0.020
phagocytosis engulfment GO:0006911 1 0.020
locomotion GO:0040011 313 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
regulation of dendrite development GO:0050773 3 0.019
positive regulation of cellular catabolic process GO:0031331 3 0.019
cellular response to external stimulus GO:0071496 2 0.019
gtp catabolic process GO:0006184 2 0.019
single organism transport GO:0044765 206 0.019
pancreas development GO:0031016 84 0.019
single fertilization GO:0007338 3 0.019
establishment of localization GO:0051234 244 0.019
chordate embryonic development GO:0043009 271 0.019
membrane invagination GO:0010324 1 0.019
organic cyclic compound biosynthetic process GO:1901362 223 0.019
neuron projection morphogenesis GO:0048812 161 0.019
Rat
eye morphogenesis GO:0048592 144 0.019
oxoacid metabolic process GO:0043436 31 0.019
skeletal system development GO:0001501 181 0.019
positive regulation of protein polymerization GO:0032273 2 0.019
single organism metabolic process GO:0044710 217 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
actin filament polymerization GO:0030041 2 0.018
regulation of cellular ketone metabolic process GO:0010565 7 0.018
regulation of neurogenesis GO:0050767 87 0.018
Rat
actin filament based movement GO:0030048 1 0.018
regulation of muscle contraction GO:0006937 3 0.018
regulation of erk1 and erk2 cascade GO:0070372 4 0.018
response to stress GO:0006950 263 0.018
single organism localization GO:1902578 225 0.018
regulation of anatomical structure morphogenesis GO:0022603 130 0.018
Rat
regulation of mrna splicing via spliceosome GO:0048024 3 0.018
ribonucleoside monophosphate catabolic process GO:0009158 4 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
regulation of cell activation GO:0050865 1 0.018
hepaticobiliary system development GO:0061008 98 0.018
regulation of signaling GO:0023051 235 0.018
regulation of response to extracellular stimulus GO:0032104 1 0.018
protein heterooligomerization GO:0051291 1 0.018
regionalization GO:0003002 274 0.018
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.018
biosynthetic process GO:0009058 294 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.017
Rat
nuclear transport GO:0051169 4 0.017
leukocyte proliferation GO:0070661 1 0.017
rhombomere 5 development GO:0021571 4 0.017
antimicrobial humoral response GO:0019730 2 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.017
negative regulation of protein kinase activity GO:0006469 4 0.017
cellular component biogenesis GO:0044085 178 0.017
regulation of synaptic plasticity GO:0048167 1 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
liver development GO:0001889 96 0.017
peptidyl threonine modification GO:0018210 1 0.017
modification dependent macromolecule catabolic process GO:0043632 3 0.017
digestive system development GO:0055123 289 0.017
response to external stimulus GO:0009605 264 0.017
digestive tract development GO:0048565 265 0.017
b cell activation GO:0042113 2 0.017
nucleic acid metabolic process GO:0090304 244 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
somatic muscle development GO:0007525 4 0.016
proteasomal protein catabolic process GO:0010498 2 0.016
establishment of protein localization to plasma membrane GO:0090002 1 0.016
gtp metabolic process GO:0046039 4 0.016
cellular response to radiation GO:0071478 4 0.016
retina development in camera type eye GO:0060041 146 0.016
regulation of nitrogen compound metabolic process GO:0051171 251 0.016
regulation of cytoplasmic transport GO:1903649 4 0.016
cellular protein catabolic process GO:0044257 4 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
negative regulation of kinase activity GO:0033673 4 0.016
maternal determination of anterior posterior axis embryo GO:0008358 4 0.016
peptidyl serine modification GO:0018209 2 0.016
positive regulation of biological process GO:0048518 253 0.016
peptidyl serine phosphorylation GO:0018105 1 0.016
regulation of protein transport GO:0051223 3 0.016
regulation of transmembrane transporter activity GO:0022898 2 0.016
cytoplasm organization GO:0007028 4 0.016
negative regulation of catabolic process GO:0009895 3 0.016
regulation of cell projection assembly GO:0060491 4 0.016
rna metabolic process GO:0016070 219 0.016
aromatic compound biosynthetic process GO:0019438 217 0.016
ubiquitin dependent protein catabolic process GO:0006511 3 0.016
blood vessel morphogenesis GO:0048514 216 0.016
forebrain cell migration GO:0021885 1 0.016
organonitrogen compound metabolic process GO:1901564 74 0.016
angiogenesis GO:0001525 158 0.016
nucleocytoplasmic transport GO:0006913 4 0.016
regulation of transporter activity GO:0032409 2 0.015
establishment of synaptic vesicle localization GO:0097480 1 0.015
determination of bilateral symmetry GO:0009855 204 0.015
inner ear development GO:0048839 126 0.015
heart development GO:0007507 313 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
mononuclear cell proliferation GO:0032943 1 0.015
female meiotic division GO:0007143 2 0.015
regulation of multicellular organismal development GO:2000026 223 0.015
Rat
lipid catabolic process GO:0016042 4 0.015
single organism nuclear import GO:1902593 3 0.015
nuclear import GO:0051170 3 0.015
cellular response to chemical stimulus GO:0070887 157 0.015
cellular amide metabolic process GO:0043603 4 0.015
regulation of filopodium assembly GO:0051489 2 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
neurotransmitter secretion GO:0007269 2 0.015
development of primary female sexual characteristics GO:0046545 4 0.015
dorsal ventral pattern formation GO:0009953 125 0.015
carboxylic acid metabolic process GO:0019752 22 0.015
nucleoside monophosphate catabolic process GO:0009125 4 0.015
nuclear migration GO:0007097 3 0.014
alternative mrna splicing via spliceosome GO:0000380 1 0.014
nerve development GO:0021675 45 0.014
gastrulation GO:0007369 208 0.014
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.014
modification dependent protein catabolic process GO:0019941 3 0.014
regulation of neural precursor cell proliferation GO:2000177 3 0.014
secondary metabolic process GO:0019748 3 0.014
hatching GO:0035188 4 0.014
growth GO:0040007 174 0.014
sleep GO:0030431 1 0.014
regulation of autophagy GO:0010506 3 0.014
axon extension GO:0048675 45 0.014
regulation of ph GO:0006885 3 0.014
heterocycle metabolic process GO:0046483 290 0.014
camera type eye morphogenesis GO:0048593 108 0.014
protein import GO:0017038 3 0.014
hemopoiesis GO:0030097 183 0.014
cellular amino acid metabolic process GO:0006520 7 0.014
cell aging GO:0007569 2 0.014
organism emergence from protective structure GO:0071684 4 0.014
negative regulation of mapk cascade GO:0043409 4 0.014
germ line stem cell maintenance GO:0030718 2 0.014
retina morphogenesis in camera type eye GO:0060042 79 0.014
axon guidance GO:0007411 86 0.014
spermatid development GO:0007286 2 0.014
lamellipodium assembly GO:0030032 1 0.014
positive regulation of ras protein signal transduction GO:0046579 1 0.014
endocrine system development GO:0035270 65 0.014
transcription from rna polymerase ii promoter GO:0006366 80 0.014
regulation of meiotic cell cycle GO:0051445 1 0.014
spermatid differentiation GO:0048515 2 0.014
startle response GO:0001964 4 0.014
peptidyl threonine phosphorylation GO:0018107 1 0.014
regulation of developmental process GO:0050793 247 0.014
Rat
intracellular mrna localization GO:0008298 1 0.014
regulation of microtubule cytoskeleton organization GO:0070507 3 0.014
synaptic transmission cholinergic GO:0007271 4 0.014
cortical cytoskeleton organization GO:0030865 1 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
regulation of cell communication GO:0010646 232 0.013
purine nucleoside monophosphate catabolic process GO:0009128 4 0.013
cellular respiration GO:0045333 3 0.013
oocyte anterior posterior axis specification GO:0007314 4 0.013
protein localization to nucleus GO:0034504 3 0.013
macromolecule biosynthetic process GO:0009059 227 0.013
endosomal transport GO:0016197 2 0.013
protein metabolic process GO:0019538 183 0.013
negative regulation of synapse assembly GO:0051964 2 0.013
cellular aromatic compound metabolic process GO:0006725 295 0.013
response to uv GO:0009411 3 0.013
immune system development GO:0002520 191 0.013
macroautophagy GO:0016236 1 0.013
specification of symmetry GO:0009799 204 0.013
glial cell migration GO:0008347 3 0.013
response to carbohydrate GO:0009743 3 0.013
regulation of signal transduction GO:0009966 225 0.013
cellular component assembly GO:0022607 170 0.013
organic acid metabolic process GO:0006082 31 0.013
chemotaxis GO:0006935 104 0.013
gland development GO:0048732 143 0.013
embryonic skeletal system development GO:0048706 97 0.013
embryonic skeletal system morphogenesis GO:0048704 93 0.013
developmental cell growth GO:0048588 52 0.013
regulation of stem cell differentiation GO:2000736 4 0.013
meiotic cell cycle process GO:1903046 3 0.013
protein import into nucleus GO:0006606 3 0.013
developmental growth involved in morphogenesis GO:0060560 86 0.013
regulation of cellular biosynthetic process GO:0031326 245 0.013
pole plasm assembly GO:0007315 4 0.013
macromolecular complex disassembly GO:0032984 1 0.013
protein targeting to nucleus GO:0044744 3 0.013
organic substance biosynthetic process GO:1901576 289 0.013
regulation of purine nucleotide catabolic process GO:0033121 2 0.013
ear development GO:0043583 127 0.013
regulation of neuronal synaptic plasticity GO:0048168 1 0.013
negative regulation of reproductive process GO:2000242 3 0.013
lymphocyte proliferation GO:0046651 1 0.013
positive regulation of small gtpase mediated signal transduction GO:0051057 1 0.013
cytokinesis GO:0000910 3 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.013
single organism organelle organization GO:1902589 199 0.013
locus ceruleus development GO:0021703 3 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
cellular biosynthetic process GO:0044249 286 0.013
regulation of dendrite morphogenesis GO:0048814 3 0.012
cellular component disassembly GO:0022411 1 0.012
sequestering of calcium ion GO:0051208 3 0.012
neuron projection guidance GO:0097485 86 0.012
regulation of biosynthetic process GO:0009889 250 0.012
female gonad development GO:0008585 4 0.012
cellular nitrogen compound biosynthetic process GO:0044271 218 0.012
double strand break repair GO:0006302 3 0.012
cilium morphogenesis GO:0060271 85 0.012
regulation of response to nutrient levels GO:0032107 1 0.012
cell substrate adhesion GO:0031589 4 0.012
digestive tract morphogenesis GO:0048546 231 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.012
positive regulation of nucleotide catabolic process GO:0030813 1 0.012
negative regulation of sequestering of calcium ion GO:0051283 4 0.012
transport GO:0006810 220 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
golgi vesicle transport GO:0048193 3 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
response to monosaccharide GO:0034284 3 0.012
regulation of bone remodeling GO:0046850 2 0.012
female sex differentiation GO:0046660 4 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.012
epithelial cell morphogenesis GO:0003382 2 0.012
ear morphogenesis GO:0042471 64 0.012
positive regulation of camp metabolic process GO:0030816 2 0.012
fertilization GO:0009566 3 0.012
sensory system development GO:0048880 76 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
organelle fusion GO:0048284 3 0.012
response to glucocorticoid GO:0051384 1 0.012
regulation of tube size GO:0035150 2 0.012
protein complex disassembly GO:0043241 1 0.012
response to wounding GO:0009611 116 0.012
regulation of cell projection organization GO:0031344 44 0.012
Rat
cytoskeleton dependent cytokinesis GO:0061640 3 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
nuclear export GO:0051168 1 0.012
muscle cell differentiation GO:0042692 139 0.012
regulation of protein targeting GO:1903533 2 0.012
positive regulation of gtpase activity GO:0043547 1 0.011
regulation of cytokine production GO:0001817 3 0.011
regulation of binding GO:0051098 3 0.011
regulation of gtp catabolic process GO:0033124 2 0.011
regulation of nucleotide catabolic process GO:0030811 2 0.011
hormone transport GO:0009914 2 0.011
response to ketone GO:1901654 1 0.011
cellular component assembly involved in morphogenesis GO:0010927 107 0.011
regulation of inflammatory response GO:0050727 2 0.011
regulation of primary metabolic process GO:0080090 311 0.011
bone remodeling GO:0046849 2 0.011
cell fate specification GO:0001708 68 0.011
regulation of gtpase activity GO:0043087 2 0.011
positive regulation of secretion GO:0051047 1 0.011
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.011
cellular nitrogen compound metabolic process GO:0034641 290 0.011
cilium assembly GO:0042384 58 0.011
regulation of metal ion transport GO:0010959 4 0.011
nucleobase containing compound transport GO:0015931 2 0.011
cilium organization GO:0044782 71 0.011
post embryonic organ development GO:0048569 4 0.011
long chain fatty acid metabolic process GO:0001676 1 0.011
negative regulation of protein transport GO:0051224 3 0.011
protein stabilization GO:0050821 2 0.011
regulation of metabolic process GO:0019222 359 0.011
stem cell fate commitment GO:0048865 1 0.011
response to corticosteroid GO:0031960 1 0.011
catechol containing compound metabolic process GO:0009712 2 0.011
cellular response to decreased oxygen levels GO:0036294 1 0.011
protein acetylation GO:0006473 2 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 22 0.011
neurological system process GO:0050877 62 0.011
heart contraction GO:0060047 71 0.011
taxis GO:0042330 109 0.011
embryo development ending in birth or egg hatching GO:0009792 271 0.011
determination of left right symmetry GO:0007368 179 0.011
cell matrix adhesion GO:0007160 4 0.011
peptide metabolic process GO:0006518 1 0.011
regulation of nucleocytoplasmic transport GO:0046822 2 0.011
epithelial cell differentiation GO:0030855 116 0.011
response to antibiotic GO:0046677 1 0.011
mitochondrial transport GO:0006839 2 0.011
heterocycle biosynthetic process GO:0018130 215 0.011
centrosome organization GO:0051297 1 0.011
ovulation cycle process GO:0022602 2 0.011
cellular protein metabolic process GO:0044267 129 0.011
blood circulation GO:0008015 87 0.011
regulation of exocytosis GO:0017157 1 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
sympathetic nervous system development GO:0048485 3 0.011
stem cell division GO:0017145 1 0.011
multicellular organismal response to stress GO:0033555 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
regulation of macromolecule biosynthetic process GO:0010556 225 0.011
lamellipodium organization GO:0097581 1 0.010
regulation of postsynaptic membrane potential GO:0060078 1 0.010
nucleobase containing compound biosynthetic process GO:0034654 205 0.010
peptide transport GO:0015833 1 0.010
negative regulation of cellular catabolic process GO:0031330 3 0.010
melanin metabolic process GO:0006582 2 0.010
circulatory system process GO:0003013 87 0.010
protein secretion GO:0009306 1 0.010
g protein coupled receptor signaling pathway GO:0007186 74 0.010
protein targeting to membrane GO:0006612 1 0.010
response to hydrogen peroxide GO:0042542 3 0.010
post golgi vesicle mediated transport GO:0006892 1 0.010
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of blood pressure GO:0008217 1 0.010
negative regulation of translation GO:0017148 1 0.010
response to hexose GO:0009746 3 0.010
response to alkaloid GO:0043279 2 0.010
regulation of dna replication GO:0006275 3 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
protein modification process GO:0036211 100 0.010
hematopoietic or lymphoid organ development GO:0048534 191 0.010
regulation of rna metabolic process GO:0051252 224 0.010
cytosolic calcium ion transport GO:0060401 3 0.010
cranial nerve development GO:0021545 42 0.010
gene expression GO:0010467 252 0.010
positive regulation of secretion by cell GO:1903532 1 0.010
fin development GO:0033333 77 0.010
kupffer s vesicle development GO:0070121 50 0.010
cellular carbohydrate metabolic process GO:0044262 4 0.010
regulation of circadian rhythm GO:0042752 4 0.010
regulation of cellular component movement GO:0051270 55 0.010
calcium mediated signaling GO:0019722 2 0.010

rufy3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.020
disease of cellular proliferation DOID:14566 0 0.017
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.014
immune system disease DOID:2914 0 0.011
musculoskeletal system disease DOID:17 0 0.010