Danio rerio

35 known processes

acvrl1

activin A receptor type II-like 1

(Aliases: zehn1109,hm:zehn1109,vgb,alk1)

acvrl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel morphogenesis GO:0048514 216 0.609
blood vessel development GO:0001568 246 0.519
vasculature development GO:0001944 278 0.446
angiogenesis GO:0001525 158 0.294
Mouse
ameboidal type cell migration GO:0001667 143 0.236
Zebrafish
signal transduction GO:0007165 455 0.212
Zebrafish Mouse Rat Fly
regulation of biological quality GO:0065008 263 0.201
cell motility GO:0048870 244 0.183
Zebrafish
localization of cell GO:0051674 244 0.137
Zebrafish
patterning of blood vessels GO:0001569 15 0.117
regulation of signaling GO:0023051 235 0.114
Zebrafish Mouse Fly
sprouting angiogenesis GO:0002040 53 0.104
regulation of vasculature development GO:1901342 33 0.100
Mouse
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.097
regulation of cell communication GO:0010646 232 0.095
Zebrafish Mouse Fly
taxis GO:0042330 109 0.091
endosomal transport GO:0016197 2 0.086
response to chemical GO:0042221 320 0.078
Mouse Rat Fly
ubiquitin dependent protein catabolic process GO:0006511 3 0.076
positive regulation of biological process GO:0048518 253 0.074
Mouse Worm Fly
protein metabolic process GO:0019538 183 0.073
Zebrafish Rat Worm Fly
cellular protein catabolic process GO:0044257 4 0.072
morphogenesis of an epithelium GO:0002009 333 0.071
Zebrafish
axonogenesis GO:0007409 152 0.067
death GO:0016265 121 0.064
lymph vessel development GO:0001945 27 0.060
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.060
cellular protein metabolic process GO:0044267 129 0.060
Zebrafish Rat Fly
negative regulation of biological process GO:0048519 304 0.059
Zebrafish Mouse Fly
synaptic vesicle transport GO:0048489 1 0.056
epithelium migration GO:0090132 25 0.056
establishment of localization GO:0051234 244 0.055
regulation of multicellular organismal process GO:0051239 277 0.053
Mouse Worm Fly
response to stress GO:0006950 263 0.053
morphogenesis of a branching epithelium GO:0061138 16 0.051
single organism transport GO:0044765 206 0.050
larval development GO:0002164 2 0.049
Worm
tissue migration GO:0090130 37 0.049
intramembranous ossification GO:0001957 3 0.048
regulation of cell death GO:0010941 103 0.048
actin cytoskeleton organization GO:0030036 63 0.046
Fly
proteasomal protein catabolic process GO:0010498 2 0.045
regulation of signal transduction GO:0009966 225 0.045
Zebrafish Mouse Fly
spindle assembly involved in mitosis GO:0090307 1 0.043
nuclear transport GO:0051169 4 0.043
single organism localization GO:1902578 225 0.043
Worm
response to organic substance GO:0010033 153 0.043
Mouse Rat Fly
regulation of cellular metabolic process GO:0031323 320 0.042
Zebrafish Mouse Worm Fly
regulation of protein complex assembly GO:0043254 3 0.042
regulation of synapse organization GO:0050807 3 0.041
Fly
endothelial cell migration GO:0043542 19 0.041
cognition GO:0050890 1 0.040
transport GO:0006810 220 0.040
cellular response to chemical stimulus GO:0070887 157 0.039
Mouse Rat Fly
cellular component movement GO:0006928 335 0.038
Zebrafish
cell death GO:0008219 121 0.038
regulation of cellular response to growth factor stimulus GO:0090287 35 0.038
Fly
response to external stimulus GO:0009605 264 0.038
Worm Fly
macromolecular complex disassembly GO:0032984 1 0.037
regulation of endothelial cell proliferation GO:0001936 1 0.037
Mouse
protein complex disassembly GO:0043241 1 0.036
aging GO:0007568 2 0.035
response to abiotic stimulus GO:0009628 122 0.035
branching morphogenesis of an epithelial tube GO:0048754 15 0.034
neuron projection development GO:0031175 180 0.034
embryonic organ morphogenesis GO:0048562 274 0.034
Zebrafish
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.034
negative regulation of cellular process GO:0048523 283 0.033
Zebrafish Mouse Fly
intracellular signal transduction GO:0035556 85 0.033
Rat
cellular component disassembly GO:0022411 1 0.033
cellular response to organic substance GO:0071310 105 0.032
Mouse Rat Fly
heart development GO:0007507 313 0.031
Zebrafish
organelle organization GO:0006996 227 0.031
Fly
regulation of angiogenesis GO:0045765 26 0.031
Mouse
macrophage chemotaxis GO:0048246 3 0.031
smooth muscle contraction GO:0006939 2 0.030
regulation of cytoplasmic transport GO:1903649 4 0.030
regulation of microtubule cytoskeleton organization GO:0070507 3 0.030
immune system development GO:0002520 191 0.030
Zebrafish
cellular component biogenesis GO:0044085 178 0.030
Zebrafish Rat Fly
regulation of apoptotic process GO:0042981 98 0.030
multicellular organismal signaling GO:0035637 22 0.030
positive regulation of endothelial cell proliferation GO:0001938 1 0.030
Mouse
cellular component assembly GO:0022607 170 0.029
Zebrafish Rat Fly
cellular protein modification process GO:0006464 100 0.029
Zebrafish Rat Fly
meiotic nuclear division GO:0007126 4 0.029
hematopoietic or lymphoid organ development GO:0048534 191 0.029
Zebrafish
stem cell proliferation GO:0072089 4 0.029
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.029
protein localization to nucleus GO:0034504 3 0.029
Worm
innate immune response GO:0045087 13 0.029
Worm Fly
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.029
chemotaxis GO:0006935 104 0.029
modification dependent macromolecule catabolic process GO:0043632 3 0.029
programmed cell death GO:0012501 119 0.028
single organism metabolic process GO:0044710 217 0.028
Rat
protein modification process GO:0036211 100 0.028
Zebrafish Rat Fly
establishment of protein localization to organelle GO:0072594 4 0.028
centrosome organization GO:0051297 1 0.028
regulation of cell shape GO:0008360 1 0.028
single organism intracellular transport GO:1902582 25 0.028
small molecule metabolic process GO:0044281 77 0.028
synaptic vesicle localization GO:0097479 1 0.028
establishment of synaptic vesicle localization GO:0097480 1 0.027
segmentation GO:0035282 97 0.026
Fly
negative regulation of leukocyte chemotaxis GO:0002689 3 0.026
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.026
macromolecule modification GO:0043412 111 0.025
Zebrafish Rat Fly
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.025
phosphorus metabolic process GO:0006793 109 0.025
Zebrafish Rat Fly
single organism organelle organization GO:1902589 199 0.025
Fly
release of sequestered calcium ion into cytosol GO:0051209 3 0.025
modification dependent protein catabolic process GO:0019941 3 0.025
cellular component morphogenesis GO:0032989 336 0.025
Worm
negative regulation of programmed cell death GO:0043069 58 0.024
cell surface receptor signaling pathway GO:0007166 325 0.024
Zebrafish Mouse Rat Fly
embryonic organ development GO:0048568 381 0.024
Zebrafish
axon development GO:0061564 166 0.024
negative regulation of angiogenesis GO:0016525 7 0.024
stem cell maintenance GO:0019827 4 0.023
Fly
embryonic viscerocranium morphogenesis GO:0048703 52 0.023
intracellular transport GO:0046907 32 0.023
direct ossification GO:0036072 3 0.023
regulation of establishment of protein localization GO:0070201 4 0.023
protein import into nucleus GO:0006606 3 0.023
system process GO:0003008 185 0.023
cell part morphogenesis GO:0032990 246 0.022
apoptotic process GO:0006915 116 0.022
anterior posterior pattern specification GO:0009952 152 0.022
Zebrafish Fly
positive regulation of immune effector process GO:0002699 3 0.022
cytoskeleton organization GO:0007010 96 0.022
Fly
neuron projection morphogenesis GO:0048812 161 0.022
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.022
neutrophil migration GO:1990266 10 0.021
cellular response to oxygen levels GO:0071453 1 0.021
regulation of response to stimulus GO:0048583 269 0.021
Zebrafish Mouse Fly
establishment of localization in cell GO:0051649 77 0.021
establishment of endothelial barrier GO:0061028 3 0.021
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.021
chordate embryonic development GO:0043009 271 0.021
Mouse
skeletal system development GO:0001501 181 0.021
Zebrafish
nuclear export GO:0051168 1 0.021
cell morphogenesis GO:0000902 289 0.021
Worm
negative regulation of epithelial cell migration GO:0010633 1 0.021
glial cell migration GO:0008347 3 0.021
blood vessel endothelial cell migration GO:0043534 18 0.020
phosphate containing compound metabolic process GO:0006796 108 0.020
Zebrafish Rat Fly
multicellular organismal metabolic process GO:0044236 2 0.020
synaptic vesicle recycling GO:0036465 1 0.020
regulation of binding GO:0051098 3 0.020
regulation of multicellular organismal development GO:2000026 223 0.020
Mouse Fly
cellular response to starvation GO:0009267 1 0.019
mononuclear cell proliferation GO:0032943 1 0.019
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.019
gtp metabolic process GO:0046039 4 0.019
regulation of peptidase activity GO:0052547 23 0.019
regulation of mesenchymal cell proliferation GO:0010464 1 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
guanosine containing compound metabolic process GO:1901068 4 0.019
neuronal action potential GO:0019228 18 0.019
epithelial tube morphogenesis GO:0060562 148 0.019
Zebrafish
mitochondrion organization GO:0007005 4 0.019
regulation of cytokine production GO:0001817 3 0.018
convergent extension involved in gastrulation GO:0060027 71 0.018
Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.018
Zebrafish Mouse Worm
negative regulation of protein complex assembly GO:0031333 1 0.018
epithelial cell migration GO:0010631 25 0.018
regulation of blood pressure GO:0008217 1 0.018
embryonic skeletal system morphogenesis GO:0048704 93 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
Fly
sensory organ development GO:0007423 393 0.018
Mouse
gene expression GO:0010467 252 0.018
Zebrafish Mouse Worm
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.018
regulation of protein binding GO:0043393 3 0.018
regulation of programmed cell death GO:0043067 101 0.017
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.017
cellular amine metabolic process GO:0044106 2 0.017
phosphorylation GO:0016310 69 0.017
Zebrafish Rat Fly
actin mediated cell contraction GO:0070252 1 0.017
action potential GO:0001508 19 0.017
regulation of systemic arterial blood pressure GO:0003073 1 0.017
cellular amino acid metabolic process GO:0006520 7 0.017
positive regulation of gtpase activity GO:0043547 1 0.017
spindle assembly GO:0051225 2 0.017
embryonic skeletal system development GO:0048706 97 0.017
cartilage development GO:0051216 96 0.017
Zebrafish
protein dephosphorylation GO:0006470 3 0.017
cell morphogenesis involved in differentiation GO:0000904 195 0.017
glial cell differentiation GO:0010001 42 0.017
cell cycle process GO:0022402 53 0.017
macromolecular complex subunit organization GO:0043933 74 0.017
Zebrafish Rat Fly
protein targeting to nucleus GO:0044744 3 0.016
inositol lipid mediated signaling GO:0048017 2 0.016
cell migration GO:0016477 237 0.016
Zebrafish
peptidyl lysine acetylation GO:0018394 2 0.016
regulation of protein localization to nucleus GO:1900180 2 0.016
organelle assembly GO:0070925 110 0.016
regulation of phosphate metabolic process GO:0019220 43 0.016
generation of neurons GO:0048699 385 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
cytokinesis GO:0000910 3 0.016
regulation of developmental process GO:0050793 247 0.016
Mouse Worm Fly
gtp catabolic process GO:0006184 2 0.016
negative regulation of apoptotic process GO:0043066 55 0.016
negative regulation of neutrophil chemotaxis GO:0090024 3 0.016
erk1 and erk2 cascade GO:0070371 4 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
positive regulation of cell communication GO:0010647 56 0.015
Mouse
regulation of protein complex disassembly GO:0043244 1 0.015
inner ear development GO:0048839 126 0.015
organic acid metabolic process GO:0006082 31 0.015
regulation of protein depolymerization GO:1901879 1 0.015
mechanosensory behavior GO:0007638 2 0.015
protein localization to plasma membrane GO:0072659 1 0.015
positive regulation of cellular process GO:0048522 201 0.015
Mouse Worm Fly
regulation of inflammatory response GO:0050727 2 0.015
ear development GO:0043583 127 0.015
regulation of cellular protein catabolic process GO:1903362 1 0.015
regulation of gtp catabolic process GO:0033124 2 0.015
reactive nitrogen species metabolic process GO:2001057 0 0.015
cellular response to external stimulus GO:0071496 2 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
neuron neuron synaptic transmission GO:0007270 1 0.015
proteolysis GO:0006508 38 0.015
cellular localization GO:0051641 97 0.015
Worm
nucleobase containing small molecule metabolic process GO:0055086 32 0.015
regulation of wnt signaling pathway GO:0030111 53 0.015
golgi organization GO:0007030 1 0.015
protein phosphorylation GO:0006468 47 0.015
Zebrafish Rat Fly
rna localization GO:0006403 4 0.015
regulation of cell projection assembly GO:0060491 4 0.015
negative regulation of cell death GO:0060548 60 0.015
lymphoid lineage cell migration into thymus GO:0097535 4 0.015
internal protein amino acid acetylation GO:0006475 2 0.014
single organism nuclear import GO:1902593 3 0.014
germ line stem cell maintenance GO:0030718 2 0.014
Fly
microtubule organizing center organization GO:0031023 1 0.014
multicellular organismal macromolecule metabolic process GO:0044259 2 0.014
regulation of phosphorus metabolic process GO:0051174 43 0.014
calcium mediated signaling GO:0019722 2 0.014
synaptic growth at neuromuscular junction GO:0051124 2 0.014
Fly
regulation of vasculogenesis GO:2001212 1 0.014
fin regeneration GO:0031101 51 0.014
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.014
Zebrafish Mouse Worm
positive regulation of apoptotic signaling pathway GO:2001235 1 0.014
cellular protein complex disassembly GO:0043624 1 0.014
regulation of blood vessel size GO:0050880 2 0.014
positive regulation of muscle cell differentiation GO:0051149 1 0.014
organelle localization GO:0051640 49 0.014
convergent extension GO:0060026 118 0.014
Zebrafish
venous blood vessel morphogenesis GO:0048845 3 0.014
regulation of protein targeting GO:1903533 2 0.014
ribonucleoside monophosphate catabolic process GO:0009158 4 0.014
eye development GO:0001654 277 0.014
Mouse
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.014
positive regulation of macromolecule metabolic process GO:0010604 93 0.013
Mouse Worm
regulation of organ growth GO:0046620 3 0.013
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.013
regulation of cellular component organization GO:0051128 86 0.013
Worm Fly
regulation of skeletal muscle cell differentiation GO:2001014 1 0.013
renal system development GO:0072001 94 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
actin filament polymerization GO:0030041 2 0.013
tissue remodeling GO:0048771 4 0.013
Mouse
morphogenesis of a branching structure GO:0001763 21 0.013
cell projection organization GO:0030030 284 0.013
gliogenesis GO:0042063 45 0.013
positive regulation of positive chemotaxis GO:0050927 4 0.013
cell projection morphogenesis GO:0048858 244 0.013
regulation of response to stress GO:0080134 36 0.013
Fly
g protein coupled receptor signaling pathway GO:0007186 74 0.013
cardiac atrium morphogenesis GO:0003209 2 0.013
b cell activation GO:0042113 2 0.013
transmission of nerve impulse GO:0019226 19 0.013
homeostatic process GO:0042592 142 0.013
positive regulation of transport GO:0051050 2 0.013
cytosolic calcium ion transport GO:0060401 3 0.013
vasculogenesis GO:0001570 41 0.012
positive regulation of cell cycle GO:0045787 3 0.012
lymphocyte proliferation GO:0046651 1 0.012
golgi vesicle transport GO:0048193 3 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
nuclear import GO:0051170 3 0.012
organonitrogen compound metabolic process GO:1901564 74 0.012
positive regulation of secretion GO:0051047 1 0.012
positive regulation of map kinase activity GO:0043406 3 0.012
regulation of anatomical structure morphogenesis GO:0022603 130 0.012
Mouse Worm
cellular ketone metabolic process GO:0042180 11 0.012
actin polymerization or depolymerization GO:0008154 2 0.012
phagocytosis GO:0006909 3 0.012
regulation of cell matrix adhesion GO:0001952 1 0.012
amine metabolic process GO:0009308 2 0.012
response to hexose GO:0009746 3 0.012
positive regulation of cytoskeleton organization GO:0051495 3 0.012
myelin assembly GO:0032288 1 0.012
protein import GO:0017038 3 0.012
cellular response to extracellular stimulus GO:0031668 2 0.012
response to external biotic stimulus GO:0043207 97 0.012
Worm Fly
wound healing GO:0042060 90 0.012
Zebrafish
enzyme linked receptor protein signaling pathway GO:0007167 106 0.012
Zebrafish Mouse Rat Fly
regulation of cellular ketone metabolic process GO:0010565 7 0.011
protein acetylation GO:0006473 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
intracellular mrna localization GO:0008298 1 0.011
response to other organism GO:0051707 97 0.011
Worm Fly
microtubule depolymerization GO:0007019 1 0.011
carboxylic acid metabolic process GO:0019752 22 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
antimicrobial humoral response GO:0019730 2 0.011
establishment of organelle localization GO:0051656 45 0.011
nucleoside monophosphate catabolic process GO:0009125 4 0.011
protein polymerization GO:0051258 4 0.011
regulation of cellular component movement GO:0051270 55 0.011
meiotic chromosome segregation GO:0045132 3 0.011
regulation of gtpase activity GO:0043087 2 0.011
regulation of cellular amine metabolic process GO:0033238 0 0.011
cilium organization GO:0044782 71 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of skeletal muscle tissue development GO:0048641 4 0.011
leukocyte proliferation GO:0070661 1 0.011
nucleobase containing compound metabolic process GO:0006139 274 0.011
Zebrafish Mouse Worm
synaptic vesicle endocytosis GO:0048488 1 0.011
nucleoside phosphate metabolic process GO:0006753 28 0.011
immune system process GO:0002376 241 0.011
Zebrafish Worm Fly
cytoplasm organization GO:0007028 4 0.011
regulation of synapse assembly GO:0051963 3 0.011
Fly
regulation of bone mineralization GO:0030500 2 0.011
positive regulation of nucleotide catabolic process GO:0030813 1 0.011
pole plasm assembly GO:0007315 4 0.011
response to decreased oxygen levels GO:0036293 25 0.011
regulation of defense response GO:0031347 14 0.011
Fly
cardiac atrium development GO:0003230 4 0.011
Zebrafish
cellular response to nutrient levels GO:0031669 2 0.011
actin filament based process GO:0030029 64 0.011
Fly
embryonic cranial skeleton morphogenesis GO:0048701 90 0.010
protein acylation GO:0043543 3 0.010
regulation of intracellular signal transduction GO:1902531 57 0.010
negative regulation of endothelial cell migration GO:0010596 1 0.010
positive regulation of cellular catabolic process GO:0031331 3 0.010
cellular response to radiation GO:0071478 4 0.010
pericardium development GO:0060039 1 0.010
negative regulation of proteolysis GO:0045861 10 0.010
positive regulation of gtp catabolic process GO:0033126 1 0.010
regulation of protein transport GO:0051223 3 0.010
endothelial cell development GO:0001885 12 0.010
cell chemotaxis GO:0060326 17 0.010
response to fluid shear stress GO:0034405 2 0.010
myeloid leukocyte migration GO:0097529 12 0.010
single organism cellular localization GO:1902580 46 0.010
regionalization GO:0003002 274 0.010
regulation of protein import into nucleus GO:0042306 2 0.010
negative regulation of blood vessel endothelial cell migration GO:0043537 1 0.010
axon guidance GO:0007411 86 0.010
outflow tract morphogenesis GO:0003151 1 0.010
regulation of chondrocyte differentiation GO:0032330 1 0.010
cortical cytoskeleton organization GO:0030865 1 0.010

acvrl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.039
nervous system disease DOID:863 0 0.034