Danio rerio

18 known processes

col11a2

collagen type XI alpha-2

(Aliases: col11a1)

col11a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
notochord development GO:0030903 54 0.921
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.915
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.885
mediolateral intercalation GO:0060031 3 0.823
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.787
hepatic duct development GO:0061011 2 0.776
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.766
embryonic organ morphogenesis GO:0048562 274 0.740
chondrocyte development GO:0002063 4 0.641
specification of organ axis polarity GO:0010084 2 0.638
sequestering of calcium ion GO:0051208 3 0.598
skeletal system development GO:0001501 181 0.568
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.566
embryonic organ development GO:0048568 381 0.504
Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.491
optic placode formation GO:0001743 4 0.427
thrombocyte differentiation GO:0002574 4 0.403
sequestering of metal ion GO:0051238 3 0.350
sensory perception of mechanical stimulus GO:0050954 16 0.348
Mouse
optic placode formation involved in camera type eye formation GO:0046619 3 0.327
fin morphogenesis GO:0033334 53 0.325
Zebrafish
anterior head development GO:0097065 2 0.323
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.304
sensory organ morphogenesis GO:0090596 200 0.299
heart morphogenesis GO:0003007 156 0.298
extracellular structure organization GO:0043062 27 0.279
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.277
chondrocyte differentiation GO:0002062 7 0.276
Mouse
regulation of anterior head development GO:2000742 2 0.267
establishment of protein localization to organelle GO:0072594 4 0.260
embryonic camera type eye formation GO:0060900 10 0.255
cartilage condensation GO:0001502 3 0.243
ion homeostasis GO:0050801 41 0.241
embryo development ending in birth or egg hatching GO:0009792 271 0.238
regulation of sequestering of calcium ion GO:0051282 4 0.234
fin regeneration GO:0031101 51 0.231
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.223
cartilage morphogenesis GO:0060536 13 0.208
inner ear morphogenesis GO:0042472 63 0.203
embryonic skeletal system development GO:0048706 97 0.198
spinal cord anterior posterior patterning GO:0021512 1 0.186
embryonic neurocranium morphogenesis GO:0048702 15 0.185
sensory organ development GO:0007423 393 0.180
hepatocyte proliferation GO:0072574 2 0.175
skeletal system morphogenesis GO:0048705 102 0.165
Mouse
embryonic digestive tract development GO:0048566 4 0.161
proteoglycan metabolic process GO:0006029 14 0.158
developmental growth GO:0048589 166 0.153
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.151
cartilage development GO:0051216 96 0.139
negative regulation of sequestering of calcium ion GO:0051283 4 0.121
negative regulation of cell communication GO:0010648 96 0.121
chordate embryonic development GO:0043009 271 0.117
growth plate cartilage development GO:0003417 2 0.117
cellular response to external stimulus GO:0071496 2 0.116
embryonic digestive tract morphogenesis GO:0048557 3 0.112
negative regulation of signaling GO:0023057 96 0.112
negative regulation of wnt signaling pathway GO:0030178 30 0.110
organelle localization GO:0051640 49 0.108
cell morphogenesis GO:0000902 289 0.107
gastrulation GO:0007369 208 0.107
wound healing GO:0042060 90 0.107
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.106
calcium ion homeostasis GO:0055074 19 0.105
embryonic heart tube development GO:0035050 133 0.101
endodermal digestive tract morphogenesis GO:0061031 2 0.098
growth plate cartilage morphogenesis GO:0003422 1 0.098
somitogenesis GO:0001756 87 0.097
cation homeostasis GO:0055080 33 0.094
gall bladder development GO:0061010 1 0.093
rostrocaudal neural tube patterning GO:0021903 29 0.089
fin development GO:0033333 77 0.088
Zebrafish
axon extension involved in axon guidance GO:0048846 10 0.088
connective tissue development GO:0061448 99 0.086
protein targeting to nucleus GO:0044744 3 0.086
regulation of cell communication GO:0010646 232 0.086
epithalamus development GO:0021538 10 0.085
heterocycle biosynthetic process GO:0018130 215 0.084
heart looping GO:0001947 94 0.082
release of sequestered calcium ion into cytosol GO:0051209 3 0.080
regulation of signaling GO:0023051 235 0.079
negative regulation of signal transduction GO:0009968 94 0.078
response to radiation GO:0009314 51 0.076
endochondral bone growth GO:0003416 2 0.075
specification of symmetry GO:0009799 204 0.075
specification of axis polarity GO:0065001 4 0.074
fertilization GO:0009566 3 0.072
neural plate development GO:0001840 10 0.071
tissue regeneration GO:0042246 74 0.071
Zebrafish
ear morphogenesis GO:0042471 64 0.069
determination of heart left right asymmetry GO:0061371 117 0.068
morphogenesis of an epithelium GO:0002009 333 0.068
response to external stimulus GO:0009605 264 0.068
Zebrafish
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.066
regulation of cellular response to growth factor stimulus GO:0090287 35 0.064
calcium ion transport into cytosol GO:0060402 3 0.063
protein import GO:0017038 3 0.062
swim bladder development GO:0048794 19 0.062
cell aggregation GO:0098743 3 0.061
appendage development GO:0048736 80 0.061
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.058
regulation of axon extension involved in axon guidance GO:0048841 6 0.057
muscle organ development GO:0007517 101 0.057
regulation of anatomical structure morphogenesis GO:0022603 130 0.057
tissue homeostasis GO:0001894 25 0.057
Mouse
divalent inorganic cation homeostasis GO:0072507 22 0.055
regulation of biomineral tissue development GO:0070167 2 0.054
protein import into nucleus GO:0006606 3 0.054
digestive tract development GO:0048565 265 0.053
establishment of mitotic spindle orientation GO:0000132 10 0.053
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.052
mesodermal cell fate commitment GO:0001710 14 0.050
growth GO:0040007 174 0.049
Zebrafish
ossification GO:0001503 23 0.049
Zebrafish
metal ion homeostasis GO:0055065 26 0.048
otic vesicle morphogenesis GO:0071600 34 0.047
epithelial cell morphogenesis GO:0003382 2 0.046
nuclear import GO:0051170 3 0.046
skeletal muscle tissue development GO:0007519 67 0.046
regulation of biological quality GO:0065008 263 0.046
Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.045
cellular protein catabolic process GO:0044257 4 0.045
detection of abiotic stimulus GO:0009582 24 0.045
digestive tract morphogenesis GO:0048546 231 0.044
regulation of bone mineralization GO:0030500 2 0.044
neural plate morphogenesis GO:0001839 7 0.044
otic vesicle formation GO:0030916 27 0.044
embryonic cranial skeleton morphogenesis GO:0048701 90 0.044
cytosolic calcium ion transport GO:0060401 3 0.043
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.042
muscle structure development GO:0061061 196 0.042
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.041
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.041
locomotion GO:0040011 313 0.041
neural tube patterning GO:0021532 33 0.040
axis elongation GO:0003401 31 0.040
response to organic cyclic compound GO:0014070 51 0.039
modification dependent protein catabolic process GO:0019941 3 0.039
response to wounding GO:0009611 116 0.038
Zebrafish
homeostatic process GO:0042592 142 0.038
Mouse
cellular component biogenesis GO:0044085 178 0.037
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.036
regulation of nitrogen compound metabolic process GO:0051171 251 0.036
single organism transport GO:0044765 206 0.036
cranial suture morphogenesis GO:0060363 1 0.036
embryonic skeletal joint development GO:0072498 3 0.036
cell migration involved in gastrulation GO:0042074 79 0.035
somite development GO:0061053 96 0.035
determination of bilateral symmetry GO:0009855 204 0.034
dorsal ventral neural tube patterning GO:0021904 1 0.034
heart development GO:0007507 313 0.033
cell morphogenesis involved in differentiation GO:0000904 195 0.033
nucleoside monophosphate catabolic process GO:0009125 4 0.033
phosphorus metabolic process GO:0006793 109 0.032
regulation of developmental growth GO:0048638 38 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
sensory system development GO:0048880 76 0.032
cellular component morphogenesis GO:0032989 336 0.032
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.030
formation of primary germ layer GO:0001704 62 0.030
intracellular transport GO:0046907 32 0.030
basement membrane assembly GO:0070831 3 0.029
cellular component assembly GO:0022607 170 0.029
dorsal convergence GO:0060030 14 0.028
lateral line system development GO:0048925 76 0.028
cellular homeostasis GO:0019725 26 0.028
response to alkaloid GO:0043279 2 0.028
vestibular receptor cell differentiation GO:0060114 3 0.028
protein localization to nucleus GO:0034504 3 0.028
cellular metal ion homeostasis GO:0006875 16 0.028
biomineral tissue development GO:0031214 13 0.028
regulation of protein targeting GO:1903533 2 0.028
single organismal cell cell adhesion GO:0016337 29 0.027
non canonical wnt signaling pathway GO:0035567 13 0.027
ribonucleoside monophosphate catabolic process GO:0009158 4 0.027
bone morphogenesis GO:0060349 11 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
organic substance biosynthetic process GO:1901576 289 0.026
regulation of jun kinase activity GO:0043506 3 0.026
transport GO:0006810 220 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
cellular macromolecule metabolic process GO:0044260 391 0.025
cell division GO:0051301 20 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
embryonic skeletal joint morphogenesis GO:0060272 3 0.025
regulation of mitotic cell cycle GO:0007346 25 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
endoderm development GO:0007492 49 0.025
chemical homeostasis GO:0048878 49 0.025
bmp signaling pathway GO:0030509 52 0.025
cell growth GO:0016049 57 0.025
aging GO:0007568 2 0.024
response to fibroblast growth factor GO:0071774 22 0.024
cellular divalent inorganic cation homeostasis GO:0072503 13 0.024
cellular response to organic cyclic compound GO:0071407 38 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
cell death GO:0008219 121 0.023
regulation of protein catabolic process GO:0042176 1 0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.023
lateral line development GO:0048882 66 0.022
tube morphogenesis GO:0035239 349 0.022
regulation of calcium ion transport GO:0051924 2 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
gastrulation with mouth forming second GO:0001702 44 0.021
inner ear development GO:0048839 126 0.021
regulation of tube size GO:0035150 2 0.021
habenula development GO:0021986 9 0.021
negative regulation of cellular process GO:0048523 283 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
cellular cation homeostasis GO:0030003 17 0.020
embryonic limb morphogenesis GO:0030326 2 0.019
positive regulation of catabolic process GO:0009896 4 0.019
unidimensional cell growth GO:0009826 5 0.019
cell migration GO:0016477 237 0.019
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.019
cellular localization GO:0051641 97 0.019
appendage morphogenesis GO:0035107 56 0.019
Zebrafish
negative regulation of mitosis GO:0045839 3 0.018
regulation of non canonical wnt signaling pathway GO:2000050 7 0.018
establishment of organelle localization GO:0051656 45 0.018
endocardial cushion morphogenesis GO:0003203 3 0.018
regulation of mesenchymal cell proliferation GO:0010464 1 0.018
heterocycle metabolic process GO:0046483 290 0.018
morphogenesis of an epithelial fold GO:0060571 1 0.018
negative regulation of biological process GO:0048519 304 0.017
anatomical structure homeostasis GO:0060249 36 0.017
Mouse
regulation of skeletal muscle fiber development GO:0048742 2 0.017
limb bud formation GO:0060174 2 0.017
striated muscle cell development GO:0055002 108 0.017
larval development GO:0002164 2 0.017
neuron projection extension GO:1990138 45 0.017
cell motility GO:0048870 244 0.017
pectoral fin development GO:0033339 50 0.017
Zebrafish
central nervous system segmentation GO:0035283 6 0.016
myotube differentiation GO:0014902 45 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
regeneration GO:0031099 91 0.016
Zebrafish
single organism cell adhesion GO:0098602 29 0.016
regulation of rna metabolic process GO:0051252 224 0.015
biosynthetic process GO:0009058 294 0.015
neural plate regionalization GO:0060897 10 0.015
cellular response to organic substance GO:0071310 105 0.015
response to growth factor GO:0070848 39 0.015
meiotic nuclear division GO:0007126 4 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
stem cell differentiation GO:0048863 117 0.015
bone mineralization GO:0030282 9 0.015
response to stress GO:0006950 263 0.015
Zebrafish
nuclear division GO:0000280 23 0.015
stem cell proliferation GO:0072089 4 0.015
protein metabolic process GO:0019538 183 0.014
single organism nuclear import GO:1902593 3 0.014
cellular component movement GO:0006928 335 0.014
nuclear transport GO:0051169 4 0.014
mitochondrion organization GO:0007005 4 0.014
adult behavior GO:0030534 2 0.014
er nucleus signaling pathway GO:0006984 2 0.014
organic acid metabolic process GO:0006082 31 0.014
embryonic hemopoiesis GO:0035162 53 0.014
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.014
forebrain generation of neurons GO:0021872 14 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of transcription dna templated GO:0006355 213 0.013
regulation of cell division GO:0051302 12 0.013
collagen fibril organization GO:0030199 1 0.013
Mouse
sensory perception GO:0007600 39 0.013
Mouse
localization of cell GO:0051674 244 0.013
maintenance of location GO:0051235 4 0.013
neuromast development GO:0048884 46 0.013
mesenchymal cell proliferation GO:0010463 1 0.013
cellular component disassembly GO:0022411 1 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
neural plate pattern specification GO:0060896 12 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
cell migration involved in vasculogenesis GO:0035441 1 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
positive regulation of alcohol biosynthetic process GO:1902932 1 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
cellular ion homeostasis GO:0006873 17 0.012
wnt signaling pathway GO:0016055 80 0.012
foregut morphogenesis GO:0007440 4 0.012
specification of organ identity GO:0010092 2 0.012
locomotory behavior GO:0007626 34 0.012
regulation of ion homeostasis GO:2000021 7 0.012
neuron fate commitment GO:0048663 26 0.011
extracellular matrix organization GO:0030198 27 0.011
Mouse
positive regulation of embryonic development GO:0040019 3 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of cell size GO:0008361 29 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.011
signal transduction GO:0007165 455 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
female gonad development GO:0008585 4 0.011
regulation of gene expression GO:0010468 265 0.011
blood vessel development GO:0001568 246 0.011
vasculature development GO:0001944 278 0.011
skeletal muscle organ development GO:0060538 78 0.011
system process GO:0003008 185 0.011
Mouse
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.011
angiogenesis GO:0001525 158 0.011
developmental cell growth GO:0048588 52 0.010
mesodermal cell differentiation GO:0048333 21 0.010

col11a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.159
osteochondrodysplasia DOID:2256 0 0.159
bone development disease DOID:0080006 0 0.159
disease of anatomical entity DOID:7 0 0.159
bone disease DOID:0080001 0 0.159
connective tissue disease DOID:65 0 0.159