Danio rerio

18 known processes

col11a2

collagen type XI alpha-2

(Aliases: col11a1)

col11a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
notochord development GO:0030903 54 0.921
Zebrafish
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.915
negative regulation of anterior neural cell fate commitment of the neural plate GO:0022001 1 0.885
mediolateral intercalation GO:0060031 3 0.823
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.787
hepatic duct development GO:0061011 2 0.776
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.766
embryonic organ morphogenesis GO:0048562 274 0.740
chondrocyte development GO:0002063 4 0.641
specification of organ axis polarity GO:0010084 2 0.638
sequestering of calcium ion GO:0051208 3 0.598
skeletal system development GO:0001501 181 0.568
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.566
embryonic organ development GO:0048568 381 0.504
Zebrafish
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.491
optic placode formation GO:0001743 4 0.427
thrombocyte differentiation GO:0002574 4 0.403
sequestering of metal ion GO:0051238 3 0.350
sensory perception of mechanical stimulus GO:0050954 16 0.348
Mouse
optic placode formation involved in camera type eye formation GO:0046619 3 0.327
fin morphogenesis GO:0033334 53 0.325
Zebrafish
anterior head development GO:0097065 2 0.323
regulation of wnt signaling pathway calcium modulating pathway GO:0008591 3 0.304
sensory organ morphogenesis GO:0090596 200 0.299
heart morphogenesis GO:0003007 156 0.298
extracellular structure organization GO:0043062 27 0.279
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.277
chondrocyte differentiation GO:0002062 7 0.276
Mouse
regulation of anterior head development GO:2000742 2 0.267
establishment of protein localization to organelle GO:0072594 4 0.260
embryonic camera type eye formation GO:0060900 10 0.255
cartilage condensation GO:0001502 3 0.243
ion homeostasis GO:0050801 41 0.241
embryo development ending in birth or egg hatching GO:0009792 271 0.238
regulation of sequestering of calcium ion GO:0051282 4 0.234
fin regeneration GO:0031101 51 0.231
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.223
cartilage morphogenesis GO:0060536 13 0.208
inner ear morphogenesis GO:0042472 63 0.203
embryonic skeletal system development GO:0048706 97 0.198
spinal cord anterior posterior patterning GO:0021512 1 0.186
embryonic neurocranium morphogenesis GO:0048702 15 0.185
sensory organ development GO:0007423 393 0.180
hepatocyte proliferation GO:0072574 2 0.175
skeletal system morphogenesis GO:0048705 102 0.165
Mouse
embryonic digestive tract development GO:0048566 4 0.161
proteoglycan metabolic process GO:0006029 14 0.158
developmental growth GO:0048589 166 0.153
Zebrafish
embryonic heart tube morphogenesis GO:0003143 108 0.151
cartilage development GO:0051216 96 0.139
negative regulation of sequestering of calcium ion GO:0051283 4 0.121
negative regulation of cell communication GO:0010648 96 0.121
chordate embryonic development GO:0043009 271 0.117
growth plate cartilage development GO:0003417 2 0.117
cellular response to external stimulus GO:0071496 2 0.116
embryonic digestive tract morphogenesis GO:0048557 3 0.112
negative regulation of signaling GO:0023057 96 0.112
negative regulation of wnt signaling pathway GO:0030178 30 0.110
organelle localization GO:0051640 49 0.108
cell morphogenesis GO:0000902 289 0.107
gastrulation GO:0007369 208 0.107
wound healing GO:0042060 90 0.107
Zebrafish
embryonic skeletal system morphogenesis GO:0048704 93 0.106
calcium ion homeostasis GO:0055074 19 0.105
embryonic heart tube development GO:0035050 133 0.101
endodermal digestive tract morphogenesis GO:0061031 2 0.098
growth plate cartilage morphogenesis GO:0003422 1 0.098
somitogenesis GO:0001756 87 0.097
cation homeostasis GO:0055080 33 0.094
gall bladder development GO:0061010 1 0.093
rostrocaudal neural tube patterning GO:0021903 29 0.089
fin development GO:0033333 77 0.088
Zebrafish
axon extension involved in axon guidance GO:0048846 10 0.088
connective tissue development GO:0061448 99 0.086
protein targeting to nucleus GO:0044744 3 0.086
regulation of cell communication GO:0010646 232 0.086
epithalamus development GO:0021538 10 0.085
heterocycle biosynthetic process GO:0018130 215 0.084
heart looping GO:0001947 94 0.082
release of sequestered calcium ion into cytosol GO:0051209 3 0.080
regulation of signaling GO:0023051 235 0.079
negative regulation of signal transduction GO:0009968 94 0.078
response to radiation GO:0009314 51 0.076
endochondral bone growth GO:0003416 2 0.075
specification of symmetry GO:0009799 204 0.075
specification of axis polarity GO:0065001 4 0.074
fertilization GO:0009566 3 0.072
neural plate development GO:0001840 10 0.071
tissue regeneration GO:0042246 74 0.071
Zebrafish
ear morphogenesis GO:0042471 64 0.069
determination of heart left right asymmetry GO:0061371 117 0.068
morphogenesis of an epithelium GO:0002009 333 0.068
response to external stimulus GO:0009605 264 0.068
Zebrafish
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.066
regulation of cellular response to growth factor stimulus GO:0090287 35 0.064
calcium ion transport into cytosol GO:0060402 3 0.063
protein import GO:0017038 3 0.062
swim bladder development GO:0048794 19 0.062
cell aggregation GO:0098743 3 0.061
appendage development GO:0048736 80 0.061
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.058
regulation of axon extension involved in axon guidance GO:0048841 6 0.057
muscle organ development GO:0007517 101 0.057
regulation of anatomical structure morphogenesis GO:0022603 130 0.057
tissue homeostasis GO:0001894 25 0.057
Mouse
divalent inorganic cation homeostasis GO:0072507 22 0.055
regulation of biomineral tissue development GO:0070167 2 0.054
protein import into nucleus GO:0006606 3 0.054
digestive tract development GO:0048565 265 0.053
establishment of mitotic spindle orientation GO:0000132 10 0.053
positive regulation of fibroblast growth factor receptor signaling pathway GO:0045743 9 0.052
mesodermal cell fate commitment GO:0001710 14 0.050
growth GO:0040007 174 0.049
Zebrafish
ossification GO:0001503 23 0.049
Zebrafish
metal ion homeostasis GO:0055065 26 0.048
otic vesicle morphogenesis GO:0071600 34 0.047
epithelial cell morphogenesis GO:0003382 2 0.046
nuclear import GO:0051170 3 0.046
skeletal muscle tissue development GO:0007519 67 0.046
regulation of biological quality GO:0065008 263 0.046
Mouse
odontogenesis of dentin containing tooth GO:0042475 1 0.045
cellular protein catabolic process GO:0044257 4 0.045
detection of abiotic stimulus GO:0009582 24 0.045
digestive tract morphogenesis GO:0048546 231 0.044
regulation of bone mineralization GO:0030500 2 0.044
neural plate morphogenesis GO:0001839 7 0.044
otic vesicle formation GO:0030916 27 0.044
embryonic cranial skeleton morphogenesis GO:0048701 90 0.044
cytosolic calcium ion transport GO:0060401 3 0.043
regulation of fibroblast growth factor receptor signaling pathway GO:0040036 20 0.042
muscle structure development GO:0061061 196 0.042
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.041
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.041
locomotion GO:0040011 313 0.041
neural tube patterning GO:0021532 33 0.040
axis elongation GO:0003401 31 0.040
response to organic cyclic compound GO:0014070 51 0.039
modification dependent protein catabolic process GO:0019941 3 0.039
response to wounding GO:0009611 116 0.038
Zebrafish
homeostatic process GO:0042592 142 0.038
Mouse
cellular component biogenesis GO:0044085 178 0.037
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.036
regulation of nitrogen compound metabolic process GO:0051171 251 0.036
single organism transport GO:0044765 206 0.036
cranial suture morphogenesis GO:0060363 1 0.036
embryonic skeletal joint development GO:0072498 3 0.036
cell migration involved in gastrulation GO:0042074 79 0.035
somite development GO:0061053 96 0.035
determination of bilateral symmetry GO:0009855 204 0.034
dorsal ventral neural tube patterning GO:0021904 1 0.034
heart development GO:0007507 313 0.033
cell morphogenesis involved in differentiation GO:0000904 195 0.033
nucleoside monophosphate catabolic process GO:0009125 4 0.033
phosphorus metabolic process GO:0006793 109 0.032
regulation of developmental growth GO:0048638 38 0.032
ubiquitin dependent protein catabolic process GO:0006511 3 0.032
sensory system development GO:0048880 76 0.032
cellular component morphogenesis GO:0032989 336 0.032
fibroblast growth factor receptor signaling pathway GO:0008543 22 0.030
formation of primary germ layer GO:0001704 62 0.030
intracellular transport GO:0046907 32 0.030
basement membrane assembly GO:0070831 3 0.029
cellular component assembly GO:0022607 170 0.029
dorsal convergence GO:0060030 14 0.028
lateral line system development GO:0048925 76 0.028
cellular homeostasis GO:0019725 26 0.028
response to alkaloid GO:0043279 2 0.028
vestibular receptor cell differentiation GO:0060114 3 0.028
protein localization to nucleus GO:0034504 3 0.028
cellular metal ion homeostasis GO:0006875 16 0.028
biomineral tissue development GO:0031214 13 0.028
regulation of protein targeting GO:1903533 2 0.028
single organismal cell cell adhesion GO:0016337 29 0.027
non canonical wnt signaling pathway GO:0035567 13 0.027
ribonucleoside monophosphate catabolic process GO:0009158 4 0.027
bone morphogenesis GO:0060349 11 0.026
regulation of cellular metabolic process GO:0031323 320 0.026
organic substance biosynthetic process GO:1901576 289 0.026
regulation of jun kinase activity GO:0043506 3 0.026
transport GO:0006810 220 0.026
positive regulation of cellular catabolic process GO:0031331 3 0.026
cellular macromolecule metabolic process GO:0044260 391 0.025
cell division GO:0051301 20 0.025
nucleocytoplasmic transport GO:0006913 4 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.025
embryonic skeletal joint morphogenesis GO:0060272 3 0.025
regulation of mitotic cell cycle GO:0007346 25 0.025
purine nucleoside monophosphate catabolic process GO:0009128 4 0.025
endoderm development GO:0007492 49 0.025
chemical homeostasis GO:0048878 49 0.025
bmp signaling pathway GO:0030509 52 0.025
cell growth GO:0016049 57 0.025
aging GO:0007568 2 0.024
response to fibroblast growth factor GO:0071774 22 0.024
cellular divalent inorganic cation homeostasis GO:0072503 13 0.024
cellular response to organic cyclic compound GO:0071407 38 0.024
negative regulation of response to stimulus GO:0048585 104 0.024
cell death GO:0008219 121 0.023
regulation of protein catabolic process GO:0042176 1 0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 22 0.023
lateral line development GO:0048882 66 0.022
tube morphogenesis GO:0035239 349 0.022
regulation of calcium ion transport GO:0051924 2 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.022
negative regulation of protein phosphorylation GO:0001933 4 0.022
gastrulation with mouth forming second GO:0001702 44 0.021
inner ear development GO:0048839 126 0.021
regulation of tube size GO:0035150 2 0.021
habenula development GO:0021986 9 0.021
negative regulation of cellular process GO:0048523 283 0.020
cellular aromatic compound metabolic process GO:0006725 295 0.020
cellular cation homeostasis GO:0030003 17 0.020
embryonic limb morphogenesis GO:0030326 2 0.019
positive regulation of catabolic process GO:0009896 4 0.019
unidimensional cell growth GO:0009826 5 0.019
cell migration GO:0016477 237 0.019
negative regulation of canonical wnt signaling pathway GO:0090090 21 0.019
cellular localization GO:0051641 97 0.019
appendage morphogenesis GO:0035107 56 0.019
Zebrafish
negative regulation of mitosis GO:0045839 3 0.018
regulation of non canonical wnt signaling pathway GO:2000050 7 0.018
establishment of organelle localization GO:0051656 45 0.018
endocardial cushion morphogenesis GO:0003203 3 0.018
regulation of mesenchymal cell proliferation GO:0010464 1 0.018
heterocycle metabolic process GO:0046483 290 0.018
morphogenesis of an epithelial fold GO:0060571 1 0.018
negative regulation of biological process GO:0048519 304 0.017
anatomical structure homeostasis GO:0060249 36 0.017
Mouse
regulation of skeletal muscle fiber development GO:0048742 2 0.017
limb bud formation GO:0060174 2 0.017
striated muscle cell development GO:0055002 108 0.017
larval development GO:0002164 2 0.017
neuron projection extension GO:1990138 45 0.017
cell motility GO:0048870 244 0.017
pectoral fin development GO:0033339 50 0.017
Zebrafish
central nervous system segmentation GO:0035283 6 0.016
myotube differentiation GO:0014902 45 0.016
enzyme linked receptor protein signaling pathway GO:0007167 106 0.016
regeneration GO:0031099 91 0.016
Zebrafish
single organism cell adhesion GO:0098602 29 0.016
regulation of rna metabolic process GO:0051252 224 0.015
biosynthetic process GO:0009058 294 0.015
neural plate regionalization GO:0060897 10 0.015
cellular response to organic substance GO:0071310 105 0.015
response to growth factor GO:0070848 39 0.015
meiotic nuclear division GO:0007126 4 0.015
regulation of skeletal muscle tissue development GO:0048641 4 0.015
stem cell differentiation GO:0048863 117 0.015
bone mineralization GO:0030282 9 0.015
response to stress GO:0006950 263 0.015
Zebrafish
nuclear division GO:0000280 23 0.015
stem cell proliferation GO:0072089 4 0.015
protein metabolic process GO:0019538 183 0.014
single organism nuclear import GO:1902593 3 0.014
cellular component movement GO:0006928 335 0.014
nuclear transport GO:0051169 4 0.014
mitochondrion organization GO:0007005 4 0.014
adult behavior GO:0030534 2 0.014
er nucleus signaling pathway GO:0006984 2 0.014
organic acid metabolic process GO:0006082 31 0.014
embryonic hemopoiesis GO:0035162 53 0.014
wnt signaling pathway involved in dorsal ventral axis specification GO:0044332 5 0.014
forebrain generation of neurons GO:0021872 14 0.013
regulation of biosynthetic process GO:0009889 250 0.013
regulation of transcription dna templated GO:0006355 213 0.013
regulation of cell division GO:0051302 12 0.013
collagen fibril organization GO:0030199 1 0.013
Mouse
sensory perception GO:0007600 39 0.013
Mouse
localization of cell GO:0051674 244 0.013
maintenance of location GO:0051235 4 0.013
neuromast development GO:0048884 46 0.013
mesenchymal cell proliferation GO:0010463 1 0.013
cellular component disassembly GO:0022411 1 0.013
dorsal ventral pattern formation GO:0009953 125 0.013
neural plate pattern specification GO:0060896 12 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
cell migration involved in vasculogenesis GO:0035441 1 0.012
aromatic compound biosynthetic process GO:0019438 217 0.012
positive regulation of alcohol biosynthetic process GO:1902932 1 0.012
regulation of multicellular organism growth GO:0040014 4 0.012
cellular ion homeostasis GO:0006873 17 0.012
wnt signaling pathway GO:0016055 80 0.012
foregut morphogenesis GO:0007440 4 0.012
specification of organ identity GO:0010092 2 0.012
locomotory behavior GO:0007626 34 0.012
regulation of ion homeostasis GO:2000021 7 0.012
neuron fate commitment GO:0048663 26 0.011
extracellular matrix organization GO:0030198 27 0.011
Mouse
positive regulation of embryonic development GO:0040019 3 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.011
regulation of cell size GO:0008361 29 0.011
regulation of macromolecule metabolic process GO:0060255 317 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.011
signal transduction GO:0007165 455 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
female gonad development GO:0008585 4 0.011
regulation of gene expression GO:0010468 265 0.011
blood vessel development GO:0001568 246 0.011
vasculature development GO:0001944 278 0.011
skeletal muscle organ development GO:0060538 78 0.011
system process GO:0003008 185 0.011
Mouse
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 5 0.011
angiogenesis GO:0001525 158 0.011
developmental cell growth GO:0048588 52 0.010
mesodermal cell differentiation GO:0048333 21 0.010

col11a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
osteochondrodysplasia DOID:2256 0 0.159
bone development disease DOID:0080006 0 0.159
bone disease DOID:0080001 0 0.159
disease of anatomical entity DOID:7 0 0.159
musculoskeletal system disease DOID:17 0 0.159
connective tissue disease DOID:65 0 0.159