IMP

Process View

Danio rerio

17 genes annotated in zebrafish

Multi-species View

cellular ion homeostasis

GO:0006873

Any process involved in the maintenance of an internal steady state of ions at the level of a cell.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular ion homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular ion homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.675	Rat
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.481
opn4l	opsin 4, like	0.245
epas1b	endothelial PAS domain protein 1b	0.216
calb2b	calbindin 2b, (calretinin)	0.167	Rat
wnt10a	wingless-type MMTV integration site family, member 10a	0.137	Zebrafish
lama2	laminin, alpha 2	0.133
ca2	carbonic anhydrase II	0.125	Mouse
dag1	dystroglycan 1	0.113
atp1a3a	ATPase, Na+/K+ transporting, alpha 3a polypeptide	0.101	Zebrafish
atp2b2	ATPase, Ca++ transporting, plasma membrane 2	0.098
spry4	sprouty (Drosophila) homolog 4	0.091
bcl2	B-cell leukemia/lymphoma 2	0.089	Human Mouse
actn3a	actinin alpha 3a	0.088
ldb3b	LIM domain binding 3b	0.088
hbaa1	hemoglobin alpha adult-1	0.079
mef2ca	myocyte enhancer factor 2ca	0.076
cdh23	cadherin-like 23	0.073	Human
opn1sw2	opsin 1 (cone pigments), short-wave-sensitive 2	0.071	Zebrafish
pkd2	polycystic kidney disease 2	0.071	Human Mouse
hk1	hexokinase 1	0.067
six1b	sine oculis homeobox homolog 1b	0.063
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.062	Human Zebrafish
smyhc1l	slow myosin heavy chain 1, like	0.061
tp73	tumor protein p73	0.060
ret1	receptor tyrosine kinase	0.060
trpc1	transient receptor potential cation channel, subfamily C, member 1	0.058	Human Fly
tbx2a	T-box gene 2a	0.058
drd2b	dopamine receptor D2b	0.056	Human Rat
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.056
clptm1	cleft lip and palate associated transmembrane protein 1	0.055
wnt11r	wingless-type MMTV integration site family, member 11, related	0.055	Zebrafish
atp6v1al	ATPase, H+ transporting, lysosomal V1 subunit A, like	0.054
tnnt2a	troponin T2a, cardiac	0.050	Fly
gngt1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.048
calm1a	calmodulin 1a	0.048	Human
ppargc1al	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like	0.048
plp1b	proteolipid protein 1b	0.047
dbh	dopamine beta hydroxylase	0.046
chat	choline acetyltransferase	0.046
alas2	aminolevulinate, delta-, synthetase 2	0.044	Mouse
opn4x1	opsin 4x1	0.044	Zebrafish
aco1	aconitase 1, soluble	0.043	Mouse
sncgb	synuclein, gamma b (breast cancer-specific protein 1)	0.041
cyp3c1	cytochrome P450, family 3, subfamily c, polypeptide 1	0.041
tnni2a.4	troponin I, skeletal, fast 2a.4	0.040
myl7	myosin, light polypeptide 7, regulatory	0.039
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.039
nbl1	neuroblastoma, suppression of tumorigenicity 1	0.039
pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	0.037
unc45b	unc-45 homolog B (C. elegans)	0.037
opn1lw1	opsin 1 (cone pigments), long-wave-sensitive, 1	0.037	Zebrafish
cyp19a1a	cytochrome P450, family 19, subfamily A, polypeptide 1a	0.037
ca15a	carbonic anhydrase XV a	0.036
or107-1	odorant receptor, family D, subfamily 107, member 1	0.036
mc4r	melanocortin 4 receptor	0.036
ckbb	creatine kinase, brain b	0.035
mapk1	mitogen-activated protein kinase 1	0.035
rag1	recombination activating gene 1	0.034
urod	uroporphyrinogen decarboxylase	0.034
tbx1	T-box 1	0.032
stc1l	stanniocalcin 1, like	0.032
nr2f6a	nuclear receptor subfamily 2, group F, member 6a	0.032
otx5	orthodenticle homolog 5	0.032
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.032	Zebrafish
ctsf	cathepsin F	0.031
opn1sw1	opsin 1 (cone pigments), short-wave-sensitive 1	0.031	Zebrafish
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.031
dusp6	dual specificity phosphatase 6	0.030
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.030
gad2	glutamate decarboxylase 2	0.030
oprd1a	opioid receptor, delta 1a	0.030
grin1a	glutamate receptor, ionotropic, N-methyl D-aspartate 1a	0.029
sb:cb81	sb:cb81	0.029
nadl1.1	neural adhesion molecule L1.1	0.029
matn1	matrilin 1	0.029
galcb	galactosylceramidase b	0.028
stau1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.028
rbm24a	RNA binding motif protein 24a	0.027
calb2a	calbindin 2a	0.027	Rat
wt1b	wilms tumor 1b	0.027
pcsk5b	proprotein convertase subtilisin/kexin type 5b	0.027
wnt3	wingless-type MMTV integration site family, member 3	0.027	Zebrafish
pou4f1	POU domain, class 4, transcription factor 1	0.027
tgm2b	transglutaminase 2b	0.027
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.026
calm1b	calmodulin 1b	0.026
gnb3b	guanine nucleotide binding protein (G protein), beta polypeptide 3b	0.026
lpar1	lysophosphatidic acid receptor 1	0.026	Rat
spag1	sperm associated antigen 1	0.025
esrra	estrogen-related receptor alpha	0.025
atp1a3b	ATPase, Na+/K+ transporting, alpha 3b polypeptide	0.025	Zebrafish
inhbaa	inhibin, beta Aa	0.024
fktn	fukutin	0.024
slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.024
or102-1	odorant receptor, family C, subfamily 102, member 1	0.024
satb2	SATB homeobox 2	0.023
nadl1.2	neural adhesion molecule L1.2	0.023
oxtl	oxytocin-like	0.023	Rat
grna	granulin a	0.023
ahcyl2	S-adenosylhomocysteine hydrolase-like 2	0.023
mtdha	metadherin a	0.022
tnnt3a	troponin T3a, skeletal, fast	0.022	Fly
pitx3	paired-like homeodomain transcription factor 3	0.022
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.022	Human Zebrafish
prrc1	proline-rich coiled-coil 1	0.022
ef1a	elongation factor 1-alpha	0.022
atp2b1a	ATPase, Ca++ transporting, plasma membrane 1a	0.022	Worm
icn	ictacalcin	0.022
opn1mw2	opsin 1 (cone pigments), medium-wave-sensitive, 2	0.021
zgc:63947	zgc:63947	0.021
stac3	SH3 and cysteine rich domain 3	0.021
vmhc	ventricular myosin heavy chain	0.021
zgc:66097	zgc:66097	0.021
ppp4cb	protein phosphatase 4 (formerly X), catalytic subunit b	0.021
wnt9b	wingless-type MMTV integration site family, member 9B	0.021	Zebrafish
hmx2	H6 family homeobox 2	0.021
gna13b	guanine nucleotide binding protein (G protein), alpha 13b	0.021
ryr3	ryanodine receptor 3	0.021
zgc:112359	zgc:112359	0.021
arf1	ADP-ribosylation factor 1	0.020	Human
dlg2	discs, large (Drosophila) homolog 2	0.020
appa	amyloid beta (A4) precursor protein a	0.020	Mouse
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.020
grhl1	grainyhead-like 1 (Drosophila)	0.020
atp2a2a	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a	0.020	Human Zebrafish Mouse Worm Fly
tpma	alpha-tropomyosin	0.019
cmlc1	cardiac myosin light chain-1	0.019
itgb1a	integrin, beta 1a	0.019
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.019
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.019
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.019
hcrt	hypocretin (orexin) neuropeptide precursor	0.019	Rat
veph	ventricular zone expressed PH domain protein	0.019
pdlim3b	PDZ and LIM domain 3b	0.019
foxn4	forkhead box N4	0.019
dclk2	doublecortin-like kinase 2	0.019
ucp3	uncoupling protein 3	0.019
pink1	PTEN induced putative kinase 1	0.019
si:dkey-273o13.1	si:dkey-273o13.1	0.018
zgc:101724	zgc:101724	0.018
scn1lab	sodium channel, voltage-gated, type I like, alpha b	0.018
wnt10b	wingless-type MMTV integration site family, member 10b	0.018	Zebrafish
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.018
lin7a	lin-7 homolog A (C. elegans)	0.018
LOC557062	hypothetical protein LOC557062	0.018
igf1ra	insulin-like growth factor 1a receptor	0.018
mc1r	melanocortin 1 receptor	0.018
nt5e	5'-nucleotidase, ecto (CD73)	0.018
zbtb10	zinc finger and BTB domain containing 10	0.018
glra1	glycine receptor, alpha 1	0.018
cntn1a	contactin 1a	0.017
zbtb4	zinc finger and BTB domain containing 4	0.017
vamp1	vesicle-associated membrane protein 1	0.017
gcm2	glial cells missing homolog 2 (Drosophila)	0.017
kdm5bb	lysine (K)-specific demethylase 5Bb	0.017
si:ch73-60e21.1	si:ch73-60e21.1	0.017
abcc5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	0.017
tnnt3b	troponin T3b, skeletal, fast	0.017	Fly
LOC100150090	sphingosine kinase 2-like	0.017
chrm2a	cholinergic receptor, muscarinic 2a	0.017
exorh	extra-ocular rhodopsin	0.017
mapk7	mitogen-activated protein kinase 7	0.017
dlx4a	distal-less homeobox gene 4a	0.017
pcdh15a	protocadherin 15a	0.016
ca8	carbonic anhydrase VIII	0.016
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.016
alcama	activated leukocyte cell adhesion molecule a	0.016
nrg1	neuregulin 1	0.016
zgc:73336	zgc:73336	0.016
wnt11	wingless-type MMTV integration site family, member 11	0.016	Zebrafish
slc26a4	solute carrier family 26, member 4	0.016
gng7	guanine nucleotide binding protein (G protein), gamma 7	0.016
zgc:56548	zgc:56548	0.016
fbp1b	fructose-1,6-bisphosphatase 1b	0.016
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.016	Zebrafish
nr5a1b	nuclear receptor subfamily 5, group A, member 1b	0.016
opn1mw1	opsin 1 (cone pigments), medium-wave-sensitive, 1	0.016	Zebrafish
cx36.7	connexin 36.7	0.015
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.015
mapk12	mitogen-activated protein kinase 12	0.015
tyr	tyrosinase	0.015
ctnnb1	catenin (cadherin-associated protein), beta 1	0.015
fzd10	frizzled homolog 10	0.015
cpox	coproporphyrinogen oxidase	0.015
polr2b	polymerase (RNA) II (DNA directed) polypeptide B	0.015
paqr8	progestin and adipoQ receptor family member VIII	0.015
ppp3cb	protein phosphatase 3, catalytic subunit, beta isozyme	0.015	Yeast
tbx18	T-box 18	0.015
copa	coatomer protein complex, subunit alpha	0.015
kitb	kit receptor b	0.015
csnk1da	casein kinase 1, delta a	0.015
zgc:193613	zgc:193613	0.015
adcyap1a	adenylate cyclase activating polypeptide 1a	0.014
slc9a3.2	solute carrier family 9 (sodium/hydrogen exchanger), member 3.2	0.014	Worm
bmp7a	bone morphogenetic protein 7a	0.014
gnat1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	0.014
ireb2	iron-responsive element binding protein 2	0.014	Mouse
ahcyl1	S-adenosylhomocysteine hydrolase-like 1	0.014
flncb	filamin C, gamma b (actin binding protein 280)	0.014
large	like-glycosyltransferase	0.014
crfa31.2	IL-4RA-like protein 2	0.014
gpr126	G protein-coupled receptor 126	0.014
scn12aa	sodium channel, voltage gated, type XII, alpha a	0.014
ppdpfa	pancreatic progenitor cell differentiation and proliferation factor a	0.013
adipor1a	adiponectin receptor 1a	0.013
adra2a	adrenergic, alpha-2A-, receptor	0.013
cldn2	claudin 2	0.013
zgc:65851	zgc:65851	0.013
flj13639	flj13639	0.013
snai1a	snail homolog 1a (Drosophila)	0.013
osr2	odd-skipped related 2 (Drosophila)	0.013
zgc:77752	zgc:77752	0.013
twist1a	twist1a	0.013
jak1	Janus kinase 1	0.013
spock3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	0.013
rho	rhodopsin	0.013	Zebrafish
sid4	secreted immunoglobulin domain 4	0.013
odc1	ornithine decarboxylase 1	0.013
rxrbb	retinoid x receptor, beta b	0.013
pvalb4	parvalbumin 4	0.013
mchr1a	melanin-concentrating hormone receptor 1a	0.013
ttna	titin a	0.013
gnat2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.013
nkx2.5	NK2 transcription factor related 5	0.013
pvalb8	parvalbumin 8	0.013	Rat
atp1b2b	ATPase, Na+/K+ transporting, beta 2b polypeptide	0.013
snap25b	synaptosome-associated protein 25b	0.013
glra4b	glycine receptor, alpha 4b	0.013
scinla	scinderin like a	0.013
opn4a	opsin 4a (melanopsin)	0.013	Zebrafish
lrrc33	leucine rich repeat containing 33	0.013
neb	nebulin	0.013
pth1a	parathyroid hormone 1a	0.013
tgfb3	transforming growth factor, beta 3	0.013
esrrga	estrogen-related receptor gamma a	0.013
camsap1l1	calmodulin regulated spectrin-associated protein 1-like 1	0.013
srl	sarcalumenin	0.013
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.013
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.013
coro1a	coronin, actin binding protein, 1A	0.012	Mouse
atp6v0ca	ATPase, H+ transporting, lysosomal, V0 subunit c, a	0.012
lzts2a	leucine zipper, putative tumor suppressor 2a	0.012
psen1	presenilin 1	0.012	Human Mouse
anxa13	annexin A13	0.012
nkx3.2	NK3 homeobox 2	0.012
col11a2	collagen type XI alpha-2	0.012
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.012	Human Zebrafish
has3	hyaluronan synthase 3	0.012
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.012
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.012
hoxa13b	homeo box A13b	0.012
snx4	sorting nexin 4	0.012
eno2	enolase 2	0.012
zgc:56376	zgc:56376	0.012
wls	wntless homolog (Drosophila)	0.012
nccrp1	nonspecific cytotoxic cell receptor protein 1	0.012
rc3	rabconnectin 3	0.012
tfr1a	transferrin receptor 1a	0.012
foxo3a	forkhead box O3A	0.012
atp6v1h	ATPase, H+ transporting, lysosomal, V1 subunit H	0.012
tnnc1a	troponin C type 1a (slow)	0.012
tmem2	transmembrane protein 2	0.012
avpr1b	arginine vasopressin receptor 1B	0.011
ldb3a	LIM-domain binding factor 3a	0.011
si:ch73-9j13.1	si:ch73-9j13.1	0.011
slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.011	Human Mouse
gclm	glutamate-cysteine ligase, modifier subunit	0.011
atp6v1g1	ATPase, H+ transporting, V1 subunit G isoform 1	0.011
ugdh	UDP-glucose dehydrogenase	0.011
wnt4a	wingless-type MMTV integration site family, member 4a	0.011	Zebrafish
ip6k2	inositol hexaphosphate kinase 2	0.011
itgb1b.1	integrin, beta 1b.1	0.011
trpm2	transient receptor potential cation channel, subfamily M, member 2	0.011
zgc:103652	zgc:103652	0.011
nog3	noggin 3	0.011
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.011
zgc:86757	zgc:86757	0.011
tfa	transferrin-a	0.011
cga	glycoprotein hormones, alpha polypeptide	0.011
ihhb	Indian hedgehog homolog b	0.011
lamb4	laminin, beta 4	0.011
efna1b	ephrin A1b	0.011
men1	multiple endocrine neoplasia type 1 and multiple endocrine neoplasia I	0.011
spon1a	spondin 1a	0.011
slc25a4	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	0.011	Fly
atp1a1a.5	ATPase, Na+/K+ transporting, alpha 1a.5 polypeptide	0.011	Human Zebrafish
lect1	leukocyte cell derived chemotaxin 1	0.011
or111-7	odorant receptor, family D, subfamily 111, member 7	0.011
atp2a1l	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like	0.011	Zebrafish Worm Fly
smyhc1	slow myosin heavy chain 1	0.011
lamb2	laminin, beta 2 (laminin S)	0.011
cltca	clathrin, heavy polypeptide a (Hc)	0.011
cdkrap3	CDK5 regulatory subunit associated protein 3	0.011
als2cr4a	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4a	0.011
sox4a	SRY-box containing gene 4a	0.011
csad	cysteine sulfinic acid decarboxylase	0.011
mapk14a	mitogen-activated protein kinase 14a	0.011	Yeast
mmp15a	matrix metallopeptidase 15a	0.011
fbn2b	fibrillin 2b	0.010
zgc:162270	zgc:162270	0.010
mych	myelocytomatosis oncogene homolog	0.010
zgc:171802	zgc:171802	0.010
si:dkey-12o15.1	si:dkey-12o15.1	0.010
esrrd	estrogen-related receptor delta	0.010
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.010
slc6a4a	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4A	0.010
musk	muscle, skeletal, receptor tyrosine kinase	0.010
trpa1a	transient receptor potential cation channel, subfamily A, member 1a	0.010
actn2	actinin, alpha 2	0.010
sp2	sp2 transcription factor	0.010
wu:fj62d01	wu:fj62d01	0.010
LOC100004946	transient receptor potential cation channel subfamily M member 4-like	0.010
fam3c	family with sequence similarity 3, member C	0.010
sb:cb1058	sb:cb1058	0.010
fundc1	FUN14 domain containing 1	0.010
si:ch211-142k18.1	si:ch211-142k18.1	0.010
zgc:73142	zgc:73142	0.010
LOC100006361	galanin-like	0.010