Danio rerio

19 known processes

drl

draculin

(Aliases: dra,cb253,zgc:109857)

drl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 349 0.846
macromolecule biosynthetic process GO:0009059 227 0.785
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.770
heart jogging GO:0003146 40 0.730
embryonic hemopoiesis GO:0035162 53 0.601
erythrocyte maturation GO:0043249 8 0.594
determination of heart left right asymmetry GO:0061371 117 0.579
myeloid cell development GO:0061515 32 0.571
nucleobase containing compound biosynthetic process GO:0034654 205 0.535
erythrocyte homeostasis GO:0034101 55 0.516
regulation of primary metabolic process GO:0080090 311 0.515
organic substance biosynthetic process GO:1901576 289 0.504
cardiac chamber formation GO:0003207 4 0.479
transcription dna templated GO:0006351 181 0.477
regulation of rna biosynthetic process GO:2001141 213 0.477
cellular aromatic compound metabolic process GO:0006725 295 0.474
erythrocyte differentiation GO:0030218 54 0.460
cell surface receptor signaling pathway GO:0007166 325 0.459
bmp signaling pathway GO:0030509 52 0.454
aromatic compound biosynthetic process GO:0019438 217 0.451
nucleic acid metabolic process GO:0090304 244 0.449
erythrocyte development GO:0048821 24 0.431
heart morphogenesis GO:0003007 156 0.416
cellular macromolecule biosynthetic process GO:0034645 224 0.413
digestive tract development GO:0048565 265 0.411
determination of left right symmetry GO:0007368 179 0.410
regulation of cellular biosynthetic process GO:0031326 245 0.401
cellular macromolecule metabolic process GO:0044260 391 0.392
determination of bilateral symmetry GO:0009855 204 0.381
hematopoietic or lymphoid organ development GO:0048534 191 0.379
regulation of cellular metabolic process GO:0031323 320 0.372
embryonic heart tube morphogenesis GO:0003143 108 0.346
transcription from rna polymerase ii promoter GO:0006366 80 0.345
cellular nitrogen compound biosynthetic process GO:0044271 218 0.338
cell migration involved in gastrulation GO:0042074 79 0.334
regulation of macromolecule biosynthetic process GO:0010556 225 0.329
heart valve formation GO:0003188 4 0.328
regulation of rna metabolic process GO:0051252 224 0.324
megakaryocyte differentiation GO:0030219 1 0.314
biosynthetic process GO:0009058 294 0.304
convergent extension GO:0060026 118 0.287
myeloid leukocyte differentiation GO:0002573 15 0.285
cellular biosynthetic process GO:0044249 286 0.283
regulation of gene expression GO:0010468 265 0.278
response to external biotic stimulus GO:0043207 97 0.268
specification of symmetry GO:0009799 204 0.266
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.266
atrioventricular valve formation GO:0003190 3 0.265
immune response GO:0006955 28 0.264
cellular nitrogen compound metabolic process GO:0034641 290 0.261
regulation of nodal signaling pathway GO:1900107 4 0.255
heterocycle biosynthetic process GO:0018130 215 0.252
regulation of cell differentiation GO:0045595 142 0.248
organic cyclic compound metabolic process GO:1901360 301 0.242
regulation of nucleic acid templated transcription GO:1903506 213 0.241
rna biosynthetic process GO:0032774 181 0.239
negative regulation of leukocyte differentiation GO:1902106 1 0.236
dna methylation or demethylation GO:0044728 8 0.233
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.233
regulation of myeloid leukocyte differentiation GO:0002761 5 0.221
regulation of erythrocyte differentiation GO:0045646 2 0.219
regulation of cardiac muscle tissue development GO:0055024 1 0.213
heart looping GO:0001947 94 0.210
liver development GO:0001889 96 0.203
heart field specification GO:0003128 1 0.195
regulation of ectodermal cell fate specification GO:0042665 2 0.192
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.181
atrial ventricular junction remodeling GO:0003294 2 0.178
granulocyte differentiation GO:0030851 8 0.172
muscle structure development GO:0061061 196 0.171
nerve development GO:0021675 45 0.171
regulation of bmp signaling pathway GO:0030510 39 0.167
striated muscle cell differentiation GO:0051146 129 0.165
organic cyclic compound biosynthetic process GO:1901362 223 0.163
regulation of multicellular organismal process GO:0051239 277 0.160
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.158
immune system development GO:0002520 191 0.155
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.154
cilium movement involved in cell motility GO:0060294 3 0.145
immune system process GO:0002376 241 0.144
rna metabolic process GO:0016070 219 0.142
death GO:0016265 121 0.141
positive regulation of nucleic acid templated transcription GO:1903508 57 0.135
embryonic heart tube development GO:0035050 133 0.128
positive regulation of gene expression GO:0010628 71 0.127
positive regulation of biological process GO:0048518 253 0.122
pancreas development GO:0031016 84 0.121
transition metal ion transport GO:0000041 6 0.121
response to lipid GO:0033993 60 0.120
enzyme linked receptor protein signaling pathway GO:0007167 106 0.120
heart contraction GO:0060047 71 0.116
immune effector process GO:0002252 23 0.114
homeostasis of number of cells GO:0048872 62 0.113
iron ion transport GO:0006826 4 0.113
regulation of metabolic process GO:0019222 359 0.112
macrophage differentiation GO:0030225 7 0.112
myeloid cell homeostasis GO:0002262 56 0.109
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.109
cardiac muscle tissue development GO:0048738 48 0.109
hepaticobiliary system development GO:0061008 98 0.108
embryonic organ development GO:0048568 381 0.107
regulation of developmental process GO:0050793 247 0.106
heterocycle metabolic process GO:0046483 290 0.106
collagen metabolic process GO:0032963 2 0.101
female gonad development GO:0008585 4 0.099
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.098
larval development GO:0002164 2 0.098
nucleobase containing compound metabolic process GO:0006139 274 0.095
myeloid cell differentiation GO:0030099 86 0.094
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.093
gene expression GO:0010467 252 0.089
monocyte differentiation GO:0030224 2 0.088
primitive hemopoiesis GO:0060215 27 0.086
nucleic acid templated transcription GO:0097659 181 0.083
regulation of immune system process GO:0002682 34 0.083
negative regulation of mesodermal cell fate specification GO:0042662 3 0.083
septum transversum development GO:0003343 4 0.083
hematopoietic progenitor cell differentiation GO:0002244 23 0.082
negative regulation of granulocyte differentiation GO:0030853 1 0.081
positive regulation of rna metabolic process GO:0051254 59 0.079
regulation of neutrophil differentiation GO:0045658 3 0.077
epithelial tube morphogenesis GO:0060562 148 0.077
regulation of multicellular organismal development GO:2000026 223 0.076
morphogenesis of an epithelium GO:0002009 333 0.074
signal transduction GO:0007165 455 0.074
ectodermal cell fate specification GO:0001715 2 0.074
regulation of myeloid cell differentiation GO:0045637 8 0.073
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.072
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.071
regulation of reproductive process GO:2000241 4 0.070
regulation of transcription dna templated GO:0006355 213 0.070
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.068
protein metabolic process GO:0019538 183 0.067
cell migration to the midline involved in heart development GO:0003318 12 0.067
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.067
negative regulation of cellular biosynthetic process GO:0031327 55 0.067
platelet formation GO:0030220 1 0.066
negative regulation of gene expression GO:0010629 65 0.065
regulation of ectoderm development GO:2000383 2 0.065
positive regulation of transcription dna templated GO:0045893 57 0.065
determination of left right asymmetry in diencephalon GO:0035462 4 0.064
regulation of cell communication GO:0010646 232 0.062
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.062
negative regulation of myeloid cell differentiation GO:0045638 1 0.062
ectodermal cell fate commitment GO:0001712 2 0.062
regulation of protein complex assembly GO:0043254 3 0.061
hematopoietic stem cell migration GO:0035701 4 0.061
positive regulation of macromolecule metabolic process GO:0010604 93 0.058
cardiogenic plate morphogenesis GO:0003142 1 0.058
optic placode formation involved in camera type eye formation GO:0046619 3 0.057
regulation of biosynthetic process GO:0009889 250 0.057
atrioventricular valve development GO:0003171 11 0.055
negative regulation of multicellular organismal process GO:0051241 69 0.054
multicellular organismal metabolic process GO:0044236 2 0.053
posterior lateral line development GO:0048916 38 0.053
regulation of cell activation GO:0050865 1 0.053
embryonic heart tube left right pattern formation GO:0060971 5 0.053
heart valve development GO:0003170 14 0.052
nuclear transport GO:0051169 4 0.052
atrioventricular valve morphogenesis GO:0003181 6 0.051
negative regulation of chromosome organization GO:2001251 1 0.051
muscle cell differentiation GO:0042692 139 0.050
regulation of macromolecule metabolic process GO:0060255 317 0.050
cellular protein metabolic process GO:0044267 129 0.050
ectodermal cell differentiation GO:0010668 2 0.049
gastrulation with mouth forming second GO:0001702 44 0.049
response to stress GO:0006950 263 0.049
astrocyte differentiation GO:0048708 1 0.048
cellular protein catabolic process GO:0044257 4 0.047
positive regulation of neuron migration GO:2001224 2 0.047
definitive hemopoiesis GO:0060216 18 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.046
positive regulation of rna biosynthetic process GO:1902680 57 0.046
response to fluid shear stress GO:0034405 2 0.046
response to external stimulus GO:0009605 264 0.045
mesenchyme development GO:0060485 127 0.045
cellular response to stress GO:0033554 62 0.044
regulation of nitrogen compound metabolic process GO:0051171 251 0.044
intermediate mesoderm development GO:0048389 2 0.044
cardiac muscle cell differentiation GO:0055007 30 0.043
sensory organ development GO:0007423 393 0.042
cell proliferation involved in heart morphogenesis GO:0061323 2 0.041
regulation of cell death GO:0010941 103 0.041
response to axon injury GO:0048678 14 0.041
response to biotic stimulus GO:0009607 97 0.040
negative regulation of biological process GO:0048519 304 0.040
determination of left right asymmetry in nervous system GO:0035545 4 0.039
digestive tract morphogenesis GO:0048546 231 0.038
antimicrobial humoral response GO:0019730 2 0.038
regulation of cytokine production GO:0001817 3 0.038
nodal signaling pathway GO:0038092 7 0.038
muscle tissue development GO:0060537 110 0.038
muscle organ development GO:0007517 101 0.037
heart development GO:0007507 313 0.037
cardiac atrium morphogenesis GO:0003209 2 0.036
response to endogenous stimulus GO:0009719 83 0.036
negative regulation of mesoderm development GO:2000381 5 0.036
cell death GO:0008219 121 0.036
heart formation GO:0060914 13 0.034
negative regulation of transcription dna templated GO:0045892 45 0.034
response to chemical GO:0042221 320 0.033
homeostatic process GO:0042592 142 0.033
cardiac ventricle development GO:0003231 9 0.033
digestive system development GO:0055123 289 0.033
regulation of response to stress GO:0080134 36 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.032
positive regulation of myeloid cell differentiation GO:0045639 2 0.032
peptide metabolic process GO:0006518 1 0.031
cellular amide metabolic process GO:0043603 4 0.031
megakaryocyte development GO:0035855 1 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.030
endoderm formation GO:0001706 29 0.030
response to vitamin GO:0033273 3 0.029
protein complex assembly GO:0006461 30 0.029
formation of primary germ layer GO:0001704 62 0.029
dna methylation GO:0006306 8 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
actin filament polymerization GO:0030041 2 0.028
cell migration GO:0016477 237 0.027
neuron development GO:0048666 262 0.027
organism emergence from protective structure GO:0071684 4 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
negative regulation of cell differentiation GO:0045596 46 0.027
fin morphogenesis GO:0033334 53 0.026
response to other organism GO:0051707 97 0.026
canonical wnt signaling pathway GO:0060070 48 0.026
negative regulation of chromatin modification GO:1903309 1 0.025
innate immune response GO:0045087 13 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.025
defense response GO:0006952 47 0.024
ectoderm formation GO:0001705 2 0.024
negative regulation of protein complex assembly GO:0031333 1 0.024
rhombomere 5 development GO:0021571 4 0.024
negative regulation of cell fate commitment GO:0010454 13 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.024
regulation of collateral sprouting in absence of injury GO:0048696 4 0.024
heart valve morphogenesis GO:0003179 8 0.023
positive regulation of jun kinase activity GO:0043507 2 0.023
heart process GO:0003015 71 0.023
cardiac chamber morphogenesis GO:0003206 12 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
generation of neurons GO:0048699 385 0.023
leukocyte differentiation GO:0002521 25 0.022
dorsal aorta morphogenesis GO:0035912 3 0.022
regulation of response to stimulus GO:0048583 269 0.022
aging GO:0007568 2 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regionalization GO:0003002 274 0.021
negative regulation of cellular process GO:0048523 283 0.021
multicellular organismal macromolecule metabolic process GO:0044259 2 0.021
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.021
cardiac ventricle formation GO:0003211 1 0.021
convergent extension involved in organogenesis GO:0060029 10 0.021
cell cell adhesion involved in gastrulation GO:0070586 4 0.021
growth GO:0040007 174 0.020
cell projection organization GO:0030030 284 0.020
inner ear receptor cell fate commitment GO:0060120 4 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.020
mesodermal cell fate specification GO:0007501 12 0.020
positive regulation of dna templated transcription elongation GO:0032786 1 0.020
methylation GO:0032259 22 0.020
cardiac atrium development GO:0003230 4 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
spermatid development GO:0007286 2 0.020
regulation of activin receptor signaling pathway GO:0032925 5 0.020
endodermal cell fate determination GO:0007493 2 0.020
mesoderm development GO:0007498 88 0.019
regulation of heart growth GO:0060420 2 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.019
dorsal aorta development GO:0035907 4 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
positive regulation of cellular process GO:0048522 201 0.019
regulation of signal transduction GO:0009966 225 0.019
cardioblast migration GO:0003260 7 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
cardiac chamber development GO:0003205 19 0.018
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.018
cranial nerve development GO:0021545 42 0.018
locomotion GO:0040011 313 0.018
hemopoiesis GO:0030097 183 0.017
regulation of macrophage differentiation GO:0045649 1 0.017
programmed cell death GO:0012501 119 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
foregut morphogenesis GO:0007440 4 0.017
regulation of nucleotide metabolic process GO:0006140 17 0.017
compound eye development GO:0048749 2 0.017
proteolysis GO:0006508 38 0.017
fin development GO:0033333 77 0.017
regulation of cysteine type endopeptidase activity GO:2000116 21 0.016
immunoglobulin mediated immune response GO:0016064 3 0.016
renal system process involved in regulation of blood volume GO:0001977 1 0.016
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.016
response to oxygen containing compound GO:1901700 55 0.016
regulation of cytokine biosynthetic process GO:0042035 1 0.016
regulation of dna methylation GO:0044030 5 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
positive regulation of protein complex assembly GO:0031334 2 0.015
embryonic foregut morphogenesis GO:0048617 1 0.015
b cell activation GO:0042113 2 0.015
ectodermal placode morphogenesis GO:0071697 32 0.015
regulation of biological quality GO:0065008 263 0.015
response to organic cyclic compound GO:0014070 51 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
mesendoderm development GO:0048382 10 0.015
dna modification GO:0006304 8 0.015
positive regulation of jnk cascade GO:0046330 3 0.015
platelet morphogenesis GO:0036344 1 0.015
cytoskeleton organization GO:0007010 96 0.015
negative regulation of muscle tissue development GO:1901862 2 0.015
mesenchymal cell differentiation GO:0048762 87 0.014
regulation of oocyte development GO:0060281 3 0.014
regulation of mitotic cell cycle GO:0007346 25 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
negative regulation of cytokine production GO:0001818 1 0.014
dna alkylation GO:0006305 8 0.014
maintenance of location GO:0051235 4 0.014
catabolic process GO:0009056 32 0.014
gland development GO:0048732 143 0.014
tissue regeneration GO:0042246 74 0.014
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.014
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.014
regulation of response to external stimulus GO:0032101 31 0.014
artery development GO:0060840 22 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
positive regulation of transport GO:0051050 2 0.014
cardiac conduction system development GO:0003161 1 0.014
mesoderm formation GO:0001707 43 0.013
small molecule metabolic process GO:0044281 77 0.013
positive regulation of catabolic process GO:0009896 4 0.013
organic substance catabolic process GO:1901575 28 0.013
blood circulation GO:0008015 87 0.013
palate development GO:0060021 8 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of bone mineralization GO:0030500 2 0.013
regulation of signaling GO:0023051 235 0.013
gastrulation GO:0007369 208 0.013
response to alcohol GO:0097305 14 0.013
outflow tract morphogenesis GO:0003151 1 0.013
angiogenesis GO:0001525 158 0.013
cytokine metabolic process GO:0042107 1 0.013
angioblast cell migration GO:0035476 9 0.013
regulation of canonical wnt signaling pathway GO:0060828 34 0.013
cell part morphogenesis GO:0032990 246 0.013
somatic stem cell maintenance GO:0035019 1 0.013
brain development GO:0007420 293 0.012
response to organic substance GO:0010033 153 0.012
optic nerve morphogenesis GO:0021631 6 0.012
nitric oxide metabolic process GO:0046209 2 0.012
bmp signaling pathway involved in heart development GO:0061312 15 0.012
cell migration involved in heart development GO:0060973 22 0.012
positive regulation of neural retina development GO:0061075 1 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
regulation of cellular extravasation GO:0002691 1 0.011
response to glucocorticoid GO:0051384 1 0.011
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.011
olfactory bulb development GO:0021772 4 0.011
neutrophil differentiation GO:0030223 6 0.011
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.011
protein acylation GO:0043543 3 0.011
cellular response to starvation GO:0009267 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
regulation of biomineral tissue development GO:0070167 2 0.011
calcium ion homeostasis GO:0055074 19 0.011
positive regulation of cell activation GO:0050867 1 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
amide biosynthetic process GO:0043604 1 0.011
aorta development GO:0035904 4 0.011
glial cell differentiation GO:0010001 42 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
negative regulation of developmental process GO:0051093 65 0.011
spemann organizer formation GO:0060061 10 0.011
positive regulation of developmental process GO:0051094 50 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
growth plate cartilage development GO:0003417 2 0.011
ion transport GO:0006811 114 0.011
response to wounding GO:0009611 116 0.011
wnt signaling pathway involved in heart development GO:0003306 5 0.011
limb bud formation GO:0060174 2 0.011
regulation of cardiac chamber morphogenesis GO:1901219 2 0.011
cellular response to external stimulus GO:0071496 2 0.011
ear morphogenesis GO:0042471 64 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of myelination GO:0031641 1 0.010
positive regulation of neurogenesis GO:0050769 24 0.010
protein k48 linked ubiquitination GO:0070936 1 0.010
negative regulation of histone modification GO:0031057 1 0.010
regulation of heart morphogenesis GO:2000826 17 0.010
pectoral fin development GO:0033339 50 0.010
centrosome cycle GO:0007098 1 0.010
striated muscle tissue development GO:0014706 110 0.010
regulation of cardiac muscle cell differentiation GO:2000725 1 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
morphogenesis of embryonic epithelium GO:0016331 30 0.010

drl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.036
cancer DOID:162 0 0.036