Danio rerio

19 known processes

drl

draculin

(Aliases: dra,cb253,zgc:109857)

drl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tube morphogenesis GO:0035239 349 0.846
macromolecule biosynthetic process GO:0009059 227 0.785
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.770
heart jogging GO:0003146 40 0.730
embryonic hemopoiesis GO:0035162 53 0.601
erythrocyte maturation GO:0043249 8 0.594
determination of heart left right asymmetry GO:0061371 117 0.579
myeloid cell development GO:0061515 32 0.571
nucleobase containing compound biosynthetic process GO:0034654 205 0.535
erythrocyte homeostasis GO:0034101 55 0.516
regulation of primary metabolic process GO:0080090 311 0.515
organic substance biosynthetic process GO:1901576 289 0.504
cardiac chamber formation GO:0003207 4 0.479
transcription dna templated GO:0006351 181 0.477
regulation of rna biosynthetic process GO:2001141 213 0.477
cellular aromatic compound metabolic process GO:0006725 295 0.474
erythrocyte differentiation GO:0030218 54 0.460
cell surface receptor signaling pathway GO:0007166 325 0.459
bmp signaling pathway GO:0030509 52 0.454
aromatic compound biosynthetic process GO:0019438 217 0.451
nucleic acid metabolic process GO:0090304 244 0.449
erythrocyte development GO:0048821 24 0.431
heart morphogenesis GO:0003007 156 0.416
cellular macromolecule biosynthetic process GO:0034645 224 0.413
digestive tract development GO:0048565 265 0.411
determination of left right symmetry GO:0007368 179 0.410
regulation of cellular biosynthetic process GO:0031326 245 0.401
cellular macromolecule metabolic process GO:0044260 391 0.392
determination of bilateral symmetry GO:0009855 204 0.381
hematopoietic or lymphoid organ development GO:0048534 191 0.379
regulation of cellular metabolic process GO:0031323 320 0.372
embryonic heart tube morphogenesis GO:0003143 108 0.346
transcription from rna polymerase ii promoter GO:0006366 80 0.345
cellular nitrogen compound biosynthetic process GO:0044271 218 0.338
cell migration involved in gastrulation GO:0042074 79 0.334
regulation of macromolecule biosynthetic process GO:0010556 225 0.329
heart valve formation GO:0003188 4 0.328
regulation of rna metabolic process GO:0051252 224 0.324
megakaryocyte differentiation GO:0030219 1 0.314
biosynthetic process GO:0009058 294 0.304
convergent extension GO:0060026 118 0.287
myeloid leukocyte differentiation GO:0002573 15 0.285
cellular biosynthetic process GO:0044249 286 0.283
regulation of gene expression GO:0010468 265 0.278
response to external biotic stimulus GO:0043207 97 0.268
specification of symmetry GO:0009799 204 0.266
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.266
atrioventricular valve formation GO:0003190 3 0.265
immune response GO:0006955 28 0.264
cellular nitrogen compound metabolic process GO:0034641 290 0.261
regulation of nodal signaling pathway GO:1900107 4 0.255
heterocycle biosynthetic process GO:0018130 215 0.252
regulation of cell differentiation GO:0045595 142 0.248
organic cyclic compound metabolic process GO:1901360 301 0.242
regulation of nucleic acid templated transcription GO:1903506 213 0.241
rna biosynthetic process GO:0032774 181 0.239
negative regulation of leukocyte differentiation GO:1902106 1 0.236
dna methylation or demethylation GO:0044728 8 0.233
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.233
regulation of myeloid leukocyte differentiation GO:0002761 5 0.221
regulation of erythrocyte differentiation GO:0045646 2 0.219
regulation of cardiac muscle tissue development GO:0055024 1 0.213
heart looping GO:0001947 94 0.210
liver development GO:0001889 96 0.203
heart field specification GO:0003128 1 0.195
regulation of ectodermal cell fate specification GO:0042665 2 0.192
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.181
atrial ventricular junction remodeling GO:0003294 2 0.178
granulocyte differentiation GO:0030851 8 0.172
muscle structure development GO:0061061 196 0.171
nerve development GO:0021675 45 0.171
regulation of bmp signaling pathway GO:0030510 39 0.167
striated muscle cell differentiation GO:0051146 129 0.165
organic cyclic compound biosynthetic process GO:1901362 223 0.163
regulation of multicellular organismal process GO:0051239 277 0.160
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.158
immune system development GO:0002520 191 0.155
negative regulation of myeloid leukocyte differentiation GO:0002762 1 0.154
cilium movement involved in cell motility GO:0060294 3 0.145
immune system process GO:0002376 241 0.144
rna metabolic process GO:0016070 219 0.142
death GO:0016265 121 0.141
positive regulation of nucleic acid templated transcription GO:1903508 57 0.135
embryonic heart tube development GO:0035050 133 0.128
positive regulation of gene expression GO:0010628 71 0.127
positive regulation of biological process GO:0048518 253 0.122
pancreas development GO:0031016 84 0.121
transition metal ion transport GO:0000041 6 0.121
response to lipid GO:0033993 60 0.120
enzyme linked receptor protein signaling pathway GO:0007167 106 0.120
heart contraction GO:0060047 71 0.116
immune effector process GO:0002252 23 0.114
homeostasis of number of cells GO:0048872 62 0.113
iron ion transport GO:0006826 4 0.113
regulation of metabolic process GO:0019222 359 0.112
macrophage differentiation GO:0030225 7 0.112
myeloid cell homeostasis GO:0002262 56 0.109
mesodermal to mesenchymal transition involved in gastrulation GO:0060809 1 0.109
cardiac muscle tissue development GO:0048738 48 0.109
hepaticobiliary system development GO:0061008 98 0.108
embryonic organ development GO:0048568 381 0.107
regulation of developmental process GO:0050793 247 0.106
heterocycle metabolic process GO:0046483 290 0.106
collagen metabolic process GO:0032963 2 0.101
female gonad development GO:0008585 4 0.099
regulation of cell proliferation involved in heart morphogenesis GO:2000136 2 0.098
larval development GO:0002164 2 0.098
nucleobase containing compound metabolic process GO:0006139 274 0.095
myeloid cell differentiation GO:0030099 86 0.094
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.093
gene expression GO:0010467 252 0.089
monocyte differentiation GO:0030224 2 0.088
primitive hemopoiesis GO:0060215 27 0.086
nucleic acid templated transcription GO:0097659 181 0.083
regulation of immune system process GO:0002682 34 0.083
negative regulation of mesodermal cell fate specification GO:0042662 3 0.083
septum transversum development GO:0003343 4 0.083
hematopoietic progenitor cell differentiation GO:0002244 23 0.082
negative regulation of granulocyte differentiation GO:0030853 1 0.081
positive regulation of rna metabolic process GO:0051254 59 0.079
regulation of neutrophil differentiation GO:0045658 3 0.077
epithelial tube morphogenesis GO:0060562 148 0.077
regulation of multicellular organismal development GO:2000026 223 0.076
morphogenesis of an epithelium GO:0002009 333 0.074
signal transduction GO:0007165 455 0.074
ectodermal cell fate specification GO:0001715 2 0.074
regulation of myeloid cell differentiation GO:0045637 8 0.073
regulation of wnt signaling pathway involved in heart development GO:0003307 2 0.072
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.071
regulation of reproductive process GO:2000241 4 0.070
regulation of transcription dna templated GO:0006355 213 0.070
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.068
protein metabolic process GO:0019538 183 0.067
cell migration to the midline involved in heart development GO:0003318 12 0.067
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.067
negative regulation of cellular biosynthetic process GO:0031327 55 0.067
platelet formation GO:0030220 1 0.066
negative regulation of gene expression GO:0010629 65 0.065
regulation of ectoderm development GO:2000383 2 0.065
positive regulation of transcription dna templated GO:0045893 57 0.065
determination of left right asymmetry in diencephalon GO:0035462 4 0.064
regulation of cell communication GO:0010646 232 0.062
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.062
negative regulation of myeloid cell differentiation GO:0045638 1 0.062
ectodermal cell fate commitment GO:0001712 2 0.062
regulation of protein complex assembly GO:0043254 3 0.061
hematopoietic stem cell migration GO:0035701 4 0.061
positive regulation of macromolecule metabolic process GO:0010604 93 0.058
cardiogenic plate morphogenesis GO:0003142 1 0.058
optic placode formation involved in camera type eye formation GO:0046619 3 0.057
regulation of biosynthetic process GO:0009889 250 0.057
atrioventricular valve development GO:0003171 11 0.055
negative regulation of multicellular organismal process GO:0051241 69 0.054
multicellular organismal metabolic process GO:0044236 2 0.053
posterior lateral line development GO:0048916 38 0.053
regulation of cell activation GO:0050865 1 0.053
embryonic heart tube left right pattern formation GO:0060971 5 0.053
heart valve development GO:0003170 14 0.052
nuclear transport GO:0051169 4 0.052
atrioventricular valve morphogenesis GO:0003181 6 0.051
negative regulation of chromosome organization GO:2001251 1 0.051
muscle cell differentiation GO:0042692 139 0.050
regulation of macromolecule metabolic process GO:0060255 317 0.050
cellular protein metabolic process GO:0044267 129 0.050
ectodermal cell differentiation GO:0010668 2 0.049
gastrulation with mouth forming second GO:0001702 44 0.049
response to stress GO:0006950 263 0.049
astrocyte differentiation GO:0048708 1 0.048
cellular protein catabolic process GO:0044257 4 0.047
positive regulation of neuron migration GO:2001224 2 0.047
definitive hemopoiesis GO:0060216 18 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.046
positive regulation of rna biosynthetic process GO:1902680 57 0.046
response to fluid shear stress GO:0034405 2 0.046
response to external stimulus GO:0009605 264 0.045
mesenchyme development GO:0060485 127 0.045
cellular response to stress GO:0033554 62 0.044
regulation of nitrogen compound metabolic process GO:0051171 251 0.044
intermediate mesoderm development GO:0048389 2 0.044
cardiac muscle cell differentiation GO:0055007 30 0.043
sensory organ development GO:0007423 393 0.042
cell proliferation involved in heart morphogenesis GO:0061323 2 0.041
regulation of cell death GO:0010941 103 0.041
response to axon injury GO:0048678 14 0.041
response to biotic stimulus GO:0009607 97 0.040
negative regulation of biological process GO:0048519 304 0.040
determination of left right asymmetry in nervous system GO:0035545 4 0.039
digestive tract morphogenesis GO:0048546 231 0.038
antimicrobial humoral response GO:0019730 2 0.038
regulation of cytokine production GO:0001817 3 0.038
nodal signaling pathway GO:0038092 7 0.038
muscle tissue development GO:0060537 110 0.038
muscle organ development GO:0007517 101 0.037
heart development GO:0007507 313 0.037
cardiac atrium morphogenesis GO:0003209 2 0.036
response to endogenous stimulus GO:0009719 83 0.036
negative regulation of mesoderm development GO:2000381 5 0.036
cell death GO:0008219 121 0.036
heart formation GO:0060914 13 0.034
negative regulation of transcription dna templated GO:0045892 45 0.034
response to chemical GO:0042221 320 0.033
homeostatic process GO:0042592 142 0.033
cardiac ventricle development GO:0003231 9 0.033
digestive system development GO:0055123 289 0.033
regulation of response to stress GO:0080134 36 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 22 0.032
positive regulation of myeloid cell differentiation GO:0045639 2 0.032
peptide metabolic process GO:0006518 1 0.031
cellular amide metabolic process GO:0043603 4 0.031
megakaryocyte development GO:0035855 1 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.030
endoderm formation GO:0001706 29 0.030
response to vitamin GO:0033273 3 0.029
protein complex assembly GO:0006461 30 0.029
formation of primary germ layer GO:0001704 62 0.029
dna methylation GO:0006306 8 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.028
actin filament polymerization GO:0030041 2 0.028
cell migration GO:0016477 237 0.027
neuron development GO:0048666 262 0.027
organism emergence from protective structure GO:0071684 4 0.027
cellular response to chemical stimulus GO:0070887 157 0.027
negative regulation of cell differentiation GO:0045596 46 0.027
fin morphogenesis GO:0033334 53 0.026
response to other organism GO:0051707 97 0.026
canonical wnt signaling pathway GO:0060070 48 0.026
negative regulation of chromatin modification GO:1903309 1 0.025
innate immune response GO:0045087 13 0.025
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.025
defense response GO:0006952 47 0.024
ectoderm formation GO:0001705 2 0.024
negative regulation of protein complex assembly GO:0031333 1 0.024
rhombomere 5 development GO:0021571 4 0.024
negative regulation of cell fate commitment GO:0010454 13 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.024
regulation of collateral sprouting in absence of injury GO:0048696 4 0.024
heart valve morphogenesis GO:0003179 8 0.023
positive regulation of jun kinase activity GO:0043507 2 0.023
heart process GO:0003015 71 0.023
cardiac chamber morphogenesis GO:0003206 12 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.023
generation of neurons GO:0048699 385 0.023
leukocyte differentiation GO:0002521 25 0.022
dorsal aorta morphogenesis GO:0035912 3 0.022
regulation of response to stimulus GO:0048583 269 0.022
aging GO:0007568 2 0.022
regulation of establishment of protein localization GO:0070201 4 0.022
regionalization GO:0003002 274 0.021
negative regulation of cellular process GO:0048523 283 0.021
multicellular organismal macromolecule metabolic process GO:0044259 2 0.021
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.021
cardiac ventricle formation GO:0003211 1 0.021
convergent extension involved in organogenesis GO:0060029 10 0.021
cell cell adhesion involved in gastrulation GO:0070586 4 0.021
growth GO:0040007 174 0.020
cell projection organization GO:0030030 284 0.020
inner ear receptor cell fate commitment GO:0060120 4 0.020
regulation of stem cell differentiation GO:2000736 4 0.020
non canonical wnt signaling pathway involved in heart development GO:0061341 2 0.020
mesodermal cell fate specification GO:0007501 12 0.020
positive regulation of dna templated transcription elongation GO:0032786 1 0.020
methylation GO:0032259 22 0.020
cardiac atrium development GO:0003230 4 0.020
positive regulation of biosynthetic process GO:0009891 68 0.020
spermatid development GO:0007286 2 0.020
regulation of activin receptor signaling pathway GO:0032925 5 0.020
endodermal cell fate determination GO:0007493 2 0.020
mesoderm development GO:0007498 88 0.019
regulation of heart growth GO:0060420 2 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.019
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 1 0.019
dorsal aorta development GO:0035907 4 0.019
positive regulation of cellular component biogenesis GO:0044089 3 0.019
positive regulation of cellular process GO:0048522 201 0.019
regulation of signal transduction GO:0009966 225 0.019
cardioblast migration GO:0003260 7 0.018
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.018
cardiac chamber development GO:0003205 19 0.018
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.018
cranial nerve development GO:0021545 42 0.018
locomotion GO:0040011 313 0.018
hemopoiesis GO:0030097 183 0.017
regulation of macrophage differentiation GO:0045649 1 0.017
programmed cell death GO:0012501 119 0.017
negative regulation of nucleic acid templated transcription GO:1903507 45 0.017
foregut morphogenesis GO:0007440 4 0.017
regulation of nucleotide metabolic process GO:0006140 17 0.017
compound eye development GO:0048749 2 0.017
proteolysis GO:0006508 38 0.017
fin development GO:0033333 77 0.017
regulation of cysteine type endopeptidase activity GO:2000116 21 0.016
immunoglobulin mediated immune response GO:0016064 3 0.016
renal system process involved in regulation of blood volume GO:0001977 1 0.016
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.016
response to oxygen containing compound GO:1901700 55 0.016
regulation of cytokine biosynthetic process GO:0042035 1 0.016
regulation of dna methylation GO:0044030 5 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.016
positive regulation of protein complex assembly GO:0031334 2 0.015
embryonic foregut morphogenesis GO:0048617 1 0.015
b cell activation GO:0042113 2 0.015
ectodermal placode morphogenesis GO:0071697 32 0.015
regulation of biological quality GO:0065008 263 0.015
response to organic cyclic compound GO:0014070 51 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
mesendoderm development GO:0048382 10 0.015
dna modification GO:0006304 8 0.015
positive regulation of jnk cascade GO:0046330 3 0.015
platelet morphogenesis GO:0036344 1 0.015
cytoskeleton organization GO:0007010 96 0.015
negative regulation of muscle tissue development GO:1901862 2 0.015
mesenchymal cell differentiation GO:0048762 87 0.014
regulation of oocyte development GO:0060281 3 0.014
regulation of mitotic cell cycle GO:0007346 25 0.014
positive regulation of cellular biosynthetic process GO:0031328 68 0.014
negative regulation of cytokine production GO:0001818 1 0.014
dna alkylation GO:0006305 8 0.014
maintenance of location GO:0051235 4 0.014
catabolic process GO:0009056 32 0.014
gland development GO:0048732 143 0.014
tissue regeneration GO:0042246 74 0.014
regulation of bmp signaling pathway involved in heart jogging GO:2000223 12 0.014
humoral immune response mediated by circulating immunoglobulin GO:0002455 3 0.014
regulation of response to external stimulus GO:0032101 31 0.014
artery development GO:0060840 22 0.014
embryonic organ morphogenesis GO:0048562 274 0.014
ventricular cardiac muscle tissue development GO:0003229 3 0.014
positive regulation of transport GO:0051050 2 0.014
cardiac conduction system development GO:0003161 1 0.014
mesoderm formation GO:0001707 43 0.013
small molecule metabolic process GO:0044281 77 0.013
positive regulation of catabolic process GO:0009896 4 0.013
organic substance catabolic process GO:1901575 28 0.013
blood circulation GO:0008015 87 0.013
palate development GO:0060021 8 0.013
organonitrogen compound metabolic process GO:1901564 74 0.013
regulation of bone mineralization GO:0030500 2 0.013
regulation of signaling GO:0023051 235 0.013
gastrulation GO:0007369 208 0.013
response to alcohol GO:0097305 14 0.013
outflow tract morphogenesis GO:0003151 1 0.013
angiogenesis GO:0001525 158 0.013
cytokine metabolic process GO:0042107 1 0.013
angioblast cell migration GO:0035476 9 0.013
regulation of canonical wnt signaling pathway GO:0060828 34 0.013
cell part morphogenesis GO:0032990 246 0.013
somatic stem cell maintenance GO:0035019 1 0.013
brain development GO:0007420 293 0.012
response to organic substance GO:0010033 153 0.012
optic nerve morphogenesis GO:0021631 6 0.012
nitric oxide metabolic process GO:0046209 2 0.012
bmp signaling pathway involved in heart development GO:0061312 15 0.012
cell migration involved in heart development GO:0060973 22 0.012
positive regulation of neural retina development GO:0061075 1 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
regulation of cellular extravasation GO:0002691 1 0.011
response to glucocorticoid GO:0051384 1 0.011
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 10 0.011
olfactory bulb development GO:0021772 4 0.011
neutrophil differentiation GO:0030223 6 0.011
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.011
protein acylation GO:0043543 3 0.011
cellular response to starvation GO:0009267 1 0.011
positive regulation of map kinase activity GO:0043406 3 0.011
regulation of biomineral tissue development GO:0070167 2 0.011
calcium ion homeostasis GO:0055074 19 0.011
positive regulation of cell activation GO:0050867 1 0.011
toll like receptor signaling pathway GO:0002224 4 0.011
amide biosynthetic process GO:0043604 1 0.011
aorta development GO:0035904 4 0.011
glial cell differentiation GO:0010001 42 0.011
regulation of rho protein signal transduction GO:0035023 2 0.011
negative regulation of developmental process GO:0051093 65 0.011
spemann organizer formation GO:0060061 10 0.011
positive regulation of developmental process GO:0051094 50 0.011
carbohydrate derivative metabolic process GO:1901135 61 0.011
growth plate cartilage development GO:0003417 2 0.011
ion transport GO:0006811 114 0.011
response to wounding GO:0009611 116 0.011
wnt signaling pathway involved in heart development GO:0003306 5 0.011
limb bud formation GO:0060174 2 0.011
regulation of cardiac chamber morphogenesis GO:1901219 2 0.011
cellular response to external stimulus GO:0071496 2 0.011
ear morphogenesis GO:0042471 64 0.011
epithelial cell morphogenesis GO:0003382 2 0.011
lymphocyte proliferation GO:0046651 1 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
regulation of myelination GO:0031641 1 0.010
positive regulation of neurogenesis GO:0050769 24 0.010
protein k48 linked ubiquitination GO:0070936 1 0.010
negative regulation of histone modification GO:0031057 1 0.010
regulation of heart morphogenesis GO:2000826 17 0.010
pectoral fin development GO:0033339 50 0.010
centrosome cycle GO:0007098 1 0.010
striated muscle tissue development GO:0014706 110 0.010
regulation of cardiac muscle cell differentiation GO:2000725 1 0.010
positive regulation of muscle organ development GO:0048636 1 0.010
reactive oxygen species biosynthetic process GO:1903409 1 0.010
morphogenesis of embryonic epithelium GO:0016331 30 0.010

drl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.036
disease of cellular proliferation DOID:14566 0 0.036