Danio rerio

34 known processes

flt1

fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

(Aliases: VEGFR1,flt1b,sFlt1)

flt1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
blood vessel morphogenesis GO:0048514 216 0.727
vascular endothelial growth factor receptor signaling pathway GO:0048010 13 0.696
Human Zebrafish Mouse
lymph vessel development GO:0001945 27 0.694
Zebrafish
sprouting angiogenesis GO:0002040 53 0.564
positive regulation of cell matrix adhesion GO:0001954 1 0.551
vasculature development GO:0001944 278 0.544
embryonic organ development GO:0048568 381 0.519
Zebrafish Fly
heart development GO:0007507 313 0.513
Zebrafish
response to stress GO:0006950 263 0.509
Mouse Rat Fly
vasculogenesis GO:0001570 41 0.502
blood vessel development GO:0001568 246 0.497
lymphangiogenesis GO:0001946 25 0.478
Zebrafish
smooth muscle contraction GO:0006939 2 0.468
Zebrafish Rat
cell surface receptor signaling pathway GO:0007166 325 0.465
Human Zebrafish Mouse Rat
response to external stimulus GO:0009605 264 0.438
Human Zebrafish Fly
response to chemical GO:0042221 320 0.430
Human Zebrafish Mouse Rat Fly
artery morphogenesis GO:0048844 14 0.420
Zebrafish
lymph vessel morphogenesis GO:0036303 25 0.411
Zebrafish
locomotion GO:0040011 313 0.404
Human Zebrafish Mouse Rat Fly
regulation of metabolic process GO:0019222 359 0.388
Human Rat Fly
ameboidal type cell migration GO:0001667 143 0.377
Zebrafish Fly
artery development GO:0060840 22 0.356
Zebrafish
positive regulation of endothelial cell proliferation GO:0001938 1 0.356
cell substrate adhesion GO:0031589 4 0.346
actin cytoskeleton organization GO:0030036 63 0.323
Fly
regulation of retina development in camera type eye GO:1902866 2 0.323
Zebrafish
cell projection assembly GO:0030031 64 0.320
Fly
cellular biosynthetic process GO:0044249 286 0.315
eye development GO:0001654 277 0.313
Zebrafish
macrophage chemotaxis GO:0048246 3 0.311
Zebrafish
signal transduction GO:0007165 455 0.311
Human Zebrafish Mouse Rat Fly
regulation of response to stimulus GO:0048583 269 0.309
Human Zebrafish Rat Fly
endothelial cell proliferation GO:0001935 11 0.306
heart contraction GO:0060047 71 0.306
cellular component morphogenesis GO:0032989 336 0.303
Fly
regulation of multicellular organismal development GO:2000026 223 0.300
Human Zebrafish Mouse
neural retina development GO:0003407 49 0.299
Zebrafish
single organism localization GO:1902578 225 0.289
system process GO:0003008 185 0.287
regulation of endothelial cell proliferation GO:0001936 1 0.280
embryonic heart tube development GO:0035050 133 0.276
Zebrafish
pigmentation GO:0043473 85 0.275
Zebrafish
regulation of system process GO:0044057 40 0.273
embryo development ending in birth or egg hatching GO:0009792 271 0.268
macrophage differentiation GO:0030225 7 0.264
Zebrafish
positive regulation of cell substrate adhesion GO:0010811 1 0.260
sensory organ development GO:0007423 393 0.253
Zebrafish
angiogenesis GO:0001525 158 0.244
regulation of cell substrate adhesion GO:0010810 1 0.244
nucleobase containing compound metabolic process GO:0006139 274 0.239
single organism transport GO:0044765 206 0.234
cell matrix adhesion GO:0007160 4 0.231
muscle contraction GO:0006936 18 0.224
Zebrafish Rat
ovulation cycle process GO:0022602 2 0.224
negative regulation of angiogenesis GO:0016525 7 0.220
cellular macromolecule biosynthetic process GO:0034645 224 0.215
mesenchymal cell proliferation GO:0010463 1 0.214
nitrogen compound metabolic process GO:0006807 319 0.209
positive regulation of secretion GO:0051047 1 0.204
positive regulation of gtp catabolic process GO:0033126 1 0.197
regulation of cell matrix adhesion GO:0001952 1 0.197
inositol lipid mediated signaling GO:0048017 2 0.189
Human
cellular aromatic compound metabolic process GO:0006725 295 0.185
heterocycle biosynthetic process GO:0018130 215 0.182
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.179
erk1 and erk2 cascade GO:0070371 4 0.179
organic substance biosynthetic process GO:1901576 289 0.176
regulation of localization GO:0032879 104 0.174
Human Zebrafish Rat
regulation of signal transduction GO:0009966 225 0.174
Human Rat Fly
negative regulation of biological process GO:0048519 304 0.172
Fly
somitogenesis GO:0001756 87 0.164
protein localization to nucleus GO:0034504 3 0.163
gland development GO:0048732 143 0.163
Zebrafish Fly
guanosine containing compound metabolic process GO:1901068 4 0.160
g protein coupled receptor signaling pathway GO:0007186 74 0.158
actin filament based process GO:0030029 64 0.158
Fly
regulation of epithelial cell proliferation GO:0050678 3 0.156
multicellular organismal homeostasis GO:0048871 29 0.155
cellular component biogenesis GO:0044085 178 0.154
Fly
phosphatidylinositol 3 kinase signaling GO:0014065 2 0.153
Human
hemopoiesis GO:0030097 183 0.152
Zebrafish Mouse Fly
positive regulation of cellular process GO:0048522 201 0.151
Human Zebrafish Mouse Rat Fly
regulation of biosynthetic process GO:0009889 250 0.144
positive regulation of leukocyte chemotaxis GO:0002690 1 0.143
Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.143
positive regulation of epithelial cell proliferation GO:0050679 1 0.140
regulation of neural precursor cell proliferation GO:2000177 3 0.139
positive regulation of cellular catabolic process GO:0031331 3 0.136
cellular component movement GO:0006928 335 0.133
Human Zebrafish Mouse Rat Fly
positive regulation of metabolic process GO:0009893 108 0.133
Human Rat Fly
negative regulation of cellular process GO:0048523 283 0.132
Fly
positive regulation of transport GO:0051050 2 0.131
gtp metabolic process GO:0046039 4 0.129
regulation of intracellular protein transport GO:0033157 3 0.127
positive regulation of catabolic process GO:0009896 4 0.126
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.123
Mouse
positive regulation of endothelial cell migration GO:0010595 2 0.123
epithelium migration GO:0090132 25 0.123
Zebrafish Fly
cellular component assembly GO:0022607 170 0.121
Fly
mechanosensory behavior GO:0007638 2 0.120
pigment cell differentiation GO:0050931 38 0.120
Zebrafish
regulation of macromolecule metabolic process GO:0060255 317 0.118
Human Rat
developmental pigmentation GO:0048066 48 0.116
Zebrafish
ion homeostasis GO:0050801 41 0.115
venous blood vessel development GO:0060841 9 0.114
Zebrafish
cognition GO:0050890 1 0.114
antimicrobial humoral response GO:0019730 2 0.113
Fly
cell migration involved in sprouting angiogenesis GO:0002042 8 0.112
regulation of erk1 and erk2 cascade GO:0070372 4 0.112
ovulation cycle GO:0042698 2 0.112
regeneration GO:0031099 91 0.111
cell morphogenesis involved in differentiation GO:0000904 195 0.110
positive regulation of gtpase activity GO:0043547 1 0.109
regulation of nucleotide catabolic process GO:0030811 2 0.108
regulation of stem cell proliferation GO:0072091 2 0.107
regulation of purine nucleotide catabolic process GO:0033121 2 0.106
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.106
heart morphogenesis GO:0003007 156 0.106
immune system development GO:0002520 191 0.106
Zebrafish Mouse Fly
regulation of establishment of protein localization GO:0070201 4 0.105
heterocycle metabolic process GO:0046483 290 0.104
organic cyclic compound metabolic process GO:1901360 301 0.104
positive regulation of phospholipase c activity GO:0010863 1 0.102
Human
positive regulation of macromolecule metabolic process GO:0010604 93 0.101
Human Rat
metal ion homeostasis GO:0055065 26 0.101
tube morphogenesis GO:0035239 349 0.101
Mouse Fly
positive regulation of cellular component biogenesis GO:0044089 3 0.100
gene expression GO:0010467 252 0.100
neuron development GO:0048666 262 0.098
nucleic acid metabolic process GO:0090304 244 0.097
behavior GO:0007610 74 0.097
Zebrafish
trabecula morphogenesis GO:0061383 2 0.097
regulation of heart contraction GO:0008016 32 0.097
regulation of primary metabolic process GO:0080090 311 0.096
Human Rat
positive chemotaxis GO:0050918 5 0.096
cell migration GO:0016477 237 0.096
Human Zebrafish Mouse Rat Fly
central nervous system development GO:0007417 387 0.095
Zebrafish Fly
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.094
guanosine containing compound catabolic process GO:1901069 2 0.094
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 8 0.092
Human
regulation of protein transport GO:0051223 3 0.092
cellular macromolecule metabolic process GO:0044260 391 0.092
Human Zebrafish Mouse Rat
response to decreased oxygen levels GO:0036293 25 0.091
Mouse Rat
osteoclast differentiation GO:0030316 1 0.091
Zebrafish
epithelial cell differentiation GO:0030855 116 0.091
Zebrafish Fly
regulation of cell migration involved in sprouting angiogenesis GO:0090049 3 0.091
single organism metabolic process GO:0044710 217 0.090
Human Rat Fly
regulation of vasculogenesis GO:2001212 1 0.090
response to wounding GO:0009611 116 0.090
cell morphogenesis GO:0000902 289 0.089
Fly
biological adhesion GO:0022610 40 0.089
establishment of localization GO:0051234 244 0.088
regulation of cell differentiation GO:0045595 142 0.088
Mouse Fly
melanocyte differentiation GO:0030318 26 0.088
Zebrafish
positive regulation of epithelial cell migration GO:0010634 2 0.087
cell part morphogenesis GO:0032990 246 0.087
regulation of gtp catabolic process GO:0033124 2 0.087
regulation of leukocyte migration GO:0002685 8 0.086
Zebrafish
positive regulation of secretion by cell GO:1903532 1 0.086
regulation of dna replication GO:0006275 3 0.085
regulation of cellular metabolic process GO:0031323 320 0.084
Human Rat Fly
regulation of anatomical structure morphogenesis GO:0022603 130 0.084
Human Fly
camera type eye development GO:0043010 222 0.084
Zebrafish
regulation of mesenchymal cell proliferation GO:0010464 1 0.083
cellular protein metabolic process GO:0044267 129 0.082
Human Zebrafish Mouse Rat
mononuclear cell migration GO:0071674 1 0.082
Zebrafish
positive regulation of nucleotide catabolic process GO:0030813 1 0.081
establishment of protein localization to organelle GO:0072594 4 0.081
regulation of protein localization to nucleus GO:1900180 2 0.080
female gonad development GO:0008585 4 0.080
regulation of immune system process GO:0002682 34 0.079
Zebrafish Mouse Fly
circulatory system process GO:0003013 87 0.077
positive regulation of stem cell proliferation GO:2000648 1 0.077
somite development GO:0061053 96 0.076
microtubule based process GO:0007017 60 0.076
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.076
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.076
phosphatidylinositol mediated signaling GO:0048015 2 0.075
Human
homeostasis of number of cells GO:0048872 62 0.075
Fly
positive regulation of nucleoside metabolic process GO:0045979 1 0.074
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.074
positive regulation of response to external stimulus GO:0032103 9 0.074
Zebrafish
dicarboxylic acid transport GO:0006835 1 0.074
cell motility GO:0048870 244 0.073
Human Zebrafish Mouse Rat Fly
cellular response to growth factor stimulus GO:0071363 39 0.073
Human Mouse Rat
organonitrogen compound metabolic process GO:1901564 74 0.073
aromatic compound biosynthetic process GO:0019438 217 0.072
regulation of cell development GO:0060284 100 0.072
hematopoietic or lymphoid organ development GO:0048534 191 0.072
Zebrafish Mouse Fly
cell substrate adherens junction assembly GO:0007045 1 0.072
tissue homeostasis GO:0001894 25 0.072
thyroid gland development GO:0030878 12 0.072
Zebrafish
divalent inorganic cation homeostasis GO:0072507 22 0.071
regulation of neurogenesis GO:0050767 87 0.071
glial cell differentiation GO:0010001 42 0.071
Zebrafish
regulation of angiogenesis GO:0045765 26 0.069
Human
single organism reproductive process GO:0044702 40 0.068
Fly
positive regulation of biological process GO:0048518 253 0.068
Human Zebrafish Mouse Rat Fly
regulation of nucleocytoplasmic transport GO:0046822 2 0.068
cell proliferation GO:0008283 80 0.068
Rat
multicellular organismal reproductive process GO:0048609 35 0.067
Fly
epithelial cell migration GO:0010631 25 0.067
Zebrafish Fly
positive regulation of neural precursor cell proliferation GO:2000179 1 0.067
ovarian follicle development GO:0001541 2 0.067
osteoclast development GO:0036035 1 0.067
Zebrafish
organic cyclic compound biosynthetic process GO:1901362 223 0.066
protein import into nucleus GO:0006606 3 0.066
regulation of biological quality GO:0065008 263 0.065
Fly
protein secretion GO:0009306 1 0.065
retina development in camera type eye GO:0060041 146 0.065
Zebrafish
regulation of cell communication GO:0010646 232 0.065
Human Rat Fly
response to organic substance GO:0010033 153 0.064
Human Mouse Rat Fly
calcium mediated signaling GO:0019722 2 0.064
regulation of blood circulation GO:1903522 32 0.064
response to oxygen containing compound GO:1901700 55 0.064
Fly
transport GO:0006810 220 0.063
response to external biotic stimulus GO:0043207 97 0.063
Fly
wound healing GO:0042060 90 0.063
macromolecule biosynthetic process GO:0009059 227 0.062
vascular endothelial growth factor signaling pathway GO:0038084 3 0.062
Human Mouse Rat
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.062
localization of cell GO:0051674 244 0.061
Human Zebrafish Mouse Rat Fly
establishment of localization in cell GO:0051649 77 0.061
muscle system process GO:0003012 20 0.061
Zebrafish Rat
stem cell proliferation GO:0072089 4 0.061
immune system process GO:0002376 241 0.059
Human Zebrafish Mouse Fly
protein targeting to nucleus GO:0044744 3 0.059
response to biotic stimulus GO:0009607 97 0.059
Fly
cell substrate junction assembly GO:0007044 2 0.059
blood vessel endothelial cell migration GO:0043534 18 0.058
Zebrafish
nucleocytoplasmic transport GO:0006913 4 0.058
blood circulation GO:0008015 87 0.058
regulation of vasculature development GO:1901342 33 0.058
Human
blood vessel endothelial cell proliferation involved in sprouting angiogenesis GO:0002043 4 0.057
endocardium development GO:0003157 9 0.056
myeloid leukocyte differentiation GO:0002573 15 0.056
Zebrafish
aging GO:0007568 2 0.056
regulation of signaling GO:0023051 235 0.056
Human Rat Fly
regulation of protein targeting GO:1903533 2 0.055
development of primary female sexual characteristics GO:0046545 4 0.055
intracellular signal transduction GO:0035556 85 0.055
Human Rat Fly
epithelial tube morphogenesis GO:0060562 148 0.055
Mouse Fly
endocrine system development GO:0035270 65 0.055
Zebrafish
positive regulation of cell communication GO:0010647 56 0.055
Human Rat Fly
regulation of cell morphogenesis GO:0022604 42 0.054
Fly
inorganic cation transmembrane transport GO:0098662 50 0.054
cellular nitrogen compound biosynthetic process GO:0044271 218 0.054
regulation of cytoplasmic transport GO:1903649 4 0.054
response to nitrogen compound GO:1901698 19 0.054
Fly
cellular response to hormone stimulus GO:0032870 39 0.054
Fly
extrinsic apoptotic signaling pathway GO:0097191 3 0.053
regulation of neural retina development GO:0061074 2 0.053
Zebrafish
granulocyte chemotaxis GO:0071621 11 0.052
Zebrafish
ubiquitin dependent protein catabolic process GO:0006511 3 0.052
positive regulation of immune system process GO:0002684 17 0.052
Zebrafish Mouse
macromolecular complex subunit organization GO:0043933 74 0.052
Fly
adherens junction organization GO:0034332 4 0.051
digestive system development GO:0055123 289 0.051
Fly
regulation of developmental process GO:0050793 247 0.051
Human Zebrafish Mouse Fly
amine metabolic process GO:0009308 2 0.051
nuclear import GO:0051170 3 0.050
adherens junction assembly GO:0034333 1 0.050
actin filament organization GO:0007015 15 0.050
Fly
regulation of cell motility GO:2000145 46 0.050
Human Zebrafish Rat
regulation of phosphorus metabolic process GO:0051174 43 0.050
Human Rat Fly
neurotransmitter transport GO:0006836 2 0.049
cellular response to organic substance GO:0071310 105 0.049
Human Mouse Rat Fly
signal transduction by phosphorylation GO:0023014 18 0.049
Human Rat Fly
positive regulation of map kinase activity GO:0043406 3 0.048
Human Rat
axon development GO:0061564 166 0.048
enzyme linked receptor protein signaling pathway GO:0007167 106 0.048
Human Zebrafish Mouse Rat
cell projection organization GO:0030030 284 0.047
Fly
response to mechanical stimulus GO:0009612 24 0.046
rna biosynthetic process GO:0032774 181 0.046
protein complex subunit organization GO:0071822 46 0.046
Fly
anatomical structure homeostasis GO:0060249 36 0.046
small gtpase mediated signal transduction GO:0007264 8 0.046
columnar cuboidal epithelial cell differentiation GO:0002065 38 0.045
Zebrafish Fly
chordate embryonic development GO:0043009 271 0.045
cell chemotaxis GO:0060326 17 0.045
Human Zebrafish
regulation of cell migration GO:0030334 40 0.045
Human Zebrafish Rat
positive regulation of cell adhesion GO:0045785 1 0.045
regulation of multicellular organismal process GO:0051239 277 0.045
bmp signaling pathway GO:0030509 52 0.045
negative regulation of multicellular organismal process GO:0051241 69 0.045
protein heterooligomerization GO:0051291 1 0.044
specification of symmetry GO:0009799 204 0.044
positive regulation of response to stimulus GO:0048584 80 0.044
Human Zebrafish Rat Fly
lipid catabolic process GO:0016042 4 0.044
female sex differentiation GO:0046660 4 0.043
nik nf kappab signaling GO:0038061 1 0.043
dorsal aorta morphogenesis GO:0035912 3 0.043
apoptotic process GO:0006915 116 0.043
Zebrafish Fly
endothelial cell migration GO:0043542 19 0.043
Zebrafish
response to hypoxia GO:0001666 25 0.043
Mouse Rat
neurotransmitter secretion GO:0007269 2 0.042
tissue remodeling GO:0048771 4 0.042
regulation of catalytic activity GO:0050790 55 0.041
Human Rat
cellular amino acid metabolic process GO:0006520 7 0.041
transcription dna templated GO:0006351 181 0.041
regulation of cellular biosynthetic process GO:0031326 245 0.041
cation transmembrane transport GO:0098655 65 0.041
endocrine process GO:0050886 2 0.040
regulation of hydrolase activity GO:0051336 28 0.040
Human
cellular amine metabolic process GO:0044106 2 0.040
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.040
cell fate commitment GO:0045165 99 0.040
immune response GO:0006955 28 0.040
Fly
heart trabecula morphogenesis GO:0061384 2 0.040
glomerulus vasculature development GO:0072012 2 0.039
regulation of rac protein signal transduction GO:0035020 1 0.039
calcium ion homeostasis GO:0055074 19 0.039
regulation of transport GO:0051049 45 0.039
regulation of gtpase activity GO:0043087 2 0.039
cell death GO:0008219 121 0.039
Zebrafish Fly
determination of left right symmetry GO:0007368 179 0.039
neuron differentiation GO:0030182 353 0.039
regulation of protein metabolic process GO:0051246 56 0.039
Human Rat
nucleobase containing compound biosynthetic process GO:0034654 205 0.039
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.038
Human Zebrafish Mouse Rat
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.038
positive regulation of cell cycle GO:0045787 3 0.038
macromolecule modification GO:0043412 111 0.038
Human Zebrafish Mouse Rat
regulation of nucleic acid templated transcription GO:1903506 213 0.038
regulation of blood vessel size GO:0050880 2 0.038
regulation of tube size GO:0035150 2 0.037
brain development GO:0007420 293 0.036
cell adhesion GO:0007155 40 0.036
microtubule based movement GO:0007018 33 0.036
cellular protein catabolic process GO:0044257 4 0.036
organ regeneration GO:0031100 1 0.036
regulation of synaptic plasticity GO:0048167 1 0.036
larval development GO:0002164 2 0.036
response to growth factor GO:0070848 39 0.036
Human Mouse Rat
positive regulation of macrophage chemotaxis GO:0010759 1 0.035
Zebrafish
cardiac cell fate commitment GO:0060911 1 0.035
regulation of positive chemotaxis GO:0050926 4 0.035
morphogenesis of an epithelium GO:0002009 333 0.035
Mouse Fly
negative regulation of secretion GO:0051048 2 0.035
segmentation GO:0035282 97 0.035
transcription from rna polymerase ii promoter GO:0006366 80 0.035
regulation of cytokine production GO:0001817 3 0.035
regulation of molecular function GO:0065009 70 0.035
Human Rat
small molecule metabolic process GO:0044281 77 0.035
regulation of endothelial cell differentiation GO:0045601 3 0.035
embryonic organ morphogenesis GO:0048562 274 0.034
response to endogenous stimulus GO:0009719 83 0.034
Fly
modification dependent protein catabolic process GO:0019941 3 0.034
reproductive process GO:0022414 40 0.034
Fly
positive regulation of positive chemotaxis GO:0050927 4 0.034
modification dependent macromolecule catabolic process GO:0043632 3 0.034
rhythmic process GO:0048511 21 0.034
regulation of macromolecule biosynthetic process GO:0010556 225 0.033
response to other organism GO:0051707 97 0.033
Fly
protein phosphorylation GO:0006468 47 0.033
Human Zebrafish Mouse Rat
morphogenesis of an epithelial sheet GO:0002011 49 0.033
regulation of behavior GO:0050795 24 0.033
Zebrafish
regulation of chemotaxis GO:0050920 18 0.033
Zebrafish
regulation of nik nf kappab signaling GO:1901222 1 0.033
regulation of nucleoside metabolic process GO:0009118 2 0.033
regulation of rna biosynthetic process GO:2001141 213 0.033
outflow tract morphogenesis GO:0003151 1 0.032
hormone transport GO:0009914 2 0.032
amino acid transport GO:0006865 2 0.032
regulation of epithelial cell migration GO:0010632 5 0.032
regulation of hormone secretion GO:0046883 2 0.032
rho protein signal transduction GO:0007266 5 0.032
phosphorus metabolic process GO:0006793 109 0.031
Human Zebrafish Mouse Rat Fly
regulation of muscle contraction GO:0006937 3 0.031
Rat
negative regulation of synapse assembly GO:0051964 2 0.031
positive regulation of catalytic activity GO:0043085 25 0.031
Human Rat
ventricular cardiac muscle tissue morphogenesis GO:0055010 2 0.031
positive regulation of biosynthetic process GO:0009891 68 0.031
response to alkaloid GO:0043279 2 0.031
negative regulation of neural precursor cell proliferation GO:2000178 1 0.030
germ line stem cell maintenance GO:0030718 2 0.030
aorta morphogenesis GO:0035909 3 0.030
phagocytosis GO:0006909 3 0.030
signal transduction in absence of ligand GO:0038034 1 0.030
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.030
exocytosis GO:0006887 1 0.029
reproduction GO:0000003 40 0.029
Fly
ventral spinal cord development GO:0021517 35 0.029
organophosphate metabolic process GO:0019637 37 0.029
Human
regulation of cellular amine metabolic process GO:0033238 0 0.029
hormone secretion GO:0046879 2 0.029
positive regulation of immune effector process GO:0002699 3 0.029
ras protein signal transduction GO:0007265 7 0.029
homeostatic process GO:0042592 142 0.029
Fly
cellular response to chemical stimulus GO:0070887 157 0.029
Human Zebrafish Mouse Rat Fly
negative regulation of cell migration GO:0030336 17 0.029
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.028
hemostasis GO:0007599 13 0.028
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.028
venous endothelial cell migration involved in lymph vessel development GO:0060855 4 0.028
Zebrafish
spinal cord development GO:0021510 46 0.028
response to organonitrogen compound GO:0010243 12 0.028
Fly
phosphorylation GO:0016310 69 0.028
Human Zebrafish Mouse Rat Fly
regulation of cell adhesion GO:0030155 15 0.028
cell projection morphogenesis GO:0048858 244 0.028
myeloid cell differentiation GO:0030099 86 0.028
Zebrafish
positive regulation of signaling GO:0023056 56 0.028
Human Rat Fly
sensory perception of chemical stimulus GO:0007606 3 0.027
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.027
stem cell fate determination GO:0048867 1 0.027
skeletal muscle organ development GO:0060538 78 0.027
generation of neurons GO:0048699 385 0.027
negative regulation of secretion by cell GO:1903531 2 0.027
tissue migration GO:0090130 37 0.027
Zebrafish Fly
microglia differentiation GO:0014004 1 0.027
Zebrafish
kidney development GO:0001822 92 0.026
mechanoreceptor differentiation GO:0042490 37 0.026
negative regulation of sequestering of calcium ion GO:0051283 4 0.026
regulation of production of molecular mediator of immune response GO:0002700 1 0.026
single organism nuclear import GO:1902593 3 0.026
positive regulation of hydrolase activity GO:0051345 13 0.026
Human
cellular protein modification process GO:0006464 100 0.026
Human Zebrafish Mouse Rat
regulation of locomotion GO:0040012 55 0.026
Human Zebrafish Rat
leukocyte chemotaxis GO:0030595 12 0.026
Human Zebrafish
regulation of protein import into nucleus GO:0042306 2 0.026
negative regulation of gliogenesis GO:0014014 1 0.026
negative regulation of developmental process GO:0051093 65 0.026
response to peptide hormone GO:0043434 6 0.025
Fly
biosynthetic process GO:0009058 294 0.025
regulation of inflammatory response GO:0050727 2 0.025
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.025
positive regulation of cytokine production GO:0001819 2 0.025
regulation of rna metabolic process GO:0051252 224 0.025
cation transport GO:0006812 81 0.025
regulation of dendrite development GO:0050773 3 0.025
anterior posterior pattern specification GO:0009952 152 0.025
lateral line system development GO:0048925 76 0.025
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.024
renal system development GO:0072001 94 0.024
Fly
positive regulation of signal transduction GO:0009967 56 0.024
Human Rat Fly
regulation of apoptotic process GO:0042981 98 0.024
Fly
aorta development GO:0035904 4 0.024
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 0 0.024
response to peptide GO:1901652 6 0.024
Fly
actin mediated cell contraction GO:0070252 1 0.024
pericardium morphogenesis GO:0003344 1 0.024
regulation of cell shape GO:0008360 1 0.024
Fly
regulation of phospholipase c activity GO:1900274 1 0.024
Human
protein kinase b signaling GO:0043491 9 0.024
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
regulation of mononuclear cell migration GO:0071675 1 0.024
Zebrafish
taxis GO:0042330 109 0.023
Human Zebrafish
cytokinesis GO:0000910 3 0.023
neuroblast proliferation GO:0007405 2 0.023
regulation of phosphate metabolic process GO:0019220 43 0.023
Human Rat Fly
hypochord development GO:0055016 3 0.023
regulation of cellular component movement GO:0051270 55 0.023
Human Zebrafish Rat
kidney vasculature development GO:0061440 2 0.023
g1 s transition of mitotic cell cycle GO:0000082 1 0.023
chemical homeostasis GO:0048878 49 0.023
developmental growth GO:0048589 166 0.023
positive regulation of cell migration GO:0030335 11 0.023
Human Zebrafish Rat
regulation of response to external stimulus GO:0032101 31 0.022
Zebrafish
ventricular cardiac muscle tissue development GO:0003229 3 0.022
nuclear transport GO:0051169 4 0.022
cell cycle g1 s phase transition GO:0044843 1 0.022
cytosolic calcium ion transport GO:0060401 3 0.022
sensory organ morphogenesis GO:0090596 200 0.022
branching morphogenesis of an epithelial tube GO:0048754 15 0.022
Mouse
regulation of neurotransmitter transport GO:0051588 1 0.022
epithelial cell proliferation GO:0050673 17 0.022
epiboly GO:0090504 41 0.022
stem cell maintenance GO:0019827 4 0.022
nucleic acid templated transcription GO:0097659 181 0.022
exocrine system development GO:0035272 28 0.021
Fly
cell migration to the midline involved in heart development GO:0003318 12 0.021
i kappab kinase nf kappab signaling GO:0007249 4 0.021
cardiac atrium morphogenesis GO:0003209 2 0.021
peptide transport GO:0015833 1 0.021
organelle organization GO:0006996 227 0.021
Fly
neuronal action potential GO:0019228 18 0.021
regulation of phospholipase activity GO:0010517 2 0.021
Human
positive regulation of cell differentiation GO:0045597 30 0.021
Mouse
regulation of cell projection assembly GO:0060491 4 0.021
melanocyte migration GO:0097324 4 0.021
Zebrafish
mitotic cell cycle GO:0000278 64 0.021
Fly
regulation of neuronal synaptic plasticity GO:0048168 1 0.021
gland morphogenesis GO:0022612 13 0.021
Fly
cellular localization GO:0051641 97 0.021
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.021
response to amphetamine GO:0001975 1 0.021
locomotor rhythm GO:0045475 3 0.021
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.021
Human Mouse Rat
positive regulation of developmental process GO:0051094 50 0.020
Human Zebrafish Mouse
phosphate containing compound metabolic process GO:0006796 108 0.020
Human Zebrafish Mouse Rat Fly

flt1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.119
muscular disease DOID:0080000 0 0.027
musculoskeletal system disease DOID:17 0 0.027
nervous system disease DOID:863 0 0.021