Danio rerio

21 known processes

gadd45bb

growth arrest and DNA-damage-inducible, beta b

(Aliases: gadd45bl,zgc:112453,gadd45b1)

gadd45bb biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
activation of mapkkk activity GO:0000185 1 0.945
Human
p38mapk cascade GO:0038066 1 0.749
Human
regulation of p38mapk cascade GO:1900744 1 0.583
Human
regulation of primary metabolic process GO:0080090 311 0.527
Human Mouse
negative regulation of protein phosphorylation GO:0001933 4 0.408
Mouse
regulation of cellular amine metabolic process GO:0033238 0 0.374
negative regulation of protein kinase activity GO:0006469 4 0.328
Mouse
response to external stimulus GO:0009605 264 0.324
regeneration GO:0031099 91 0.314
response to virus GO:0009615 21 0.310
somite development GO:0061053 96 0.294
response to ketone GO:1901654 1 0.292
synaptic growth at neuromuscular junction GO:0051124 2 0.281
small molecule metabolic process GO:0044281 77 0.265
response to stress GO:0006950 263 0.264
Human
regionalization GO:0003002 274 0.259
neuron projection regeneration GO:0031102 16 0.256
regulation of metabolic process GO:0019222 359 0.253
Human Mouse
positive regulation of biological process GO:0048518 253 0.253
Human Mouse
immune system process GO:0002376 241 0.247
negative regulation of cellular process GO:0048523 283 0.246
Mouse
organic substance biosynthetic process GO:1901576 289 0.244
response to transition metal nanoparticle GO:1990267 28 0.236
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.235
negative regulation of kinase activity GO:0033673 4 0.235
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.223
cellular amine metabolic process GO:0044106 2 0.219
compound eye development GO:0048749 2 0.208
anterior posterior pattern specification GO:0009952 152 0.202
regulation of transcription dna templated GO:0006355 213 0.202
regulation of rna biosynthetic process GO:2001141 213 0.201
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.195
cellular component movement GO:0006928 335 0.189
sensory organ development GO:0007423 393 0.182
response to methylmercury GO:0051597 11 0.176
Zebrafish
cellular ketone metabolic process GO:0042180 11 0.171
regulation of rna metabolic process GO:0051252 224 0.169
eye development GO:0001654 277 0.166
somitogenesis GO:0001756 87 0.163
signal transduction GO:0007165 455 0.162
Human Mouse
paraxial mesoderm development GO:0048339 8 0.155
Zebrafish
amine metabolic process GO:0009308 2 0.151
cellular macromolecule metabolic process GO:0044260 391 0.151
Human Mouse
positive regulation of stress activated protein kinase signaling cascade GO:0070304 3 0.149
Human
vasculature development GO:0001944 278 0.148
cellular protein catabolic process GO:0044257 4 0.144
response to organic substance GO:0010033 153 0.143
Zebrafish
regulation of binding GO:0051098 3 0.133
regulation of biosynthetic process GO:0009889 250 0.133
cognition GO:0050890 1 0.131
regulation of catalytic activity GO:0050790 55 0.130
Human Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.130
cellular biosynthetic process GO:0044249 286 0.129
positive regulation of jnk cascade GO:0046330 3 0.127
Human
response to cadmium ion GO:0046686 14 0.127
Zebrafish
positive regulation of metabolic process GO:0009893 108 0.123
Human Mouse
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.115
developmental growth GO:0048589 166 0.115
camera type eye development GO:0043010 222 0.114
macromolecule modification GO:0043412 111 0.113
Human Mouse
cellular protein modification process GO:0006464 100 0.112
Human Mouse
negative regulation of biological process GO:0048519 304 0.111
Mouse
cellular amino acid metabolic process GO:0006520 7 0.109
heterocycle metabolic process GO:0046483 290 0.108
nitrogen compound metabolic process GO:0006807 319 0.104
protein modification process GO:0036211 100 0.102
Human Mouse
regulation of signal transduction GO:0009966 225 0.102
Human Mouse
ubiquitin dependent protein catabolic process GO:0006511 3 0.102
regulation of nucleic acid templated transcription GO:1903506 213 0.098
biosynthetic process GO:0009058 294 0.097
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.096
sleep GO:0030431 1 0.091
mesoderm development GO:0007498 88 0.091
Zebrafish
tyrosine phosphorylation of stat protein GO:0007260 1 0.090
locomotor rhythm GO:0045475 3 0.090
system process GO:0003008 185 0.090
organic acid metabolic process GO:0006082 31 0.089
embryonic organ development GO:0048568 381 0.088
response to external biotic stimulus GO:0043207 97 0.088
cellular nitrogen compound biosynthetic process GO:0044271 218 0.086
negative regulation of innate immune response GO:0045824 2 0.085
neuron differentiation GO:0030182 353 0.085
sensory organ morphogenesis GO:0090596 200 0.084
cellular response to organic substance GO:0071310 105 0.083
regulation of gene expression GO:0010468 265 0.083
rna metabolic process GO:0016070 219 0.081
response to chemical GO:0042221 320 0.080
Zebrafish
response to other organism GO:0051707 97 0.080
regulation of cellular ketone metabolic process GO:0010565 7 0.079
organic cyclic compound metabolic process GO:1901360 301 0.077
protein metabolic process GO:0019538 183 0.077
Human Mouse
nucleobase containing compound biosynthetic process GO:0034654 205 0.076
wound healing GO:0042060 90 0.075
protein stabilization GO:0050821 2 0.074
digestive tract morphogenesis GO:0048546 231 0.074
single organism metabolic process GO:0044710 217 0.074
Human Mouse
transcription dna templated GO:0006351 181 0.073
transcription from rna polymerase ii promoter GO:0006366 80 0.072
positive regulation of cellular process GO:0048522 201 0.071
Human Mouse
growth GO:0040007 174 0.069
regulation of inflammatory response GO:0050727 2 0.068
regulation of biological quality GO:0065008 263 0.068
regulation of nitrogen compound metabolic process GO:0051171 251 0.068
multi organism process GO:0051704 134 0.068
modification dependent macromolecule catabolic process GO:0043632 3 0.068
organic cyclic compound biosynthetic process GO:1901362 223 0.067
digestive system development GO:0055123 289 0.067
regulation of jak stat cascade GO:0046425 3 0.067
hematopoietic or lymphoid organ development GO:0048534 191 0.066
mesenchyme development GO:0060485 127 0.066
Zebrafish
response to wounding GO:0009611 116 0.065
cellular response to external stimulus GO:0071496 2 0.065
cell projection organization GO:0030030 284 0.064
oxoacid metabolic process GO:0043436 31 0.064
rna biosynthetic process GO:0032774 181 0.064
cellular macromolecule biosynthetic process GO:0034645 224 0.063
cellular component biogenesis GO:0044085 178 0.063
response to biotic stimulus GO:0009607 97 0.063
circadian sleep wake cycle process GO:0022410 2 0.062
cellular nitrogen compound metabolic process GO:0034641 290 0.062
camera type eye morphogenesis GO:0048593 108 0.061
i kappab kinase nf kappab signaling GO:0007249 4 0.061
aging GO:0007568 2 0.060
macromolecule biosynthetic process GO:0009059 227 0.060
cellular protein metabolic process GO:0044267 129 0.059
Human Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.059
negative regulation of gene expression GO:0010629 65 0.058
modification dependent protein catabolic process GO:0019941 3 0.058
negative regulation of macromolecule metabolic process GO:0010605 76 0.057
Mouse
axon development GO:0061564 166 0.057
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.056
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.055
osteoclast differentiation GO:0030316 1 0.055
enzyme linked receptor protein signaling pathway GO:0007167 106 0.055
negative regulation of axon regeneration GO:0048681 4 0.055
cell substrate adhesion GO:0031589 4 0.053
positive regulation of cellular catabolic process GO:0031331 3 0.053
response to axon injury GO:0048678 14 0.053
positive regulation of catabolic process GO:0009896 4 0.052
cell cycle g2 m phase transition GO:0044839 4 0.050
regulation of endodermal cell differentiation GO:1903224 15 0.050
regulation of response to stimulus GO:0048583 269 0.050
Human Mouse
regulation of behavior GO:0050795 24 0.049
nucleocytoplasmic transport GO:0006913 4 0.049
cellular response to stress GO:0033554 62 0.048
Human
regulation of macromolecule metabolic process GO:0060255 317 0.047
Human Mouse
chordate embryonic development GO:0043009 271 0.047
regulation of response to interferon gamma GO:0060330 1 0.045
regulation of cellular metabolic process GO:0031323 320 0.044
Human Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.044
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.044
gene expression GO:0010467 252 0.044
response to metal ion GO:0010038 34 0.043
Zebrafish
tube morphogenesis GO:0035239 349 0.043
response to drug GO:0042493 3 0.042
nucleic acid templated transcription GO:0097659 181 0.042
response to inorganic substance GO:0010035 38 0.042
Zebrafish
axon regeneration GO:0031103 14 0.042
mitochondrion organization GO:0007005 4 0.041
adult behavior GO:0030534 2 0.041
muscle organ development GO:0007517 101 0.041
membrane repolarization GO:0086009 2 0.041
regulation of cellular protein metabolic process GO:0032268 52 0.040
Human Mouse
embryonic hemopoiesis GO:0035162 53 0.040
mesenchymal cell differentiation GO:0048762 87 0.040
regulation of interferon gamma mediated signaling pathway GO:0060334 1 0.040
negative regulation of metabolic process GO:0009892 86 0.040
Mouse
neuron projection development GO:0031175 180 0.040
positive regulation of macromolecule metabolic process GO:0010604 93 0.039
Human Mouse
positive regulation of cellular metabolic process GO:0031325 94 0.039
Human Mouse
cellular response to hormone stimulus GO:0032870 39 0.039
locomotory behavior GO:0007626 34 0.039
protein phosphorylation GO:0006468 47 0.039
Human Mouse
proteasomal protein catabolic process GO:0010498 2 0.039
eye morphogenesis GO:0048592 144 0.039
mechanosensory lateral line system development GO:0048881 49 0.038
regulation of protein binding GO:0043393 3 0.038
heart development GO:0007507 313 0.038
lipid storage GO:0019915 1 0.038
negative regulation of rna metabolic process GO:0051253 48 0.037
regulation of protein localization to nucleus GO:1900180 2 0.037
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.037
cell surface receptor signaling pathway GO:0007166 325 0.036
organonitrogen compound metabolic process GO:1901564 74 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.036
circadian sleep wake cycle sleep GO:0050802 1 0.036
g1 s transition of mitotic cell cycle GO:0000082 1 0.035
endocrine system development GO:0035270 65 0.035
positive regulation of molecular function GO:0044093 33 0.035
Human Mouse
regulation of protein metabolic process GO:0051246 56 0.035
Human Mouse
regulation of metal ion transport GO:0010959 4 0.034
endoderm development GO:0007492 49 0.034
positive regulation of protein metabolic process GO:0051247 23 0.034
Human Mouse
regulation of kinase activity GO:0043549 15 0.034
Human Mouse
neuron development GO:0048666 262 0.034
carboxylic acid metabolic process GO:0019752 22 0.034
cellular response to organic cyclic compound GO:0071407 38 0.033
response to glucocorticoid GO:0051384 1 0.033
regulation of natural killer cell mediated immunity GO:0002715 1 0.033
regulation of stem cell differentiation GO:2000736 4 0.032
response to nutrient GO:0007584 3 0.032
localization of cell GO:0051674 244 0.032
muscle structure development GO:0061061 196 0.032
positive regulation of neural precursor cell proliferation GO:2000179 1 0.032
epithelial cell differentiation GO:0030855 116 0.031
tissue regeneration GO:0042246 74 0.031
phosphate containing compound metabolic process GO:0006796 108 0.031
Human Mouse
primitive hemopoiesis GO:0060215 27 0.031
regulation of purine nucleotide catabolic process GO:0033121 2 0.030
cellular response to growth factor stimulus GO:0071363 39 0.030
cellular response to oxygen levels GO:0071453 1 0.030
regulation of nucleotide catabolic process GO:0030811 2 0.030
regulation of nucleocytoplasmic transport GO:0046822 2 0.030
regulation of cytokine production GO:0001817 3 0.030
cell cycle g1 s phase transition GO:0044843 1 0.029
circadian rhythm GO:0007623 19 0.029
regulation of establishment of protein localization GO:0070201 4 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.029
regulation of cytoplasmic transport GO:1903649 4 0.029
phosphorylation GO:0016310 69 0.029
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.028
positive regulation of cellular component biogenesis GO:0044089 3 0.028
cellular response to chemical stimulus GO:0070887 157 0.028
receptor recycling GO:0001881 4 0.028
regulation of notch signaling pathway GO:0008593 16 0.028
hemopoiesis GO:0030097 183 0.028
negative regulation of nucleic acid templated transcription GO:1903507 45 0.028
posterior lateral line neuromast hair cell development GO:0035677 3 0.027
embryonic organ morphogenesis GO:0048562 274 0.027
gastrulation GO:0007369 208 0.027
epidermal cell fate specification GO:0009957 4 0.027
cellular component assembly GO:0022607 170 0.027
cellular response to decreased oxygen levels GO:0036294 1 0.027
response to amino acid GO:0043200 2 0.027
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.026
regulation of reactive oxygen species metabolic process GO:2000377 2 0.026
nuclear import GO:0051170 3 0.026
regulation of cell cycle GO:0051726 52 0.026
Mouse
lateral line development GO:0048882 66 0.026
cell motility GO:0048870 244 0.025
cell chemotaxis GO:0060326 17 0.025
liver development GO:0001889 96 0.025
gland development GO:0048732 143 0.025
posterior lateral line neuromast development GO:0048919 20 0.025
cellular response to endogenous stimulus GO:0071495 68 0.025
negative regulation of catalytic activity GO:0043086 21 0.025
Mouse
positive regulation of cell cycle GO:0045787 3 0.025
positive regulation of stem cell proliferation GO:2000648 1 0.025
aromatic compound biosynthetic process GO:0019438 217 0.025
regulation of reproductive process GO:2000241 4 0.025
regulation of establishment of protein localization to plasma membrane GO:0090003 1 0.025
regulation of signaling GO:0023051 235 0.024
Human Mouse
regulation of cell substrate adhesion GO:0010810 1 0.024
cellular response to radiation GO:0071478 4 0.024
maintenance of location GO:0051235 4 0.024
blood circulation GO:0008015 87 0.024
cellular response to starvation GO:0009267 1 0.024
taxis GO:0042330 109 0.024
cellular response to extracellular stimulus GO:0031668 2 0.024
positive regulation of transport GO:0051050 2 0.024
negative regulation of neuron projection regeneration GO:0070571 4 0.024
cellular response to hypoxia GO:0071456 1 0.024
regulation of transferase activity GO:0051338 16 0.023
Human Mouse
protein localization to nucleus GO:0034504 3 0.023
negative regulation of biosynthetic process GO:0009890 55 0.023
embryonic viscerocranium morphogenesis GO:0048703 52 0.023
cellular response to molecule of bacterial origin GO:0071219 3 0.023
head development GO:0060322 303 0.023
immune system development GO:0002520 191 0.023
lateral line system development GO:0048925 76 0.022
appendage development GO:0048736 80 0.022
negative regulation of transcription dna templated GO:0045892 45 0.022
negative regulation of signaling GO:0023057 96 0.022
response to dsrna GO:0043331 7 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.022
retina development in camera type eye GO:0060041 146 0.022
sensory system development GO:0048880 76 0.022
digestive tract development GO:0048565 265 0.022
skeletal system development GO:0001501 181 0.022
response to growth factor GO:0070848 39 0.022
response to corticosteroid GO:0031960 1 0.022
regulation of cellular component organization GO:0051128 86 0.021
cellular response to dna damage stimulus GO:0006974 24 0.021
homeostatic process GO:0042592 142 0.021
regulation of dendrite development GO:0050773 3 0.021
circadian sleep wake cycle GO:0042745 2 0.021
negative regulation of cellular metabolic process GO:0031324 77 0.021
Mouse
ectodermal cell fate specification GO:0001715 2 0.021
post embryonic organ development GO:0048569 4 0.021
kidney development GO:0001822 92 0.020
regulation of protein kinase activity GO:0045859 15 0.020
Human Mouse
behavior GO:0007610 74 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
protein kinase b signaling GO:0043491 9 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
positive regulation of neuron death GO:1901216 1 0.020
negative regulation of apoptotic process GO:0043066 55 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
cellular response to lipopolysaccharide GO:0071222 3 0.020
cell matrix adhesion GO:0007160 4 0.020
gtp metabolic process GO:0046039 4 0.020
protein import GO:0017038 3 0.020
single organism nuclear import GO:1902593 3 0.020
posterior lateral line development GO:0048916 38 0.020
positive regulation of cellular protein metabolic process GO:0032270 22 0.020
Human Mouse
positive regulation of epithelial cell proliferation GO:0050679 1 0.020
developmental cell growth GO:0048588 52 0.019
negative regulation of signal transduction GO:0009968 94 0.019
negative regulation of molecular function GO:0044092 23 0.019
Mouse
positive regulation of nucleoside metabolic process GO:0045979 1 0.019
nuclear transport GO:0051169 4 0.019
response to endogenous stimulus GO:0009719 83 0.019
protein import into nucleus GO:0006606 3 0.019
sodium ion transport GO:0006814 24 0.019
regulation of nucleoside metabolic process GO:0009118 2 0.019
establishment of protein localization to plasma membrane GO:0090002 1 0.019
response to alkaloid GO:0043279 2 0.019
negative regulation of defense response GO:0031348 2 0.019
negative regulation of map kinase activity GO:0043407 2 0.019
fertilization GO:0009566 3 0.018
protein targeting to nucleus GO:0044744 3 0.018
determination of left right symmetry GO:0007368 179 0.018
axonogenesis GO:0007409 152 0.018
response to abiotic stimulus GO:0009628 122 0.018
larval development GO:0002164 2 0.018
establishment of protein localization to organelle GO:0072594 4 0.018
microtubule organizing center organization GO:0031023 1 0.018
organic substance catabolic process GO:1901575 28 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
cellular response to oxygen containing compound GO:1901701 20 0.018
g2 m transition of mitotic cell cycle GO:0000086 4 0.018
smooth muscle contraction GO:0006939 2 0.018
ear development GO:0043583 127 0.018
response to mercury ion GO:0046689 1 0.018
myeloid cell differentiation GO:0030099 86 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.017
nuclear export GO:0051168 1 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.017
response to glucose GO:0009749 3 0.017
response to reactive oxygen species GO:0000302 5 0.017
cell projection morphogenesis GO:0048858 244 0.017
negative regulation of cellular protein metabolic process GO:0032269 16 0.017
Mouse
female sex differentiation GO:0046660 4 0.017
organism emergence from protective structure GO:0071684 4 0.017
regulation of molecular function GO:0065009 70 0.017
Human Mouse
guanosine containing compound metabolic process GO:1901068 4 0.017
chemotaxis GO:0006935 104 0.017
antimicrobial humoral response GO:0019730 2 0.017
ion transport GO:0006811 114 0.017
regulation of blood vessel size GO:0050880 2 0.017
neuron neuron synaptic transmission GO:0007270 1 0.017
segmentation GO:0035282 97 0.017
regulation of cell development GO:0060284 100 0.017
mesenchymal cell development GO:0014031 78 0.017
embryonic skeletal system morphogenesis GO:0048704 93 0.017
cell part morphogenesis GO:0032990 246 0.017
intracellular signal transduction GO:0035556 85 0.017
Human Mouse
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.017
regulation of protein transport GO:0051223 3 0.017
regulation of cell motility GO:2000145 46 0.017
peripheral nervous system neuron development GO:0048935 22 0.017
neurological system process GO:0050877 62 0.017
lipid metabolic process GO:0006629 52 0.017
negative regulation of dna replication GO:0008156 2 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.017
response to lipid GO:0033993 60 0.016
cell cycle GO:0007049 93 0.016
Mouse
negative regulation of phosphorus metabolic process GO:0010563 13 0.016
Mouse
peripheral nervous system neuron differentiation GO:0048934 28 0.016
blood vessel development GO:0001568 246 0.016
generation of neurons GO:0048699 385 0.016
glucose import GO:0046323 2 0.016
production of molecular mediator of immune response GO:0002440 2 0.016
negative regulation of phosphate metabolic process GO:0045936 13 0.016
Mouse
regulation of organ growth GO:0046620 3 0.016
inner ear development GO:0048839 126 0.016
immune response GO:0006955 28 0.016
negative regulation of response to cytokine stimulus GO:0060761 2 0.016
positive regulation of developmental process GO:0051094 50 0.016
regulation of neural precursor cell proliferation GO:2000177 3 0.016
regulation of protein phosphorylation GO:0001932 18 0.016
Human Mouse
energy homeostasis GO:0097009 3 0.016
protein localization to plasma membrane GO:0072659 1 0.016
odontogenesis of dentin containing tooth GO:0042475 1 0.016
hair cell differentiation GO:0035315 32 0.016
neuromast hair cell differentiation GO:0048886 12 0.016
positive regulation of leukocyte differentiation GO:1902107 1 0.016
killing of cells in other organism involved in symbiotic interaction GO:0051883 1 0.016
cell death in response to oxidative stress GO:0036473 2 0.016
reactive nitrogen species metabolic process GO:2001057 0 0.016
embryonic skeletal system development GO:0048706 97 0.016
cell migration GO:0016477 237 0.015
circadian behavior GO:0048512 5 0.015
negative regulation of cellular biosynthetic process GO:0031327 55 0.015
female gonad development GO:0008585 4 0.015
positive regulation of nucleotide catabolic process GO:0030813 1 0.015
positive regulation of cell differentiation GO:0045597 30 0.015
gtp catabolic process GO:0006184 2 0.015
retinoid metabolic process GO:0001523 15 0.015
multicellular organism growth GO:0035264 4 0.015
response to oxygen containing compound GO:1901700 55 0.015
negative regulation of jak stat cascade GO:0046426 1 0.015
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.015
regulation of protein ubiquitination GO:0031396 3 0.015
negative regulation of cytokine mediated signaling pathway GO:0001960 2 0.015
cell fate specification GO:0001708 68 0.015
sexual reproduction GO:0019953 36 0.015
startle response GO:0001964 4 0.015
purine nucleoside monophosphate catabolic process GO:0009128 4 0.015
neural crest cell migration GO:0001755 42 0.015
sensory perception of smell GO:0007608 2 0.015
posterior lateral line system development GO:0048915 46 0.015
activation of innate immune response GO:0002218 6 0.015
tyrosine phosphorylation of stat3 protein GO:0042503 1 0.015
striated muscle tissue development GO:0014706 110 0.015
negative regulation of hormone secretion GO:0046888 2 0.014
guanosine containing compound catabolic process GO:1901069 2 0.014
neuromast hair cell development GO:0035675 6 0.014
response to steroid hormone GO:0048545 35 0.014
positive regulation of protein kinase b signaling GO:0051897 1 0.014
centrosome organization GO:0051297 1 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
cellular component disassembly GO:0022411 1 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
cellular response to light stimulus GO:0071482 4 0.014
response to organic cyclic compound GO:0014070 51 0.014
fin regeneration GO:0031101 51 0.014
regulation of response to oxidative stress GO:1902882 2 0.014
metal ion transport GO:0030001 58 0.014
cellular sodium ion homeostasis GO:0006883 1 0.014
muscle cell differentiation GO:0042692 139 0.014
posterior lateral line neuromast hair cell differentiation GO:0048923 8 0.014
cell proliferation GO:0008283 80 0.014
response to bacterium GO:0009617 58 0.014
carbohydrate homeostasis GO:0033500 1 0.014
regulation of axon regeneration GO:0048679 7 0.014
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.014
nerve development GO:0021675 45 0.014
morphogenesis of an epithelium GO:0002009 333 0.014
negative regulation of response to dna damage stimulus GO:2001021 3 0.014
single organism organelle organization GO:1902589 199 0.014
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.014
skin development GO:0043588 54 0.014
regulation of ion transmembrane transporter activity GO:0032412 2 0.014
apoptotic process GO:0006915 116 0.014
Human
response to mechanical stimulus GO:0009612 24 0.014
regulation of glial cell differentiation GO:0045685 4 0.013
extracellular structure organization GO:0043062 27 0.013
regulation of protein modification process GO:0031399 29 0.013
Human Mouse
response to nitrogen compound GO:1901698 19 0.013
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 1 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.013
regulation of ion transmembrane transport GO:0034765 18 0.013
regulation of synapse organization GO:0050807 3 0.013
ectodermal cell differentiation GO:0010668 2 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
multicellular organismal macromolecule metabolic process GO:0044259 2 0.013
response to hormone GO:0009725 48 0.013
regulation of calcium ion transport GO:0051924 2 0.013
negative regulation of protein metabolic process GO:0051248 16 0.013
Mouse
positive regulation of intracellular signal transduction GO:1902533 15 0.013
Human Mouse
epithelial tube morphogenesis GO:0060562 148 0.013
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.013
regulation of membrane potential GO:0042391 23 0.013
interferon gamma mediated signaling pathway GO:0060333 1 0.013
neurotransmitter secretion GO:0007269 2 0.013
regulation of immune system process GO:0002682 34 0.013
response to radiation GO:0009314 51 0.013
negative regulation of response to stimulus GO:0048585 104 0.013
retina layer formation GO:0010842 24 0.013
regulation of stem cell proliferation GO:0072091 2 0.013
cell adhesion mediated by integrin GO:0033627 1 0.013
regulation of protein targeting GO:1903533 2 0.013
fat soluble vitamin metabolic process GO:0006775 4 0.013
regulation of developmental process GO:0050793 247 0.013
positive regulation of cell communication GO:0010647 56 0.012
Human Mouse
biological adhesion GO:0022610 40 0.012
mitochondrial transport GO:0006839 2 0.012
autophagy GO:0006914 4 0.012
heart morphogenesis GO:0003007 156 0.012
protein homooligomerization GO:0051260 3 0.012
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 1 0.012
positive regulation of gtp catabolic process GO:0033126 1 0.012
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.012
monocyte differentiation GO:0030224 2 0.012
regulation of apoptotic process GO:0042981 98 0.012
Human
sodium ion transmembrane transport GO:0035725 21 0.012
regulation of ectodermal cell fate specification GO:0042665 2 0.012
cellular response to nutrient levels GO:0031669 2 0.012
positive regulation of cell division GO:0051781 2 0.012
positive regulation of stress activated mapk cascade GO:0032874 3 0.012
Human
atp catabolic process GO:0006200 4 0.012
regulation of protein catabolic process GO:0042176 1 0.012
endocardial cushion morphogenesis GO:0003203 3 0.012
lens fiber cell morphogenesis GO:0070309 3 0.012
regulation of gtp catabolic process GO:0033124 2 0.012
regulation of cellular protein catabolic process GO:1903362 1 0.012

gadd45bb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.012