Danio rerio

0 known processes

hnf4a

hepatocyte nuclear factor 4, alpha

(Aliases: wu:fb58h09,id:ibd1279,fb58h09)

hnf4a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism localization GO:1902578 225 0.856
Mouse Rat
larval development GO:0002164 2 0.762
Worm
regulation of macromolecule metabolic process GO:0060255 317 0.714
Human Zebrafish Mouse Rat Worm
cellular biosynthetic process GO:0044249 286 0.564
Human Zebrafish Mouse Rat Worm
aromatic compound biosynthetic process GO:0019438 217 0.521
Human Zebrafish Mouse Rat Worm
lipid storage GO:0019915 1 0.452
Worm
organic substance biosynthetic process GO:1901576 289 0.401
Human Zebrafish Mouse Rat Worm
locomotion GO:0040011 313 0.390
Worm
single organism metabolic process GO:0044710 217 0.384
Human Mouse Rat Worm Fly
endocrine pancreas development GO:0031018 27 0.371
positive regulation of cellular process GO:0048522 201 0.361
Human Zebrafish Mouse Rat Worm
regulation of protein complex assembly GO:0043254 3 0.317
maintenance of location GO:0051235 4 0.292
Worm
positive regulation of protein complex assembly GO:0031334 2 0.290
endocrine system development GO:0035270 65 0.287
establishment of localization GO:0051234 244 0.282
Mouse Rat Worm
cellular aromatic compound metabolic process GO:0006725 295 0.267
Human Zebrafish Mouse Rat Worm
regulation of cellular metabolic process GO:0031323 320 0.266
Human Zebrafish Mouse Rat Worm
organic substance transport GO:0071702 58 0.265
Mouse Rat
cellular response to organic cyclic compound GO:0071407 38 0.264
cellular nitrogen compound biosynthetic process GO:0044271 218 0.254
Human Zebrafish Mouse Rat Worm
hormone secretion GO:0046879 2 0.245
Mouse
aging GO:0007568 2 0.245
Worm
long chain fatty acid transport GO:0015909 1 0.236
cell morphogenesis GO:0000902 289 0.235
cellular component movement GO:0006928 335 0.231
regulation of rna biosynthetic process GO:2001141 213 0.226
Human Zebrafish Mouse Rat Worm
organic anion transport GO:0015711 15 0.224
cellular localization GO:0051641 97 0.221
Mouse Rat
homeostatic process GO:0042592 142 0.218
Human Mouse
digestive system development GO:0055123 289 0.217
Mouse
cell projection organization GO:0030030 284 0.215
Rat
regulation of gene expression GO:0010468 265 0.212
Human Zebrafish Mouse Rat Worm
digestive tract development GO:0048565 265 0.212
Mouse
brain development GO:0007420 293 0.208
intestinal absorption GO:0050892 2 0.201
pancreas development GO:0031016 84 0.200
urogenital system development GO:0001655 97 0.193
organic cyclic compound metabolic process GO:1901360 301 0.188
Human Zebrafish Mouse Rat Worm
transcription dna templated GO:0006351 181 0.184
Human Zebrafish Mouse Rat Worm
generation of neurons GO:0048699 385 0.179
localization of cell GO:0051674 244 0.178
positive regulation of cellular component biogenesis GO:0044089 3 0.177
response to other organism GO:0051707 97 0.174
positive regulation of biological process GO:0048518 253 0.168
Human Zebrafish Mouse Rat Worm
carboxylic acid catabolic process GO:0046395 3 0.165
regulation of nitrogen compound metabolic process GO:0051171 251 0.159
Human Zebrafish Mouse Rat Worm
regulation of transcription dna templated GO:0006355 213 0.157
Human Zebrafish Mouse Rat Worm
regulation of macromolecule biosynthetic process GO:0010556 225 0.155
Human Zebrafish Mouse Rat Worm
type b pancreatic cell development GO:0003323 4 0.154
regulation of cell communication GO:0010646 232 0.153
Mouse Rat
regulation of biosynthetic process GO:0009889 250 0.151
Human Zebrafish Mouse Rat Worm
sensory organ development GO:0007423 393 0.147
neuron projection development GO:0031175 180 0.147
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.146
Human Zebrafish Mouse Rat Worm
transport GO:0006810 220 0.143
Mouse Rat Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.141
Human Zebrafish Mouse Rat Worm
lipid metabolic process GO:0006629 52 0.140
Human Mouse Rat Worm Fly
central nervous system development GO:0007417 387 0.140
nucleobase containing compound biosynthetic process GO:0034654 205 0.139
Human Zebrafish Mouse Rat Worm
response to organic substance GO:0010033 153 0.135
Zebrafish Mouse Rat
response to carbohydrate GO:0009743 3 0.133
Mouse Rat
response to chemical GO:0042221 320 0.129
Human Zebrafish Mouse Rat
segmentation GO:0035282 97 0.129
embryonic digestive tract morphogenesis GO:0048557 3 0.128
response to drug GO:0042493 3 0.124
Rat
regulation of developmental growth GO:0048638 38 0.123
cell part morphogenesis GO:0032990 246 0.123
positive regulation of rna biosynthetic process GO:1902680 57 0.122
Human Zebrafish Mouse Rat Worm
regulation of metabolic process GO:0019222 359 0.121
Human Zebrafish Mouse Rat Worm
regulation of multicellular organismal development GO:2000026 223 0.119
Mouse
regulation of primary metabolic process GO:0080090 311 0.118
Human Zebrafish Mouse Rat Worm
response to nutrient GO:0007584 3 0.118
cellular macromolecule biosynthetic process GO:0034645 224 0.116
Human Zebrafish Mouse Rat Worm
neuron differentiation GO:0030182 353 0.114
kidney development GO:0001822 92 0.113
response to vitamin GO:0033273 3 0.113
positive regulation of gene expression GO:0010628 71 0.113
Human Zebrafish Mouse Rat Worm
positive regulation of transport GO:0051050 2 0.111
gastrulation GO:0007369 208 0.109
Mouse
ameboidal type cell migration GO:0001667 143 0.107
cellular nitrogen compound metabolic process GO:0034641 290 0.105
Human Zebrafish Mouse Rat Worm
nitrogen compound metabolic process GO:0006807 319 0.105
Human Zebrafish Mouse Rat Worm
embryonic digestive tract development GO:0048566 4 0.105
epithelial cell differentiation GO:0030855 116 0.102
Zebrafish
lateral line system development GO:0048925 76 0.100
positive regulation of cell adhesion GO:0045785 1 0.097
system process GO:0003008 185 0.097
macromolecular complex assembly GO:0065003 35 0.095
regulation of transport GO:0051049 45 0.095
Mouse Rat
cellular response to endogenous stimulus GO:0071495 68 0.094
heterocycle biosynthetic process GO:0018130 215 0.092
Human Zebrafish Mouse Rat Worm
cellular lipid metabolic process GO:0044255 36 0.090
Rat Worm Fly
embryonic eye morphogenesis GO:0048048 30 0.088
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.087
Human Zebrafish Mouse Rat Worm
lipid localization GO:0010876 11 0.087
Worm
hematopoietic or lymphoid organ development GO:0048534 191 0.086
biosynthetic process GO:0009058 294 0.086
Human Zebrafish Mouse Rat Worm
peptide transport GO:0015833 1 0.085
Mouse
cellular response to starvation GO:0009267 1 0.085
cellular carbohydrate metabolic process GO:0044262 4 0.084
Rat
negative regulation of signal transduction GO:0009968 94 0.082
Rat
establishment of localization in cell GO:0051649 77 0.082
Mouse Rat
foregut morphogenesis GO:0007440 4 0.082
toxin metabolic process GO:0009404 1 0.081
nucleic acid metabolic process GO:0090304 244 0.079
Human Zebrafish Mouse Rat Worm
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.079
Human Zebrafish Mouse Rat Worm
positive regulation of cellular biosynthetic process GO:0031328 68 0.079
Human Zebrafish Mouse Rat Worm
somitogenesis GO:0001756 87 0.078
negative regulation of response to stimulus GO:0048585 104 0.077
Rat
cell death GO:0008219 121 0.077
cellular response to extracellular stimulus GO:0031668 2 0.077
liver development GO:0001889 96 0.077
fat soluble vitamin metabolic process GO:0006775 4 0.076
developmental programmed cell death GO:0010623 4 0.076
head development GO:0060322 303 0.076
positive regulation of metabolic process GO:0009893 108 0.074
Human Zebrafish Mouse Rat Worm
regulation of growth GO:0040008 42 0.073
Human
gene expression GO:0010467 252 0.073
Human Zebrafish Mouse Rat Worm
macromolecule localization GO:0033036 54 0.072
Rat Worm
nucleic acid templated transcription GO:0097659 181 0.072
Human Zebrafish Mouse Rat Worm
cellular response to nutrient levels GO:0031669 2 0.070
cellular component morphogenesis GO:0032989 336 0.070
response to monosaccharide GO:0034284 3 0.069
Mouse Rat
regulation of localization GO:0032879 104 0.068
Mouse Rat
oxoacid metabolic process GO:0043436 31 0.068
Human Rat Worm
nucleobase containing compound metabolic process GO:0006139 274 0.067
Human Zebrafish Mouse Rat Worm
neural tube patterning GO:0021532 33 0.065
regulation of establishment of protein localization GO:0070201 4 0.065
Rat
blood vessel development GO:0001568 246 0.065
macromolecule biosynthetic process GO:0009059 227 0.065
Human Zebrafish Mouse Rat Worm
axonogenesis GO:0007409 152 0.065
regulation of biological quality GO:0065008 263 0.064
Human Mouse Worm
small molecule metabolic process GO:0044281 77 0.063
Human Rat Worm
lipid oxidation GO:0034440 1 0.063
Fly
death GO:0016265 121 0.062
protein metabolic process GO:0019538 183 0.062
Rat
hormone transport GO:0009914 2 0.061
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.060
female sex differentiation GO:0046660 4 0.060
somite development GO:0061053 96 0.060
regulation of rna metabolic process GO:0051252 224 0.059
Human Zebrafish Mouse Rat Worm
cell projection morphogenesis GO:0048858 244 0.059
cellular response to organic substance GO:0071310 105 0.059
axon development GO:0061564 166 0.057
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.056
Zebrafish
cell motility GO:0048870 244 0.056
response to glucose GO:0009749 3 0.055
Mouse Rat
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.055
positive regulation of signaling GO:0023056 56 0.054
Rat
regulation of wnt signaling pathway involved in digestive tract morphogenesis GO:2000056 2 0.054
developmental growth GO:0048589 166 0.054
regulation of cell differentiation GO:0045595 142 0.054
renal tubule morphogenesis GO:0061333 1 0.053
neuron projection morphogenesis GO:0048812 161 0.053
regulation of fatty acid metabolic process GO:0019217 1 0.053
Rat Worm
cellular response to estrogen stimulus GO:0071391 24 0.052
negative regulation of rna metabolic process GO:0051253 48 0.051
Zebrafish
single organism transport GO:0044765 206 0.051
Mouse Rat
response to organic cyclic compound GO:0014070 51 0.050
Rat
regulation of response to stimulus GO:0048583 269 0.050
Rat
regulation of organ growth GO:0046620 3 0.050
reproduction GO:0000003 40 0.050
Worm
regulation of hormone secretion GO:0046883 2 0.050
Mouse
lipid biosynthetic process GO:0008610 22 0.050
Rat
carboxylic acid transport GO:0046942 8 0.048
positive regulation of developmental process GO:0051094 50 0.048
cell migration GO:0016477 237 0.048
hormone biosynthetic process GO:0042446 3 0.047
anion transport GO:0006820 38 0.047
regulation of tube size GO:0035150 2 0.047
apoptotic process involved in morphogenesis GO:0060561 2 0.047
mycotoxin metabolic process GO:0043385 1 0.046
cytoskeleton organization GO:0007010 96 0.046
cellular component biogenesis GO:0044085 178 0.045
Rat
organic heteropentacyclic compound metabolic process GO:1901376 1 0.045
regulation of anatomical structure size GO:0090066 33 0.045
multicellular organism growth GO:0035264 4 0.044
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.044
Rat
nephron morphogenesis GO:0072028 2 0.044
cellular response to chemical stimulus GO:0070887 157 0.044
Human
response to hexose GO:0009746 3 0.044
Mouse Rat
acylglycerol homeostasis GO:0055090 2 0.044
Mouse
immune system process GO:0002376 241 0.043
cellular macromolecular complex assembly GO:0034622 24 0.043
regulation of signaling GO:0023051 235 0.042
Mouse Rat
stem cell development GO:0048864 82 0.042
signal transduction GO:0007165 455 0.042
Zebrafish Mouse Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.041
Human Zebrafish Mouse Rat Worm
single organism membrane fusion GO:0044801 2 0.041
long chain fatty acid metabolic process GO:0001676 1 0.041
cellular protein catabolic process GO:0044257 4 0.041
sensory organ morphogenesis GO:0090596 200 0.041
response to stress GO:0006950 263 0.040
Human
growth GO:0040007 174 0.040
Human
organic cyclic compound biosynthetic process GO:1901362 223 0.040
Human Zebrafish Mouse Rat Worm
apoptotic process involved in development GO:1902742 2 0.040
regulation of cell motility GO:2000145 46 0.039
female gonad development GO:0008585 4 0.039
regulation of stem cell differentiation GO:2000736 4 0.039
protein localization GO:0008104 40 0.039
Rat
regulation of cell migration GO:0030334 40 0.038
oxidation reduction process GO:0055114 41 0.038
Fly
regulation of protein transport GO:0051223 3 0.038
Rat
organic acid metabolic process GO:0006082 31 0.038
Human Rat Worm
protein polymerization GO:0051258 4 0.038
response to external biotic stimulus GO:0043207 97 0.038
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.038
Rat
stem cell maintenance GO:0019827 4 0.037
carboxylic acid metabolic process GO:0019752 22 0.037
Human Rat Worm
mesenchymal cell differentiation GO:0048762 87 0.037
negative regulation of gene expression GO:0010629 65 0.036
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 80 0.036
Human Zebrafish Mouse Rat Worm
negative regulation of cellular biosynthetic process GO:0031327 55 0.036
Zebrafish
microtubule based process GO:0007017 60 0.036
cellular ketone metabolic process GO:0042180 11 0.036
Rat Worm
hepatocyte proliferation GO:0072574 2 0.035
response to biotic stimulus GO:0009607 97 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.035
Zebrafish
regulation of intracellular protein transport GO:0033157 3 0.035
Rat
regulation of signal transduction GO:0009966 225 0.035
Rat
eye morphogenesis GO:0048592 144 0.035
organonitrogen compound metabolic process GO:1901564 74 0.034
Human
regulation of blood vessel size GO:0050880 2 0.034
stem cell differentiation GO:0048863 117 0.034
regulation of cell development GO:0060284 100 0.034
morphogenesis of an epithelium GO:0002009 333 0.034
peptide metabolic process GO:0006518 1 0.034
negative regulation of stem cell differentiation GO:2000737 2 0.034
renal system development GO:0072001 94 0.034
catechol containing compound metabolic process GO:0009712 2 0.033
tube closure GO:0060606 1 0.033
regulation of reproductive process GO:2000241 4 0.033
neuron development GO:0048666 262 0.033
rna metabolic process GO:0016070 219 0.033
Human Zebrafish Mouse Rat Worm
epithelial tube morphogenesis GO:0060562 148 0.033
positive regulation of cytoskeleton organization GO:0051495 3 0.033
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.033
defense response to other organism GO:0098542 33 0.033
regulation of catalytic activity GO:0050790 55 0.032
Rat
programmed cell death GO:0012501 119 0.032
protein complex assembly GO:0006461 30 0.032
gtp catabolic process GO:0006184 2 0.032
neuron migration GO:0001764 22 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 59 0.032
Human Zebrafish Mouse Rat Worm
response to xenobiotic stimulus GO:0009410 45 0.031
Human
immune system development GO:0002520 191 0.031
digestive tract morphogenesis GO:0048546 231 0.031
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.031
Human Zebrafish Mouse Rat Worm
guanosine containing compound metabolic process GO:1901068 4 0.030
wnt signaling pathway involved in digestive tract morphogenesis GO:0044333 4 0.030
auditory receptor cell differentiation GO:0042491 15 0.030
forebrain development GO:0030900 96 0.030
development of primary female sexual characteristics GO:0046545 4 0.030
organelle organization GO:0006996 227 0.030
gland development GO:0048732 143 0.030
fatty acid biosynthetic process GO:0006633 4 0.030
Rat
positive regulation of macromolecule metabolic process GO:0010604 93 0.030
Human Zebrafish Mouse Rat Worm
tube morphogenesis GO:0035239 349 0.030
Mouse
regulation of hemostasis GO:1900046 1 0.030
negative regulation of biological process GO:0048519 304 0.029
Human Zebrafish Rat
cellular macromolecule metabolic process GO:0044260 391 0.029
Human Zebrafish Mouse Rat Worm
negative regulation of cellular metabolic process GO:0031324 77 0.029
Zebrafish Rat
small molecule biosynthetic process GO:0044283 16 0.029
Rat
embryonic heart tube morphogenesis GO:0003143 108 0.029
regulation of gtpase activity GO:0043087 2 0.029
epidermis development GO:0008544 48 0.028
lipid homeostasis GO:0055088 3 0.028
Human Mouse
guanosine containing compound catabolic process GO:1901069 2 0.028
epiboly GO:0090504 41 0.028
regulation of carbohydrate metabolic process GO:0006109 4 0.028
Rat
sexual reproduction GO:0019953 36 0.028
positive regulation of transcription dna templated GO:0045893 57 0.028
Human Zebrafish Mouse Rat Worm
multi organism process GO:0051704 134 0.027
fatty acid transport GO:0015908 1 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
Mouse
cellular amino acid metabolic process GO:0006520 7 0.026
Human
embryonic camera type eye development GO:0031076 29 0.026
optic placode formation involved in camera type eye formation GO:0046619 3 0.026
embryonic pectoral fin morphogenesis GO:0035118 24 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
response to external stimulus GO:0009605 264 0.025
aflatoxin b1 metabolic process GO:0043390 1 0.025
positive regulation of biosynthetic process GO:0009891 68 0.025
Human Zebrafish Mouse Rat Worm
skin development GO:0043588 54 0.025
regionalization GO:0003002 274 0.024
neurotransmitter transport GO:0006836 2 0.024
dicarboxylic acid transport GO:0006835 1 0.024
hepatocyte differentiation GO:0070365 1 0.023
embryonic foregut morphogenesis GO:0048617 1 0.023
cellular response to external stimulus GO:0071496 2 0.023
cell cell signaling GO:0007267 52 0.023
Mouse
response to hormone GO:0009725 48 0.023
positive regulation of epithelial cell differentiation GO:0030858 2 0.023
angiogenesis GO:0001525 158 0.023
negative regulation of metabolic process GO:0009892 86 0.023
Zebrafish Rat
pronephric nephron tubule development GO:0039020 2 0.023
negative regulation of apoptotic process GO:0043066 55 0.023
cell proliferation GO:0008283 80 0.023
Human Rat
mitochondrion organization GO:0007005 4 0.022
response to oxygen containing compound GO:1901700 55 0.022
Zebrafish Mouse Rat
negative regulation of protein localization to nucleus GO:1900181 2 0.022
Rat
rna biosynthetic process GO:0032774 181 0.022
Human Zebrafish Mouse Rat Worm
golgi vesicle transport GO:0048193 3 0.022
positive regulation of neuron migration GO:2001224 2 0.022
enteroendocrine cell differentiation GO:0035883 9 0.022
phagocytosis GO:0006909 3 0.022
embryonic organ development GO:0048568 381 0.022
response to lipid GO:0033993 60 0.022
Zebrafish
rhombomere 5 morphogenesis GO:0021664 1 0.022
regulation of neuron migration GO:2001222 2 0.021
blood vessel morphogenesis GO:0048514 216 0.021
hepaticobiliary system development GO:0061008 98 0.021
cellular component assembly GO:0022607 170 0.021
Rat
digestion GO:0007586 11 0.021
regulation of nervous system development GO:0051960 90 0.021
protein complex biogenesis GO:0070271 30 0.021
cellular response to hormone stimulus GO:0032870 39 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
fatty acid metabolic process GO:0006631 5 0.020
Rat Worm
cell surface receptor signaling pathway GO:0007166 325 0.020
Mouse
apoptotic process GO:0006915 116 0.020
negative regulation of mitosis GO:0045839 3 0.020
positive regulation of gtpase activity GO:0043547 1 0.020
plasma membrane repair GO:0001778 2 0.020
vasculature development GO:0001944 278 0.020
Zebrafish
cellular amide metabolic process GO:0043603 4 0.020
mesenchyme development GO:0060485 127 0.020
optic placode formation GO:0001743 4 0.020
negative regulation of cellular process GO:0048523 283 0.020
Human Zebrafish Rat
multicellular organismal reproductive process GO:0048609 35 0.019
embryonic pattern specification GO:0009880 44 0.019
membrane organization GO:0061024 21 0.019
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.019
organelle fusion GO:0048284 3 0.019
negative regulation of rna biosynthetic process GO:1902679 45 0.019
Zebrafish
cellular response to lipid GO:0071396 39 0.019
mesenchymal cell development GO:0014031 78 0.018
defense response to bacterium GO:0042742 22 0.018
actin filament based process GO:0030029 64 0.018
protein complex subunit organization GO:0071822 46 0.018
response to estrogen GO:0043627 27 0.018
otolith morphogenesis GO:0032474 8 0.018
epithelial cell development GO:0002064 42 0.018
regulation of purine nucleotide catabolic process GO:0033121 2 0.018
astrocyte differentiation GO:0048708 1 0.018
cyclic nucleotide metabolic process GO:0009187 18 0.018
positive regulation of nucleoside metabolic process GO:0045979 1 0.018
regulation of nucleocytoplasmic transport GO:0046822 2 0.018
Rat
gall bladder development GO:0061010 1 0.018
cellular response to xenobiotic stimulus GO:0071466 35 0.018
Human
lymphatic endothelial cell differentiation GO:0060836 1 0.018
Zebrafish
regulation of protein polymerization GO:0032271 2 0.018
positive regulation of catabolic process GO:0009896 4 0.018
nephron epithelium morphogenesis GO:0072088 1 0.017
regulation of cellular ketone metabolic process GO:0010565 7 0.017
Rat Worm
negative regulation of cell development GO:0010721 26 0.017
positive regulation of cellular catabolic process GO:0031331 3 0.017
amide transport GO:0042886 12 0.017
Mouse
single organism organelle organization GO:1902589 199 0.017
positive regulation of protein polymerization GO:0032273 2 0.017
negative regulation of multicellular organismal process GO:0051241 69 0.017
negative regulation of biosynthetic process GO:0009890 55 0.017
Zebrafish
regulation of cytokine production GO:0001817 3 0.017
monocarboxylic acid transport GO:0015718 5 0.017
embryonic hemopoiesis GO:0035162 53 0.017
embryo development ending in birth or egg hatching GO:0009792 271 0.016
Worm
organ formation GO:0048645 17 0.016
regulation of nucleoside metabolic process GO:0009118 2 0.016
embryonic appendage morphogenesis GO:0035113 30 0.016
neural crest cell differentiation GO:0014033 72 0.016
regulation of cellular amine metabolic process GO:0033238 0 0.016
adherens junction organization GO:0034332 4 0.016
skeletal system development GO:0001501 181 0.016
negative regulation of gastrulation GO:2000542 11 0.016
regulation of cellular protein metabolic process GO:0032268 52 0.016
Rat
digestive system process GO:0022600 9 0.016
zymogen activation GO:0031638 3 0.016
regulation of gtp catabolic process GO:0033124 2 0.016
protein localization to plasma membrane GO:0072659 1 0.016
secondary metabolic process GO:0019748 3 0.016
single organism intracellular transport GO:1902582 25 0.016
Rat
negative regulation of cell migration GO:0030336 17 0.016
morphogenesis of an epithelial sheet GO:0002011 49 0.016
regulation of multicellular organism growth GO:0040014 4 0.016
positive regulation of secretion GO:0051047 1 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.015
Zebrafish
response to abiotic stimulus GO:0009628 122 0.015
negative regulation of reproductive process GO:2000242 3 0.015
reproductive process GO:0022414 40 0.015
Mouse
cilium morphogenesis GO:0060271 85 0.015
type b pancreatic cell differentiation GO:0003309 8 0.015
gastrulation with mouth forming second GO:0001702 44 0.015
catabolic process GO:0009056 32 0.015
Fly
intrinsic apoptotic signaling pathway GO:0097193 20 0.015
common bile duct development GO:0061009 13 0.014
positive regulation of cellular metabolic process GO:0031325 94 0.014
Human Zebrafish Mouse Rat Worm
cellular protein metabolic process GO:0044267 129 0.014
Rat
endodermal digestive tract morphogenesis GO:0061031 2 0.014
retina development in camera type eye GO:0060041 146 0.014
cell differentiation in hindbrain GO:0021533 5 0.014
single organism biosynthetic process GO:0044711 71 0.014
Rat
heterocycle metabolic process GO:0046483 290 0.014
Human Zebrafish Mouse Rat Worm
modification dependent macromolecule catabolic process GO:0043632 3 0.014
negative regulation of mesodermal cell fate specification GO:0042662 3 0.014
ion transport GO:0006811 114 0.014
positive regulation of cell communication GO:0010647 56 0.014
Rat
metal ion transport GO:0030001 58 0.014
negative regulation of nucleic acid templated transcription GO:1903507 45 0.014
Zebrafish
multicellular organismal response to stress GO:0033555 2 0.014
intracellular transport GO:0046907 32 0.014
Rat
regulation of locomotion GO:0040012 55 0.014
regulation of intracellular signal transduction GO:1902531 57 0.014
Rat
taxis GO:0042330 109 0.014
regulation of phosphate metabolic process GO:0019220 43 0.014
Rat
embryonic camera type eye formation GO:0060900 10 0.014
embryonic organ morphogenesis GO:0048562 274 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.013
mitochondrial transport GO:0006839 2 0.013
post anal tail morphogenesis GO:0036342 19 0.013
membrane fusion GO:0061025 2 0.013
chordate embryonic development GO:0043009 271 0.013
steroid biosynthetic process GO:0006694 5 0.013
regulation of hydrolase activity GO:0051336 28 0.013
aflatoxin metabolic process GO:0046222 1 0.013
embryonic camera type eye morphogenesis GO:0048596 19 0.013
lipid catabolic process GO:0016042 4 0.013
Fly
sensory system development GO:0048880 76 0.013
alcohol biosynthetic process GO:0046165 2 0.013
cerebellar cortex formation GO:0021697 5 0.013
regulation of cell death GO:0010941 103 0.013
positive regulation of nucleic acid templated transcription GO:1903508 57 0.013
Human Zebrafish Mouse Rat Worm
cellular response to stress GO:0033554 62 0.013
ion homeostasis GO:0050801 41 0.013
Mouse
dna templated transcription initiation GO:0006352 1 0.013
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.013
renal system process involved in regulation of systemic arterial blood pressure GO:0003071 1 0.012
endothelial cell differentiation GO:0045446 20 0.012
Zebrafish
ventral spinal cord development GO:0021517 35 0.012
positive regulation of rna metabolic process GO:0051254 59 0.012
Human Zebrafish Mouse Rat Worm
negative regulation of wnt signaling pathway GO:0030178 30 0.012
regulation of cellular component organization GO:0051128 86 0.012
Human Rat
regulation of gastrulation GO:0010470 24 0.012
Mouse
regulation of cytoplasmic transport GO:1903649 4 0.012
Rat
sensory perception of chemical stimulus GO:0007606 3 0.012
positive regulation of response to stimulus GO:0048584 80 0.012
Rat
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
hair cell differentiation GO:0035315 32 0.012
biological adhesion GO:0022610 40 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
Human Zebrafish Mouse Rat Worm
eye photoreceptor cell differentiation GO:0001754 45 0.012
regulation of apoptotic process GO:0042981 98 0.012
chemosensory behavior GO:0007635 1 0.012
photoreceptor cell differentiation GO:0046530 55 0.012
vitamin biosynthetic process GO:0009110 2 0.012
central nervous system neuron differentiation GO:0021953 74 0.012
ear morphogenesis GO:0042471 64 0.012
auditory receptor cell morphogenesis GO:0002093 4 0.011
triglyceride homeostasis GO:0070328 2 0.011
Mouse
multicellular organism reproduction GO:0032504 35 0.011
cell migration involved in gastrulation GO:0042074 79 0.011
epidermal cell differentiation GO:0009913 36 0.011
response to endogenous stimulus GO:0009719 83 0.011
Rat
cerebellar granule cell differentiation GO:0021707 3 0.011
morphogenesis of embryonic epithelium GO:0016331 30 0.011
chemical homeostasis GO:0048878 49 0.011
Human Mouse
cerebellar granular layer formation GO:0021684 3 0.011
ectoderm development GO:0007398 9 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.011
Zebrafish
cellular response to oxygen levels GO:0071453 1 0.011
positive regulation of cellular component organization GO:0051130 13 0.011
regulation of microtubule cytoskeleton organization GO:0070507 3 0.011
negative regulation of mapk cascade GO:0043409 4 0.011
lateral line development GO:0048882 66 0.011
inner ear receptor stereocilium organization GO:0060122 8 0.011
regulation of epithelial cell proliferation GO:0050678 3 0.011
post embryonic foregut morphogenesis GO:0048618 3 0.011
actin filament polymerization GO:0030041 2 0.011
fat soluble vitamin biosynthetic process GO:0042362 2 0.010
carbohydrate homeostasis GO:0033500 1 0.010
Mouse
hemopoiesis GO:0030097 183 0.010
negative regulation of kinase activity GO:0033673 4 0.010
neurotransmitter secretion GO:0007269 2 0.010
proteolysis GO:0006508 38 0.010
organic cyclic compound catabolic process GO:1901361 15 0.010
negative regulation of nuclear division GO:0051784 3 0.010

hnf4a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
urinary system cancer DOID:3996 0 0.355
cancer DOID:162 0 0.355
disease of cellular proliferation DOID:14566 0 0.355
organ system cancer DOID:0050686 0 0.355
maturity onset diabetes of the young DOID:0050524 0 0.267
Human
diabetes mellitus DOID:9351 0 0.094
Human
type 2 diabetes mellitus DOID:9352 0 0.094
Human
disease of metabolism DOID:0014667 0 0.094
Human
carbohydrate metabolism disease DOID:0050013 0 0.094
Human
glucose metabolism disease DOID:4194 0 0.094
Human
acquired metabolic disease DOID:0060158 0 0.094
Human
disease of anatomical entity DOID:7 0 0.012