IMP
Process View
aflatoxin metabolic process
The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "aflatoxin metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| serpinf2 | serine (or cysteine) peptidase inhibitor, clade F, member 2 | 0.143 | ||
| upp2 | uridine phosphorylase 2 | 0.113 | ||
| cyp51 | cytochrome P450, family 51 | 0.064 | ||
| nr5a5 | nuclear receptor subfamily 5, group A, member 5 | 0.054 | ||
| proc | protein C (inactivator of coagulation factors Va and VIIIa) | 0.052 | ||
| sult1st3 | sulfotransferase family 1, cytosolic sulfotransferase 3 | 0.050 | ||
| ahsg | alpha-2-HS-glycoprotein | 0.049 | ||
| lipc | lipase, hepatic | 0.042 | ||
| abp1 | amiloride binding protein 1 (amine oxidase (copper-containing)) | 0.037 | ||
| slc34a2a | solute carrier family 34 (sodium phosphate), member 2a | 0.035 | ||
| mep1a.1 | meprin A, alpha.1 | 0.033 | ||
| cyp2aa1 | cytochrome P450, family 2, subfamily AA, polypeptide 1 | 0.030 | ||
| chia.2 | chitinase, acidic.2 | 0.030 | ||
| cyp4t8 | cytochrome P450, family 4, subfamily T, polypeptide 8 | 0.029 | ||
| shbg | sex hormone binding globulin | 0.028 | ||
| igfbp1b | insulin-like growth factor binding protein 1b | 0.027 | ||
| LOC569770 | cytochrome c oxidase subunit 8B, mitochondrial-like | 0.024 | ||
| srd5a2a | steroid-5-alpha-reductase, alpha polypeptide 2a | 0.023 | ||
| map9 | microtubule-associated protein 9 | 0.023 | ||
| angptl3 | angiopoietin-like 3 | 0.023 | ||
| spata18 | spermatogenesis associated 18 | 0.022 | ||
| cyp24a1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.022 | ||
| shmt2 | serine hydroxymethyltransferase 2 (mitochondrial) | 0.022 | ||
| ahr1a | aryl hydrocarbon receptor 1a | 0.021 | ||
| irgq1 | immunity-related GTPase family, q1 | 0.021 | ||
| agmo | alkylglycerol monooxygenase | 0.020 | ||
| zgc:113516 | zgc:113516 | 0.020 | ||
| zgc:64076 | zgc:64076 | 0.019 | ||
| zgc:56326 | zgc:56326 | 0.018 | ||
| cyp2k18 | cytochrome P450, family 2, subfamily K, polypeptide 18 | 0.017 | Zebrafish | |
| pklr | pyruvate kinase, liver and RBC | 0.017 | ||
| zgc:92406 | zgc:92406 | 0.017 | ||
| cpne3 | copine III | 0.017 | ||
| fabp10a | fatty acid binding protein 10a, liver basic | 0.017 | ||
| hbl3 | hexose-binding lectin 3 | 0.017 | ||
| star | steroidogenic acute regulatory protein | 0.017 | ||
| ca9 | carbonic anhydrase IX | 0.016 | ||
| hsd17b3 | hydroxysteroid (17-beta) dehydrogenase 3 | 0.016 | ||
| slc8a4b | solute carrier family 8 (sodium/calcium exchanger), member 4b | 0.016 | ||
| acad11 | acyl-Coenzyme A dehydrogenase family, member 11 | 0.016 | ||
| zgc:112432 | zgc:112432 | 0.015 | ||
| sat2 | spermidine/spermine N1-acetyltransferase family member 2 | 0.015 | ||
| bcdo2l | beta-carotene 15, 15-dioxygenase 2, like | 0.014 | ||
| cx32.3 | connexin 32.3 | 0.014 | ||
| zgc:66484 | zgc:66484 | 0.014 | ||
| mospd2 | motile sperm domain containing 2 | 0.014 | ||
| oclna | occludin a | 0.014 | ||
| zgc:56622 | zgc:56622 | 0.014 | ||
| hprt1 | hypoxanthine phosphoribosyltransferase 1 | 0.014 | ||
| hpx | hemopexin | 0.014 | ||
| zgc:198195 | zgc:198195 | 0.013 | ||
| zgc:153921 | zgc:153921 | 0.013 | ||
| hnf4a | hepatocyte nuclear factor 4, alpha | 0.013 | ||
| hsd17b1 | hydroxysteroid (17-beta) dehydrogenase 1 | 0.013 | ||
| tbxas1 | thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A) | 0.013 | ||
| vtg4 | vitellogenin 4 | 0.013 | ||
| cyp2p6 | cytochrome P450, family 2, subfamily P, polypeptide 6 | 0.012 | Zebrafish | |
| agt | angiotensinogen | 0.012 | ||
| aqp12 | aquaporin 12 | 0.012 | ||
| dio1 | deiodinase, iodothyronine, type I | 0.012 | ||
| zgc:63774 | zgc:63774 | 0.012 | ||
| ldhbb | lactate dehydrogenase Bb | 0.012 | ||
| hprt1l | hypoxanthine phosphoribosyltransferase 1, like | 0.012 | ||
| si:ch211-93f2.1 | si:ch211-93f2.1 | 0.011 | ||
| im:7138629 | im:7138629 | 0.011 | ||
| gcshb | glycine cleavage system protein H (aminomethyl carrier), b | 0.011 | ||
| uox | urate oxidase | 0.011 | ||
| irf9 | interferon regulatory factor 9 | 0.011 | ||
| LOC559127 | similar to AWKS9372 | 0.011 | ||
| LOC100005232 | Gig2-like protein DreD | 0.011 | ||
| serpinb1l3 | serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 | 0.011 | ||
| acox3 | acyl-Coenzyme A oxidase 3, pristanoyl | 0.011 | ||
| grk5 | G protein-coupled receptor kinase 5 | 0.011 | ||
| ela2 | elastase 2 | 0.011 | ||
| cpa1 | carboxypeptidase A1 (pancreatic) | 0.011 | ||
| lonp2 | lon peptidase 2, peroxisomal | 0.010 | ||
| sult3st1 | sulfotransferase family 3, cytosolic sulfotransferase 1 | 0.010 | ||
| bbs7 | Bardet-Biedl syndrome 7 | 0.010 | ||
| slc25a27 | solute carrier family 25, member 27 | 0.010 | ||
| gstal | glutathione S-transferase, alpha-like | 0.010 | ||
| adh8a | alcohol dehydrogenase 8a | 0.010 | ||
| cldnc | claudin c | 0.010 | ||
| cldn11b | claudin 11b | 0.010 |