Danio rerio

0 known processes

hoxa1a

homeo box A1a

(Aliases: id:ibd3526,Hox-a1,hoxa3a,z-4)

hoxa1a biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
neuron development GO:0048666 262 0.909
Mouse
neuron differentiation GO:0030182 353 0.769
Mouse
generation of neurons GO:0048699 385 0.594
Mouse
immune system process GO:0002376 241 0.556
signal transduction GO:0007165 455 0.536
neuron projection morphogenesis GO:0048812 161 0.535
Mouse
cell projection organization GO:0030030 284 0.525
Mouse
chordate embryonic development GO:0043009 271 0.510
Human Zebrafish
cell surface receptor signaling pathway GO:0007166 325 0.509
embryo development ending in birth or egg hatching GO:0009792 271 0.485
Human Zebrafish
head development GO:0060322 303 0.461
Zebrafish Mouse Fly
axon development GO:0061564 166 0.445
Mouse
immune system development GO:0002520 191 0.419
response to chemical GO:0042221 320 0.418
Mouse
camera type eye development GO:0043010 222 0.416
digestive system development GO:0055123 289 0.410
regulation of response to stimulus GO:0048583 269 0.399
Human
skeletal system development GO:0001501 181 0.395
Human
sensory organ morphogenesis GO:0090596 200 0.372
Human Mouse
aromatic compound biosynthetic process GO:0019438 217 0.356
Zebrafish Mouse
regulation of macromolecule metabolic process GO:0060255 317 0.348
Zebrafish Mouse
digestive tract development GO:0048565 265 0.343
regeneration GO:0031099 91 0.303
retinal ganglion cell axon guidance GO:0031290 35 0.284
cellular biosynthetic process GO:0044249 286 0.281
Zebrafish Mouse
regulation of gene expression GO:0010468 265 0.263
Zebrafish Mouse
neuron projection development GO:0031175 180 0.263
Mouse
muscle structure development GO:0061061 196 0.261
cell morphogenesis GO:0000902 289 0.255
Mouse
cell part morphogenesis GO:0032990 246 0.252
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.247
Zebrafish Mouse
regulation of metabolic process GO:0019222 359 0.246
Zebrafish Mouse
rna biosynthetic process GO:0032774 181 0.245
Zebrafish Mouse
embryonic skeletal system development GO:0048706 97 0.243
Human
organic substance biosynthetic process GO:1901576 289 0.241
Zebrafish Mouse
macromolecule biosynthetic process GO:0009059 227 0.237
Zebrafish Mouse
muscle cell differentiation GO:0042692 139 0.231
cellular component morphogenesis GO:0032989 336 0.227
Mouse
regulation of multicellular organismal process GO:0051239 277 0.225
digestive tract morphogenesis GO:0048546 231 0.218
response to stress GO:0006950 263 0.213
embryonic cranial skeleton morphogenesis GO:0048701 90 0.213
Human
central nervous system neuron differentiation GO:0021953 74 0.212
Mouse
cellular aromatic compound metabolic process GO:0006725 295 0.204
Zebrafish Mouse
cell fate specification GO:0001708 68 0.198
blood vessel morphogenesis GO:0048514 216 0.198
Human
heart development GO:0007507 313 0.193
gastrulation GO:0007369 208 0.187
stem cell proliferation GO:0072089 4 0.181
heart morphogenesis GO:0003007 156 0.180
gene expression GO:0010467 252 0.178
Zebrafish Mouse
tube morphogenesis GO:0035239 349 0.176
Human Zebrafish
axonogenesis GO:0007409 152 0.174
Mouse
retina development in camera type eye GO:0060041 146 0.172
regulation of primary metabolic process GO:0080090 311 0.172
Zebrafish Mouse
embryonic organ morphogenesis GO:0048562 274 0.166
Human Mouse
determination of bilateral symmetry GO:0009855 204 0.161
cell projection morphogenesis GO:0048858 244 0.160
Mouse
neuron projection guidance GO:0097485 86 0.159
Mouse
organic cyclic compound biosynthetic process GO:1901362 223 0.159
Zebrafish Mouse
nucleic acid metabolic process GO:0090304 244 0.159
Zebrafish Mouse
nitrogen compound metabolic process GO:0006807 319 0.157
Zebrafish Mouse
axon guidance GO:0007411 86 0.156
Mouse
cell morphogenesis involved in differentiation GO:0000904 195 0.150
Mouse
single organism organelle organization GO:1902589 199 0.149
Zebrafish
organic cyclic compound metabolic process GO:1901360 301 0.148
Zebrafish Mouse
embryonic skeletal system morphogenesis GO:0048704 93 0.147
Human
embryonic heart tube development GO:0035050 133 0.145
muscle tissue development GO:0060537 110 0.144
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.143
Mouse
determination of heart left right asymmetry GO:0061371 117 0.142
cellular macromolecule metabolic process GO:0044260 391 0.140
Zebrafish Mouse
regulation of signal transduction GO:0009966 225 0.139
regulation of axonogenesis GO:0050770 32 0.134
blood vessel development GO:0001568 246 0.132
Human
central nervous system development GO:0007417 387 0.132
Zebrafish Mouse
wound healing GO:0042060 90 0.132
cranial nerve development GO:0021545 42 0.130
Human Zebrafish Mouse
regulation of biological quality GO:0065008 263 0.128
chemotaxis GO:0006935 104 0.124
Mouse
regulation of multicellular organismal development GO:2000026 223 0.121
establishment of localization GO:0051234 244 0.121
Zebrafish
positive regulation of epithelial cell differentiation GO:0030858 2 0.119
cell migration GO:0016477 237 0.119
Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.117
ear development GO:0043583 127 0.117
Human Zebrafish Mouse
striated muscle cell differentiation GO:0051146 129 0.114
response to wounding GO:0009611 116 0.110
regulation of cell differentiation GO:0045595 142 0.109
regulation of axon extension GO:0030516 24 0.108
determination of left right symmetry GO:0007368 179 0.105
nucleobase containing compound metabolic process GO:0006139 274 0.101
Zebrafish Mouse
camera type eye morphogenesis GO:0048593 108 0.099
mesoderm development GO:0007498 88 0.099
regulation of cell communication GO:0010646 232 0.099
response to organic substance GO:0010033 153 0.098
Mouse
appendage development GO:0048736 80 0.097
enzyme linked receptor protein signaling pathway GO:0007167 106 0.096
intracellular receptor signaling pathway GO:0030522 30 0.095
developmental cell growth GO:0048588 52 0.094
muscle cell development GO:0055001 115 0.093
aging GO:0007568 2 0.093
locomotion GO:0040011 313 0.092
Zebrafish Mouse
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.090
convergent extension GO:0060026 118 0.089
nucleobase containing compound biosynthetic process GO:0034654 205 0.089
Zebrafish Mouse
regulation of rna biosynthetic process GO:2001141 213 0.089
Zebrafish Mouse
tissue regeneration GO:0042246 74 0.086
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.086
Zebrafish Mouse
developmental growth GO:0048589 166 0.086
growth GO:0040007 174 0.085
inner ear morphogenesis GO:0042472 63 0.082
Human Mouse
regulation of stem cell proliferation GO:0072091 2 0.082
brain development GO:0007420 293 0.081
Zebrafish Mouse
angiogenesis GO:0001525 158 0.081
dorsal ventral pattern formation GO:0009953 125 0.080
epithelial tube morphogenesis GO:0060562 148 0.080
Zebrafish
protein import GO:0017038 3 0.079
vasculature development GO:0001944 278 0.079
Human
protein targeting to nucleus GO:0044744 3 0.079
regulation of transcription dna templated GO:0006355 213 0.078
Zebrafish Mouse
regulation of macromolecule biosynthetic process GO:0010556 225 0.078
Zebrafish Mouse
biosynthetic process GO:0009058 294 0.078
Zebrafish Mouse
cellular nitrogen compound biosynthetic process GO:0044271 218 0.077
Zebrafish Mouse
neuron projection extension GO:1990138 45 0.076
gland development GO:0048732 143 0.076
inner ear development GO:0048839 126 0.076
Human Zebrafish Mouse
sensory organ development GO:0007423 393 0.075
Human Zebrafish Mouse
actin cytoskeleton organization GO:0030036 63 0.074
morphogenesis of an epithelium GO:0002009 333 0.073
Zebrafish
striated muscle tissue development GO:0014706 110 0.072
photoreceptor cell differentiation GO:0046530 55 0.072
single organism metabolic process GO:0044710 217 0.072
cellular macromolecule biosynthetic process GO:0034645 224 0.070
Zebrafish Mouse
rhombomere formation GO:0021594 12 0.070
Zebrafish
regulation of cytokine production GO:0001817 3 0.070
cell fate commitment GO:0045165 99 0.069
positive regulation of cellular biosynthetic process GO:0031328 68 0.069
Zebrafish Mouse
regulation of signaling GO:0023051 235 0.069
cation homeostasis GO:0055080 33 0.068
transcription dna templated GO:0006351 181 0.067
Zebrafish Mouse
homeostatic process GO:0042592 142 0.067
transcription from rna polymerase ii promoter GO:0006366 80 0.067
Zebrafish Mouse
positive regulation of signal transduction GO:0009967 56 0.065
apoptotic process GO:0006915 116 0.065
negative regulation of cell communication GO:0010648 96 0.064
regionalization GO:0003002 274 0.064
Mouse Fly
regulation of cellular component organization GO:0051128 86 0.064
programmed cell death GO:0012501 119 0.064
developmental growth involved in morphogenesis GO:0060560 86 0.063
taxis GO:0042330 109 0.063
Mouse
ventral spinal cord development GO:0021517 35 0.061
pharyngeal muscle development GO:0043282 4 0.060
regulation of developmental process GO:0050793 247 0.060
heterocycle biosynthetic process GO:0018130 215 0.059
Zebrafish Mouse
larval development GO:0002164 2 0.059
behavior GO:0007610 74 0.058
Human
melanin metabolic process GO:0006582 2 0.058
eye morphogenesis GO:0048592 144 0.057
muscle organ development GO:0007517 101 0.056
nuclear transport GO:0051169 4 0.056
regulation of cellular biosynthetic process GO:0031326 245 0.056
Zebrafish Mouse
hindbrain development GO:0030902 91 0.055
Zebrafish Mouse
regulation of mesenchymal cell proliferation GO:0010464 1 0.055
skeletal muscle tissue development GO:0007519 67 0.054
protein import into nucleus GO:0006606 3 0.053
spindle localization GO:0051653 12 0.053
Zebrafish
positive regulation of biological process GO:0048518 253 0.053
Zebrafish Mouse
system process GO:0003008 185 0.052
Human
macromolecular complex subunit organization GO:0043933 74 0.052
Zebrafish
cell substrate adhesion GO:0031589 4 0.052
establishment of mitotic spindle localization GO:0040001 12 0.051
Zebrafish
regulation of protein complex assembly GO:0043254 3 0.050
connective tissue development GO:0061448 99 0.050
oocyte maturation GO:0001556 4 0.049
striated muscle cell development GO:0055002 108 0.049
erythrocyte homeostasis GO:0034101 55 0.049
neuron projection regeneration GO:0031102 16 0.048
regulation of anatomical structure morphogenesis GO:0022603 130 0.048
transport GO:0006810 220 0.048
regulation of cellular ketone metabolic process GO:0010565 7 0.047
positive regulation of macromolecule metabolic process GO:0010604 93 0.047
Zebrafish Mouse
regulation of transcription from rna polymerase ii promoter involved in heart development GO:1901213 15 0.047
regulation of neuron differentiation GO:0045664 56 0.047
regulation of cellular metabolic process GO:0031323 320 0.046
Zebrafish Mouse
fin development GO:0033333 77 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.046
rhombomere development GO:0021546 19 0.046
Zebrafish Mouse
regulation of molecular function GO:0065009 70 0.045
eye development GO:0001654 277 0.045
multicellular organismal reproductive process GO:0048609 35 0.045
establishment of mitotic spindle orientation GO:0000132 10 0.044
Zebrafish
retina morphogenesis in camera type eye GO:0060042 79 0.044
positive regulation of cell communication GO:0010647 56 0.044
heart looping GO:0001947 94 0.043
regulation of nervous system development GO:0051960 90 0.043
regulation of reproductive process GO:2000241 4 0.043
positive regulation of cytokine production GO:0001819 2 0.042
positive regulation of mesenchymal cell proliferation GO:0002053 1 0.042
negative regulation of signaling GO:0023057 96 0.042
cellular protein catabolic process GO:0044257 4 0.042
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.042
Zebrafish Mouse
cellular nitrogen compound metabolic process GO:0034641 290 0.041
Zebrafish Mouse
ion transport GO:0006811 114 0.041
secondary metabolic process GO:0019748 3 0.041
regulation of establishment of protein localization GO:0070201 4 0.041
negative regulation of signal transduction GO:0009968 94 0.041
regulation of rna metabolic process GO:0051252 224 0.041
Zebrafish Mouse
negative regulation of biological process GO:0048519 304 0.040
appendage morphogenesis GO:0035107 56 0.040
regulation of cell projection organization GO:0031344 44 0.040
positive regulation of stem cell proliferation GO:2000648 1 0.039
multicellular organism growth GO:0035264 4 0.039
regulation of neuron projection development GO:0010975 40 0.039
regulation of anatomical structure size GO:0090066 33 0.039
positive regulation of response to stimulus GO:0048584 80 0.039
formation of primary germ layer GO:0001704 62 0.039
myeloid cell differentiation GO:0030099 86 0.038
positive regulation of catabolic process GO:0009896 4 0.038
blood circulation GO:0008015 87 0.038
nucleic acid templated transcription GO:0097659 181 0.038
Zebrafish Mouse
nuclear import GO:0051170 3 0.038
cell fate commitment involved in formation of primary germ layer GO:0060795 26 0.037
rna metabolic process GO:0016070 219 0.036
Zebrafish Mouse
specification of symmetry GO:0009799 204 0.036
regulation of intracellular signal transduction GO:1902531 57 0.035
regulation of biosynthetic process GO:0009889 250 0.035
Zebrafish Mouse
establishment of protein localization to organelle GO:0072594 4 0.035
embryonic heart tube morphogenesis GO:0003143 108 0.035
gastrulation with mouth forming second GO:0001702 44 0.035
stem cell fate commitment GO:0048865 1 0.035
glial cell migration GO:0008347 3 0.035
regulation of neurogenesis GO:0050767 87 0.034
regulation of cell development GO:0060284 100 0.034
cell death GO:0008219 121 0.034
hindbrain morphogenesis GO:0021575 22 0.034
Zebrafish
amine metabolic process GO:0009308 2 0.033
myeloid cell homeostasis GO:0002262 56 0.033
cardiocyte differentiation GO:0035051 44 0.033
single organism cellular localization GO:1902580 46 0.033
Zebrafish
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.033
multicellular organismal signaling GO:0035637 22 0.033
regulation of multicellular organism growth GO:0040014 4 0.033
regulation of inner ear receptor cell differentiation GO:2000980 1 0.033
nucleocytoplasmic transport GO:0006913 4 0.032
aorta development GO:0035904 4 0.032
regulation of epithelial cell proliferation GO:0050678 3 0.032
proteasomal protein catabolic process GO:0010498 2 0.032
regulation of behavior GO:0050795 24 0.031
Human
microtubule based process GO:0007017 60 0.031
Zebrafish
single organism behavior GO:0044708 24 0.031
Human
response to oxygen containing compound GO:1901700 55 0.031
Mouse
hemopoiesis GO:0030097 183 0.031
bmp signaling pathway involved in heart development GO:0061312 15 0.031
circadian rhythm GO:0007623 19 0.030
cell adhesion mediated by integrin GO:0033627 1 0.030
sensory epithelium regeneration GO:0070654 14 0.030
positive regulation of metabolic process GO:0009893 108 0.030
Zebrafish Mouse
cell differentiation in spinal cord GO:0021515 40 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
negative regulation of secretion GO:0051048 2 0.029
regulation of protein catabolic process GO:0042176 1 0.029
renal system development GO:0072001 94 0.029
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
Zebrafish Mouse
mitotic cell cycle process GO:1903047 48 0.029
Zebrafish
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.029
cell motility GO:0048870 244 0.029
Zebrafish
negative regulation of cellular process GO:0048523 283 0.028
response to external stimulus GO:0009605 264 0.028
Mouse
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 2 0.028
meiotic nuclear division GO:0007126 4 0.028
facial nerve development GO:0021561 3 0.028
Zebrafish Mouse
hematopoietic or lymphoid organ development GO:0048534 191 0.028
cartilage development GO:0051216 96 0.028
protein activation cascade GO:0072376 6 0.027
regulation of apoptotic process GO:0042981 98 0.027
mesodermal cell fate commitment GO:0001710 14 0.027
negative regulation of protein transport GO:0051224 3 0.027
response to growth factor GO:0070848 39 0.027
compound eye development GO:0048749 2 0.027
modification dependent protein catabolic process GO:0019941 3 0.027
heart contraction GO:0060047 71 0.027
regulation of transmembrane transporter activity GO:0022898 2 0.026
epithelium regeneration GO:1990399 14 0.026
erythrocyte differentiation GO:0030218 54 0.026
carboxylic acid metabolic process GO:0019752 22 0.026
positive regulation of cellular process GO:0048522 201 0.026
Zebrafish Mouse
immune response GO:0006955 28 0.026
olfactory lobe development GO:0021988 4 0.026
response to external biotic stimulus GO:0043207 97 0.025
protein secretion GO:0009306 1 0.025
neural nucleus development GO:0048857 15 0.025
Zebrafish Mouse
embryonic camera type eye morphogenesis GO:0048596 19 0.025
cellular component assembly GO:0022607 170 0.025
skeletal system morphogenesis GO:0048705 102 0.025
Human
cellular ketone metabolic process GO:0042180 11 0.024
heart process GO:0003015 71 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
cellular response to chemical stimulus GO:0070887 157 0.024
Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.024
pharyngeal system development GO:0060037 18 0.024
post anal tail morphogenesis GO:0036342 19 0.024
axon extension GO:0048675 45 0.024
single organism transport GO:0044765 206 0.024
circulatory system process GO:0003013 87 0.024
regulation of circadian rhythm GO:0042752 4 0.024
peptidyl serine modification GO:0018209 2 0.024
positive regulation of cellular component biogenesis GO:0044089 3 0.024
negative regulation of cytokine production GO:0001818 1 0.024
bmp signaling pathway GO:0030509 52 0.023
negative regulation of catalytic activity GO:0043086 21 0.023
extrinsic apoptotic signaling pathway GO:0097191 3 0.023
cellular amine metabolic process GO:0044106 2 0.023
modification dependent macromolecule catabolic process GO:0043632 3 0.023
single organism nuclear import GO:1902593 3 0.023
cellular component biogenesis GO:0044085 178 0.023
regulation of transporter activity GO:0032409 2 0.022
nerve development GO:0021675 45 0.022
Human Zebrafish Mouse
anterior posterior pattern specification GO:0009952 152 0.022
Mouse
fin morphogenesis GO:0033334 53 0.022
regulation of extent of cell growth GO:0061387 29 0.022
ear morphogenesis GO:0042471 64 0.022
Human Mouse
skeletal muscle organ development GO:0060538 78 0.022
forebrain development GO:0030900 96 0.022
macromolecule modification GO:0043412 111 0.022
morphogenesis of embryonic epithelium GO:0016331 30 0.022
Zebrafish
positive regulation of rna biosynthetic process GO:1902680 57 0.022
Zebrafish Mouse
regulation of cell death GO:0010941 103 0.022
regulation of protein transport GO:0051223 3 0.022
cytoskeleton organization GO:0007010 96 0.022
Zebrafish
axon regeneration GO:0031103 14 0.021
segmentation GO:0035282 97 0.021
Fly
organelle organization GO:0006996 227 0.021
Zebrafish
positive regulation of rna metabolic process GO:0051254 59 0.021
Zebrafish Mouse
transmembrane transport GO:0055085 120 0.021
eye field cell fate commitment involved in camera type eye formation GO:0060898 3 0.021
exocrine system development GO:0035272 28 0.021
regulation of transcription from rna polymerase ii promoter involved in determination of left right symmetry GO:1900094 17 0.021
regulation of protein metabolic process GO:0051246 56 0.021
regulation of cell proliferation GO:0042127 37 0.021
cell proliferation GO:0008283 80 0.021
regulation of erk1 and erk2 cascade GO:0070372 4 0.021
ion transmembrane transport GO:0034220 91 0.021
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 4 0.021
positive regulation of biosynthetic process GO:0009891 68 0.021
Zebrafish Mouse
regulation of angiogenesis GO:0045765 26 0.020
regulation of vasculature development GO:1901342 33 0.020
heterocycle metabolic process GO:0046483 290 0.020
Zebrafish Mouse
muscle fiber development GO:0048747 52 0.020
fin regeneration GO:0031101 51 0.020
cellular component movement GO:0006928 335 0.020
Zebrafish Mouse
regulation of organ morphogenesis GO:2000027 35 0.020
positive regulation of nucleic acid templated transcription GO:1903508 57 0.020
Zebrafish Mouse
protein localization to nucleus GO:0034504 3 0.020
keratinocyte differentiation GO:0030216 0 0.020
gabaergic neuron differentiation GO:0097154 2 0.020
cell cycle process GO:0022402 53 0.020
Zebrafish
organic acid metabolic process GO:0006082 31 0.019
regulation of cellular amine metabolic process GO:0033238 0 0.019
embryonic organ development GO:0048568 381 0.019
Human Mouse
axis specification GO:0009798 43 0.019
cell differentiation involved in kidney development GO:0061005 13 0.019
negative regulation of cellular biosynthetic process GO:0031327 55 0.019
negative regulation of macromolecule metabolic process GO:0010605 76 0.019
regulation of ion transmembrane transporter activity GO:0032412 2 0.019
intracellular signal transduction GO:0035556 85 0.019
cellular response to organic substance GO:0071310 105 0.019
Mouse
oxoacid metabolic process GO:0043436 31 0.018
regulation of protein import into nucleus GO:0042306 2 0.018
peripheral nervous system neuron development GO:0048935 22 0.018
erk1 and erk2 cascade GO:0070371 4 0.018
peptidyl serine phosphorylation GO:0018105 1 0.018
protein metabolic process GO:0019538 183 0.018
negative regulation of intracellular protein transport GO:0090317 3 0.018
cell growth GO:0016049 57 0.018
eye photoreceptor cell differentiation GO:0001754 45 0.018
metal ion homeostasis GO:0055065 26 0.018
sensory perception of pain GO:0019233 1 0.018
cell surface receptor signaling pathway involved in heart development GO:0061311 20 0.018
response to topologically incorrect protein GO:0035966 2 0.018
regulation of catalytic activity GO:0050790 55 0.018
regulation of growth GO:0040008 42 0.017
liver development GO:0001889 96 0.017
cellular protein modification process GO:0006464 100 0.017
pectoral fin development GO:0033339 50 0.017
innate immune response GO:0045087 13 0.017
i kappab kinase nf kappab signaling GO:0007249 4 0.017
positive regulation of cell cycle GO:0045787 3 0.017
response to alkaloid GO:0043279 2 0.017
protein complex assembly GO:0006461 30 0.017
cellular response to external stimulus GO:0071496 2 0.017
regulation of receptor activity GO:0010469 2 0.017
endoderm development GO:0007492 49 0.017
neural retina development GO:0003407 49 0.017
regulation of protein kinase b signaling GO:0051896 8 0.017
negative regulation of anterior neural cell fate commitment of the neural plate by wnt signaling pathway GO:0022002 1 0.017
cellular response to endogenous stimulus GO:0071495 68 0.017
positive regulation of immune effector process GO:0002699 3 0.017
peripheral nervous system neuron differentiation GO:0048934 28 0.017
cardiogenic plate morphogenesis GO:0003142 1 0.017
odontogenesis of dentin containing tooth GO:0042475 1 0.017
determination of ventral identity GO:0048264 21 0.016
cation transport GO:0006812 81 0.016
cell migration involved in gastrulation GO:0042074 79 0.016
defense response GO:0006952 47 0.016
localization of cell GO:0051674 244 0.016
Zebrafish
post embryonic organ development GO:0048569 4 0.016
regulation of bmp signaling pathway GO:0030510 39 0.016
trabecula morphogenesis GO:0061383 2 0.016
regulation of programmed cell death GO:0043067 101 0.016
response to lipid GO:0033993 60 0.016
Mouse
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
neuron fate specification GO:0048665 20 0.016
negative regulation of cellular metabolic process GO:0031324 77 0.016
negative regulation of defense response GO:0031348 2 0.016
anterior head development GO:0097065 2 0.016
mesenchyme development GO:0060485 127 0.016
regulation of binding GO:0051098 3 0.016
phosphorus metabolic process GO:0006793 109 0.016
regulation of fatty acid metabolic process GO:0019217 1 0.016
actomyosin structure organization GO:0031032 53 0.015
positive regulation of cellular catabolic process GO:0031331 3 0.015
positive regulation of gtp catabolic process GO:0033126 1 0.015
guanosine containing compound catabolic process GO:1901069 2 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
neuroblast proliferation GO:0007405 2 0.015
negative regulation of metabolic process GO:0009892 86 0.015
pancreas development GO:0031016 84 0.015
skeletal muscle fiber development GO:0048741 35 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.015
tissue remodeling GO:0048771 4 0.015
spinal cord development GO:0021510 46 0.015
chemical homeostasis GO:0048878 49 0.015
embryonic skeletal joint development GO:0072498 3 0.015
protein complex subunit organization GO:0071822 46 0.015
Zebrafish
cellular response to growth factor stimulus GO:0071363 39 0.015
nephron development GO:0072006 31 0.015
regulation of neural precursor cell proliferation GO:2000177 3 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.015
regulation of phosphorus metabolic process GO:0051174 43 0.015
bmp signaling pathway involved in determination of left right symmetry GO:0003154 14 0.014
pharynx development GO:0060465 5 0.014
neuron fate commitment GO:0048663 26 0.014
single organismal cell cell adhesion GO:0016337 29 0.014
developmental programmed cell death GO:0010623 4 0.014
otic vesicle development GO:0071599 42 0.014
Zebrafish
mesoderm formation GO:0001707 43 0.014
positive regulation of nucleotide catabolic process GO:0030813 1 0.014
exocrine pancreas development GO:0031017 28 0.014
regulation of mechanoreceptor differentiation GO:0045631 1 0.014
endocardial cushion formation GO:0003272 2 0.014
establishment of spindle localization GO:0051293 12 0.014
Zebrafish
homeostasis of number of cells GO:0048872 62 0.014
regulation of neurological system process GO:0031644 2 0.014
small molecule metabolic process GO:0044281 77 0.014
regulation of purine nucleotide metabolic process GO:1900542 17 0.014
skin development GO:0043588 54 0.014
determination of dorsal ventral asymmetry GO:0048262 34 0.014
phosphate containing compound metabolic process GO:0006796 108 0.014
positive regulation of cell differentiation GO:0045597 30 0.014
opioid receptor signaling pathway GO:0038003 3 0.014
maintenance of location GO:0051235 4 0.014
ubiquitin dependent protein catabolic process GO:0006511 3 0.014
urogenital system development GO:0001655 97 0.013
cellular amino acid metabolic process GO:0006520 7 0.013
endocrine system development GO:0035270 65 0.013
mesodermal cell migration GO:0008078 12 0.013
myotube differentiation GO:0014902 45 0.013
immune effector process GO:0002252 23 0.013
mitotic cell cycle GO:0000278 64 0.013
Zebrafish
macromolecule localization GO:0033036 54 0.013
regulation of cell activation GO:0050865 1 0.013
lipid storage GO:0019915 1 0.013
stem cell maintenance GO:0019827 4 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
negative regulation of cell death GO:0060548 60 0.013
negative regulation of apoptotic process GO:0043066 55 0.013
lateral mesoderm development GO:0048368 23 0.013
positive regulation of multicellular organismal process GO:0051240 52 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
regulation of nucleoside metabolic process GO:0009118 2 0.013
regulation of anterior head development GO:2000742 2 0.013
cell cell signaling GO:0007267 52 0.013
olfactory bulb development GO:0021772 4 0.013
neurological system process GO:0050877 62 0.013
Human
carbohydrate homeostasis GO:0033500 1 0.013
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.012
protein complex biogenesis GO:0070271 30 0.012
primary neural tube formation GO:0014020 1 0.012
Zebrafish
regulation of wnt signaling pathway GO:0030111 53 0.012

hoxa1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.063
bone development disease DOID:0080006 0 0.051
bone disease DOID:0080001 0 0.051
musculoskeletal system disease DOID:17 0 0.051
connective tissue disease DOID:65 0 0.051
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019
nervous system disease DOID:863 0 0.015