Danio rerio

59 known processes

id2a

inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a

(Aliases: cb321,wu:fa04e03,id2)

id2a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neural tube development GO:0021915 62 0.912
immune system development GO:0002520 191 0.500
Mouse
regulation of nucleic acid templated transcription GO:1903506 213 0.484
Human Mouse Fly
chordate embryonic development GO:0043009 271 0.450
response to abiotic stimulus GO:0009628 122 0.422
Mouse
leukocyte differentiation GO:0002521 25 0.410
Mouse
cell cycle GO:0007049 93 0.404
mitotic dna damage checkpoint GO:0044773 4 0.402
neural tube formation GO:0001841 16 0.383
cellular aromatic compound metabolic process GO:0006725 295 0.382
Human Mouse Fly
lipid storage GO:0019915 1 0.348
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.323
Human Mouse Fly
hemopoiesis GO:0030097 183 0.323
Mouse
regulation of transcription dna templated GO:0006355 213 0.316
Human Mouse Fly
epithelial tube morphogenesis GO:0060562 148 0.313
head development GO:0060322 303 0.299
Mouse Fly
nucleobase containing compound metabolic process GO:0006139 274 0.292
Human Mouse Fly
maintenance of location GO:0051235 4 0.286
hematopoietic or lymphoid organ development GO:0048534 191 0.274
Mouse
rna biosynthetic process GO:0032774 181 0.271
Human Mouse Fly
embryonic organ morphogenesis GO:0048562 274 0.263
Mouse
heart looping GO:0001947 94 0.256
regulation of rna biosynthetic process GO:2001141 213 0.256
Human Mouse Fly
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.243
negative regulation of cell cycle GO:0045786 14 0.239
tube morphogenesis GO:0035239 349 0.232
Mouse
transcription dna templated GO:0006351 181 0.215
Human Mouse Fly
photoreceptor cell fate commitment GO:0046552 1 0.208
Fly
heart development GO:0007507 313 0.200
Mouse
digestive system development GO:0055123 289 0.195
Mouse Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.193
Human Mouse Fly
aorta morphogenesis GO:0035909 3 0.176
lymphatic endothelial cell differentiation GO:0060836 1 0.175
negative regulation of biological process GO:0048519 304 0.174
regulation of biological quality GO:0065008 263 0.171
Mouse
cell fate specification GO:0001708 68 0.170
nuclear transport GO:0051169 4 0.166
negative regulation of cell cycle process GO:0010948 9 0.163
cellular macromolecule biosynthetic process GO:0034645 224 0.151
Human Mouse Fly
neural precursor cell proliferation GO:0061351 20 0.149
Mouse
cellular biosynthetic process GO:0044249 286 0.147
Human Mouse Fly
ameboidal type cell migration GO:0001667 143 0.146
locomotion GO:0040011 313 0.141
Fly
regulation of primary metabolic process GO:0080090 311 0.135
Human Mouse Fly
positive regulation of biological process GO:0048518 253 0.134
Mouse
negative regulation of cellular process GO:0048523 283 0.132
intra s dna damage checkpoint GO:0031573 1 0.131
rna metabolic process GO:0016070 219 0.129
Human Mouse Fly
cellular macromolecule metabolic process GO:0044260 391 0.125
Human Mouse Fly
embryonic organ development GO:0048568 381 0.124
Mouse
regulation of biosynthetic process GO:0009889 250 0.121
Human Mouse Fly
positive regulation of secretion by cell GO:1903532 1 0.121
organic cyclic compound metabolic process GO:1901360 301 0.114
Human Mouse Fly
regulation of metal ion transport GO:0010959 4 0.112
apoptotic process GO:0006915 116 0.111
nucleocytoplasmic transport GO:0006913 4 0.111
lateral inhibition GO:0046331 1 0.109
Fly
brain development GO:0007420 293 0.108
Mouse Fly
brain morphogenesis GO:0048854 18 0.105
Fly
positive regulation of transport GO:0051050 2 0.105
organelle organization GO:0006996 227 0.104
mitotic cell cycle GO:0000278 64 0.104
nucleic acid metabolic process GO:0090304 244 0.104
Human Mouse Fly
regulation of leukocyte differentiation GO:1902105 5 0.103
Mouse
immune system process GO:0002376 241 0.101
Mouse
cell type specific apoptotic process GO:0097285 22 0.099
response to corticosteroid GO:0031960 1 0.098
mitotic cell cycle process GO:1903047 48 0.096
generation of neurons GO:0048699 385 0.095
determination of heart left right asymmetry GO:0061371 117 0.092
regulation of metabolic process GO:0019222 359 0.091
Human Mouse Fly
regulation of gene expression GO:0010468 265 0.089
Human Mouse Fly
regulation of macromolecule metabolic process GO:0060255 317 0.088
Human Mouse Fly
regulation of wnt signaling pathway GO:0030111 53 0.088
canonical wnt signaling pathway GO:0060070 48 0.085
embryonic heart tube development GO:0035050 133 0.085
negative regulation of programmed cell death GO:0043069 58 0.083
biosynthetic process GO:0009058 294 0.083
Human Mouse Fly
cellular response to dna damage stimulus GO:0006974 24 0.083
myeloid leukocyte differentiation GO:0002573 15 0.082
Mouse
regulation of binding GO:0051098 3 0.082
Mouse Fly
cation transport GO:0006812 81 0.081
positive regulation of muscle tissue development GO:1901863 1 0.080
negative regulation of biosynthetic process GO:0009890 55 0.079
Human Mouse Fly
olfactory bulb development GO:0021772 4 0.078
Mouse
erythrocyte differentiation GO:0030218 54 0.078
Mouse
regulation of multicellular organismal process GO:0051239 277 0.078
regulation of skeletal muscle tissue development GO:0048641 4 0.075
positive regulation of secretion GO:0051047 1 0.075
embryonic skeletal system development GO:0048706 97 0.072
regulation of rna metabolic process GO:0051252 224 0.072
Human Mouse Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.071
Human Mouse Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.071
Human Mouse Fly
response to hormone GO:0009725 48 0.070
regulation of nitrogen compound metabolic process GO:0051171 251 0.069
Human Mouse Fly
phagocytosis GO:0006909 3 0.068
cell activation GO:0001775 16 0.067
Mouse
negative regulation of protein transport GO:0051224 3 0.066
cellular component movement GO:0006928 335 0.066
aorta development GO:0035904 4 0.066
positive regulation of cell cycle GO:0045787 3 0.066
Mouse
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 8 0.065
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.065
Human
regulation of cellular metabolic process GO:0031323 320 0.065
Human Mouse Fly
regulation of protein ubiquitination GO:0031396 3 0.063
intracellular transport GO:0046907 32 0.063
negative regulation of transcription dna templated GO:0045892 45 0.061
Human Mouse Fly
gliogenesis GO:0042063 45 0.061
Mouse
endocrine system development GO:0035270 65 0.059
specification of symmetry GO:0009799 204 0.059
larval development GO:0002164 2 0.059
regulation of localization GO:0032879 104 0.059
determination of bilateral symmetry GO:0009855 204 0.058
programmed cell death GO:0012501 119 0.058
regulation of cytokine production GO:0001817 3 0.057
cell migration GO:0016477 237 0.056
response to hexose GO:0009746 3 0.056
positive regulation of programmed cell death GO:0043068 29 0.055
establishment of cell polarity GO:0030010 18 0.055
forebrain anterior posterior pattern specification GO:0021797 3 0.054
response to hypoxia GO:0001666 25 0.053
signal transduction GO:0007165 455 0.053
response to ketone GO:1901654 1 0.053
cell fate commitment GO:0045165 99 0.053
Mouse Fly
aging GO:0007568 2 0.052
Mouse
regulation of developmental process GO:0050793 247 0.052
cellular response to external stimulus GO:0071496 2 0.052
aromatic compound biosynthetic process GO:0019438 217 0.052
Human Mouse Fly
convergent extension involved in organogenesis GO:0060029 10 0.052
negative regulation of cellular biosynthetic process GO:0031327 55 0.052
Human Mouse Fly
endothelial cell fate commitment GO:0060839 3 0.052
transport GO:0006810 220 0.050
camera type eye development GO:0043010 222 0.050
cell proliferation GO:0008283 80 0.050
Mouse Fly
negative regulation of cellular metabolic process GO:0031324 77 0.049
Human Mouse Fly
regulation of establishment of cell polarity GO:2000114 1 0.049
regulation of cytoplasmic transport GO:1903649 4 0.047
establishment of localization GO:0051234 244 0.047
positive regulation of cellular process GO:0048522 201 0.046
Mouse
system process GO:0003008 185 0.045
Mouse Fly
macromolecule localization GO:0033036 54 0.045
response to decreased oxygen levels GO:0036293 25 0.045
neural tube patterning GO:0021532 33 0.045
regulation of molecular function GO:0065009 70 0.045
Human Mouse Fly
cell motility GO:0048870 244 0.044
regulation of protein transport GO:0051223 3 0.044
response to light stimulus GO:0009416 46 0.044
Mouse
response to stress GO:0006950 263 0.044
nucleobase containing compound biosynthetic process GO:0034654 205 0.044
Human Mouse Fly
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.043
regulation of oligodendrocyte differentiation GO:0048713 1 0.042
Mouse
protein acylation GO:0043543 3 0.042
cell cycle checkpoint GO:0000075 7 0.042
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.042
spinal cord association neuron differentiation GO:0021527 1 0.041
wound healing GO:0042060 90 0.041
establishment of protein localization to organelle GO:0072594 4 0.040
regulation of transcription from rna polymerase iii promoter GO:0006359 1 0.039
single organism intracellular transport GO:1902582 25 0.039
meiotic nuclear division GO:0007126 4 0.039
neuron fate commitment GO:0048663 26 0.039
Mouse Fly
response to monosaccharide GO:0034284 3 0.039
wnt signaling pathway GO:0016055 80 0.039
epithelial cell differentiation GO:0030855 116 0.038
Mouse Fly
cognition GO:0050890 1 0.038
response to radiation GO:0009314 51 0.038
Mouse
protein metabolic process GO:0019538 183 0.038
cellular response to antibiotic GO:0071236 1 0.038
negative regulation of nucleic acid templated transcription GO:1903507 45 0.037
Human Mouse Fly
cell proliferation in hindbrain GO:0021534 4 0.037
organelle assembly GO:0070925 110 0.037
lymphatic endothelial cell fate commitment GO:0060838 1 0.037
organic substance biosynthetic process GO:1901576 289 0.036
Human Mouse Fly
positive regulation of cellular metabolic process GO:0031325 94 0.036
Mouse
cell death GO:0008219 121 0.036
dna integrity checkpoint GO:0031570 6 0.036
cellular nitrogen compound biosynthetic process GO:0044271 218 0.036
Human Mouse Fly
peptidyl lysine acetylation GO:0018394 2 0.036
endodermal cell differentiation GO:0035987 19 0.035
single organism transport GO:0044765 206 0.035
negative regulation of leukocyte chemotaxis GO:0002689 3 0.035
regulation of programmed cell death GO:0043067 101 0.035
retinoic acid receptor signaling pathway GO:0048384 16 0.035
embryonic epithelial tube formation GO:0001838 17 0.035
cerebellar granular layer development GO:0021681 3 0.035
positive regulation of striated muscle cell differentiation GO:0051155 1 0.035
rostrocaudal neural tube patterning GO:0021903 29 0.034
adult behavior GO:0030534 2 0.034
auditory receptor cell fate commitment GO:0009912 4 0.033
regulation of canonical wnt signaling pathway GO:0060828 34 0.033
regulation of ion transport GO:0043269 22 0.033
positive regulation of metabolic process GO:0009893 108 0.032
Mouse
glial cell differentiation GO:0010001 42 0.032
Mouse
positive regulation of neuron migration GO:2001224 2 0.032
b cell activation GO:0042113 2 0.032
Mouse
morphogenesis of an epithelium GO:0002009 333 0.032
Fly
negative regulation of rna biosynthetic process GO:1902679 45 0.032
Human Mouse Fly
peripheral nervous system development GO:0007422 55 0.032
Fly
regulation of apoptotic process GO:0042981 98 0.031
neuron fate determination GO:0048664 2 0.031
regulation of establishment of protein localization GO:0070201 4 0.031
digestive tract development GO:0048565 265 0.031
Mouse Fly
embryonic skeletal system morphogenesis GO:0048704 93 0.031
nuclear division GO:0000280 23 0.031
cell cycle process GO:0022402 53 0.031
membrane invagination GO:0010324 1 0.031
negative regulation of intracellular signal transduction GO:1902532 22 0.031
response to steroid hormone GO:0048545 35 0.030
sensory organ development GO:0007423 393 0.030
Fly
response to glucose GO:0009749 3 0.030
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.030
cellular response to prostaglandin stimulus GO:0071379 3 0.030
nitrogen compound metabolic process GO:0006807 319 0.030
Human Mouse Fly
mitotic dna integrity checkpoint GO:0044774 4 0.030
stem cell proliferation GO:0072089 4 0.030
cell differentiation in spinal cord GO:0021515 40 0.030
cellular response to lipid GO:0071396 39 0.030
positive regulation of cell death GO:0010942 29 0.029
neurological system process GO:0050877 62 0.029
Fly
g1 s transition of mitotic cell cycle GO:0000082 1 0.029
Human
regulation of cell communication GO:0010646 232 0.029
myeloid cell development GO:0061515 32 0.029
protein stabilization GO:0050821 2 0.029
cellular protein modification process GO:0006464 100 0.029
response to glucocorticoid GO:0051384 1 0.028
regulation of cell development GO:0060284 100 0.028
t cell differentiation GO:0030217 6 0.028
photoreceptor cell differentiation GO:0046530 55 0.028
Fly
macromolecule modification GO:0043412 111 0.028
protein modification process GO:0036211 100 0.028
primary neural tube formation GO:0014020 1 0.027
cell fate determination GO:0001709 7 0.027
determination of left right symmetry GO:0007368 179 0.027
spindle localization GO:0051653 12 0.027
embryo development ending in birth or egg hatching GO:0009792 271 0.027
Fly
response to drug GO:0042493 3 0.027
regulation of cell activation GO:0050865 1 0.027
Mouse
negative regulation of macromolecule metabolic process GO:0010605 76 0.027
Human Mouse Fly
embryonic heart tube morphogenesis GO:0003143 108 0.026
regulation of endodermal cell fate specification GO:0042663 15 0.026
forebrain neuron differentiation GO:0021879 14 0.026
negative regulation of gene expression GO:0010629 65 0.026
Human Mouse Fly
neuroblast proliferation GO:0007405 2 0.026
neuron neuron synaptic transmission GO:0007270 1 0.026
death GO:0016265 121 0.026
glial cell development GO:0021782 20 0.026
Mouse
cellular response to retinoic acid GO:0071300 1 0.026
endocardial cushion formation GO:0003272 2 0.025
response to wounding GO:0009611 116 0.025
protein secretion GO:0009306 1 0.025
cellular response to steroid hormone stimulus GO:0071383 31 0.025
mononuclear cell proliferation GO:0032943 1 0.025
regionalization GO:0003002 274 0.025
Fly
central nervous system development GO:0007417 387 0.024
Mouse Fly
lateral line development GO:0048882 66 0.024
cell cycle g1 s phase transition GO:0044843 1 0.024
Human
heterocycle biosynthetic process GO:0018130 215 0.024
Human Mouse Fly
cellular response to fatty acid GO:0071398 3 0.024
spermatid differentiation GO:0048515 2 0.024
Fly
positive regulation of immune effector process GO:0002699 3 0.023
primitive erythrocyte differentiation GO:0060319 5 0.023
epithelial cell fate commitment GO:0072148 11 0.023
positive regulation of cytokine production GO:0001819 2 0.023
mitotic cell cycle embryonic GO:0045448 2 0.023
protein localization GO:0008104 40 0.023
cellular response to hormone stimulus GO:0032870 39 0.023
epiboly GO:0090504 41 0.022
protein acetylation GO:0006473 2 0.022
negative regulation of cell communication GO:0010648 96 0.022
positive regulation of histone modification GO:0031058 1 0.022
neuromast development GO:0048884 46 0.022
mitochondrion organization GO:0007005 4 0.022
positive regulation of myeloid cell differentiation GO:0045639 2 0.022
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.022
Human Mouse Fly
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.022
Human Mouse Fly
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.022
cellular monovalent inorganic cation homeostasis GO:0030004 2 0.022
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.022
negative regulation of signaling GO:0023057 96 0.021
amine metabolic process GO:0009308 2 0.021
endodermal digestive tract morphogenesis GO:0061031 2 0.021
Mouse
regulation of dendrite development GO:0050773 3 0.021
cellular response to radiation GO:0071478 4 0.021
cellular response to stress GO:0033554 62 0.021
cellular nitrogen compound metabolic process GO:0034641 290 0.021
Human Mouse Fly
regulation of neuron migration GO:2001222 2 0.021
regulation of transport GO:0051049 45 0.021
astrocyte differentiation GO:0048708 1 0.021
Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.021
Mouse
regulation of transmembrane transporter activity GO:0022898 2 0.021
negative regulation of wnt signaling pathway GO:0030178 30 0.021
posterior lateral line system development GO:0048915 46 0.021
peripheral nervous system neuron differentiation GO:0048934 28 0.021
positive regulation of cell division GO:0051781 2 0.020
cell proliferation in forebrain GO:0021846 3 0.020
meiotic cell cycle process GO:1903046 3 0.020
cellular amine metabolic process GO:0044106 2 0.020
cellular protein metabolic process GO:0044267 129 0.020
positive regulation of multicellular organismal process GO:0051240 52 0.020
Mouse
regulation of synaptic plasticity GO:0048167 1 0.019
negative regulation of cell cycle phase transition GO:1901988 5 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
single organism nuclear import GO:1902593 3 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.019
tube closure GO:0060606 1 0.019
epithelial tube formation GO:0072175 19 0.019
nuclear import GO:0051170 3 0.019
mitotic cell cycle checkpoint GO:0007093 5 0.019
regulation of gastrulation GO:0010470 24 0.019
chemosensory behavior GO:0007635 1 0.018
positive regulation of histone deacetylation GO:0031065 1 0.018
positive regulation of neuron apoptotic process GO:0043525 1 0.018
female gonad development GO:0008585 4 0.018
gene expression GO:0010467 252 0.018
Human Mouse Fly
protein import into nucleus GO:0006606 3 0.018
positive regulation of striated muscle tissue development GO:0045844 1 0.018
positive regulation of leukocyte differentiation GO:1902107 1 0.018
Mouse
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.017
digestive tract morphogenesis GO:0048546 231 0.017
Mouse
cell cycle arrest GO:0007050 1 0.017
Mouse
intracellular steroid hormone receptor signaling pathway GO:0030518 5 0.017
negative regulation of myeloid cell differentiation GO:0045638 1 0.017
ion homeostasis GO:0050801 41 0.017
stem cell maintenance GO:0019827 4 0.017
intracellular receptor signaling pathway GO:0030522 30 0.017
single organism localization GO:1902578 225 0.017
cell migration to the midline involved in heart development GO:0003318 12 0.017
negative regulation of apoptotic process GO:0043066 55 0.017
negative regulation of neutrophil chemotaxis GO:0090024 3 0.017
regulation of cardiac muscle tissue development GO:0055024 1 0.017
positive regulation of chromosome organization GO:2001252 1 0.016
negative regulation of protein kinase activity GO:0006469 4 0.016
cellular response to extracellular stimulus GO:0031668 2 0.016
embryonic limb morphogenesis GO:0030326 2 0.016
tube formation GO:0035148 25 0.016
establishment of mitotic spindle localization GO:0040001 12 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.016
Mouse Fly
regulation of multicellular organismal development GO:2000026 223 0.016
gastrulation with mouth forming second GO:0001702 44 0.016
pancreatic a cell development GO:0003322 2 0.016
lymphocyte proliferation GO:0046651 1 0.016
nuclear envelope organization GO:0006998 2 0.016
induction of positive chemotaxis GO:0050930 4 0.016
endodermal cell fate determination GO:0007493 2 0.016
response to nutrient GO:0007584 3 0.016
regulation of immune system process GO:0002682 34 0.016
Mouse
transcription from rna polymerase iii promoter GO:0006383 1 0.016
positive regulation of neuron death GO:1901216 1 0.015
single organism organelle organization GO:1902589 199 0.015
adherens junction organization GO:0034332 4 0.015
cellular process involved in reproduction in multicellular organism GO:0022412 28 0.015
Fly
protein localization to nucleus GO:0034504 3 0.015
regulation of cellular amine metabolic process GO:0033238 0 0.015
organic substance transport GO:0071702 58 0.015
forebrain regionalization GO:0021871 4 0.015
innervation GO:0060384 3 0.015
stem cell fate determination GO:0048867 1 0.015
heterocycle metabolic process GO:0046483 290 0.015
Human Mouse Fly
multicellular organism growth GO:0035264 4 0.015
endocardial cushion morphogenesis GO:0003203 3 0.015
regulation of cell shape GO:0008360 1 0.015
nuclear export GO:0051168 1 0.015
regulation of cellular biosynthetic process GO:0031326 245 0.015
Human Mouse Fly
protein ubiquitination GO:0016567 11 0.015
optic placode formation involved in camera type eye formation GO:0046619 3 0.014
oocyte maturation GO:0001556 4 0.014
regulation of skeletal muscle fiber development GO:0048742 2 0.014
sensory organ morphogenesis GO:0090596 200 0.014
Fly
protein import GO:0017038 3 0.014
intracellular signal transduction GO:0035556 85 0.014
positive regulation of cell differentiation GO:0045597 30 0.014
Mouse
exocrine pancreas development GO:0031017 28 0.014
vasculogenesis GO:0001570 41 0.014
regulation of organ growth GO:0046620 3 0.014
extrinsic apoptotic signaling pathway GO:0097191 3 0.014
positive regulation of exocytosis GO:0045921 1 0.014
regulation of nucleocytoplasmic transport GO:0046822 2 0.014
phagocytosis engulfment GO:0006911 1 0.014
ventral spinal cord development GO:0021517 35 0.014
localization of cell GO:0051674 244 0.013
embryonic viscerocranium morphogenesis GO:0048703 52 0.013
thermosensory behavior GO:0040040 1 0.013
response to oxygen levels GO:0070482 25 0.013
homeostatic process GO:0042592 142 0.013
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.013
Human Mouse Fly
positive regulation of cell proliferation GO:0008284 15 0.013
Mouse
regulation of sequence specific dna binding transcription factor activity GO:0051090 9 0.013
Human
positive regulation of cell activation GO:0050867 1 0.013
auditory receptor cell fate determination GO:0042668 2 0.013
metal ion homeostasis GO:0055065 26 0.013
photoreceptor cell fate specification GO:0043704 1 0.013
hormone transport GO:0009914 2 0.013
positive regulation of cellular component biogenesis GO:0044089 3 0.013
endothelial cell development GO:0001885 12 0.013
pancreas development GO:0031016 84 0.013
cellular component morphogenesis GO:0032989 336 0.013
Fly
regulation of cell death GO:0010941 103 0.013
regulation of cell differentiation GO:0045595 142 0.013
multicellular organismal reproductive process GO:0048609 35 0.013
Fly
fin regeneration GO:0031101 51 0.012
nucleic acid templated transcription GO:0097659 181 0.012
Human Mouse Fly
regulation of cellular protein metabolic process GO:0032268 52 0.012
positive regulation of muscle cell differentiation GO:0051149 1 0.012
hepatocyte proliferation GO:0072574 2 0.012
response to vitamin b3 GO:0033552 2 0.012
negative regulation of rna metabolic process GO:0051253 48 0.012
Human Mouse Fly
neuroblast fate commitment GO:0014017 1 0.012
proteasomal protein catabolic process GO:0010498 2 0.012
response to lipid GO:0033993 60 0.012
embryonic cranial skeleton morphogenesis GO:0048701 90 0.012
positive regulation of oligodendrocyte differentiation GO:0048714 1 0.012
regulation of protein binding GO:0043393 3 0.012
spinal cord development GO:0021510 46 0.012
neural crest cell fate specification GO:0014036 5 0.012
brain segmentation GO:0035284 6 0.012
renal system development GO:0072001 94 0.012
Mouse
transcription from rna polymerase ii promoter GO:0006366 80 0.012
Mouse Fly
muscle structure development GO:0061061 196 0.012
regulation of glial cell differentiation GO:0045685 4 0.012
Mouse
leukocyte activation GO:0045321 12 0.012
Mouse
cellular component maintenance GO:0043954 3 0.012
limb bud formation GO:0060174 2 0.011
ph reduction GO:0045851 1 0.011
negative regulation of metabolic process GO:0009892 86 0.011
Human Mouse Fly
muscle organ development GO:0007517 101 0.011
endothelium development GO:0003158 25 0.011
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.011
germ line stem cell maintenance GO:0030718 2 0.011
behavior GO:0007610 74 0.011
Mouse Fly
cellular response to estradiol stimulus GO:0071392 1 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
cellular response to nutrient levels GO:0031669 2 0.011
regulation of intracellular protein transport GO:0033157 3 0.011
negative regulation of granulocyte chemotaxis GO:0071623 3 0.011
organelle localization GO:0051640 49 0.011
negative regulation of mitotic cell cycle GO:0045930 11 0.011
regulation of translational initiation GO:0006446 1 0.011
convergent extension GO:0060026 118 0.011
hormone secretion GO:0046879 2 0.011
regulation of mrna processing GO:0050684 3 0.011
cellular chemical homeostasis GO:0055082 17 0.011
negative regulation of neutrophil migration GO:1902623 3 0.011
leukocyte proliferation GO:0070661 1 0.011
regulation of protein complex assembly GO:0043254 3 0.011
response to organic cyclic compound GO:0014070 51 0.011
cellular response to starvation GO:0009267 1 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
organonitrogen compound biosynthetic process GO:1901566 47 0.011
central nervous system neuron differentiation GO:0021953 74 0.010
branching morphogenesis of a nerve GO:0048755 4 0.010
multi organism process GO:0051704 134 0.010
Fly
gastrulation GO:0007369 208 0.010
regulation of protein localization to nucleus GO:1900180 2 0.010
regulation of reactive oxygen species metabolic process GO:2000377 2 0.010
negative regulation of intracellular transport GO:0032387 3 0.010
negative regulation of cytoplasmic transport GO:1903650 2 0.010
camera type eye morphogenesis GO:0048593 108 0.010
leukocyte homeostasis GO:0001776 2 0.010
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.010
Human Mouse Fly
response to bacterium GO:0009617 58 0.010
cellular protein catabolic process GO:0044257 4 0.010
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.010
response to uv GO:0009411 3 0.010
chromosome organization GO:0051276 31 0.010
liver morphogenesis GO:0072576 8 0.010
dendrite guidance GO:0070983 0 0.010
cardioblast migration to the midline involved in heart field formation GO:0060975 7 0.010
peptide transport GO:0015833 1 0.010
regulation of endodermal cell differentiation GO:1903224 15 0.010
neuromast deposition GO:0048885 9 0.010
regulation of establishment of planar polarity GO:0090175 4 0.010

id2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.122
cancer DOID:162 0 0.046
disease of cellular proliferation DOID:14566 0 0.046
congenital nervous system abnormality DOID:2490 0 0.025
charcot marie tooth disease DOID:10595 0 0.022
charcot marie tooth disease type 4 DOID:0050541 0 0.022
nervous system disease DOID:863 0 0.022
disease of anatomical entity DOID:7 0 0.022
neuropathy DOID:870 0 0.022
neuromuscular disease DOID:440 0 0.022
organ system cancer DOID:0050686 0 0.015
musculoskeletal system cancer DOID:0060100 0 0.013
intestinal cancer DOID:10155 0 0.012
colon cancer DOID:219 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
large intestine cancer DOID:5672 0 0.012
colon carcinoma DOID:1520 0 0.012
colorectal cancer DOID:9256 0 0.012