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Danio rerio

5 genes annotated in zebrafish

mitotic cell cycle checkpoint

A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mitotic cell cycle checkpoint"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mitotic cell cycle checkpoint" (in gray)

Name	Description	Probability	Func Analog Organism
pcna	proliferating cell nuclear antigen	0.235
ccnd1	cyclin D1	0.214	Human
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.205
ywhae1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1	0.139	Fly
mcm5	MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)	0.136
stil	TAL1 (SCL) interrupting locus	0.130	Mouse
aurkb	aurora kinase B	0.123	Yeast
ccnb1	cyclin B1	0.112	Human
myca	myelocytomatosis oncogene a	0.100
brd2a	bromodomain-containing 2a	0.092
ywhabb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b	0.080
cand1	cullin-associated and neddylation-dissociated 1	0.072
mobkl3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.067
plk1	polo-like kinase 1 (Drosophila)	0.063	Human
tgif1	TGFB-induced factor homeobox 1	0.059
kpna2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.051
ccnb2	cyclin B2	0.047
fen1	flap structure-specific endonuclease 1	0.046
ywhaqa	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a	0.044
pafah1b1b	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b	0.042	Fly
chaf1b	chromatin assembly factor 1, subunit B	0.041
zff9	zinc finger protein 9	0.038
tfam	transcription factor A, mitochondrial	0.038
sumo3a	SMT3 suppressor of mif two 3 homolog 3a	0.037
aurka	aurora kinase A	0.036	Yeast
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.036
cdk8	cyclin-dependent kinase 8	0.036	Fly
rhoab	ras homolog gene family, member Ab	0.035
si:ch211-59d15.5	si:ch211-59d15.5	0.034
rad21	RAD21 homolog (S. pombe)	0.033
ppp2r1a	protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform	0.033	Yeast
ncapg	non-SMC condensin I complex, subunit G	0.029
ywhaba	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a	0.028
ube2g2	ubiquitin-conjugating enzyme E2G 2	0.028
atrx	alpha thalassemia/mental retardation syndrome X-linked homolog (human)	0.028
ccna2	cyclin A2	0.028
g2e3	G2/M-phase specific E3 ubiquitin ligase	0.027
smc3	structural maintenance of chromosomes 3	0.025
chek1	CHK1 checkpoint homolog (S. pombe)	0.024
hug	HuG	0.023
esco2	establishment of cohesion 1 homolog 2	0.023
rrm1	ribonucleotide reductase M1 polypeptide	0.023
ybx1	Y box binding protein 1	0.023
ppp2r5eb	protein phosphatase 2, regulatory subunit B', epsilon isoform b	0.022
tbc1d23	TBC1 domain family, member 23	0.022
pak2b	p21 (CDKN1A)-activated kinase 2b	0.022
pafah1b1a	platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a	0.022	Fly
rpl7a	ribosomal protein L7a	0.022
gnb2l1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.022
fabp7a	fatty acid binding protein 7, brain, a	0.022
naa15b	N(alpha)-acetyltransferase 15, NatA auxiliary subunit b	0.021
snrpd1	small nuclear ribonucleoprotein D1 polypeptide	0.021
sass6	spindle assembly 6 homolog (C. elegans)	0.020
mdm2	transformed 3T3 cell double minute 2 homolog (mouse)	0.020	Human
cstf1	cleavage stimulation factor, 3' pre-RNA, subunit 1	0.020
ing5b	inhibitor of growth family, member 5b	0.020
tia1	cytotoxic granule-associated RNA binding protein 1	0.020
gdf6a	growth differentiation factor 6a	0.019
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.019
kif23	kinesin family member 23	0.018
ck2b	casein kinase 2 beta	0.018
ube2i2	ubiquitin-conjugating enzyme E2I2	0.017	Fly
wu:fq41a10	wu:fq41a10	0.016
rqcd1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.016
orc6	origin recognition complex, subunit 6	0.016
caprin1a	cell cycle associated protein 1a	0.016
srsf1a	serine/arginine-rich splicing factor 1a	0.015	Fly
lsm8	LSM8 homolog, U6 small nuclear RNA associated	0.015
smc1al	structural maintenance of chromosomes 1A, like	0.015	Human
cul3a	cullin 3a	0.015
crip2	cysteine-rich protein 2	0.015
dtl	denticleless homolog (Drosophila)	0.014
rasl11b	RAS-like, family 11, member B	0.014
dnmt5	DNA (cytosine-5-)-methyltransferase 5	0.014
usp4	ubiquitin specific protease 4 (proto-oncogene)	0.014
csnk1g2b	casein kinase 1, gamma 2b	0.014
smc4	structural maintenance of chromosomes 4	0.014
eif2d	eukaryotic translation initiation factor 2D	0.014
nasp	nuclear autoantigenic sperm protein (histone-binding)	0.014
skp2	S-phase kinase-associated protein 2 (p45)	0.013
prkrir	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.013
cdt1	chromatin licensing and DNA replication factor 1	0.013
dct	dopachrome tautomerase	0.013
kif14	kinesin family member 14	0.013
ncapd2	non-SMC condensin I complex, subunit D2	0.013
lrwd1	leucine-rich repeats and WD repeat domain containing 1	0.013
acp5a	acid phosphatase 5a, tartrate resistant	0.012
msh6	mutS homolog 6 (E. coli)	0.012
tmem167a	transmembrane protein 167A	0.012
cdc20	cell division cycle 20 homolog	0.012	Yeast
ccnt2b	cyclin T2b	0.012
zgc:101598	zgc:101598	0.012
prim1	primase polypeptide 1	0.012
ccne	cyclin E	0.012
mab21l1	mab-21-like 1	0.012
crkl	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.012
celsr3	cadherin, EGF LAG seven-pass G-type receptor 3	0.011
wdr82	WD repeat domain containing 82	0.011
mapk3	mitogen-activated protein kinase 3	0.011
zgc:113183	zgc:113183	0.011
dnm1l	dynamin 1-like	0.011
srsf6b	serine/arginine-rich splicing factor 6b	0.011
gins2	GINS complex subunit 2	0.011
gins3	GINS complex subunit 3	0.011
wdhd1	WD repeat and HMG-box DNA binding protein 1	0.010
sae1	SUMO1 activating enzyme subunit 1	0.010
rtkn2	rhotekin 2	0.010
tardbpl	TAR DNA binding protein, like	0.010
tgfb3	transforming growth factor, beta 3	0.010
zc3h13	zinc finger CCCH-type containing 13	0.010