Danio rerio

0 known processes

mc5ra

melanocortin 5a receptor

(Aliases: mc5ar,mc5rb,zMC5a)

mc5ra biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of camp biosynthetic process GO:0030819 2 0.926
Human Zebrafish
positive regulation of camp metabolic process GO:0030816 2 0.619
Human Zebrafish
energy homeostasis GO:0097009 3 0.471
Zebrafish
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.457
Human Zebrafish
negative regulation of feeding behavior GO:2000252 2 0.369
Zebrafish
positive regulation of purine nucleotide biosynthetic process GO:1900373 8 0.337
Human Zebrafish
embryonic organ development GO:0048568 381 0.216
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.183
Human Zebrafish
regulation of biosynthetic process GO:0009889 250 0.152
Human Zebrafish
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.144
Human Zebrafish
embryonic organ morphogenesis GO:0048562 274 0.137
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.118
Human Zebrafish
regulation of response to stimulus GO:0048583 269 0.112
Zebrafish
negative regulation of biological process GO:0048519 304 0.112
Zebrafish
synaptic transmission GO:0007268 35 0.105
homeostatic process GO:0042592 142 0.101
Zebrafish
digestive tract development GO:0048565 265 0.100
regulation of metabolic process GO:0019222 359 0.091
Human Zebrafish
carbohydrate derivative biosynthetic process GO:1901137 43 0.090
Human Zebrafish
regulation of multicellular organism growth GO:0040014 4 0.087
cell surface receptor signaling pathway GO:0007166 325 0.083
Zebrafish
convergent extension involved in gastrulation GO:0060027 71 0.080
positive regulation of purine nucleotide metabolic process GO:1900544 9 0.075
Human Zebrafish
organonitrogen compound metabolic process GO:1901564 74 0.073
Human Zebrafish
developmental growth involved in morphogenesis GO:0060560 86 0.071
multicellular organism growth GO:0035264 4 0.071
regulation of phosphorus metabolic process GO:0051174 43 0.068
Human Zebrafish
axon extension GO:0048675 45 0.066
regulation of nucleotide biosynthetic process GO:0030808 15 0.066
Human Zebrafish
melanin metabolic process GO:0006582 2 0.065
negative regulation of behavior GO:0048521 6 0.064
Zebrafish
larval development GO:0002164 2 0.064
synaptic transmission cholinergic GO:0007271 4 0.063
camp biosynthetic process GO:0006171 11 0.063
Human Zebrafish
cellular nitrogen compound biosynthetic process GO:0044271 218 0.061
Human Zebrafish
organic substance biosynthetic process GO:1901576 289 0.056
Human Zebrafish
cellular biosynthetic process GO:0044249 286 0.055
Human Zebrafish
embryonic skeletal system development GO:0048706 97 0.054
negative regulation of small gtpase mediated signal transduction GO:0051058 1 0.053
signal transduction GO:0007165 455 0.050
Zebrafish
regulation of protein transport GO:0051223 3 0.049
organonitrogen compound biosynthetic process GO:1901566 47 0.049
Human Zebrafish
antimicrobial humoral response GO:0019730 2 0.048
adult behavior GO:0030534 2 0.048
regulation of blood pressure GO:0008217 1 0.047
aging GO:0007568 2 0.047
regulation of establishment of protein localization GO:0070201 4 0.047
regulation of protein complex assembly GO:0043254 3 0.046
cyclic purine nucleotide metabolic process GO:0052652 18 0.044
Human Zebrafish
neuron neuron synaptic transmission GO:0007270 1 0.044
gland development GO:0048732 143 0.044
specification of symmetry GO:0009799 204 0.043
regulation of camp metabolic process GO:0030814 9 0.043
Human Zebrafish
response to chemical GO:0042221 320 0.042
regulation of cell communication GO:0010646 232 0.042
cellular macromolecule metabolic process GO:0044260 391 0.042
skeletal system development GO:0001501 181 0.041
cytoskeleton organization GO:0007010 96 0.041
organic cyclic compound metabolic process GO:1901360 301 0.041
Human Zebrafish
transport GO:0006810 220 0.040
energy reserve metabolic process GO:0006112 2 0.040
Zebrafish
chordate embryonic development GO:0043009 271 0.040
response to organic substance GO:0010033 153 0.039
purine containing compound metabolic process GO:0072521 29 0.038
Human Zebrafish
generation of neurons GO:0048699 385 0.038
neuropeptide signaling pathway GO:0007218 11 0.037
determination of bilateral symmetry GO:0009855 204 0.037
macromolecule modification GO:0043412 111 0.037
biosynthetic process GO:0009058 294 0.037
Human Zebrafish
organelle organization GO:0006996 227 0.037
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.037
Human Zebrafish
exocytosis GO:0006887 1 0.035
positive regulation of biosynthetic process GO:0009891 68 0.034
Human Zebrafish
membrane repolarization GO:0086009 2 0.034
neuron projection extension GO:1990138 45 0.034
small molecule metabolic process GO:0044281 77 0.034
Human Zebrafish
cyclic nucleotide biosynthetic process GO:0009190 18 0.034
Human Zebrafish
developmental growth GO:0048589 166 0.033
regulation of primary metabolic process GO:0080090 311 0.033
Human Zebrafish
cellular component movement GO:0006928 335 0.033
positive regulation of cellular biosynthetic process GO:0031328 68 0.033
Human Zebrafish
nitrogen compound metabolic process GO:0006807 319 0.033
Human Zebrafish
otic vesicle development GO:0071599 42 0.033
protein polymerization GO:0051258 4 0.033
immune system process GO:0002376 241 0.032
single organism localization GO:1902578 225 0.032
secondary metabolic process GO:0019748 3 0.031
positive regulation of cell cycle GO:0045787 3 0.031
single organism transport GO:0044765 206 0.031
phosphate containing compound metabolic process GO:0006796 108 0.030
Human Zebrafish
endocrine system development GO:0035270 65 0.030
tube morphogenesis GO:0035239 349 0.030
positive regulation of biological process GO:0048518 253 0.029
Human Zebrafish
negative regulation of response to stimulus GO:0048585 104 0.029
Zebrafish
sensory organ development GO:0007423 393 0.029
single organism biosynthetic process GO:0044711 71 0.028
Human Zebrafish
single organism metabolic process GO:0044710 217 0.028
Human Zebrafish
purine containing compound biosynthetic process GO:0072522 20 0.028
Human Zebrafish
heterocycle metabolic process GO:0046483 290 0.028
Human Zebrafish
microtubule polymerization GO:0046785 2 0.027
phenol containing compound biosynthetic process GO:0046189 4 0.027
regulation of protein polymerization GO:0032271 2 0.027
regulation of signaling GO:0023051 235 0.027
regulation of multicellular organismal process GO:0051239 277 0.027
microtubule based process GO:0007017 60 0.027
carbohydrate derivative metabolic process GO:1901135 61 0.026
Human Zebrafish
embryo development ending in birth or egg hatching GO:0009792 271 0.025
gastrulation GO:0007369 208 0.025
regulation of anterior head development GO:2000742 2 0.025
regulation of cellular protein metabolic process GO:0032268 52 0.025
positive regulation of metabolic process GO:0009893 108 0.025
Human Zebrafish
cellular nitrogen compound metabolic process GO:0034641 290 0.024
Human Zebrafish
regulation of nitrogen compound metabolic process GO:0051171 251 0.024
Human Zebrafish
central nervous system development GO:0007417 387 0.024
rna metabolic process GO:0016070 219 0.024
axon guidance GO:0007411 86 0.023
morphogenesis of an epithelium GO:0002009 333 0.023
regionalization GO:0003002 274 0.023
reflex GO:0060004 2 0.023
macromolecule localization GO:0033036 54 0.023
purine nucleotide biosynthetic process GO:0006164 20 0.022
Human Zebrafish
bmp signaling pathway involved in mesodermal cell fate specification GO:0060803 1 0.022
positive regulation of transport GO:0051050 2 0.022
aromatic compound biosynthetic process GO:0019438 217 0.022
Human Zebrafish
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.022
Human Zebrafish
carboxylic acid metabolic process GO:0019752 22 0.022
negative regulation of multicellular organismal process GO:0051241 69 0.022
cell motility GO:0048870 244 0.022
negative regulation of cellular process GO:0048523 283 0.022
regulation of phosphate metabolic process GO:0019220 43 0.021
Human Zebrafish
protein secretion GO:0009306 1 0.021
regulation of macromolecule metabolic process GO:0060255 317 0.021
positive regulation of protein polymerization GO:0032273 2 0.021
regulation of signal transduction GO:0009966 225 0.021
apoptotic process involved in development GO:1902742 2 0.021
cell migration involved in gastrulation GO:0042074 79 0.021
striated muscle cell development GO:0055002 108 0.021
centrosome organization GO:0051297 1 0.021
neuron differentiation GO:0030182 353 0.021
nucleobase containing compound biosynthetic process GO:0034654 205 0.020
Human Zebrafish
locomotion GO:0040011 313 0.020
single organism cellular localization GO:1902580 46 0.020
regulation of microtubule cytoskeleton organization GO:0070507 3 0.020
eye development GO:0001654 277 0.020
digestive tract morphogenesis GO:0048546 231 0.020
nucleobase containing compound metabolic process GO:0006139 274 0.020
Human Zebrafish
positive regulation of cellular process GO:0048522 201 0.020
Human Zebrafish
cell cell signaling GO:0007267 52 0.019
regulation of cellular component organization GO:0051128 86 0.019
striated muscle tissue development GO:0014706 110 0.019
cellular component biogenesis GO:0044085 178 0.019
chondrocyte intercalation involved in growth plate cartilage morphogenesis GO:0003428 1 0.019
system process GO:0003008 185 0.019
cartilage development GO:0051216 96 0.018
developmental cell growth GO:0048588 52 0.018
compound eye development GO:0048749 2 0.018
myofibril assembly GO:0030239 48 0.018
neuromuscular synaptic transmission GO:0007274 2 0.018
maintenance of location GO:0051235 4 0.018
response to oxygen containing compound GO:1901700 55 0.018
camp metabolic process GO:0046058 11 0.018
Human Zebrafish
renal system process involved in regulation of blood volume GO:0001977 1 0.018
response to other organism GO:0051707 97 0.018
axonogenesis GO:0007409 152 0.018
cognition GO:0050890 1 0.018
cell projection organization GO:0030030 284 0.018
determination of left right symmetry GO:0007368 179 0.017
phosphorus metabolic process GO:0006793 109 0.017
Human Zebrafish
convergent extension GO:0060026 118 0.017
regulation of circadian rhythm GO:0042752 4 0.017
germ line stem cell maintenance GO:0030718 2 0.017
regulation of neuron differentiation GO:0045664 56 0.017
localization of cell GO:0051674 244 0.017
connective tissue development GO:0061448 99 0.017
tissue remodeling GO:0048771 4 0.017
regulation of jak stat cascade GO:0046425 3 0.017
regulation of cellular biosynthetic process GO:0031326 245 0.016
Human Zebrafish
cellular protein modification process GO:0006464 100 0.016
brain development GO:0007420 293 0.016
regulation of cellular metabolic process GO:0031323 320 0.016
Human Zebrafish
protein localization GO:0008104 40 0.016
cell part morphogenesis GO:0032990 246 0.016
ear development GO:0043583 127 0.016
regulation of cytokine production GO:0001817 3 0.016
chemical homeostasis GO:0048878 49 0.016
positive regulation of cell adhesion GO:0045785 1 0.016
regulation of developmental process GO:0050793 247 0.016
gtp metabolic process GO:0046039 4 0.016
nucleotide metabolic process GO:0009117 28 0.016
Human Zebrafish
positive regulation of protein complex assembly GO:0031334 2 0.016
regulation of localization GO:0032879 104 0.016
carbohydrate homeostasis GO:0033500 1 0.016
cellular response to chemical stimulus GO:0070887 157 0.015
heart development GO:0007507 313 0.015
organic cyclic compound biosynthetic process GO:1901362 223 0.015
Human Zebrafish
microtubule polymerization or depolymerization GO:0031109 3 0.015
regulation of nucleocytoplasmic transport GO:0046822 2 0.015
phagocytosis GO:0006909 3 0.015
transcription from rna polymerase ii promoter GO:0006366 80 0.015
regulation of neurogenesis GO:0050767 87 0.015
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.015
Human Zebrafish
positive regulation of macromolecule metabolic process GO:0010604 93 0.015
cellular response to reactive oxygen species GO:0034614 2 0.014
camera type eye development GO:0043010 222 0.014
embryonic cranial skeleton morphogenesis GO:0048701 90 0.014
nucleic acid templated transcription GO:0097659 181 0.014
protein modification process GO:0036211 100 0.014
establishment of localization GO:0051234 244 0.014
kidney development GO:0001822 92 0.014
cell morphogenesis GO:0000902 289 0.014
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.014
neuron projection morphogenesis GO:0048812 161 0.013
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.013
cell migration GO:0016477 237 0.013
stem cell development GO:0048864 82 0.013
sensory perception of chemical stimulus GO:0007606 3 0.013
behavior GO:0007610 74 0.013
Zebrafish
regulation of anatomical structure morphogenesis GO:0022603 130 0.013
organophosphate biosynthetic process GO:0090407 23 0.013
Human Zebrafish
g protein coupled receptor signaling pathway GO:0007186 74 0.013
Zebrafish
heterocycle biosynthetic process GO:0018130 215 0.013
Human Zebrafish
cellular aromatic compound metabolic process GO:0006725 295 0.013
Human Zebrafish
neurological system process GO:0050877 62 0.013
vasculature development GO:0001944 278 0.013
ion homeostasis GO:0050801 41 0.013
multi organism process GO:0051704 134 0.013
skeletal system morphogenesis GO:0048705 102 0.013
negative regulation of ras protein signal transduction GO:0046580 1 0.013
cell morphogenesis involved in differentiation GO:0000904 195 0.013
cell growth GO:0016049 57 0.013
response to growth factor GO:0070848 39 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 5 0.013
regulation of sequestering of calcium ion GO:0051282 4 0.013
establishment of localization in cell GO:0051649 77 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.012
neuron development GO:0048666 262 0.012
thrombocyte differentiation GO:0002574 4 0.012
cell proliferation GO:0008283 80 0.012
metal ion homeostasis GO:0055065 26 0.012
cell cycle GO:0007049 93 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
heart contraction GO:0060047 71 0.012
regulation of cytoplasmic transport GO:1903649 4 0.012
convergent extension involved in organogenesis GO:0060029 10 0.012
protein metabolic process GO:0019538 183 0.012
regulation of cell differentiation GO:0045595 142 0.012
cellular amine metabolic process GO:0044106 2 0.012
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.012
morphogenesis of an epithelial sheet GO:0002011 49 0.012
blood vessel development GO:0001568 246 0.012
regulation of intracellular signal transduction GO:1902531 57 0.012
divalent inorganic cation homeostasis GO:0072507 22 0.012
anterior head development GO:0097065 2 0.012
regulation of systemic arterial blood pressure GO:0003073 1 0.012
regulation of cell cycle GO:0051726 52 0.012
positive regulation of secretion GO:0051047 1 0.012
embryonic heart tube morphogenesis GO:0003143 108 0.012
positive regulation of cellular component biogenesis GO:0044089 3 0.011
regulation of transport GO:0051049 45 0.011
circulatory system process GO:0003013 87 0.011
i kappab kinase nf kappab signaling GO:0007249 4 0.011
guanosine containing compound catabolic process GO:1901069 2 0.011
regulation of inflammatory response GO:0050727 2 0.011
protein phosphorylation GO:0006468 47 0.011
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.011
ovulation cycle process GO:0022602 2 0.011
positive regulation of cellular catabolic process GO:0031331 3 0.011
stem cell maintenance GO:0019827 4 0.011
cellular response to stress GO:0033554 62 0.011
pectoral fin development GO:0033339 50 0.011
single organism organelle organization GO:1902589 199 0.011
angiogenesis GO:0001525 158 0.011
cell fate commitment GO:0045165 99 0.011
cellular response to external stimulus GO:0071496 2 0.011
muscle tissue development GO:0060537 110 0.011
cellular response to lipid GO:0071396 39 0.011
regulation of reproductive process GO:2000241 4 0.011
regulation of rna metabolic process GO:0051252 224 0.011
cellular component assembly GO:0022607 170 0.010
negative regulation of protein phosphorylation GO:0001933 4 0.010
embryonic skeletal system morphogenesis GO:0048704 93 0.010
hatching GO:0035188 4 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.010
negative regulation of cell communication GO:0010648 96 0.010
epithelial cell proliferation involved in liver morphogenesis GO:0072575 2 0.010
positive regulation of immune effector process GO:0002699 3 0.010
response to endogenous stimulus GO:0009719 83 0.010
transcription dna templated GO:0006351 181 0.010
catechol containing compound biosynthetic process GO:0009713 2 0.010
ion transport GO:0006811 114 0.010
regulation of extent of cell growth GO:0061387 29 0.010

mc5ra disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
connective tissue disease DOID:65 0 0.011
musculoskeletal system disease DOID:17 0 0.011
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
disease of anatomical entity DOID:7 0 0.011