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Danio rerio

10 genes annotated in zebrafish

convergent extension involved in organogenesis

The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "convergent extension involved in organogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "convergent extension involved in organogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
gata2a	GATA-binding protein 2a	0.907	Zebrafish
mespa	mesoderm posterior a	0.736	Mouse
tfap2a	transcription factor AP-2 alpha	0.596
axin1	axin 1	0.459
slit1b	slit homolog 1b (Drosophila)	0.450	Zebrafish
tal1	T-cell acute lymphocytic leukemia 1	0.402
lfng	lunatic fringe homolog	0.385
foxd3	forkhead box D3	0.372
sox19b	SRY-box containing gene 19b	0.293	Zebrafish
hhex	hematopoietically expressed homeobox	0.261
sfrp1a	secreted frizzled-related protein 1a	0.260
tbx16	T-box gene 16	0.243
eya1	eyes absent homolog 1	0.238
lmo2	LIM domain only 2 (rhombotin-like 1)	0.236
rag2	recombination activating gene 2	0.229
nkx1.2la	NK1 transcription factor related 2-like,a	0.228
notch3	notch homolog 3	0.223
flh	floating head	0.221
lama2	laminin, alpha 2	0.209
znf503	zinc finger protein 503	0.204
neurod2	neurogenic differentiation 2	0.195
robo3	roundabout homolog 3	0.186	Zebrafish
si:ch211-235f6.2	si:ch211-235f6.2	0.163
igf1ra	insulin-like growth factor 1a receptor	0.154
apc	adenomatosis polyposis coli	0.152
gli1	GLI-Kruppel family member 1	0.151
ctsl1b	cathepsin L, 1 b	0.146
hlxb9la	homeo box HB9 like a	0.137
hoxb3a	homeo box B3a	0.136
arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.132
gata5	GATA-binding protein 5	0.123
pcdh8	protocadherin 8	0.122
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.121
six3a	sine oculis homeobox homolog 3a	0.117
ndr2	nodal-related 2	0.116
isl1	islet1	0.115
wnt3	wingless-type MMTV integration site family, member 3	0.114
wu:fv91b12	wu:fv91b12	0.109
wu:fb17g07	wu:fb17g07	0.105
sesn1	sestrin 1	0.100
hmgb1a	high-mobility group box 1a	0.099
pnx	posterior neuron-specific homeobox	0.095
fli1a	friend leukemia integration 1a	0.085
robo2	roundabout homolog 2	0.084	Zebrafish
foxb1.2	forkhead box B1.2	0.084
runx2b	runt-related transcription factor 2b	0.082
sox32	SRY-box containing gene 32	0.080
slc6a8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.078
lhx1b	LIM homeobox 1b	0.077
slit1a	slit homolog 1a (Drosophila)	0.077	Zebrafish
pitx2	paired-like homeodomain transcription factor 2	0.076
insm1b	insulinoma-associated 1b	0.076
tbx6	T-box gene 6	0.075
irx2a	iroquois homeobox protein 2, a	0.075
gata6	GATA-binding protein 6	0.075
runx2a	runt-related transcription factor 2a	0.070
irf6	interferon regulatory factor 6	0.070
ifnphi1	interferon phi 1	0.069
six4b	sine oculis homeobox homolog 4b	0.068
cc2d2a	coiled-coil and C2 domain containing 2A	0.067
coe2	coe2	0.067
irx5a	iroquois homeobox protein 5a	0.065
gata3	GATA-binding protein 3	0.065	Zebrafish
nkd2	naked cuticle homolog 2 and naked 2a	0.065
robo1	roundabout homolog 1	0.064
otx1b	orthodenticle homolog 1b	0.063
nphs2	nephrosis 2, idiopathic, steroid-resistant (podocin)	0.062
mespb	mesoderm posterior b	0.062	Mouse
neurod4	neurogenic differentiation 4	0.060
isl2a	islet2a	0.060
musk	muscle, skeletal, receptor tyrosine kinase	0.060
ptprf	protein tyrosine phosphatase, receptor type, F	0.060
ihhb	Indian hedgehog homolog b	0.059
lhx3	LIM homeobox 3	0.059
lingo1b	leucine rich repeat and Ig domain containing 1b	0.057
zic2a	zic family member 2 (odd-paired homolog, Drosophila), a	0.056
tcf12	transcription factor 12	0.055
znf703	zinc finger protein 703	0.054
wnt9b	wingless-type MMTV integration site family, member 9B	0.054
sox4b	SRY-box containing gene 4b	0.054
vangl2	vang-like 2 (van gogh, Drosophila)	0.052
id2a	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a	0.052
bmp2a	bone morphogenetic protein 2a	0.051
rx3	retinal homeobox gene 3	0.051
tbx24	T-box 24	0.051
lft1	lefty1	0.046
kdr	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.044
foxg1a	forkhead box G1a	0.044
pcdh10b	protocadherin 10b	0.044
sox17	SRY-box containing gene 17	0.044	Zebrafish
her7	hairy and enhancer of split related-7	0.043
sox10	SRY-box containing gene 10	0.043
mxtx2	mix-type homeobox gene 2	0.043
mpll	myeloproliferative leukemia virus oncogene, like	0.042
map2k4a	mitogen-activated protein kinase kinase 4a	0.042
aldh1l1	aldehyde dehydrogenase 1 family, member L1	0.042
foxa3	forkhead box A3	0.042
plp1a	proteolipid protein 1a	0.041
epha4b	eph receptor A4b	0.041
dbx1a	developing brain homeobox 1a	0.040
ntn1a	netrin 1a	0.040
amotl2a	angiomotin like 2a	0.039
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.039
eaf2	ELL associated factor 2	0.039
wnt7bb	wingless-type MMTV integration site family, member 7Bb	0.038
hbbe1.1	hemoglobin beta embryonic-1.1	0.037
m6pr	mannose-6-phosphate receptor (cation dependent)	0.036
rarab	retinoic acid receptor, alpha b	0.036
nadl1.2	neural adhesion molecule L1.2	0.035
alpi	alkaline phosphatase, intestinal	0.035
tnfsf10l3	tumor necrosis factor (ligand) superfamily, member 10 like 3	0.035
foxd5	forkhead box D5	0.034
kdrl	kinase insert domain receptor like	0.034
ntrk3b	neurotrophic tyrosine kinase, receptor, type 3b	0.034
wnt4b	wingless-type MMTV integration site family, member 4b	0.034
wnt7ba	wingless-type MMTV integration site family, member 7Ba	0.033
hbae1	hemoglobin alpha embryonic-1	0.033
irx1b	iroquois homeobox protein 1, b	0.033
hey1	hairy/enhancer-of-split related with YRPW motif 1	0.033
zic1	zic family member 1 (odd-paired homolog, Drosophila)	0.033
mesp2	mesoderm posterior 2 homolog (mouse)	0.032
tfap2b	transcription factor AP-2 beta	0.032
foxa1	forkhead box A1	0.032
ptprsa	protein tyrosine phosphatase, receptor type, s, a	0.032
tfr1a	transferrin receptor 1a	0.031
lhx5	LIM homeobox 5	0.031
ache	acetylcholinesterase	0.031
chrna1	cholinergic receptor, nicotinic, alpha polypeptide 1	0.030
wnt4a	wingless-type MMTV integration site family, member 4a	0.030
arhgef7b	Rho guanine nucleotide exchange factor (GEF) 7b	0.030
hoxd3a	homeo box D3a	0.029
vegfaa	vascular endothelial growth factor Aa	0.029
elk4	ELK4, ETS-domain protein	0.029
bmp7a	bone morphogenetic protein 7a	0.028
auts2	autism susceptibility candidate 2	0.028
axin2	axin 2 (conductin, axil)	0.028
trim71	tripartite motif-containing 71	0.028
og9x	OG9 homeobox gene	0.027
pax7a	paired box gene 7a	0.027
sp5l	Sp5 transcription factor-like	0.027
prdm14	PR domain containing 14	0.027
pld1a	phospholipase D1a	0.026
shha	sonic hedgehog a	0.026
tuba1l	tubulin, alpha 1, like	0.026
lft2	lefty2	0.026
setd8a	SET domain containing (lysine methyltransferase) 8a	0.025
runx3	runt-related transcription factor 3	0.025
hdac4	histone deacetylase 4	0.025
efnb1	ephrin B1	0.025
etv2	ets variant gene 2	0.025
runx1	runt-related transcription factor 1	0.024
cdx4	caudal type homeo box transcription factor 4	0.024
arx	aristaless related homeobox	0.024
wif1	wnt inhibitory factor 1	0.024
sulf2	sulfatase 2	0.023
chrnb3b	cholinergic receptor, nicotinic, beta polypeptide 3b	0.023	Zebrafish
tp63	tumor protein p63	0.023
hbae3	hemoglobin alpha embryonic-3	0.023
foxc1a	forkhead box C1a	0.023
dab1a	disabled homolog 1a (Drosophila)	0.023
per3	period homolog 3 (Drosophila)	0.022
hoxb2a	homeo box B2a	0.022
igf1	insulin-like growth factor 1	0.022
ikzf5	IKAROS family zinc finger 5	0.022
neurog3	neurogenin 3	0.022
ripply2	ripply2	0.021
fign	fidgetin	0.021
pth2r	parathyroid hormone 2 receptor	0.021
kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.021
zeb2a	zinc finger E-box binding homeobox 2a	0.021
stac3	SH3 and cysteine rich domain 3	0.021
igfbp3	insulin-like growth factor binding protein 3	0.021
drl	draculin	0.021
foxe3	forkhead box E3	0.020
hnf1ba	HNF1 homeobox Ba	0.020
postn	periostin, osteoblast specific factor	0.020
wnt11	wingless-type MMTV integration site family, member 11	0.020
sox3	SRY-box containing gene 3	0.020	Zebrafish
piwil2	piwi-like 2 (Drosophila)	0.020
scd	stearoyl-CoA desaturase (delta-9-desaturase)	0.020
eml2	echinoderm microtubule associated protein like 2	0.020
disc1	disrupted in schizophrenia 1	0.020
nr2f1a	nuclear receptor subfamily 2, group F, member 1a	0.019
dlx3b	distal-less homeobox gene 3b	0.019
tsga14	testis specific, 14	0.019
hmx4	H6 family homeobox 4	0.019
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.018
hoxb5b	homeo box B5b	0.018
prl	prolactin	0.018
nkx2.1b	NK2 homeobox 1b	0.018
fzd8b	frizzled homolog 8b	0.018
angpt1	angiopoietin 1	0.018
nrp2a	neuropilin 2a	0.018
atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.017
foxp2	forkhead box P2	0.017
gsc	goosecoid	0.017
chd	chordin	0.017
nrp1a	neuropilin 1a	0.017
siah2l	seven in absentia homolog 2 (Drosophila)-like	0.017
egr1	early growth response 1	0.017
si:dkeyp-104h9.6	si:dkeyp-104h9.6	0.017
epb4.1l4	erythrocyte protein band 4.1-like 4	0.017
kirrel3l	kin of IRRE like 3 like	0.017
notch1a	notch homolog 1a	0.017
dag1	dystroglycan 1	0.017
flot1	flotillin 1	0.017
ca16b	carbonic anhydrase XVI b	0.016
her5	hairy-related 5	0.016
kdm5c	lysine (K)-specific demethylase 5C	0.016
tshb	thyroid stimulating hormone, beta subunit	0.016
hoxb5a	homeo box B5a	0.016
nr2f2	nuclear receptor subfamily 2, group F, member 2	0.016
ret1	receptor tyrosine kinase	0.016
gfi1.1	growth factor independent 1.1	0.016
otx2	orthodenticle homolog 2	0.016
tbpl2	TATA box binding protein like 2	0.016
zgc:64114	zgc:64114	0.016
src	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.016
ca7	carbonic anhydrase VII	0.016
ptges3a	prostaglandin E synthase 3a (cytosolic)	0.016
ahctf1	AT hook containing transcription factor 1	0.015
pax6a	paired box gene 6a	0.015
top2b	topoisomerase (DNA) II beta	0.015
col2a1a	collagen type II, alpha-1a	0.015
dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)	0.015
cyfip2	cytoplasmic FMR1 interacting protein 2	0.015
or115-15	odorant receptor, family F, subfamily 115, member 15	0.015
hoxa3a	homeo box A3a	0.015
chrna2a	cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)	0.015	Zebrafish
gbx2	gastrulation brain homeo box 2	0.014
dlb	deltaB	0.014
ephb3a	eph receptor B3a	0.014
dixdc1a	DIX domain containing 1a	0.014
camkvb	CaM kinase-like vesicle-associated b	0.014
fas	Fas (TNF receptor superfamily, member 6)	0.014
fkbp10	FK506 binding protein 10	0.014
cdk8	cyclin-dependent kinase 8	0.014
yaf2	YY1 associated factor 2	0.014
lhx1a	LIM homeobox 1a	0.014
dvl3	dishevelled, dsh homolog 3 (Drosophila)	0.014
pou4f2	POU domain, class 4, transcription factor 2	0.014
six1b	sine oculis homeobox homolog 1b	0.014
sox9a	SRY-box containing gene 9a	0.014	Zebrafish
slc12a2	solute carrier family 12 (potassium/chloride transporters), member 2	0.014
vwf	von Willebrand factor	0.014
foxh1	forkhead box H1	0.014
extl3	exostoses (multiple)-like 3	0.014
evx2	even-skipped homeobox 2	0.014
fryl	furry homolog-like (Drosophila)	0.014
plce1	phospholipase C, epsilon 1	0.014
si:ch211-255l12.1	si:ch211-255l12.1	0.013
has2	hyaluronan synthase 2	0.013
tcf7l1a	transcription factor 7-like 1a (T-cell specific, HMG-box)	0.013
gng3	guanine nucleotide binding protein (G protein), gamma 3	0.013
cryaba	crystallin, alpha B, a	0.013
zeb1	zinc finger E-box binding homeobox 1	0.013
sox11a	SRY-box containing gene 11a	0.013
fzd5	frizzled homolog 5	0.013
evx1	even-skipped homeobox 1	0.013
zic3	zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)	0.013
spon2a	spondin 2a, extracellular matrix protein	0.013
tfap2c	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.013
igf1rb	insulin-like growth factor 1b receptor	0.013
LOC100000500	sclerostin-like	0.013
ccne	cyclin E	0.013
rspo3	R-spondin 3 homolog (Xenopus laevis)	0.013
chrna7	cholinergic receptor, nicotinic, alpha polypeptide 7	0.013	Zebrafish
tll1	tolloid-like 1	0.013
hif1an	hypoxia-inducible factor 1, alpha subunit inhibitor	0.013
irx7	iroquois homeobox protein 7	0.013
cd99l2	CD99 antigen-like 2	0.013
eaf1	ELL associated factor 1	0.013
irx4b	iroquois homeobox protein 4b	0.013
admp	anti-dorsalizing morphogenic protein	0.013
spaw	southpaw	0.012
sox2	SRY-box containing gene 2	0.012	Zebrafish
foxi1	forkhead box I1	0.012
klf4	Kruppel-like factor 4	0.012
glra4a	glycine receptor, alpha 4a	0.012
zic2b	zic family member 2 (odd-paired homolog, Drosophila) b	0.012
bcl2	B-cell leukemia/lymphoma 2	0.012
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.012
snai1a	snail homolog 1a (Drosophila)	0.012
mc5ra	melanocortin 5a receptor	0.012
fbxw11a	F-box and WD-40 domain protein 11a	0.012
ripply1	ripply1	0.012
zgc:171553	zgc:171553	0.012
ntf7	neurotrophin 7	0.012
vent	ventral expressed homeobox	0.012
alas2	aminolevulinate, delta-, synthetase 2	0.012
chpf	chondroitin polymerizing factor	0.012
phc2	polyhomeotic-like 2 (Drosophila)	0.011
gbx1	gastrulation brain homeobox 1	0.011
zgc:92715	zgc:92715	0.011
lrrc6	leucine rich repeat containing 6	0.011
msxc	muscle segment homeobox C	0.011
pcdh18a	protocadherin 18a	0.011
zgc:103564	zgc:103564	0.011
has3	hyaluronan synthase 3	0.011
si:xx-bac7cse.2	si:xx-bac7cse.2	0.011
wu:fa07b03	wu:fa07b03	0.011
boc	brother of CDO	0.011
p2rx3a	purinergic receptor P2X, ligand-gated ion channel, 3a	0.011
meis3	myeloid ecotropic viral integration site 3	0.011
glud1a	glutamate dehydrogenase 1a	0.011
sept7b	septin 7b	0.011
prdm5	PR domain containing 5	0.011
ssbp3a	single stranded DNA binding protein 3a	0.011
sox19a	SRY-box containing gene 19a	0.011	Zebrafish
neo1	neogenin 1	0.011
nfatc4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.011
her1	hairy-related 1	0.011
si:ch211-262e15.1	si:ch211-262e15.1	0.011
tbx1	T-box 1	0.011
hapln1a	hyaluronan and proteoglycan link protein 1a	0.010
glra4b	glycine receptor, alpha 4b	0.010
nrxn1a	neurexin 1a	0.010
six4a	sine oculis homeobox homolog 4a	0.010
atp6ap2	ATPase, H+ transporting, lysosomal accessory protein 2	0.010
gatsl2	GATS protein-like 2	0.010
eif3hb	eukaryotic translation initiation factor 3, subunit H, b	0.010
kpna4	karyopherin alpha 4 (importin alpha 3)	0.010
glra1	glycine receptor, alpha 1	0.010
celsr1b	cadherin EGF LAG seven-pass G-type receptor 1b	0.010
myf5	myogenic factor 5	0.010
mc5rb	melanocortin 5b receptor	0.010