Danio rerio

17 known processes

pafah1b1a

platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a

pafah1b1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapsis GO:0007129 1 0.943
Worm
retrograde axon cargo transport GO:0008090 1 0.742
Mouse Fly
cell part morphogenesis GO:0032990 246 0.660
Human Rat Fly
cell projection organization GO:0030030 284 0.651
Human Rat Fly
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.635
Human Rat Fly
central nervous system neuron axonogenesis GO:0021955 18 0.616
Human
cell morphogenesis GO:0000902 289 0.581
Human Rat Fly
reciprocal dna recombination GO:0035825 1 0.578
Worm
pronuclear migration GO:0035046 1 0.571
Worm
cognition GO:0050890 1 0.549
Mouse
reciprocal meiotic recombination GO:0007131 1 0.529
Worm
neuron projection morphogenesis GO:0048812 161 0.514
Human Rat Fly
centrosome localization GO:0051642 1 0.504
Rat Fly
nuclear envelope organization GO:0006998 2 0.498
Mouse
axon extension GO:0048675 45 0.473
Rat
cellular component assembly GO:0022607 170 0.454
Mouse Worm Fly
forebrain cell migration GO:0021885 1 0.451
Mouse
cellular component morphogenesis GO:0032989 336 0.420
Human Mouse Rat Fly
regulation of axonogenesis GO:0050770 32 0.399
Rat
larval development GO:0002164 2 0.389
Worm
regulation of multicellular organismal development GO:2000026 223 0.375
Rat Fly
neurological system process GO:0050877 62 0.373
Human Mouse
centrosome cycle GO:0007098 1 0.372
Worm Fly
regulation of response to cytokine stimulus GO:0060759 3 0.369
Mouse
osteoclast differentiation GO:0030316 1 0.356
Mouse
spindle assembly GO:0051225 2 0.343
Worm Fly
neuroblast proliferation GO:0007405 2 0.337
Mouse Fly
organelle assembly GO:0070925 110 0.320
Mouse Worm Fly
cell projection morphogenesis GO:0048858 244 0.320
Human Rat Fly
cell morphogenesis involved in differentiation GO:0000904 195 0.307
Human Rat Fly
microtubule organizing center organization GO:0031023 1 0.302
Human Worm Fly
centrosome organization GO:0051297 1 0.301
Worm Fly
positive regulation of cell cycle GO:0045787 3 0.291
Rat
phagocytosis GO:0006909 3 0.282
Worm
negative regulation of biological process GO:0048519 304 0.266
Mouse Rat Fly
signal transduction GO:0007165 455 0.265
Mouse Fly
neuron neuron synaptic transmission GO:0007270 1 0.265
Worm
spermatid development GO:0007286 2 0.259
Mouse
fertilization GO:0009566 3 0.258
Worm
phagocytosis engulfment GO:0006911 1 0.256
Worm
central nervous system neuron differentiation GO:0021953 74 0.254
Human Rat
neuron differentiation GO:0030182 353 0.250
Human Rat Fly
axon cargo transport GO:0008088 2 0.242
Mouse Fly
cytoskeleton dependent intracellular transport GO:0030705 10 0.239
Mouse Fly
protein secretion GO:0009306 1 0.228
Mouse
axonogenesis GO:0007409 152 0.227
Human Rat Fly
stem cell proliferation GO:0072089 4 0.225
Mouse Fly
neuron projection development GO:0031175 180 0.224
Human Rat Fly
cellular component assembly involved in morphogenesis GO:0010927 107 0.224
Mouse Fly
nuclear migration GO:0007097 3 0.215
Rat Worm Fly
aging GO:0007568 2 0.215
organic cyclic compound biosynthetic process GO:1901362 223 0.214
axon guidance GO:0007411 86 0.214
Fly
regulation of rho protein signal transduction GO:0035023 2 0.207
Mouse
regulation of neuron differentiation GO:0045664 56 0.204
Rat Fly
chromosome organization involved in meiosis GO:0070192 1 0.197
Worm
cellular response to dna damage stimulus GO:0006974 24 0.193
regulation of microtubule based movement GO:0060632 3 0.186
Fly
response to oxidative stress GO:0006979 11 0.186
central nervous system development GO:0007417 387 0.180
regulation of axon extension GO:0030516 24 0.180
Rat
cell motility GO:0048870 244 0.179
Human Mouse Rat Fly
immune system process GO:0002376 241 0.179
Mouse
developmental cell growth GO:0048588 52 0.176
Rat
stem cell division GO:0017145 1 0.171
Rat
cellular biosynthetic process GO:0044249 286 0.171
Fly
taxis GO:0042330 109 0.167
Fly
central nervous system neuron development GO:0021954 29 0.165
Human
developmental growth involved in morphogenesis GO:0060560 86 0.165
Rat
membrane invagination GO:0010324 1 0.162
Worm
regulation of cell development GO:0060284 100 0.161
Rat Fly
biosynthetic process GO:0009058 294 0.160
Fly
system process GO:0003008 185 0.159
Human Mouse
regulation of gene expression GO:0010468 265 0.155
Fly
regulation of protein binding GO:0043393 3 0.151
nucleobase containing compound biosynthetic process GO:0034654 205 0.147
developmental growth GO:0048589 166 0.145
Rat
regulation of response to oxidative stress GO:1902882 2 0.144
small gtpase mediated signal transduction GO:0007264 8 0.141
myeloid cell differentiation GO:0030099 86 0.141
Mouse
actin filament based process GO:0030029 64 0.137
Mouse
regulation of nucleotide catabolic process GO:0030811 2 0.136
Mouse
apical protein localization GO:0045176 6 0.135
Zebrafish
synaptic vesicle localization GO:0097479 1 0.134
Worm
organelle organization GO:0006996 227 0.134
Human Mouse Worm Fly
intracellular mrna localization GO:0008298 1 0.133
Fly
cell growth GO:0016049 57 0.132
Rat
reproductive process GO:0022414 40 0.132
Mouse Worm Fly
regulation of response to stimulus GO:0048583 269 0.131
Mouse Fly
pyruvate metabolic process GO:0006090 1 0.130
establishment of localization GO:0051234 244 0.130
Human Zebrafish Mouse Rat Worm Fly
negative regulation of neuron differentiation GO:0045665 10 0.129
Rat
cellular component movement GO:0006928 335 0.128
Human Mouse Rat Worm Fly
regulation of neuron projection development GO:0010975 40 0.127
Rat Fly
negative regulation of cellular process GO:0048523 283 0.126
Mouse Rat Fly
central nervous system projection neuron axonogenesis GO:0021952 15 0.123
Human
regulation of reproductive process GO:2000241 4 0.121
cellular nitrogen compound biosynthetic process GO:0044271 218 0.121
neuron development GO:0048666 262 0.120
Human Rat Fly
rho protein signal transduction GO:0007266 5 0.120
growth GO:0040007 174 0.119
Rat
regulation of establishment of protein localization GO:0070201 4 0.118
neuron projection guidance GO:0097485 86 0.118
Fly
adult behavior GO:0030534 2 0.117
Human Mouse
synaptic vesicle transport GO:0048489 1 0.114
Worm
nucleic acid metabolic process GO:0090304 244 0.112
Worm
regulation of nucleic acid templated transcription GO:1903506 213 0.112
Fly
negative regulation of metabolic process GO:0009892 86 0.112
Mouse
forebrain development GO:0030900 96 0.109
Human Mouse Rat
positive regulation of neuron projection development GO:0010976 9 0.109
Rat
nitrogen compound metabolic process GO:0006807 319 0.109
Mouse Worm
regulation of metabolic process GO:0019222 359 0.108
Mouse Fly
regulation of extent of cell growth GO:0061387 29 0.107
Rat
locomotor rhythm GO:0045475 3 0.107
regulation of gtp catabolic process GO:0033124 2 0.106
Mouse
phosphorus metabolic process GO:0006793 109 0.106
Mouse
multicellular organism growth GO:0035264 4 0.106
response to chemical GO:0042221 320 0.105
Mouse Fly
response to abiotic stimulus GO:0009628 122 0.105
guanosine containing compound metabolic process GO:1901068 4 0.105
Mouse
axon development GO:0061564 166 0.105
Human Rat Fly
organic substance biosynthetic process GO:1901576 289 0.104
Fly
organelle fission GO:0048285 23 0.104
Worm
gtp metabolic process GO:0046039 4 0.103
Mouse
positive regulation of transport GO:0051050 2 0.103
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 38 0.102
Rat Fly
asymmetric protein localization GO:0008105 6 0.101
Zebrafish
cell death in response to oxidative stress GO:0036473 2 0.101
protein modification process GO:0036211 100 0.099
nuclear division GO:0000280 23 0.099
Worm
regulation of cellular component size GO:0032535 30 0.098
Rat
regulation of cellular response to oxidative stress GO:1900407 2 0.098
transport GO:0006810 220 0.095
Mouse Worm Fly
myeloid cell development GO:0061515 32 0.093
Mouse
microtubule based movement GO:0007018 33 0.093
Mouse Worm Fly
ameboidal type cell migration GO:0001667 143 0.093
Mouse Fly
regulation of neurogenesis GO:0050767 87 0.092
Rat Fly
positive regulation of map kinase activity GO:0043406 3 0.090
regulation of signal transduction GO:0009966 225 0.089
Mouse Fly
immune system development GO:0002520 191 0.088
Mouse
multicellular organismal signaling GO:0035637 22 0.088
Mouse
reproduction GO:0000003 40 0.088
Mouse Worm Fly
embryo development ending in birth or egg hatching GO:0009792 271 0.087
Worm
head development GO:0060322 303 0.087
lipid storage GO:0019915 1 0.086
regulation of cell cycle GO:0051726 52 0.086
Rat Fly
embryonic organ development GO:0048568 381 0.085
neuron projection extension GO:1990138 45 0.084
Rat
regulation of nervous system development GO:0051960 90 0.084
Rat Fly
regulation of purine nucleotide catabolic process GO:0033121 2 0.083
Mouse
negative regulation of gene expression GO:0010629 65 0.083
regulation of biological quality GO:0065008 263 0.083
Zebrafish Rat Fly
retina homeostasis GO:0001895 12 0.083
Zebrafish
regulation of transcription dna templated GO:0006355 213 0.083
Fly
negative regulation of neuron projection development GO:0010977 9 0.079
Rat
meiotic nuclear division GO:0007126 4 0.078
Worm
neuron migration GO:0001764 22 0.078
Human Mouse Rat
negative regulation of multicellular organismal process GO:0051241 69 0.078
Rat
regulation of rna biosynthetic process GO:2001141 213 0.077
Fly
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 2 0.077
negative regulation of protein transport GO:0051224 3 0.077
cellular protein metabolic process GO:0044267 129 0.076
Fly
regulation of signaling GO:0023051 235 0.076
Mouse Fly
small molecule metabolic process GO:0044281 77 0.075
Mouse
photoreceptor cell differentiation GO:0046530 55 0.075
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.074
Mouse Worm
positive regulation of neurogenesis GO:0050769 24 0.073
Rat
cell surface receptor signaling pathway GO:0007166 325 0.073
Mouse Fly
negative regulation of nervous system development GO:0051961 22 0.073
Rat
locomotion GO:0040011 313 0.072
Human Mouse Rat Worm Fly
autophagy GO:0006914 4 0.072
cilium assembly GO:0042384 58 0.072
regulation of developmental process GO:0050793 247 0.072
Rat Fly
heterocycle biosynthetic process GO:0018130 215 0.072
neural precursor cell proliferation GO:0061351 20 0.071
Mouse Fly
cilium organization GO:0044782 71 0.071
macromolecule biosynthetic process GO:0009059 227 0.071
Fly
single organism metabolic process GO:0044710 217 0.071
Mouse Worm
positive regulation of cellular process GO:0048522 201 0.070
Mouse Rat Fly
organic cyclic compound metabolic process GO:1901360 301 0.069
Mouse Worm
regulation of nitrogen compound metabolic process GO:0051171 251 0.069
Mouse Fly
cellular component biogenesis GO:0044085 178 0.068
Mouse Worm Fly
protein complex subunit organization GO:0071822 46 0.068
Worm Fly
developmental maturation GO:0021700 34 0.067
Fly
regulation of gtpase activity GO:0043087 2 0.066
Mouse
regulation of cellular biosynthetic process GO:0031326 245 0.066
Fly
heart development GO:0007507 313 0.065
response to stress GO:0006950 263 0.065
Mouse
glucose homeostasis GO:0042593 1 0.065
negative regulation of cell development GO:0010721 26 0.064
Rat
positive regulation of stem cell proliferation GO:2000648 1 0.063
negative regulation of cell projection organization GO:0031345 9 0.063
Rat
regulation of system process GO:0044057 40 0.062
regulation of protein transport GO:0051223 3 0.062
regulation of cell size GO:0008361 29 0.062
Rat
single organism behavior GO:0044708 24 0.061
Human Mouse
regulation of multicellular organismal process GO:0051239 277 0.061
Rat Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.061
Fly
establishment of cell polarity GO:0030010 18 0.061
Human Worm
organonitrogen compound metabolic process GO:1901564 74 0.059
Mouse
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 2 0.059
maintenance of location GO:0051235 4 0.059
cellular amine metabolic process GO:0044106 2 0.059
brain morphogenesis GO:0048854 18 0.058
female gamete generation GO:0007292 14 0.057
Fly
embryonic organ morphogenesis GO:0048562 274 0.057
positive regulation of nervous system development GO:0051962 25 0.056
Rat
cellular macromolecule metabolic process GO:0044260 391 0.056
Worm Fly
morphogenesis of an epithelium GO:0002009 333 0.055
enzyme linked receptor protein signaling pathway GO:0007167 106 0.055
Fly
neuromuscular process controlling balance GO:0050885 3 0.055
Human Mouse
neuromuscular process GO:0050905 7 0.054
Human Mouse
macroautophagy GO:0016236 1 0.053
single organism localization GO:1902578 225 0.053
Human Mouse Worm Fly
regulation of mitotic cell cycle phase transition GO:1901990 8 0.053
Fly
cilium morphogenesis GO:0060271 85 0.052
mitotic nuclear division GO:0007067 18 0.052
Worm
negative regulation of cell cycle process GO:0010948 9 0.052
Fly
regulation of meiotic cell cycle GO:0051445 1 0.052
regulation of neuron migration GO:2001222 2 0.051
limbic system development GO:0021761 16 0.048
Mouse
locomotory behavior GO:0007626 34 0.048
Human Mouse
synaptic transmission GO:0007268 35 0.047
Mouse Worm
cellular nitrogen compound metabolic process GO:0034641 290 0.047
Mouse Worm
brain development GO:0007420 293 0.046
amine metabolic process GO:0009308 2 0.045
organelle transport along microtubule GO:0072384 1 0.045
Mouse Fly
response to light stimulus GO:0009416 46 0.045
protein metabolic process GO:0019538 183 0.045
Fly
negative regulation of mitotic cell cycle phase transition GO:1901991 5 0.045
Fly
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.044
nucleic acid templated transcription GO:0097659 181 0.044
negative regulation of biosynthetic process GO:0009890 55 0.044
cellular aromatic compound metabolic process GO:0006725 295 0.044
Mouse Worm
extrinsic apoptotic signaling pathway GO:0097191 3 0.043
positive regulation of axon extension GO:0045773 5 0.043
Rat
ras protein signal transduction GO:0007265 7 0.043
response to external stimulus GO:0009605 264 0.043
Fly
multi organism process GO:0051704 134 0.043
Mouse Worm Fly
multicellular organismal response to stress GO:0033555 2 0.042
regulation of cellular metabolic process GO:0031323 320 0.041
Mouse Fly
cell migration GO:0016477 237 0.041
Human Mouse Rat Fly
chemotaxis GO:0006935 104 0.041
Fly
regulation of bmp signaling pathway GO:0030510 39 0.041
Fly
regulation of protein metabolic process GO:0051246 56 0.041
Fly
heart morphogenesis GO:0003007 156 0.040
carbohydrate homeostasis GO:0033500 1 0.040
cell cycle checkpoint GO:0000075 7 0.040
Fly
hydrogen peroxide metabolic process GO:0042743 2 0.040
positive regulation of secretion by cell GO:1903532 1 0.040
negative regulation of secretion GO:0051048 2 0.040
macromolecule localization GO:0033036 54 0.040
Zebrafish Mouse Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 50 0.040
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.040
Fly
bmp signaling pathway GO:0030509 52 0.039
Fly
axon midline choice point recognition GO:0016199 4 0.039
muscle cell cellular homeostasis GO:0046716 5 0.039
Fly
regulation of apoptotic process GO:0042981 98 0.039
sensory perception GO:0007600 39 0.039
regulation of synaptic plasticity GO:0048167 1 0.039
digestive tract morphogenesis GO:0048546 231 0.038
regulation of multicellular organism growth GO:0040014 4 0.038
behavior GO:0007610 74 0.038
Human Mouse
regulation of rna metabolic process GO:0051252 224 0.038
Fly
regulation of cell projection organization GO:0031344 44 0.038
Rat Fly
organic acid metabolic process GO:0006082 31 0.038
myeloid leukocyte differentiation GO:0002573 15 0.038
Mouse
single organism organelle organization GO:1902589 199 0.038
Human Mouse Worm Fly
regulation of cellular amine metabolic process GO:0033238 0 0.038
establishment of synaptic vesicle localization GO:0097480 1 0.037
Worm
transcription dna templated GO:0006351 181 0.037
homeostatic process GO:0042592 142 0.037
Zebrafish Fly
regionalization GO:0003002 274 0.037
Fly
positive regulation of signal transduction GO:0009967 56 0.037
Mouse
nucleocytoplasmic transport GO:0006913 4 0.036
somatic muscle development GO:0007525 4 0.036
cell aging GO:0007569 2 0.036
transmission of nerve impulse GO:0019226 19 0.036
Mouse
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.036
neuromuscular synaptic transmission GO:0007274 2 0.036
microtubule based transport GO:0010970 10 0.036
Mouse Fly
cellular amino acid metabolic process GO:0006520 7 0.035
regulation of molecular function GO:0065009 70 0.035
Mouse
regulation of protein complex assembly GO:0043254 3 0.035
negative chemotaxis GO:0050919 1 0.035
aromatic compound biosynthetic process GO:0019438 217 0.035
regulation of cellular component movement GO:0051270 55 0.035
Fly
positive regulation of neuron differentiation GO:0045666 12 0.035
Rat
single organism transport GO:0044765 206 0.035
Mouse Worm Fly
regulation of hydrolase activity GO:0051336 28 0.035
Mouse
regulation of rho gtpase activity GO:0032319 1 0.034
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.034
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 68 0.034
Fly
skeletal system development GO:0001501 181 0.034
membrane organization GO:0061024 21 0.034
Mouse Worm
response to radiation GO:0009314 51 0.034
single organism membrane organization GO:0044802 20 0.034
Mouse
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.034
regulation of stem cell proliferation GO:0072091 2 0.033
cellular carbohydrate metabolic process GO:0044262 4 0.033
regulation of protein ubiquitination GO:0031396 3 0.033
regulation of developmental growth GO:0048638 38 0.033
Rat
regulation of organelle organization GO:0033043 29 0.033
positive regulation of biological process GO:0048518 253 0.033
Mouse Rat Fly
cellular component disassembly GO:0022411 1 0.033
Mouse
tube morphogenesis GO:0035239 349 0.033
regulation of growth GO:0040008 42 0.033
Rat
regulation of binding GO:0051098 3 0.032
establishment of protein localization to organelle GO:0072594 4 0.032
gastrulation GO:0007369 208 0.031
regulation of oxidative stress induced cell death GO:1903201 2 0.031
synaptic growth at neuromuscular junction GO:0051124 2 0.031
regulation of anatomical structure morphogenesis GO:0022603 130 0.031
Rat Fly
chemosensory behavior GO:0007635 1 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.031
regulation of oocyte development GO:0060281 3 0.031
programmed cell death GO:0012501 119 0.031
regulation of receptor activity GO:0010469 2 0.031
heart contraction GO:0060047 71 0.031
positive regulation of neuron death GO:1901216 1 0.030
cell cycle GO:0007049 93 0.030
Human Rat Worm Fly
intracellular signal transduction GO:0035556 85 0.030
Mouse
dendrite morphogenesis GO:0048813 5 0.030
Fly
circulatory system process GO:0003013 87 0.030
positive regulation of multicellular organismal process GO:0051240 52 0.029
Rat
positive regulation of signaling GO:0023056 56 0.029
Mouse
cell division GO:0051301 20 0.029
Rat Fly
negative regulation of developmental process GO:0051093 65 0.029
Rat Fly
cell cell signaling GO:0007267 52 0.029
Mouse Worm
regulation of blood circulation GO:1903522 32 0.029
action potential GO:0001508 19 0.029
nuclear transport GO:0051169 4 0.028
rna biosynthetic process GO:0032774 181 0.028
regulation of primary metabolic process GO:0080090 311 0.028
Mouse Fly
cellular response to stress GO:0033554 62 0.028
Mouse
negative regulation of neurogenesis GO:0050768 20 0.028
Rat
regulation of intracellular protein transport GO:0033157 3 0.028
cell cycle process GO:0022402 53 0.028
Human Worm Fly
response to osmotic stress GO:0006970 11 0.028
actin cytoskeleton organization GO:0030036 63 0.028
Mouse
gtp catabolic process GO:0006184 2 0.028
Mouse
regulation of catalytic activity GO:0050790 55 0.028
Mouse
regulation of neural precursor cell proliferation GO:2000177 3 0.028
negative regulation of autophagy GO:0010507 1 0.028
regulation of macromolecule biosynthetic process GO:0010556 225 0.027
Fly
entrainment of circadian clock GO:0009649 2 0.027
response to decreased oxygen levels GO:0036293 25 0.027
mesenchymal cell development GO:0014031 78 0.027
positive regulation of catabolic process GO:0009896 4 0.027
carboxylic acid metabolic process GO:0019752 22 0.027
eye development GO:0001654 277 0.027
Fly
long chain fatty acid metabolic process GO:0001676 1 0.026
ribonucleoside triphosphate biosynthetic process GO:0009201 2 0.026
cellular response to nutrient levels GO:0031669 2 0.026
regulation of cell cycle phase transition GO:1901987 8 0.026
Fly
digestive tract development GO:0048565 265 0.026
regulation of nucleocytoplasmic transport GO:0046822 2 0.026
apoptotic signaling pathway GO:0097190 23 0.026
regulation of ras gtpase activity GO:0032318 2 0.026
Mouse
membrane fusion GO:0061025 2 0.026
mitotic cell cycle embryonic GO:0045448 2 0.026
death GO:0016265 121 0.026
multicellular organism reproduction GO:0032504 35 0.026
Mouse Fly
cellular localization GO:0051641 97 0.026
Human Zebrafish Mouse Rat Worm Fly
regulation of anatomical structure size GO:0090066 33 0.025
Rat
establishment of endothelial barrier GO:0061028 3 0.025
histone phosphorylation GO:0016572 2 0.025
sex determination GO:0007530 1 0.025
regulation of autophagy GO:0010506 3 0.025
macromolecular complex assembly GO:0065003 35 0.025
Worm Fly
mitotic cell cycle GO:0000278 64 0.024
Human Rat Worm Fly
viral process GO:0016032 1 0.024
regulation of cell shape GO:0008360 1 0.024
negative regulation of cell cycle phase transition GO:1901988 5 0.024
Fly
regulation of cellular response to stress GO:0080135 20 0.024
Mouse
stem cell development GO:0048864 82 0.024
Fly
myeloid cell homeostasis GO:0002262 56 0.024
sphingolipid biosynthetic process GO:0030148 2 0.024
chordate embryonic development GO:0043009 271 0.024
rna localization GO:0006403 4 0.024
Fly
female sex differentiation GO:0046660 4 0.024
cellular protein modification process GO:0006464 100 0.024
negative regulation of tor signaling GO:0032007 2 0.024
positive regulation of response to stimulus GO:0048584 80 0.023
Mouse
convergent extension GO:0060026 118 0.023
regulation of biosynthetic process GO:0009889 250 0.023
Fly
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.023
lateral inhibition GO:0046331 1 0.023
protein targeting to nucleus GO:0044744 3 0.023
regulation of phosphorus metabolic process GO:0051174 43 0.023
Mouse
negative regulation of jnk cascade GO:0046329 1 0.023
Mouse
regulation of circadian rhythm GO:0042752 4 0.023
anatomical structure homeostasis GO:0060249 36 0.022
Zebrafish Fly
female gonad development GO:0008585 4 0.022
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.022
photoreceptor cell morphogenesis GO:0008594 1 0.022
regulation of cellular ketone metabolic process GO:0010565 7 0.022
mitotic cell cycle checkpoint GO:0007093 5 0.022
Fly
negative regulation of cellular metabolic process GO:0031324 77 0.022
Mouse
positive regulation of nuclease activity GO:0032075 1 0.022
negative regulation of secretion by cell GO:1903531 2 0.022
positive regulation of multi organism process GO:0043902 3 0.022
protein demethylation GO:0006482 2 0.022
positive regulation of nucleoside metabolic process GO:0045979 1 0.022
heterocycle metabolic process GO:0046483 290 0.022
Mouse Worm
cell migration involved in gastrulation GO:0042074 79 0.021
generation of neurons GO:0048699 385 0.021
Human Mouse Rat Fly
oxoacid metabolic process GO:0043436 31 0.021
protein import into nucleus GO:0006606 3 0.021
regulation of tube size GO:0035150 2 0.021
dna biosynthetic process GO:0071897 3 0.021
establishment of mitotic spindle localization GO:0040001 12 0.021
Human Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.021
Fly
positive regulation of neuron apoptotic process GO:0043525 1 0.021
stem cell differentiation GO:0048863 117 0.021
Fly
regulation of cellular component organization GO:0051128 86 0.021
Rat Fly
single organism nuclear import GO:1902593 3 0.021
cellular response to biotic stimulus GO:0071216 3 0.021
positive regulation of wound healing GO:0090303 1 0.021
cellular response to external stimulus GO:0071496 2 0.021
catechol containing compound biosynthetic process GO:0009713 2 0.021
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.021
modification dependent protein catabolic process GO:0019941 3 0.021
negative regulation of macromolecule metabolic process GO:0010605 76 0.021
protein stabilization GO:0050821 2 0.020
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 1 0.020
development of primary female sexual characteristics GO:0046545 4 0.020
regulation of response to nutrient levels GO:0032107 1 0.020
negative regulation of nucleic acid templated transcription GO:1903507 45 0.020
cellular ketone metabolic process GO:0042180 11 0.020
fatty acid elongation unsaturated fatty acid GO:0019368 1 0.020
negative regulation of signaling GO:0023057 96 0.020
Mouse
purine ribonucleotide metabolic process GO:0009150 27 0.020
Mouse
regulation of cell differentiation GO:0045595 142 0.020
Rat Fly
heart process GO:0003015 71 0.020
synaptic target recognition GO:0008039 1 0.020
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.020
positive regulation of cellular catabolic process GO:0031331 3 0.020
response to hydrogen peroxide GO:0042542 3 0.020
positive regulation of secretion GO:0051047 1 0.020
cellular response to extracellular stimulus GO:0031668 2 0.019
guanosine containing compound catabolic process GO:1901069 2 0.019
Mouse
protein dephosphorylation GO:0006470 3 0.019
regulation of signal transduction by p53 class mediator GO:1901796 9 0.019
mrna polyadenylation GO:0006378 2 0.019
ganglioside metabolic process GO:0001573 3 0.019
protein complex assembly GO:0006461 30 0.019
Worm Fly
mitotic cell cycle process GO:1903047 48 0.019
Human Worm Fly
cellular homeostasis GO:0019725 26 0.019
Fly
cellular response to starvation GO:0009267 1 0.019
regulation of cytoplasmic transport GO:1903649 4 0.019
photoreceptor cell maintenance GO:0045494 11 0.019
Zebrafish
rna metabolic process GO:0016070 219 0.019
positive regulation of apoptotic signaling pathway GO:2001235 1 0.019
cell death GO:0008219 121 0.019
sensory perception of chemical stimulus GO:0007606 3 0.019
nucleotide biosynthetic process GO:0009165 21 0.019
cellular macromolecule biosynthetic process GO:0034645 224 0.018
Fly
cellular amide metabolic process GO:0043603 4 0.018
neuronal action potential GO:0019228 18 0.018
localization of cell GO:0051674 244 0.018
Human Mouse Rat Fly
negative regulation of synapse assembly GO:0051964 2 0.018
digestive system development GO:0055123 289 0.018
regulation of cell death GO:0010941 103 0.018
regulation of heart contraction GO:0008016 32 0.018
regulation of synapse assembly GO:0051963 3 0.018
regulation of cell cycle process GO:0010564 20 0.018
Fly
multi organism reproductive process GO:0044703 36 0.018
Mouse Worm Fly
positive regulation of epithelial cell proliferation GO:0050679 1 0.018
nuclear import GO:0051170 3 0.018
modulation by virus of host morphology or physiology GO:0019048 1 0.018
nucleus localization GO:0051647 8 0.018
Zebrafish Rat Worm Fly
gene expression GO:0010467 252 0.018
Fly
regulation of endocrine process GO:0044060 2 0.017
regulation of response to stress GO:0080134 36 0.017
Mouse
thermosensory behavior GO:0040040 1 0.017
spinal cord development GO:0021510 46 0.017
single organism intracellular transport GO:1902582 25 0.017
Mouse Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.017
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.017
negative regulation of neural precursor cell proliferation GO:2000178 1 0.017
apoptotic process GO:0006915 116 0.017

pafah1b1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
physical disorder DOID:0080015 0 0.249
Human
congenital nervous system abnormality DOID:2490 0 0.249
Human
lissencephaly DOID:0050453 0 0.247
Human
disease of anatomical entity DOID:7 0 0.115
central nervous system disease DOID:331 0 0.077
neurodegenerative disease DOID:1289 0 0.077
nervous system disease DOID:863 0 0.077
tauopathy DOID:680 0 0.047
disease of metabolism DOID:0014667 0 0.024
lipid storage disease DOID:9455 0 0.024
lysosomal storage disease DOID:3211 0 0.024
inherited metabolic disorder DOID:655 0 0.024
dementia DOID:1307 0 0.017
disease of mental health DOID:150 0 0.017
cognitive disorder DOID:1561 0 0.017