Danio rerio

0 known processes

plp1b

proteolipid protein 1b

(Aliases: wu:fv76c02,zgc:91786,DMalpha2a,DMalpha2b,DMalpha2c)

plp1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ development GO:0007423 393 0.695
central nervous system development GO:0007417 387 0.655
Human Mouse
transmission of nerve impulse GO:0019226 19 0.568
Zebrafish Mouse Rat
multicellular organismal signaling GO:0035637 22 0.451
Zebrafish Mouse Rat
head development GO:0060322 303 0.414
Human
hindbrain development GO:0030902 91 0.380
eye development GO:0001654 277 0.326
axon ensheathment GO:0008366 18 0.325
Zebrafish Mouse Rat
system process GO:0003008 185 0.307
Zebrafish Mouse Rat
brain development GO:0007420 293 0.302
Human
cell migration GO:0016477 237 0.263
cgmp biosynthetic process GO:0006182 7 0.245
regulation of multicellular organismal development GO:2000026 223 0.231
cation transmembrane transport GO:0098655 65 0.197
positive regulation of biological process GO:0048518 253 0.197
Mouse
lateral line system development GO:0048925 76 0.187
cation transport GO:0006812 81 0.183
action potential GO:0001508 19 0.181
Zebrafish Mouse Rat
positive regulation of guanylate cyclase activity GO:0031284 6 0.176
cell cell junction organization GO:0045216 10 0.175
cell motility GO:0048870 244 0.169
neuron development GO:0048666 262 0.165
Zebrafish Mouse
regulation of biological quality GO:0065008 263 0.164
Zebrafish Mouse Rat
regulation of lyase activity GO:0051339 12 0.141
glial cell development GO:0021782 20 0.137
Mouse
camera type eye development GO:0043010 222 0.135
positive regulation of cyclic nucleotide metabolic process GO:0030801 8 0.134
adult behavior GO:0030534 2 0.132
cell junction organization GO:0034330 11 0.121
tube morphogenesis GO:0035239 349 0.109
monovalent inorganic cation transport GO:0015672 42 0.108
monocarboxylic acid biosynthetic process GO:0072330 12 0.104
Mouse
nitrogen compound metabolic process GO:0006807 319 0.103
small molecule metabolic process GO:0044281 77 0.099
Mouse
ion transport GO:0006811 114 0.097
regulation of membrane potential GO:0042391 23 0.096
Zebrafish Mouse Rat
single organism metabolic process GO:0044710 217 0.094
Mouse
regulation of sodium ion transport GO:0002028 2 0.093
semicircular canal development GO:0060872 24 0.093
organic cyclic compound biosynthetic process GO:1901362 223 0.093
regulation of cyclic nucleotide biosynthetic process GO:0030802 15 0.093
divalent inorganic cation homeostasis GO:0072507 22 0.091
oxoacid metabolic process GO:0043436 31 0.089
Mouse
neurological system process GO:0050877 62 0.089
Zebrafish Mouse Rat
regulation of metal ion transport GO:0010959 4 0.087
cellular component movement GO:0006928 335 0.086
positive regulation of transport GO:0051050 2 0.086
regulation of developmental process GO:0050793 247 0.085
biological adhesion GO:0022610 40 0.084
regionalization GO:0003002 274 0.083
morphogenesis of an epithelium GO:0002009 333 0.083
neuron projection morphogenesis GO:0048812 161 0.082
cell morphogenesis GO:0000902 289 0.082
extracellular structure organization GO:0043062 27 0.078
organic cyclic compound metabolic process GO:1901360 301 0.076
neuron projection development GO:0031175 180 0.075
Zebrafish Mouse
nerve development GO:0021675 45 0.075
fatty acid biosynthetic process GO:0006633 4 0.074
Mouse
long chain fatty acid metabolic process GO:0001676 1 0.070
Mouse
larval development GO:0002164 2 0.070
transmembrane transport GO:0055085 120 0.070
biosynthetic process GO:0009058 294 0.069
Mouse
blood vessel morphogenesis GO:0048514 216 0.069
neuron differentiation GO:0030182 353 0.069
Zebrafish Mouse
negative regulation of multicellular organismal process GO:0051241 69 0.069
establishment of epithelial cell polarity GO:0090162 2 0.068
cellular nitrogen compound biosynthetic process GO:0044271 218 0.066
positive regulation of nucleotide biosynthetic process GO:0030810 8 0.064
cellular nitrogen compound metabolic process GO:0034641 290 0.064
response to chemical GO:0042221 320 0.062
organic substance biosynthetic process GO:1901576 289 0.062
Mouse
glucose import GO:0046323 2 0.062
regulation of macromolecule biosynthetic process GO:0010556 225 0.061
axon development GO:0061564 166 0.060
Mouse
developmental growth involved in morphogenesis GO:0060560 86 0.060
cognition GO:0050890 1 0.060
neuronal action potential GO:0019228 18 0.059
Zebrafish Mouse Rat
regulation of filopodium assembly GO:0051489 2 0.058
Zebrafish
gas transport GO:0015669 3 0.058
neurotransmitter transport GO:0006836 2 0.058
regulation of ion transport GO:0043269 22 0.055
organonitrogen compound metabolic process GO:1901564 74 0.055
organophosphate metabolic process GO:0019637 37 0.054
ensheathment of neurons GO:0007272 18 0.053
Zebrafish Mouse Rat
sleep GO:0030431 1 0.053
epithelial tube morphogenesis GO:0060562 148 0.053
maintenance of location GO:0051235 4 0.051
aromatic compound biosynthetic process GO:0019438 217 0.051
generation of neurons GO:0048699 385 0.051
Zebrafish Mouse
positive regulation of lyase activity GO:0051349 6 0.051
heterocycle biosynthetic process GO:0018130 215 0.050
single organism biosynthetic process GO:0044711 71 0.049
Mouse
neural nucleus development GO:0048857 15 0.049
Human
localization of cell GO:0051674 244 0.049
stem cell differentiation GO:0048863 117 0.048
inorganic cation transmembrane transport GO:0098662 50 0.048
lateral line development GO:0048882 66 0.047
cellular ion homeostasis GO:0006873 17 0.047
lens fiber cell development GO:0070307 3 0.047
positive regulation of developmental process GO:0051094 50 0.046
regulation of cellular component organization GO:0051128 86 0.046
Zebrafish
muscle structure development GO:0061061 196 0.045
cgmp metabolic process GO:0046068 7 0.045
amine metabolic process GO:0009308 2 0.044
transport GO:0006810 220 0.044
regulation of cell projection assembly GO:0060491 4 0.044
Zebrafish
regulation of cell differentiation GO:0045595 142 0.043
aging GO:0007568 2 0.043
positive regulation of cgmp biosynthetic process GO:0030828 6 0.042
regulation of neurogenesis GO:0050767 87 0.042
cellular component biogenesis GO:0044085 178 0.042
Zebrafish
immune system development GO:0002520 191 0.042
single organism transport GO:0044765 206 0.041
neuromast development GO:0048884 46 0.041
establishment of endothelial barrier GO:0061028 3 0.041
cellular component assembly GO:0022607 170 0.040
Zebrafish
sodium ion transport GO:0006814 24 0.040
central nervous system myelination GO:0022010 2 0.040
Mouse
neuron neuron synaptic transmission GO:0007270 1 0.039
cell part morphogenesis GO:0032990 246 0.039
regulation of nucleotide biosynthetic process GO:0030808 15 0.039
regulation of glucose import GO:0046324 1 0.039
regulation of muscle contraction GO:0006937 3 0.038
cell adhesion GO:0007155 40 0.038
single organism localization GO:1902578 225 0.038
exocytosis GO:0006887 1 0.038
regulation of cgmp metabolic process GO:0030823 6 0.037
nucleobase containing compound metabolic process GO:0006139 274 0.037
polarized epithelial cell differentiation GO:0030859 4 0.037
establishment of localization GO:0051234 244 0.036
epithelial cell development GO:0002064 42 0.036
apical junction assembly GO:0043297 1 0.036
positive regulation of multicellular organismal process GO:0051240 52 0.035
regulation of glucose transport GO:0010827 1 0.035
nucleoside monophosphate catabolic process GO:0009125 4 0.035
cellular component maintenance GO:0043954 3 0.034
growth GO:0040007 174 0.034
cell cell junction maintenance GO:0045217 1 0.034
sodium ion transmembrane transport GO:0035725 21 0.034
sensory system development GO:0048880 76 0.033
heart morphogenesis GO:0003007 156 0.033
startle response GO:0001964 4 0.033
central nervous system neuron differentiation GO:0021953 74 0.033
embryonic organ morphogenesis GO:0048562 274 0.033
cell projection organization GO:0030030 284 0.032
Zebrafish Mouse
cellular amine metabolic process GO:0044106 2 0.032
lipid storage GO:0019915 1 0.032
response to external stimulus GO:0009605 264 0.032
cell projection morphogenesis GO:0048858 244 0.031
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.031
regulation of cellular amine metabolic process GO:0033238 0 0.030
inorganic ion transmembrane transport GO:0098660 57 0.030
response to steroid hormone GO:0048545 35 0.030
embryonic organ development GO:0048568 381 0.030
single organism behavior GO:0044708 24 0.030
regulation of nitrogen compound metabolic process GO:0051171 251 0.029
ion transmembrane transport GO:0034220 91 0.029
regulation of cellular amino acid metabolic process GO:0006521 0 0.029
regulation of primary metabolic process GO:0080090 311 0.029
ribonucleotide metabolic process GO:0009259 27 0.029
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.029
metal ion homeostasis GO:0055065 26 0.028
cell substrate adhesion GO:0031589 4 0.028
long chain fatty acid biosynthetic process GO:0042759 1 0.028
Mouse
regulation of cgmp biosynthetic process GO:0030826 6 0.028
ion homeostasis GO:0050801 41 0.027
posterior lateral line nerve development GO:0048918 8 0.027
regulation of macromolecule metabolic process GO:0060255 317 0.027
Mouse
regulation of transport GO:0051049 45 0.026
response to hormone GO:0009725 48 0.026
adherens junction organization GO:0034332 4 0.026
ribonucleoside monophosphate catabolic process GO:0009158 4 0.026
regulation of cytoplasmic transport GO:1903649 4 0.025
endothelial cell differentiation GO:0045446 20 0.025
regulation of cell projection organization GO:0031344 44 0.025
Zebrafish
regeneration GO:0031099 91 0.025
axon ensheathment in central nervous system GO:0032291 2 0.025
Mouse
glial cell differentiation GO:0010001 42 0.025
Mouse Rat
regulation of blood pressure GO:0008217 1 0.025
establishment of epithelial cell apical basal polarity GO:0045198 2 0.024
hormone transport GO:0009914 2 0.024
positive regulation of blood circulation GO:1903524 2 0.024
muscle organ development GO:0007517 101 0.024
cell matrix adhesion GO:0007160 4 0.024
positive regulation of cell cycle GO:0045787 3 0.024
cellular biosynthetic process GO:0044249 286 0.024
Mouse
calcium ion homeostasis GO:0055074 19 0.024
midbrain development GO:0030901 28 0.023
Human
rna biosynthetic process GO:0032774 181 0.023
cellular ketone metabolic process GO:0042180 11 0.023
regulation of metabolic process GO:0019222 359 0.023
Mouse
positive regulation of secretion GO:0051047 1 0.023
gene expression GO:0010467 252 0.023
Mouse
response to wounding GO:0009611 116 0.023
organic acid metabolic process GO:0006082 31 0.022
Mouse
carboxylic acid biosynthetic process GO:0046394 12 0.022
Mouse
metal ion transport GO:0030001 58 0.022
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 8 0.022
carboxylic acid metabolic process GO:0019752 22 0.021
Mouse
stem cell fate commitment GO:0048865 1 0.021
regulation of cell shape GO:0008360 1 0.021
membrane repolarization GO:0086009 2 0.021
regulation of neuronal synaptic plasticity GO:0048168 1 0.021
purine nucleoside monophosphate catabolic process GO:0009128 4 0.021
axonogenesis GO:0007409 152 0.021
locomotory behavior GO:0007626 34 0.021
heart development GO:0007507 313 0.021
extracellular matrix assembly GO:0085029 1 0.020
regulation of glial cell differentiation GO:0045685 4 0.020
regulation of oligodendrocyte differentiation GO:0048713 1 0.020
negative regulation of developmental process GO:0051093 65 0.020
regulation of cellular ketone metabolic process GO:0010565 7 0.020
sensory organ morphogenesis GO:0090596 200 0.020
regulation of ion transmembrane transporter activity GO:0032412 2 0.020
regulation of signaling GO:0023051 235 0.020
positive regulation of cell adhesion GO:0045785 1 0.020
cellular amino acid metabolic process GO:0006520 7 0.020
positive regulation of metabolic process GO:0009893 108 0.020
Mouse
regulation of circadian rhythm GO:0042752 4 0.020
regulation of multicellular organismal process GO:0051239 277 0.020
purine containing compound metabolic process GO:0072521 29 0.020
determination of heart left right asymmetry GO:0061371 117 0.019
neural tube development GO:0021915 62 0.019
ribose phosphate biosynthetic process GO:0046390 20 0.019
digestive system development GO:0055123 289 0.019
negative regulation of cellular process GO:0048523 283 0.019
positive regulation of cgmp metabolic process GO:0030825 6 0.019
regulation of anatomical structure morphogenesis GO:0022603 130 0.019
positive regulation of immune effector process GO:0002699 3 0.019
nuclear transport GO:0051169 4 0.019
neurotransmitter secretion GO:0007269 2 0.018
regulation of cell substrate adhesion GO:0010810 1 0.018
cell growth GO:0016049 57 0.018
circulatory system process GO:0003013 87 0.018
sequestering of metal ion GO:0051238 3 0.018
establishment of apical basal cell polarity GO:0035089 2 0.017
neuron migration GO:0001764 22 0.017
synaptic vesicle transport GO:0048489 1 0.017
regulation of erk1 and erk2 cascade GO:0070372 4 0.017
monoamine transport GO:0015844 1 0.017
actin filament based movement GO:0030048 1 0.017
phosphatidylinositol mediated signaling GO:0048015 2 0.017
regulation of cell adhesion GO:0030155 15 0.017
cell junction maintenance GO:0034331 2 0.017
nucleotide metabolic process GO:0009117 28 0.017
cellular aromatic compound metabolic process GO:0006725 295 0.017
regulation of cell matrix adhesion GO:0001952 1 0.017
chordate embryonic development GO:0043009 271 0.017
regulation of establishment of protein localization GO:0070201 4 0.017
regulation of mrna processing GO:0050684 3 0.017
inositol lipid mediated signaling GO:0048017 2 0.017
locomotion GO:0040011 313 0.017
atp catabolic process GO:0006200 4 0.017
positive regulation of cyclase activity GO:0031281 6 0.016
establishment of monopolar cell polarity GO:0061162 2 0.016
negative regulation of signaling GO:0023057 96 0.016
synaptic transmission GO:0007268 35 0.016
semicircular canal morphogenesis GO:0048752 18 0.016
organic acid biosynthetic process GO:0016053 12 0.016
Mouse
cell cell signaling GO:0007267 52 0.016
skeletal muscle organ development GO:0060538 78 0.016
membrane hyperpolarization GO:0060081 1 0.016
astrocyte differentiation GO:0048708 1 0.016
Mouse
nuclear export GO:0051168 1 0.016
regulation of cell size GO:0008361 29 0.016
muscle cell development GO:0055001 115 0.016
regulation of wound healing GO:0061041 2 0.016
myelination of lateral line nerve axons GO:0048897 5 0.016
regulation of cellular component size GO:0032535 30 0.016
neuroblast proliferation GO:0007405 2 0.015
receptor internalization GO:0031623 2 0.015
embryonic cranial skeleton morphogenesis GO:0048701 90 0.015
carbohydrate derivative biosynthetic process GO:1901137 43 0.015
skeletal system development GO:0001501 181 0.015
establishment of blood brain barrier GO:0060856 2 0.015
regulation of neurological system process GO:0031644 2 0.015
regulation of rna metabolic process GO:0051252 224 0.015
cranial nerve development GO:0021545 42 0.015
neuron recognition GO:0008038 18 0.015
regulation of extent of cell growth GO:0061387 29 0.015
regulation of nervous system development GO:0051960 90 0.015
regulation of cellular metabolic process GO:0031323 320 0.015
single organismal cell cell adhesion GO:0016337 29 0.015
chemosensory behavior GO:0007635 1 0.015
regulation of cell activation GO:0050865 1 0.015
gliogenesis GO:0042063 45 0.014
Mouse Rat
cytokinesis GO:0000910 3 0.014
regulation of cellular biosynthetic process GO:0031326 245 0.014
neuroblast differentiation GO:0014016 1 0.014
regulation of cell morphogenesis GO:0022604 42 0.014
cellular response to stress GO:0033554 62 0.014
angiogenesis GO:0001525 158 0.014
response to drug GO:0042493 3 0.014
embryonic hemopoiesis GO:0035162 53 0.014
carbohydrate derivative metabolic process GO:1901135 61 0.014
mesenchymal cell development GO:0014031 78 0.014
peptidyl serine modification GO:0018209 2 0.014
catecholamine biosynthetic process GO:0042423 2 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
spinal cord motor neuron differentiation GO:0021522 26 0.014
rna metabolic process GO:0016070 219 0.014
sensory perception GO:0007600 39 0.014
catechol containing compound biosynthetic process GO:0009713 2 0.014
regulation of blood vessel size GO:0050880 2 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
peripheral nervous system development GO:0007422 55 0.014
oligodendrocyte development GO:0014003 7 0.014
Mouse
response to organic substance GO:0010033 153 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
mesenchyme development GO:0060485 127 0.013
regulation of biosynthetic process GO:0009889 250 0.013
vasculature development GO:0001944 278 0.013
response to endogenous stimulus GO:0009719 83 0.013
nitrogen compound transport GO:0071705 23 0.013
regulation of circadian sleep wake cycle sleep GO:0045187 1 0.013
multicellular organism growth GO:0035264 4 0.013
neuroblast fate commitment GO:0014017 1 0.013
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.013
cellular component morphogenesis GO:0032989 336 0.013
collagen fibril organization GO:0030199 1 0.013
heterocycle metabolic process GO:0046483 290 0.013
neuron projection regeneration GO:0031102 16 0.013
ear development GO:0043583 127 0.013
indole containing compound metabolic process GO:0042430 2 0.013
taxis GO:0042330 109 0.013
hemopoiesis GO:0030097 183 0.013
macromolecular complex disassembly GO:0032984 1 0.013
cellular response to decreased oxygen levels GO:0036294 1 0.012
neuron projection guidance GO:0097485 86 0.012
regulation of response to stimulus GO:0048583 269 0.012
positive regulation of gene expression GO:0010628 71 0.012
Mouse
regulation of calcium ion transport GO:0051924 2 0.012
regulation of cyclase activity GO:0031279 12 0.012
positive regulation of wound healing GO:0090303 1 0.012
regulation of tube size GO:0035150 2 0.012
blood vessel development GO:0001568 246 0.012
cellular respiration GO:0045333 3 0.012
cellular divalent inorganic cation homeostasis GO:0072503 13 0.012
developmental cell growth GO:0048588 52 0.012
positive regulation of secretion by cell GO:1903532 1 0.012
lens development in camera type eye GO:0002088 22 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
cortical cytoskeleton organization GO:0030865 1 0.012
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.012
axon extension GO:0048675 45 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 15 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.012
cell migration involved in heart development GO:0060973 22 0.012
cellular response to oxygen levels GO:0071453 1 0.012
response to stress GO:0006950 263 0.012
Mouse
response to vitamin GO:0033273 3 0.012
cellular response to chemical stimulus GO:0070887 157 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 15 0.012
post embryonic organ development GO:0048569 4 0.012
nucleocytoplasmic transport GO:0006913 4 0.011
positive regulation of glucose import GO:0046326 1 0.011
positive regulation of neurogenesis GO:0050769 24 0.011
cellular response to hypoxia GO:0071456 1 0.011
cellular amino acid biosynthetic process GO:0008652 2 0.011
mitochondrion organization GO:0007005 4 0.011
alpha amino acid metabolic process GO:1901605 3 0.011
regulation of cellular component movement GO:0051270 55 0.011
synaptic growth at neuromuscular junction GO:0051124 2 0.011
carbon dioxide transport GO:0015670 3 0.011
ear morphogenesis GO:0042471 64 0.011
regulation of receptor internalization GO:0002090 2 0.011
sequestering of calcium ion GO:0051208 3 0.011
fertilization GO:0009566 3 0.011
regulation of axonogenesis GO:0050770 32 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
heart looping GO:0001947 94 0.011
gastrulation GO:0007369 208 0.011
posterior lateral line nerve glial cell development GO:0048941 5 0.011
establishment of protein localization to organelle GO:0072594 4 0.011
muscle cell differentiation GO:0042692 139 0.011
regulation of protein transport GO:0051223 3 0.011
negative regulation of heart contraction GO:0045822 2 0.011
behavior GO:0007610 74 0.011
regulation of gene expression GO:0010468 265 0.011
Mouse
regulation of localization GO:0032879 104 0.011
somite development GO:0061053 96 0.011
positive regulation of cell development GO:0010720 25 0.010
regulation of neurotransmitter transport GO:0051588 1 0.010
ventral spinal cord development GO:0021517 35 0.010
regulation of cell development GO:0060284 100 0.010
metencephalon development GO:0022037 27 0.010
regulation of reproductive process GO:2000241 4 0.010
response to amine GO:0014075 1 0.010
response to monosaccharide GO:0034284 3 0.010
peptidyl serine phosphorylation GO:0018105 1 0.010
circadian sleep wake cycle sleep GO:0050802 1 0.010
lipid metabolic process GO:0006629 52 0.010
Mouse
regulation of cardiac muscle cell contraction GO:0086004 1 0.010
positive regulation of map kinase activity GO:0043406 3 0.010

plp1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
Human
nervous system disease DOID:863 0 0.011
Human