Danio rerio

0 known processes

sc:d0319

sc:d0319

(Aliases: slitrk2)

sc:d0319 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cognition GO:0050890 1 0.569
stem cell proliferation GO:0072089 4 0.333
regulation of circadian rhythm GO:0042752 4 0.266
regulation of biological quality GO:0065008 263 0.263
regulation of multicellular organism growth GO:0040014 4 0.190
regulation of multicellular organismal process GO:0051239 277 0.171
regulation of synaptic plasticity GO:0048167 1 0.161
peptidyl serine phosphorylation GO:0018105 1 0.152
tube morphogenesis GO:0035239 349 0.147
synaptic transmission GO:0007268 35 0.144
central nervous system development GO:0007417 387 0.141
response to organic substance GO:0010033 153 0.137
response to chemical GO:0042221 320 0.135
head development GO:0060322 303 0.119
peptidyl serine modification GO:0018209 2 0.106
signal transduction GO:0007165 455 0.102
eye development GO:0001654 277 0.096
larval development GO:0002164 2 0.094
developmental growth GO:0048589 166 0.090
neuron development GO:0048666 262 0.085
sensory organ development GO:0007423 393 0.083
embryonic organ development GO:0048568 381 0.082
nucleic acid metabolic process GO:0090304 244 0.081
neuroblast proliferation GO:0007405 2 0.080
negative regulation of programmed cell death GO:0043069 58 0.076
single organism localization GO:1902578 225 0.075
growth GO:0040007 174 0.074
regulation of apoptotic process GO:0042981 98 0.071
cell projection morphogenesis GO:0048858 244 0.070
glutamate receptor signaling pathway GO:0007215 1 0.068
eye morphogenesis GO:0048592 144 0.068
cell morphogenesis involved in differentiation GO:0000904 195 0.065
protein modification process GO:0036211 100 0.064
cell surface receptor signaling pathway GO:0007166 325 0.063
neurotransmitter transport GO:0006836 2 0.063
response to abiotic stimulus GO:0009628 122 0.063
multicellular organism growth GO:0035264 4 0.061
cellular response to organic substance GO:0071310 105 0.061
cellular component morphogenesis GO:0032989 336 0.060
regulation of developmental process GO:0050793 247 0.059
positive regulation of transport GO:0051050 2 0.057
nitrogen compound metabolic process GO:0006807 319 0.055
cellular component assembly GO:0022607 170 0.054
regulation of cell death GO:0010941 103 0.054
aging GO:0007568 2 0.053
cell proliferation GO:0008283 80 0.052
small molecule metabolic process GO:0044281 77 0.052
regulation of neuronal synaptic plasticity GO:0048168 1 0.052
regulation of synapse organization GO:0050807 3 0.051
response to ketone GO:1901654 1 0.051
brain development GO:0007420 293 0.050
morphogenesis of an epithelium GO:0002009 333 0.050
guanosine containing compound metabolic process GO:1901068 4 0.049
regulation of signaling GO:0023051 235 0.048
directional locomotion GO:0033058 1 0.047
response to external stimulus GO:0009605 264 0.047
organonitrogen compound metabolic process GO:1901564 74 0.047
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.047
cell migration GO:0016477 237 0.047
death GO:0016265 121 0.046
adult behavior GO:0030534 2 0.046
organic cyclic compound metabolic process GO:1901360 301 0.045
single organism cellular localization GO:1902580 46 0.045
cell projection organization GO:0030030 284 0.043
cell death GO:0008219 121 0.043
meiotic nuclear division GO:0007126 4 0.043
developmental cell growth GO:0048588 52 0.042
blood vessel morphogenesis GO:0048514 216 0.041
cellular aromatic compound metabolic process GO:0006725 295 0.041
localization of cell GO:0051674 244 0.041
generation of neurons GO:0048699 385 0.041
regulation of multicellular organismal development GO:2000026 223 0.041
regulation of cell shape GO:0008360 1 0.040
gtp metabolic process GO:0046039 4 0.040
regulation of establishment of protein localization GO:0070201 4 0.040
cell cell signaling GO:0007267 52 0.039
cellular nitrogen compound metabolic process GO:0034641 290 0.039
rhythmic process GO:0048511 21 0.039
axon development GO:0061564 166 0.038
negative regulation of protein phosphorylation GO:0001933 4 0.038
heart development GO:0007507 313 0.037
guanosine containing compound catabolic process GO:1901069 2 0.037
single organism transport GO:0044765 206 0.037
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.037
regulation of gene expression GO:0010468 265 0.037
cellular response to xenobiotic stimulus GO:0071466 35 0.037
cell part morphogenesis GO:0032990 246 0.037
regulation of nucleoside metabolic process GO:0009118 2 0.036
camera type eye development GO:0043010 222 0.036
regulation of cellular amine metabolic process GO:0033238 0 0.035
negative regulation of apoptotic process GO:0043066 55 0.035
cellular response to chemical stimulus GO:0070887 157 0.035
system process GO:0003008 185 0.035
cellular macromolecule metabolic process GO:0044260 391 0.034
circadian regulation of gene expression GO:0032922 8 0.034
vasculature development GO:0001944 278 0.034
antimicrobial humoral response GO:0019730 2 0.033
developmental growth involved in morphogenesis GO:0060560 86 0.032
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 1 0.032
response to monosaccharide GO:0034284 3 0.032
regulation of endocrine process GO:0044060 2 0.032
transport GO:0006810 220 0.031
gene expression GO:0010467 252 0.030
regulation of intracellular protein transport GO:0033157 3 0.030
protein localization to membrane GO:0072657 9 0.030
developmental programmed cell death GO:0010623 4 0.030
sleep GO:0030431 1 0.030
epithelial tube morphogenesis GO:0060562 148 0.030
reproductive process GO:0022414 40 0.029
regulation of cell communication GO:0010646 232 0.029
determination of heart left right asymmetry GO:0061371 117 0.029
embryo development ending in birth or egg hatching GO:0009792 271 0.029
cell cell junction maintenance GO:0045217 1 0.029
mitochondrion organization GO:0007005 4 0.028
ameboidal type cell migration GO:0001667 143 0.027
response to stress GO:0006950 263 0.027
regulation of protein transport GO:0051223 3 0.027
positive regulation of translation GO:0045727 1 0.027
cellular localization GO:0051641 97 0.027
cellular component maintenance GO:0043954 3 0.027
regulation of cytoplasmic transport GO:1903649 4 0.027
positive regulation of cellular component biogenesis GO:0044089 3 0.026
regulation of programmed cell death GO:0043067 101 0.026
establishment of localization GO:0051234 244 0.026
programmed cell death GO:0012501 119 0.026
regulation of purine nucleotide catabolic process GO:0033121 2 0.026
regulation of cellular biosynthetic process GO:0031326 245 0.026
positive regulation of macromolecule metabolic process GO:0010604 93 0.026
gtp catabolic process GO:0006184 2 0.026
neuron projection morphogenesis GO:0048812 161 0.026
establishment of localization in cell GO:0051649 77 0.026
membrane hyperpolarization GO:0060081 1 0.026
membrane fusion GO:0061025 2 0.026
regulation of neuron differentiation GO:0045664 56 0.025
cellular protein modification process GO:0006464 100 0.025
cellular ketone metabolic process GO:0042180 11 0.024
maintenance of location GO:0051235 4 0.024
spermatid development GO:0007286 2 0.024
regulation of gtp catabolic process GO:0033124 2 0.024
female gonad development GO:0008585 4 0.024
cell motility GO:0048870 244 0.024
neural precursor cell proliferation GO:0061351 20 0.024
blood vessel development GO:0001568 246 0.023
cellular response to external stimulus GO:0071496 2 0.023
mitochondrial transport GO:0006839 2 0.023
cell growth GO:0016049 57 0.023
autophagy GO:0006914 4 0.023
regulation of developmental growth GO:0048638 38 0.023
regulation of nucleotide catabolic process GO:0030811 2 0.023
phagocytosis GO:0006909 3 0.023
cellular protein metabolic process GO:0044267 129 0.023
amine metabolic process GO:0009308 2 0.023
regulation of cellular component organization GO:0051128 86 0.023
negative regulation of cell communication GO:0010648 96 0.022
cellular nitrogen compound biosynthetic process GO:0044271 218 0.022
cell junction maintenance GO:0034331 2 0.022
transcription dna templated GO:0006351 181 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
response to lipid GO:0033993 60 0.022
hematopoietic or lymphoid organ development GO:0048534 191 0.022
cellular amine metabolic process GO:0044106 2 0.022
negative regulation of cell death GO:0060548 60 0.022
hormone secretion GO:0046879 2 0.022
regulation of macromolecule biosynthetic process GO:0010556 225 0.022
regulation of macromolecule metabolic process GO:0060255 317 0.022
establishment of synaptic vesicle localization GO:0097480 1 0.022
cellular response to extracellular stimulus GO:0031668 2 0.022
positive regulation of secretion GO:0051047 1 0.021
locomotor rhythm GO:0045475 3 0.021
regulation of binding GO:0051098 3 0.021
taxis GO:0042330 109 0.021
regulation of cell activation GO:0050865 1 0.021
regulation of reproductive process GO:2000241 4 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
regulation of transmembrane transporter activity GO:0022898 2 0.021
cellular response to starvation GO:0009267 1 0.021
single organism organelle organization GO:1902589 199 0.021
response to inorganic substance GO:0010035 38 0.021
camera type eye morphogenesis GO:0048593 108 0.020
cell morphogenesis GO:0000902 289 0.020
heterocycle metabolic process GO:0046483 290 0.020
regulation of neurotransmitter transport GO:0051588 1 0.020
regulation of gtpase activity GO:0043087 2 0.020
smooth muscle contraction GO:0006939 2 0.020
ovulation cycle GO:0042698 2 0.020
phosphorus metabolic process GO:0006793 109 0.020
female sex differentiation GO:0046660 4 0.020
response to hormone GO:0009725 48 0.020
stem cell maintenance GO:0019827 4 0.020
steroid hormone secretion GO:0035929 1 0.020
embryonic organ morphogenesis GO:0048562 274 0.019
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.019
exocytosis GO:0006887 1 0.019
protein localization GO:0008104 40 0.019
positive regulation of secretion by cell GO:1903532 1 0.019
protein metabolic process GO:0019538 183 0.019
cellular component movement GO:0006928 335 0.019
response to corticosteroid GO:0031960 1 0.019
regulation of metabolic process GO:0019222 359 0.019
response to hexose GO:0009746 3 0.019
response to carbohydrate GO:0009743 3 0.019
digestive system development GO:0055123 289 0.019
positive regulation of lipase activity GO:0060193 1 0.019
negative regulation of signal transduction GO:0009968 94 0.019
digestive tract mesoderm development GO:0007502 1 0.019
positive regulation of catabolic process GO:0009896 4 0.018
neuron projection extension GO:1990138 45 0.018
regulation of cellular component size GO:0032535 30 0.018
macromolecule modification GO:0043412 111 0.018
catabolic process GO:0009056 32 0.018
nucleobase containing compound metabolic process GO:0006139 274 0.018
phosphorylation GO:0016310 69 0.018
morphogenesis of an epithelial sheet GO:0002011 49 0.018
neuron projection development GO:0031175 180 0.018
protein secretion GO:0009306 1 0.018
nucleocytoplasmic transport GO:0006913 4 0.018
positive regulation of biological process GO:0048518 253 0.018
regulation of receptor activity GO:0010469 2 0.018
compound eye development GO:0048749 2 0.017
regulation of nitrogen compound metabolic process GO:0051171 251 0.017
neurotransmitter secretion GO:0007269 2 0.017
protein phosphorylation GO:0006468 47 0.017
regulation of retina development in camera type eye GO:1902866 2 0.017
negative regulation of metabolic process GO:0009892 86 0.017
single organism metabolic process GO:0044710 217 0.017
regulation of molecular function GO:0065009 70 0.017
regulation of localization GO:0032879 104 0.017
negative regulation of synapse assembly GO:0051964 2 0.017
tissue remodeling GO:0048771 4 0.017
regulation of extent of cell growth GO:0061387 29 0.017
positive regulation of cell cycle GO:0045787 3 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
establishment of protein localization to organelle GO:0072594 4 0.016
nuclear transport GO:0051169 4 0.016
response to glucocorticoid GO:0051384 1 0.016
regulation of rho protein signal transduction GO:0035023 2 0.016
vesicle localization GO:0051648 27 0.016
regulation of phospholipase activity GO:0010517 2 0.016
cellular component disassembly GO:0022411 1 0.016
neurological system process GO:0050877 62 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.016
regulation of ras gtpase activity GO:0032318 2 0.016
hemopoiesis GO:0030097 183 0.016
ovulation cycle process GO:0022602 2 0.015
cellular component biogenesis GO:0044085 178 0.015
sensory perception GO:0007600 39 0.015
regulation of cell projection organization GO:0031344 44 0.015
regulation of rna metabolic process GO:0051252 224 0.015
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 11 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of growth GO:0040008 42 0.015
regulation of cellular ketone metabolic process GO:0010565 7 0.015
phosphate containing compound metabolic process GO:0006796 108 0.015
regionalization GO:0003002 274 0.015
positive regulation of developmental process GO:0051094 50 0.015
response to xenobiotic stimulus GO:0009410 45 0.015
limbic system development GO:0021761 16 0.015
synaptic growth at neuromuscular junction GO:0051124 2 0.015
rna localization GO:0006403 4 0.015
cellular protein localization GO:0034613 20 0.015
epithelial cell differentiation GO:0030855 116 0.014
organelle organization GO:0006996 227 0.014
development of primary female sexual characteristics GO:0046545 4 0.014
muscle tissue development GO:0060537 110 0.014
organic acid metabolic process GO:0006082 31 0.014
behavior GO:0007610 74 0.014
cytoskeleton organization GO:0007010 96 0.014
response to endogenous stimulus GO:0009719 83 0.014
cellular macromolecule biosynthetic process GO:0034645 224 0.014
single organism membrane organization GO:0044802 20 0.014
neuron differentiation GO:0030182 353 0.014
synaptic vesicle transport GO:0048489 1 0.014
single organism intracellular transport GO:1902582 25 0.014
multi organism cellular process GO:0044764 2 0.014
intracellular transport GO:0046907 32 0.014
regulation of synapse assembly GO:0051963 3 0.014
rna metabolic process GO:0016070 219 0.014
protein import into nucleus GO:0006606 3 0.014
nephron morphogenesis GO:0072028 2 0.013
cell matrix adhesion GO:0007160 4 0.013
neural tube development GO:0021915 62 0.013
regulation of purine nucleotide metabolic process GO:1900542 17 0.013
regulation of protein modification process GO:0031399 29 0.013
carbohydrate derivative metabolic process GO:1901135 61 0.013
establishment of vesicle localization GO:0051650 24 0.013
regulation of nucleocytoplasmic transport GO:0046822 2 0.013
cell junction organization GO:0034330 11 0.013
osteoclast differentiation GO:0030316 1 0.013
negative regulation of cellular process GO:0048523 283 0.013
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 1 0.013
peptide transport GO:0015833 1 0.013
embryonic skeletal joint morphogenesis GO:0060272 3 0.013
negative regulation of gene expression GO:0010629 65 0.013
neuron neuron synaptic transmission GO:0007270 1 0.013
regulation of rna biosynthetic process GO:2001141 213 0.013
response to organic cyclic compound GO:0014070 51 0.013
positive regulation of protein complex assembly GO:0031334 2 0.013
adherens junction organization GO:0034332 4 0.013
establishment of organelle localization GO:0051656 45 0.013
response to other organism GO:0051707 97 0.013
hormone transport GO:0009914 2 0.013
apical junction assembly GO:0043297 1 0.013
regulation of signal transduction GO:0009966 225 0.013
regulation of cytokine production GO:0001817 3 0.012
response to alkaloid GO:0043279 2 0.012
lamellipodium organization GO:0097581 1 0.012
single organism behavior GO:0044708 24 0.012
regulation of cell size GO:0008361 29 0.012
positive regulation of gtpase activity GO:0043547 1 0.012
positive regulation of cell adhesion GO:0045785 1 0.012
apoptotic process GO:0006915 116 0.012
regulation of cell growth GO:0001558 29 0.012
regulation of meiotic cell cycle GO:0051445 1 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.012
embryonic skeletal joint development GO:0072498 3 0.012
positive regulation of molecular function GO:0044093 33 0.012
cellular response to endogenous stimulus GO:0071495 68 0.012
regulation of neuron projection development GO:0010975 40 0.012
positive regulation of erk1 and erk2 cascade GO:0070374 2 0.012
digestive tract morphogenesis GO:0048546 231 0.012
axonogenesis GO:0007409 152 0.012
multi organism process GO:0051704 134 0.012
brain morphogenesis GO:0048854 18 0.012
regulation of jak stat cascade GO:0046425 3 0.012
specification of symmetry GO:0009799 204 0.012
regulation of protein ubiquitination GO:0031396 3 0.012
locomotion GO:0040011 313 0.012
nuclear import GO:0051170 3 0.012
homeostatic process GO:0042592 142 0.012
response to drug GO:0042493 3 0.011
regulation of phosphate metabolic process GO:0019220 43 0.011
cellular catabolic process GO:0044248 27 0.011
organelle assembly GO:0070925 110 0.011
epiboly GO:0090504 41 0.011
synaptic vesicle localization GO:0097479 1 0.011
lipid storage GO:0019915 1 0.011
negative regulation of cellular metabolic process GO:0031324 77 0.011
activation of mapk activity GO:0000187 3 0.011
negative regulation of protein kinase activity GO:0006469 4 0.011
response to oxygen containing compound GO:1901700 55 0.011
production of molecular mediator of immune response GO:0002440 2 0.011
developmental maturation GO:0021700 34 0.011
regulation of collateral sprouting in absence of injury GO:0048696 4 0.011
positive regulation of synapse assembly GO:0051965 1 0.011
cellular response to vascular endothelial growth factor stimulus GO:0035924 3 0.011
angiogenesis GO:0001525 158 0.011
meiotic cell cycle process GO:1903046 3 0.011
cellular response to nutrient levels GO:0031669 2 0.011
organism emergence from protective structure GO:0071684 4 0.011
negative regulation of rna biosynthetic process GO:1902679 45 0.011
regulation of primary metabolic process GO:0080090 311 0.011
immune system process GO:0002376 241 0.011
organic cyclic compound biosynthetic process GO:1901362 223 0.011
centrosome localization GO:0051642 1 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 1 0.011
gland development GO:0048732 143 0.011
response to dexamethasone GO:0071548 1 0.011
sensory perception of chemical stimulus GO:0007606 3 0.011
regulation of oxidative stress induced cell death GO:1903201 2 0.011
positive regulation of nucleoside metabolic process GO:0045979 1 0.011
proteasomal protein catabolic process GO:0010498 2 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
response to glucose GO:0009749 3 0.011
nucleic acid templated transcription GO:0097659 181 0.011
ubiquitin dependent protein catabolic process GO:0006511 3 0.011
regulation of protein complex assembly GO:0043254 3 0.011
mesoderm development GO:0007498 88 0.011
central nervous system neuron differentiation GO:0021953 74 0.011
nuclear migration GO:0007097 3 0.010
calcium ion dependent exocytosis GO:0017156 1 0.010
response to uv GO:0009411 3 0.010
positive regulation of camp metabolic process GO:0030816 2 0.010
protein targeting to nucleus GO:0044744 3 0.010
forebrain development GO:0030900 96 0.010
single organism nuclear import GO:1902593 3 0.010
enzyme linked receptor protein signaling pathway GO:0007167 106 0.010
determination of left right asymmetry in lateral mesoderm GO:0003140 20 0.010
interspecies interaction between organisms GO:0044419 4 0.010
regulation of neural precursor cell proliferation GO:2000177 3 0.010
protein import GO:0017038 3 0.010
negative regulation of multi organism process GO:0043901 3 0.010
negative regulation of reproductive process GO:2000242 3 0.010

sc:d0319 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.171
nervous system disease DOID:863 0 0.042
organ system cancer DOID:0050686 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
cancer DOID:162 0 0.020
neurodegenerative disease DOID:1289 0 0.013
central nervous system disease DOID:331 0 0.013
muscular disease DOID:0080000 0 0.012
myopathy DOID:423 0 0.012
muscle tissue disease DOID:66 0 0.012
musculoskeletal system disease DOID:17 0 0.012