Danio rerio

0 known processes

setdb1a

SET domain, bifurcated 1a

(Aliases: wu:fc07d03,fc07d03,si:ch211-81a5.6,SETDB1)

setdb1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
methylation GO:0032259 22 0.770
Fly
chromatin modification GO:0016568 21 0.718
Fly
protein alkylation GO:0008213 13 0.635
Fly
macromolecule methylation GO:0043414 19 0.630
Fly
protein methylation GO:0006479 13 0.556
Fly
histone h4 k20 methylation GO:0034770 2 0.553
nitrogen compound metabolic process GO:0006807 319 0.546
Fly
histone methylation GO:0016571 13 0.545
Fly
histone lysine methylation GO:0034968 12 0.540
Fly
single organism metabolic process GO:0044710 217 0.520
Fly
nucleic acid metabolic process GO:0090304 244 0.484
Fly
organelle organization GO:0006996 227 0.441
Fly
histone h3 k9 methylation GO:0051567 5 0.437
Fly
regulation of gene expression GO:0010468 265 0.428
Fly
regulation of nitrogen compound metabolic process GO:0051171 251 0.406
Fly
histone h3 k36 methylation GO:0010452 2 0.366
single organism organelle organization GO:1902589 199 0.340
Fly
nucleobase containing compound metabolic process GO:0006139 274 0.333
Fly
chromosome organization GO:0051276 31 0.301
Fly
negative regulation of biological process GO:0048519 304 0.282
Fly
cellular biosynthetic process GO:0044249 286 0.281
Fly
dna catabolic process GO:0006308 1 0.256
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.248
Fly
regulation of multicellular organism growth GO:0040014 4 0.223
cellular macromolecule biosynthetic process GO:0034645 224 0.219
Fly
rna biosynthetic process GO:0032774 181 0.209
Fly
regulation of rna biosynthetic process GO:2001141 213 0.209
Fly
histone h3 k9 modification GO:0061647 5 0.209
Fly
regulation of transcription dna templated GO:0006355 213 0.204
Fly
cellular aromatic compound metabolic process GO:0006725 295 0.193
Fly
negative regulation of cellular metabolic process GO:0031324 77 0.182
Fly
chromatin organization GO:0006325 22 0.176
Fly
protein metabolic process GO:0019538 183 0.166
Fly
multicellular organism growth GO:0035264 4 0.162
covalent chromatin modification GO:0016569 20 0.161
Fly
biosynthetic process GO:0009058 294 0.160
Fly
macromolecule biosynthetic process GO:0009059 227 0.159
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.140
Fly
digestive system development GO:0055123 289 0.137
organic cyclic compound metabolic process GO:1901360 301 0.132
Fly
negative regulation of gene expression GO:0010629 65 0.129
Fly
histone h3 k4 methylation GO:0051568 2 0.127
nucleobase containing compound biosynthetic process GO:0034654 205 0.124
Fly
regulation of cellular metabolic process GO:0031323 320 0.122
Fly
negative regulation of macromolecule metabolic process GO:0010605 76 0.120
Fly
regulation of histone methylation GO:0031060 3 0.120
negative regulation of transcription dna templated GO:0045892 45 0.116
Fly
aromatic compound biosynthetic process GO:0019438 217 0.115
Fly
cellular component morphogenesis GO:0032989 336 0.113
regulation of biosynthetic process GO:0009889 250 0.112
Fly
transcription dna templated GO:0006351 181 0.111
Fly
response to stress GO:0006950 263 0.111
heterocycle biosynthetic process GO:0018130 215 0.110
Fly
negative regulation of cellular process GO:0048523 283 0.106
Fly
organic cyclic compound biosynthetic process GO:1901362 223 0.106
Fly
cellular nitrogen compound biosynthetic process GO:0044271 218 0.102
Fly
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.100
Fly
cellular nitrogen compound metabolic process GO:0034641 290 0.097
Fly
histone modification GO:0016570 20 0.097
Fly
peptidyl lysine trimethylation GO:0018023 1 0.095
regulation of primary metabolic process GO:0080090 311 0.093
Fly
negative regulation of metabolic process GO:0009892 86 0.084
Fly
heterocycle metabolic process GO:0046483 290 0.084
Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 59 0.082
Fly
transcription from rna polymerase ii promoter GO:0006366 80 0.081
cellular macromolecule metabolic process GO:0044260 391 0.079
Fly
organic substance biosynthetic process GO:1901576 289 0.077
Fly
nucleic acid templated transcription GO:0097659 181 0.071
Fly
cell morphogenesis GO:0000902 289 0.068
negative regulation of rna biosynthetic process GO:1902679 45 0.065
Fly
regulation of macromolecule biosynthetic process GO:0010556 225 0.062
Fly
peptidyl lysine methylation GO:0018022 3 0.062
Fly
digestive tract development GO:0048565 265 0.060
positive regulation of dna metabolic process GO:0051054 1 0.059
double strand break repair via homologous recombination GO:0000724 1 0.058
gene expression GO:0010467 252 0.056
Fly
negative regulation of biosynthetic process GO:0009890 55 0.055
Fly
dna metabolic process GO:0006259 27 0.055
Fly
regulation of rna metabolic process GO:0051252 224 0.054
Fly
cellular protein metabolic process GO:0044267 129 0.052
Fly
regulation of metabolic process GO:0019222 359 0.051
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 114 0.050
negative regulation of rna metabolic process GO:0051253 48 0.048
Fly
localization of cell GO:0051674 244 0.048
g2 dna damage checkpoint GO:0031572 3 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.046
regulation of cellular biosynthetic process GO:0031326 245 0.046
Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.046
Fly
somatic cell dna recombination GO:0016444 1 0.046
rna metabolic process GO:0016070 219 0.045
Fly
female sex differentiation GO:0046660 4 0.045
developmental growth GO:0048589 166 0.045
tube morphogenesis GO:0035239 349 0.044
intra s dna damage checkpoint GO:0031573 1 0.044
cilium organization GO:0044782 71 0.044
recombinational repair GO:0000725 1 0.044
retina development in camera type eye GO:0060041 146 0.043
cellular response to dna damage stimulus GO:0006974 24 0.043
positive regulation of cellular component biogenesis GO:0044089 3 0.043
regulation of protein complex assembly GO:0043254 3 0.042
cell part morphogenesis GO:0032990 246 0.040
meiotic nuclear division GO:0007126 4 0.040
Fly
regulation of macromolecule metabolic process GO:0060255 317 0.040
Fly
spermatid differentiation GO:0048515 2 0.039
heart development GO:0007507 313 0.039
cell projection morphogenesis GO:0048858 244 0.038
gastrulation GO:0007369 208 0.038
peptidyl serine phosphorylation GO:0018105 1 0.038
positive regulation of cell cycle GO:0045787 3 0.038
cellular response to external stimulus GO:0071496 2 0.037
g2 m transition of mitotic cell cycle GO:0000086 4 0.037
head development GO:0060322 303 0.036
double strand break repair GO:0006302 3 0.035
meiotic cell cycle process GO:1903046 3 0.034
peptidyl lysine dimethylation GO:0018027 1 0.034
immune system development GO:0002520 191 0.032
positive regulation of protein complex assembly GO:0031334 2 0.031
development of primary female sexual characteristics GO:0046545 4 0.031
regulation of histone h3 k9 methylation GO:0051570 2 0.030
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.030
Fly
cell cycle g2 m phase transition GO:0044839 4 0.030
connective tissue development GO:0061448 99 0.029
mesenchyme development GO:0060485 127 0.029
g1 s transition of mitotic cell cycle GO:0000082 1 0.029
negative regulation of dna metabolic process GO:0051053 4 0.028
neuron differentiation GO:0030182 353 0.028
regulation of nucleic acid templated transcription GO:1903506 213 0.028
Fly
macromolecular complex assembly GO:0065003 35 0.028
specification of symmetry GO:0009799 204 0.028
cell projection organization GO:0030030 284 0.028
dna alkylation GO:0006305 8 0.027
Fly
cellular protein modification process GO:0006464 100 0.027
Fly
response to external stimulus GO:0009605 264 0.027
female gonad development GO:0008585 4 0.027
macromolecular complex subunit organization GO:0043933 74 0.027
Fly
cellular component biogenesis GO:0044085 178 0.026
microtubule organizing center organization GO:0031023 1 0.026
protein modification process GO:0036211 100 0.026
Fly
cell cycle g1 s phase transition GO:0044843 1 0.025
mitotic dna damage checkpoint GO:0044773 4 0.025
dorsal motor nucleus of vagus nerve development GO:0021744 4 0.025
signal transduction GO:0007165 455 0.025
internal peptidyl lysine acetylation GO:0018393 2 0.025
telomere organization GO:0032200 1 0.025
cellular response to stress GO:0033554 62 0.025
positive regulation of chromosome organization GO:2001252 1 0.025
establishment of localization GO:0051234 244 0.024
dna templated transcription initiation GO:0006352 1 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 16 0.024
central nervous system development GO:0007417 387 0.024
male meiosis GO:0007140 2 0.024
cellular component assembly GO:0022607 170 0.023
determination of left right symmetry GO:0007368 179 0.023
cilium assembly GO:0042384 58 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
meiosis i GO:0007127 1 0.022
response to nutrient GO:0007584 3 0.022
immunoglobulin mediated immune response GO:0016064 3 0.021
peptidyl serine modification GO:0018209 2 0.021
macromolecule modification GO:0043412 111 0.021
Fly
immunoglobulin production GO:0002377 1 0.021
determination of heart left right asymmetry GO:0061371 117 0.021
regulation of multicellular organismal process GO:0051239 277 0.021
nucleic acid phosphodiester bond hydrolysis GO:0090305 6 0.021
cellular amine metabolic process GO:0044106 2 0.021
myeloid cell development GO:0061515 32 0.021
regulation of developmental process GO:0050793 247 0.021
b cell mediated immunity GO:0019724 3 0.021
cilium movement GO:0003341 26 0.020
negative regulation of cellular biosynthetic process GO:0031327 55 0.020
Fly
sensory organ development GO:0007423 393 0.020
cell substrate adhesion GO:0031589 4 0.020
sensory organ morphogenesis GO:0090596 200 0.020
cellular component movement GO:0006928 335 0.020
regulation of cellular component organization GO:0051128 86 0.019
cell morphogenesis involved in differentiation GO:0000904 195 0.019
heart morphogenesis GO:0003007 156 0.019
cellular macromolecular complex assembly GO:0034622 24 0.019
peptidyl lysine acetylation GO:0018394 2 0.019
response to abiotic stimulus GO:0009628 122 0.019
gamete generation GO:0007276 33 0.019
Fly
spermatid development GO:0007286 2 0.019
locomotion GO:0040011 313 0.019
cellular component assembly involved in morphogenesis GO:0010927 107 0.019
determination of bilateral symmetry GO:0009855 204 0.018
regulation of establishment of protein localization GO:0070201 4 0.018
immune system process GO:0002376 241 0.018
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 3 0.018
regulation of cellular amine metabolic process GO:0033238 0 0.018
regulation of stem cell differentiation GO:2000736 4 0.017
smooth muscle contraction GO:0006939 2 0.017
cellular response to extracellular stimulus GO:0031668 2 0.017
positive regulation of biological process GO:0048518 253 0.017
regulation of histone modification GO:0031056 5 0.016
cartilage development GO:0051216 96 0.016
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 4 0.016
b cell activation GO:0042113 2 0.016
zymogen activation GO:0031638 3 0.016
eye morphogenesis GO:0048592 144 0.016
cell motility GO:0048870 244 0.016
regulation of cellular ketone metabolic process GO:0010565 7 0.015
protein complex biogenesis GO:0070271 30 0.015
mitotic dna integrity checkpoint GO:0044774 4 0.015
sister chromatid cohesion GO:0007062 2 0.015
regulation of dna metabolic process GO:0051052 11 0.015
Fly
production of molecular mediator of immune response GO:0002440 2 0.015
eye development GO:0001654 277 0.015
regulation of chromatin organization GO:1902275 5 0.015
amine metabolic process GO:0009308 2 0.015
gene silencing GO:0016458 4 0.015
Fly
rna localization GO:0006403 4 0.015
protein acetylation GO:0006473 2 0.015
cardiac atrium development GO:0003230 4 0.015
embryo development ending in birth or egg hatching GO:0009792 271 0.015
regulation of protein catabolic process GO:0042176 1 0.015
cell migration GO:0016477 237 0.014
growth GO:0040007 174 0.014
atp catabolic process GO:0006200 4 0.014
regulation of gene expression epigenetic GO:0040029 11 0.014
Fly
cellular ketone metabolic process GO:0042180 11 0.014
cellular response to nutrient levels GO:0031669 2 0.014
regulation of response to extracellular stimulus GO:0032104 1 0.014
meiosis ii GO:0007135 1 0.014
response to chemical GO:0042221 320 0.014
meiotic chromosome segregation GO:0045132 3 0.014
peptidyl amino acid modification GO:0018193 16 0.014
Fly
regulation of dna recombination GO:0000018 2 0.014
stem cell maintenance GO:0019827 4 0.014
anterior posterior pattern specification GO:0009952 152 0.014
microtubule cytoskeleton organization involved in mitosis GO:1902850 1 0.013
dna methylation or demethylation GO:0044728 8 0.013
Fly
protein acylation GO:0043543 3 0.013
pancreas development GO:0031016 84 0.013
chromosome organization involved in meiosis GO:0070192 1 0.013
neuron projection morphogenesis GO:0048812 161 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
mitotic cell cycle GO:0000278 64 0.013
cellular localization GO:0051641 97 0.013
nucleocytoplasmic transport GO:0006913 4 0.013
internal protein amino acid acetylation GO:0006475 2 0.013
nucleoside monophosphate catabolic process GO:0009125 4 0.012
negative regulation of dna replication GO:0008156 2 0.012
positive regulation of dna templated transcription elongation GO:0032786 1 0.012
peptidyl lysine modification GO:0018205 5 0.012
Fly
exocrine pancreas development GO:0031017 28 0.012
embryonic organ development GO:0048568 381 0.012
regulation of tube size GO:0035150 2 0.012
adult behavior GO:0030534 2 0.012
regulation of blood vessel size GO:0050880 2 0.012
multi organism process GO:0051704 134 0.012
Fly
cellular response to starvation GO:0009267 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
response to endogenous stimulus GO:0009719 83 0.012
regulation of microtubule cytoskeleton organization GO:0070507 3 0.012
aging GO:0007568 2 0.012
larval development GO:0002164 2 0.012
non recombinational repair GO:0000726 2 0.012
camera type eye development GO:0043010 222 0.012
organelle assembly GO:0070925 110 0.012
translational initiation GO:0006413 3 0.011
cell cycle process GO:0022402 53 0.011
regulation of localization GO:0032879 104 0.011
photoreceptor cell outer segment organization GO:0035845 9 0.011
cilium movement involved in cell motility GO:0060294 3 0.011
organic acid metabolic process GO:0006082 31 0.011
ovarian follicle development GO:0001541 2 0.011
hemopoiesis GO:0030097 183 0.011
regulation of cell activation GO:0050865 1 0.011
stem cell division GO:0017145 1 0.011
Fly
regulation of translational initiation GO:0006446 1 0.011
purine nucleoside monophosphate catabolic process GO:0009128 4 0.011
multi organism reproductive process GO:0044703 36 0.011
Fly
digestive tract morphogenesis GO:0048546 231 0.010
small molecule metabolic process GO:0044281 77 0.010
regulation of biological quality GO:0065008 263 0.010
neuron development GO:0048666 262 0.010
intracellular mrna localization GO:0008298 1 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
ribonucleoside monophosphate catabolic process GO:0009158 4 0.010
regulation of dna replication GO:0006275 3 0.010
lipid storage GO:0019915 1 0.010
protein complex assembly GO:0006461 30 0.010
germ cell migration GO:0008354 8 0.010
telomere maintenance GO:0000723 1 0.010
spindle assembly involved in mitosis GO:0090307 1 0.010
regulation of intracellular protein transport GO:0033157 3 0.010
porphyrin containing compound metabolic process GO:0006778 10 0.010
dna modification GO:0006304 8 0.010
Fly
homeostatic process GO:0042592 142 0.010
forebrain development GO:0030900 96 0.010
positive regulation of chromatin modification GO:1903310 1 0.010

setdb1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
cancer DOID:162 0 0.031
organ system cancer DOID:0050686 0 0.031
disease of cellular proliferation DOID:14566 0 0.031
immune system disease DOID:2914 0 0.018
hematopoietic system disease DOID:74 0 0.018
bone marrow disease DOID:4961 0 0.018
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.012
thoracic cancer DOID:5093 0 0.010