Danio rerio

0 known processes

tsc22d2

TSC22 domain family 2 and TSC22 domain family, member 2

(Aliases: zgc:92475,cb869,wu:fa55e04,kiaa0669,id:ibd5097)

tsc22d2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent macromolecule catabolic process GO:0043632 3 0.351
signal transduction GO:0007165 455 0.329
larval development GO:0002164 2 0.196
regulation of multicellular organismal process GO:0051239 277 0.170
nucleic acid templated transcription GO:0097659 181 0.167
modification dependent protein catabolic process GO:0019941 3 0.166
ubiquitin dependent protein catabolic process GO:0006511 3 0.156
nucleobase containing compound metabolic process GO:0006139 274 0.144
cellular macromolecule metabolic process GO:0044260 391 0.138
rna biosynthetic process GO:0032774 181 0.138
regulation of metabolic process GO:0019222 359 0.137
establishment of protein localization to organelle GO:0072594 4 0.131
regulation of filopodium assembly GO:0051489 2 0.130
stem cell proliferation GO:0072089 4 0.121
protein polyubiquitination GO:0000209 4 0.121
cell surface receptor signaling pathway GO:0007166 325 0.112
regulation of rna metabolic process GO:0051252 224 0.111
proteasomal protein catabolic process GO:0010498 2 0.110
generation of neurons GO:0048699 385 0.102
gene expression GO:0010467 252 0.099
positive regulation of transport GO:0051050 2 0.099
nucleocytoplasmic transport GO:0006913 4 0.093
cellular protein catabolic process GO:0044257 4 0.087
heterocycle metabolic process GO:0046483 290 0.086
regulation of transcription dna templated GO:0006355 213 0.081
blood vessel development GO:0001568 246 0.080
regulation of cellular metabolic process GO:0031323 320 0.080
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.078
nitrogen compound metabolic process GO:0006807 319 0.077
regulation of macromolecule biosynthetic process GO:0010556 225 0.073
cellular macromolecule biosynthetic process GO:0034645 224 0.073
neuron differentiation GO:0030182 353 0.071
heterocycle biosynthetic process GO:0018130 215 0.070
negative regulation of biological process GO:0048519 304 0.065
microtubule organizing center organization GO:0031023 1 0.065
ameboidal type cell migration GO:0001667 143 0.065
regulation of primary metabolic process GO:0080090 311 0.063
nuclear transport GO:0051169 4 0.062
vasculature development GO:0001944 278 0.061
organelle assembly GO:0070925 110 0.061
digestive tract development GO:0048565 265 0.059
neuroblast proliferation GO:0007405 2 0.058
transport GO:0006810 220 0.058
rna metabolic process GO:0016070 219 0.056
rna localization GO:0006403 4 0.054
meiotic cell cycle process GO:1903046 3 0.054
single organism localization GO:1902578 225 0.053
regulation of biosynthetic process GO:0009889 250 0.053
positive regulation of cellular catabolic process GO:0031331 3 0.052
cellular component movement GO:0006928 335 0.050
cognition GO:0050890 1 0.050
olfactory lobe development GO:0021988 4 0.050
transcription dna templated GO:0006351 181 0.049
digestive system development GO:0055123 289 0.049
nucleobase containing compound biosynthetic process GO:0034654 205 0.049
organic cyclic compound biosynthetic process GO:1901362 223 0.049
negative regulation of protein kinase activity GO:0006469 4 0.049
spermatid differentiation GO:0048515 2 0.048
regulation of multicellular organismal development GO:2000026 223 0.048
regulation of cell projection assembly GO:0060491 4 0.047
nuclear import GO:0051170 3 0.047
nucleic acid transport GO:0050657 2 0.047
adult behavior GO:0030534 2 0.047
rna transport GO:0050658 2 0.047
protein modification process GO:0036211 100 0.047
neuron neuron synaptic transmission GO:0007270 1 0.046
regulation of nitrogen compound metabolic process GO:0051171 251 0.044
organic cyclic compound metabolic process GO:1901360 301 0.044
protein metabolic process GO:0019538 183 0.044
cellular nitrogen compound metabolic process GO:0034641 290 0.044
cellular nitrogen compound biosynthetic process GO:0044271 218 0.044
negative regulation of cellular process GO:0048523 283 0.043
aromatic compound biosynthetic process GO:0019438 217 0.043
cellular aromatic compound metabolic process GO:0006725 295 0.042
establishment of localization GO:0051234 244 0.042
regulation of nucleic acid templated transcription GO:1903506 213 0.042
meiotic chromosome segregation GO:0045132 3 0.041
gastrulation GO:0007369 208 0.041
natural killer cell mediated immunity GO:0002228 1 0.041
cell motility GO:0048870 244 0.041
regulation of signaling GO:0023051 235 0.041
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.040
macromolecule biosynthetic process GO:0009059 227 0.040
protein targeting to nucleus GO:0044744 3 0.039
maintenance of location GO:0051235 4 0.039
positive regulation of macromolecule metabolic process GO:0010604 93 0.039
centrosome cycle GO:0007098 1 0.039
organic substance biosynthetic process GO:1901576 289 0.038
digestive tract morphogenesis GO:0048546 231 0.038
locomotion GO:0040011 313 0.038
negative regulation of protein phosphorylation GO:0001933 4 0.038
single organism cellular localization GO:1902580 46 0.038
positive regulation of cellular process GO:0048522 201 0.038
cellular response to chemical stimulus GO:0070887 157 0.037
single organism nuclear import GO:1902593 3 0.036
regulation of macromolecule metabolic process GO:0060255 317 0.036
stem cell division GO:0017145 1 0.036
nucleic acid metabolic process GO:0090304 244 0.036
protein localization to nucleus GO:0034504 3 0.035
neuron projection development GO:0031175 180 0.035
neurotransmitter transport GO:0006836 2 0.035
heart development GO:0007507 313 0.034
wnt signaling pathway GO:0016055 80 0.034
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.034
organic substance transport GO:0071702 58 0.034
cellular protein modification process GO:0006464 100 0.033
growth GO:0040007 174 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 48 0.033
neurotransmitter secretion GO:0007269 2 0.032
establishment of localization in cell GO:0051649 77 0.032
natural killer cell mediated cytotoxicity GO:0042267 1 0.032
regulation of receptor mediated endocytosis GO:0048259 4 0.032
embryo development ending in birth or egg hatching GO:0009792 271 0.032
response to chemical GO:0042221 320 0.031
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.031
regulation of cell communication GO:0010646 232 0.030
macromolecule localization GO:0033036 54 0.030
cell projection organization GO:0030030 284 0.030
compound eye development GO:0048749 2 0.030
lipid storage GO:0019915 1 0.030
localization of cell GO:0051674 244 0.030
cellular protein metabolic process GO:0044267 129 0.029
mrna export from nucleus GO:0006406 1 0.029
cell projection assembly GO:0030031 64 0.029
negative regulation of metabolic process GO:0009892 86 0.029
microtubule based process GO:0007017 60 0.028
regulation of protein ubiquitination GO:0031396 3 0.028
system process GO:0003008 185 0.028
regulation of organ growth GO:0046620 3 0.028
protein import into nucleus GO:0006606 3 0.028
regulation of protein catabolic process GO:0042176 1 0.027
somitogenesis GO:0001756 87 0.027
regulation of dendrite morphogenesis GO:0048814 3 0.027
negative regulation of cellular biosynthetic process GO:0031327 55 0.027
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.027
multicellular organism growth GO:0035264 4 0.027
circadian sleep wake cycle process GO:0022410 2 0.027
tube morphogenesis GO:0035239 349 0.027
cell migration GO:0016477 237 0.026
smooth muscle tissue development GO:0048745 1 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.026
transcription from rna polymerase ii promoter GO:0006366 80 0.026
hematopoietic or lymphoid organ development GO:0048534 191 0.026
muscle organ development GO:0007517 101 0.026
mitotic cell cycle GO:0000278 64 0.026
microtubule cytoskeleton organization GO:0000226 33 0.025
cellular localization GO:0051641 97 0.025
meiosis i GO:0007127 1 0.025
single organism membrane fusion GO:0044801 2 0.025
single organism transport GO:0044765 206 0.025
mrna transport GO:0051028 2 0.025
meiotic nuclear division GO:0007126 4 0.024
cell part morphogenesis GO:0032990 246 0.024
circadian sleep wake cycle GO:0042745 2 0.024
developmental growth GO:0048589 166 0.024
macromolecule modification GO:0043412 111 0.023
i kappab kinase nf kappab signaling GO:0007249 4 0.023
aging GO:0007568 2 0.023
syncytium formation GO:0006949 12 0.023
negative regulation of macromolecule metabolic process GO:0010605 76 0.023
cellular response to endogenous stimulus GO:0071495 68 0.023
regulation of cellular macromolecule biosynthetic process GO:2000112 222 0.023
regulation of endocytosis GO:0030100 7 0.023
regulation of protein binding GO:0043393 3 0.023
multicellular organismal reproductive process GO:0048609 35 0.022
g protein coupled receptor signaling pathway GO:0007186 74 0.022
regulation of production of molecular mediator of immune response GO:0002700 1 0.022
morphogenesis of an epithelium GO:0002009 333 0.022
circadian sleep wake cycle sleep GO:0050802 1 0.022
nucleobase containing compound transport GO:0015931 2 0.022
head development GO:0060322 303 0.022
death GO:0016265 121 0.022
regulation of multicellular organism growth GO:0040014 4 0.022
regulation of cytokine production GO:0001817 3 0.022
positive regulation of biological process GO:0048518 253 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 42 0.022
positive regulation of metabolic process GO:0009893 108 0.021
regulation of signal transduction GO:0009966 225 0.021
immune system process GO:0002376 241 0.021
phagocytosis GO:0006909 3 0.021
positive regulation of exocytosis GO:0045921 1 0.021
negative regulation of synapse assembly GO:0051964 2 0.021
negative regulation of cytokine production GO:0001818 1 0.020
macromolecular complex subunit organization GO:0043933 74 0.020
muscle cell differentiation GO:0042692 139 0.020
regulation of cellular component organization GO:0051128 86 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
cell projection morphogenesis GO:0048858 244 0.020
regulation of rna biosynthetic process GO:2001141 213 0.020
morphogenesis of an epithelial sheet GO:0002011 49 0.020
enzyme linked receptor protein signaling pathway GO:0007167 106 0.020
cellular biosynthetic process GO:0044249 286 0.020
spermatid development GO:0007286 2 0.020
neuron projection morphogenesis GO:0048812 161 0.020
peptidyl serine modification GO:0018209 2 0.020
hemopoiesis GO:0030097 183 0.020
regulation of synaptic plasticity GO:0048167 1 0.020
negative regulation of signal transduction GO:0009968 94 0.019
histone lysine demethylation GO:0070076 2 0.019
cellular component morphogenesis GO:0032989 336 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
hypothalamus cell differentiation GO:0021979 4 0.019
establishment of rna localization GO:0051236 3 0.019
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.019
positive regulation of i kappab kinase nf kappab signaling GO:0043123 3 0.018
regulation of biological quality GO:0065008 263 0.018
neuromast development GO:0048884 46 0.018
central nervous system development GO:0007417 387 0.018
cell killing GO:0001906 2 0.018
epiboly involved in gastrulation with mouth forming second GO:0055113 35 0.017
regulation of stem cell proliferation GO:0072091 2 0.017
cortical cytoskeleton organization GO:0030865 1 0.017
regulation of neuronal synaptic plasticity GO:0048168 1 0.017
regionalization GO:0003002 274 0.017
regulation of neural precursor cell proliferation GO:2000177 3 0.017
immune system development GO:0002520 191 0.017
small molecule metabolic process GO:0044281 77 0.017
regulation of stem cell differentiation GO:2000736 4 0.017
positive regulation of muscle cell differentiation GO:0051149 1 0.017
regulation of protein targeting GO:1903533 2 0.017
regulation of purine nucleotide catabolic process GO:0033121 2 0.017
chordate embryonic development GO:0043009 271 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.016
angiogenesis GO:0001525 158 0.016
neural tube development GO:0021915 62 0.016
sleep GO:0030431 1 0.016
organelle localization GO:0051640 49 0.016
regulation of erk1 and erk2 cascade GO:0070372 4 0.016
cellular response to organic substance GO:0071310 105 0.016
negative regulation of biosynthetic process GO:0009890 55 0.016
peripheral nervous system development GO:0007422 55 0.016
dna templated transcription elongation GO:0006354 3 0.016
protein k48 linked ubiquitination GO:0070936 1 0.016
chemosensory behavior GO:0007635 1 0.016
single organism organelle organization GO:1902589 199 0.015
blood vessel morphogenesis GO:0048514 216 0.015
small gtpase mediated signal transduction GO:0007264 8 0.015
negative regulation of kinase activity GO:0033673 4 0.015
positive regulation of catabolic process GO:0009896 4 0.015
histone demethylation GO:0016577 2 0.015
establishment or maintenance of cell polarity GO:0007163 29 0.015
olfactory bulb development GO:0021772 4 0.015
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 1 0.015
regulation of synapse organization GO:0050807 3 0.015
epithelial cell morphogenesis GO:0003382 2 0.015
membrane invagination GO:0010324 1 0.015
production of molecular mediator of immune response GO:0002440 2 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 4 0.015
guanosine containing compound metabolic process GO:1901068 4 0.015
muscle cell migration GO:0014812 4 0.014
protein targeting to vacuole GO:0006623 1 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 48 0.014
neural precursor cell proliferation GO:0061351 20 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 59 0.014
cell fate commitment GO:0045165 99 0.014
cell cycle g1 s phase transition GO:0044843 1 0.014
negative regulation of signaling GO:0023057 96 0.014
negative regulation of cell communication GO:0010648 96 0.014
receptor internalization GO:0031623 2 0.014
odontogenesis of dentin containing tooth GO:0042475 1 0.014
positive regulation of immune effector process GO:0002699 3 0.014
protein dealkylation GO:0008214 2 0.014
gtp metabolic process GO:0046039 4 0.014
cellular component assembly GO:0022607 170 0.014
cell morphogenesis GO:0000902 289 0.014
intracellular transport GO:0046907 32 0.014
establishment of synaptic vesicle localization GO:0097480 1 0.013
exocytosis GO:0006887 1 0.013
apoptotic process GO:0006915 116 0.013
g1 s transition of mitotic cell cycle GO:0000082 1 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.013
multi organism process GO:0051704 134 0.013
synaptic vesicle endocytosis GO:0048488 1 0.013
regulation of cellular protein catabolic process GO:1903362 1 0.013
establishment of organelle localization GO:0051656 45 0.013
axon ensheathment in central nervous system GO:0032291 2 0.013
specification of symmetry GO:0009799 204 0.013
stem cell maintenance GO:0019827 4 0.013
protein demethylation GO:0006482 2 0.013
cellular component biogenesis GO:0044085 178 0.013
cell cycle GO:0007049 93 0.013
cellular amine metabolic process GO:0044106 2 0.013
negative regulation of rna metabolic process GO:0051253 48 0.013
negative regulation of intracellular transport GO:0032387 3 0.013
positive regulation of jnk cascade GO:0046330 3 0.013
regulation of dendrite development GO:0050773 3 0.013
positive regulation of canonical wnt signaling pathway GO:0090263 4 0.013
regulation of cellular amine metabolic process GO:0033238 0 0.013
synaptic growth at neuromuscular junction GO:0051124 2 0.013
cell cycle process GO:0022402 53 0.013
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.013
guanosine containing compound catabolic process GO:1901069 2 0.013
canonical wnt signaling pathway GO:0060070 48 0.013
positive regulation of ras protein signal transduction GO:0046579 1 0.012
regulation of cardiac muscle tissue development GO:0055024 1 0.012
intracellular signal transduction GO:0035556 85 0.012
cytoplasm organization GO:0007028 4 0.012
protein import GO:0017038 3 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 69 0.012
ribosomal small subunit biogenesis GO:0042274 2 0.012
taxis GO:0042330 109 0.012
branching morphogenesis of a nerve GO:0048755 4 0.012
single organism metabolic process GO:0044710 217 0.012
positive regulation of protein kinase b signaling GO:0051897 1 0.012
chromosome organization GO:0051276 31 0.012
regulation of gene expression GO:0010468 265 0.012
glial cell migration GO:0008347 3 0.012
regulation of circadian rhythm GO:0042752 4 0.012
cytoskeleton organization GO:0007010 96 0.012
gtp catabolic process GO:0006184 2 0.012
regulation of growth rate GO:0040009 1 0.012
regulation of intracellular protein transport GO:0033157 3 0.012
regulation of neurological system process GO:0031644 2 0.011
positive regulation of cytoskeleton organization GO:0051495 3 0.011
regulation of dna damage response signal transduction by p53 class mediator GO:0043516 4 0.011
regulation of protein import into nucleus GO:0042306 2 0.011
rna export from nucleus GO:0006405 1 0.011
regulation of response to stimulus GO:0048583 269 0.011
establishment of epithelial cell polarity GO:0090162 2 0.011
cellular amino acid metabolic process GO:0006520 7 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 69 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 4 0.011
tissue migration GO:0090130 37 0.011
eye development GO:0001654 277 0.011
regulation of response to biotic stimulus GO:0002831 2 0.011
response to endogenous stimulus GO:0009719 83 0.011
cell substrate adhesion GO:0031589 4 0.011
regulation of neurotransmitter transport GO:0051588 1 0.011
transcription from rna polymerase iii promoter GO:0006383 1 0.011
germ line stem cell maintenance GO:0030718 2 0.011
sensory organ development GO:0007423 393 0.011
central nervous system neuron development GO:0021954 29 0.011
organelle organization GO:0006996 227 0.011
synaptic vesicle localization GO:0097479 1 0.011
negative regulation of response to stimulus GO:0048585 104 0.011
positive regulation of neuron apoptotic process GO:0043525 1 0.011
adherens junction organization GO:0034332 4 0.011
locomotory behavior GO:0007626 34 0.011
segmentation GO:0035282 97 0.011
organonitrogen compound metabolic process GO:1901564 74 0.011
biosynthetic process GO:0009058 294 0.010
axonogenesis GO:0007409 152 0.010
regulation of nucleocytoplasmic transport GO:0046822 2 0.010
histone modification GO:0016570 20 0.010
behavior GO:0007610 74 0.010
chromatin organization GO:0006325 22 0.010
startle response GO:0001964 4 0.010
negative regulation of multicellular organismal process GO:0051241 69 0.010
organic acid metabolic process GO:0006082 31 0.010
regulation of defense response to virus by host GO:0050691 1 0.010
macromolecule catabolic process GO:0009057 15 0.010

tsc22d2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.085
disease of metabolism DOID:0014667 0 0.014
nervous system disease DOID:863 0 0.013
organ system cancer DOID:0050686 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
cancer DOID:162 0 0.012
immune system disease DOID:2914 0 0.010