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Danio rerio

2 genes annotated in zebrafish

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histone demethylation

GO:0016577

The modification of histones by removal of methyl groups.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "histone demethylation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "histone demethylation" (in gray)

Name	Description	Probability	Func Analog Organism
wu:fi04c06	wu:fi04c06	0.379
kdm4b	lysine (K)-specific demethylase 4B	0.351	Yeast Fly
LOC100536021	spectrin beta chain, brain 1-like	0.282
wu:fj55b04	wu:fj55b04	0.215
ankrd12	ankyrin repeat domain 12	0.202
gpatch8	G patch domain containing 8	0.180
ash1l	ash1 (absent, small, or homeotic)-like (Drosophila)	0.126
brap	BRCA1 associated protein	0.108
smurf2	SMAD specific E3 ubiquitin protein ligase 2	0.092
fbxl5	F-box and leucine-rich repeat protein 5	0.086
si:dkey-21n12.1	si:dkey-21n12.1	0.083
phf2	PHD finger protein 2	0.079	Mouse
btg1	B-cell translocation gene 1	0.071
npepps	aminopeptidase puromycin sensitive	0.063
ralgapa1	Ral GTPase activating protein, alpha subunit 1 (catalytic)	0.062
phrf1	PHD and ring finger domains 1	0.059
lmbrd2b	LMBR1 domain containing 2b	0.056
tecpr2	tectonin beta-propeller repeat containing 2	0.053
zgc:162740	zgc:162740	0.052
skia	nuclear oncoprotein skia	0.047
rpap2	RNA polymerase II associated protein 2	0.041
oxsr1a	oxidative-stress responsive 1a	0.041
actr8	ARP8 actin-related protein 8 homolog (yeast)	0.040
si:ch211-57k11.10	si:ch211-57k11.10	0.039
fcho2	FCH domain only 2	0.038
supt6h	suppressor of Ty 6 homolog	0.037
nsun5	NOP2/Sun domain family, member 5	0.037
tyw3	tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)	0.035
nvl	nuclear VCP-like	0.035
fxr2	fragile X mental retardation, autosomal homolog 2	0.035
zgc:113421	zgc:113421	0.034
ptprfb	protein tyrosine phosphatase, receptor type, f, b	0.033
ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.033
zgc:101761	zgc:101761	0.033
ptena	phosphatase and tensin homolog A	0.032
nrp2b	neuropilin 2b	0.032
trmt5	TRM5 tRNA methyltransferase 5 homolog (S. cerevisiae)	0.032
wu:fa07b03	wu:fa07b03	0.032
fam192a	family with sequence similarity 192, member A	0.032
kidins220b	kinase D-interacting substrate of 220b	0.030
ints1	integrator complex subunit 1	0.029
mbnl2	muscleblind-like 2 (Drosophila)	0.028
pcmtd1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	0.027
si:dkeyp-94h10.5	si:dkeyp-94h10.5	0.027
sb:cb134	sb:cb134	0.027
tsc1	tuberous sclerosis 1	0.026
utp23	UTP23, small subunit (SSU) processome component, homolog (yeast)	0.026
ppp3cca	protein phosphatase 3, catalytic subunit, gamma isozyme, a	0.026
kdm5ba	lysine (K)-specific demethylase 5Ba	0.026	Human Mouse
midn	midnolin	0.026
rnf41	ring finger protein 41	0.025
peli1b	pellino homolog 1b (Drosophila)	0.024
exoc7	exocyst complex component 7	0.024
nova2	neuro-oncological ventral antigen 2	0.023
LOC100331141	ATP synthase subunit s-like protein-like	0.023
ikbkapl	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein like	0.023
ep300b	E1A binding protein p300 b	0.023
si:dkeyp-89d7.1	si:dkeyp-89d7.1	0.023
rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.023
si:dkey-175m17.8	si:dkey-175m17.8	0.023
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.022
mical3	flavoprotein oxidoreductase MICAL3	0.022
strn3	striatin, calmodulin binding protein 3	0.022
zgc:92834	zgc:92834	0.022
apc	adenomatosis polyposis coli	0.021
kdm1a	lysine (K)-specific demethylase 1a	0.021
wwp2	WW domain containing E3 ubiquitin protein ligase 2	0.021
cltca	clathrin, heavy polypeptide a (Hc)	0.020
pdcd4b	programmed cell death 4b	0.020
abca3	ATP-binding cassette, sub-family A (ABC1), member 3	0.020
zgc:114097	zgc:114097	0.020
dohh	deoxyhypusine hydroxylase/monooxygenase	0.020
abca5	ATP-binding cassette, sub-family A (ABC1), member 5	0.020
med18	mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)	0.020
clstn1	calsyntenin 1	0.020
elf2a	E74-like factor 2a (ets domain transcription factor)	0.019
nfia	nuclear factor I/A	0.019
exosc2	exosome component 2	0.019
rnf146	ring finger protein 146	0.019
cask	calcium/calmodulin-dependent serine protein kinase	0.019
smn1	survival motor neuron 1	0.019
tiprl	TIP41, TOR signaling pathway regulator-like (S. cerevisiae)	0.018
macf1	microtubule-actin crosslinking factor 1	0.018
spna2	spectrin alpha 2	0.018
mpped2	metallophosphoesterase domain containing 2	0.017
brd3b	bromodomain containing 3b	0.017
otud5a	OTU domain containing 5a	0.017
zgc:77407	zgc:77407	0.017
myef2	myelin expression factor 2	0.017
LOC555713	hypothetical LOC555713	0.017
znf148	zinc finger protein 148	0.016
fam203a	family with sequence similarity 203, member A	0.016
eef2k	elongation factor-2 kinase	0.016
mapk3	mitogen-activated protein kinase 3	0.016
im:7163548	im:7163548	0.016
brd8	bromodomain containing 8	0.016
c1orf109	c1orf109 homolog (H. sapiens)	0.015
nt5dc2	5'-nucleotidase domain containing 2	0.015
golgb1	golgi autoantigen, golgin subfamily b, macrogolgin (with transmembrane signal), 1	0.015
tsc22d2	TSC22 domain family 2 and TSC22 domain family, member 2	0.015
thoc2	THO complex 2	0.015
zgc:110084	zgc:110084	0.014
clasp2	cytoplasmic linker associated protein 2	0.014
si:dkey-11e23.5	si:dkey-11e23.5	0.014
siah1	seven in absentia homolog 1 (Drosophila)	0.014
ncdn	neurochondrin	0.014
zgc:152851	zgc:152851	0.014
nkx2.3	NK2 transcription factor related 3	0.014
hoxb6b	homeo box B6b	0.013
zgc:101130	zgc:101130	0.013
fmr1	fragile X mental retardation 1	0.013
b3galt2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2	0.013
LOC100330345	utrophin-like	0.013
sall1a	sal-like 1a (Drosophila)	0.013
ppp3r1b	protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b	0.013
atp1b3a	ATPase, Na+/K+ transporting, beta 3a polypeptide	0.013
si:ch211-173p18.3	si:ch211-173p18.3	0.012
ube4b	ubiquitination factor E4B, UFD2 homolog (S. cerevisiae)	0.012
zgc:152984	zgc:152984	0.012
si:dkeyp-20g2.6	si:dkeyp-20g2.6	0.012
tada2a	transcriptional adaptor 2A	0.012
si:dkey-230p4.1	si:dkey-230p4.1	0.012
arid4a	AT rich interactive domain 4A (RBP1-like)	0.012
six1a	sine oculis homeobox homolog 1a	0.012
noc3l	nucleolar complex associated 3 homolog (S. cerevisiae)	0.012
ift88	intraflagellar transport 88 homolog	0.012
prdm2b	PR domain containing 2, with ZNF domain b	0.012
ccng2	cyclin G2	0.012
bsk146	brain specific kinase 146	0.012
auts2	autism susceptibility candidate 2	0.011
thrb	thyroid hormone receptor beta	0.011
kif5bb	kinesin family member 5B, b	0.011
trim24	tripartite motif-containing 24	0.011
usp25	ubiquitin specific protease 25	0.011
csnk1g2a	casein kinase 1, gamma 2a	0.011
senp6a	SUMO1/sentrin specific peptidase 6a	0.011
adam23a	a disintegrin and metallopeptidase domain 23a	0.011
rorcb	RAR-related orphan receptor C b	0.011
zgc:101748	zgc:101748	0.011
wu:fc48e01	wu:fc48e01	0.011
fbln4	fibulin 4	0.011
LOC569473	anaphase-promoting complex subunit 13-like	0.011
LOC555630	mitochondrial ribonuclease P protein 3-like	0.011
cutl1	cut-like 1 (Drosophila)	0.011
ncor2	nuclear receptor co-repressor 2	0.011
ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.011
sltm	SAFB-like, transcription modulator	0.011
si:ch211-146l10.2	si:ch211-146l10.2	0.011
wdr46	WD repeat domain 46	0.011
si:dkeyp-38g8.5	si:dkeyp-38g8.5	0.011
zgc:103670	zgc:103670	0.011
ctu2	cytosolic thiouridylase subunit 2 homolog (S. pombe)	0.010
zgc:153061	zgc:153061	0.010
zgc:153012	zgc:153012	0.010
cited3	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 3	0.010
LOC100005267	RING finger protein 122-like	0.010