Danio rerio

0 known processes

tssc1

tumor suppressing subtransferable candidate 1

(Aliases: zgc:101720)

tssc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fatty acid catabolic process GO:0009062 1 0.116
larval development GO:0002164 2 0.108
aging GO:0007568 2 0.088
membrane fusion GO:0061025 2 0.077
guanosine containing compound metabolic process GO:1901068 4 0.075
positive regulation of apoptotic signaling pathway GO:2001235 1 0.075
lipid storage GO:0019915 1 0.067
maintenance of location GO:0051235 4 0.061
monocarboxylic acid catabolic process GO:0072329 3 0.055
gtp metabolic process GO:0046039 4 0.051
signal transduction GO:0007165 455 0.051
fatty acid beta oxidation GO:0006635 1 0.050
embryo development ending in birth or egg hatching GO:0009792 271 0.050
regulation of cellular metabolic process GO:0031323 320 0.049
regulation of extrinsic apoptotic signaling pathway GO:2001236 3 0.047
regulation of cell communication GO:0010646 232 0.046
regulation of protein transport GO:0051223 3 0.046
carboxylic acid catabolic process GO:0046395 3 0.046
negative regulation of protein kinase activity GO:0006469 4 0.046
phagocytosis GO:0006909 3 0.045
lateral inhibition GO:0046331 1 0.045
adult behavior GO:0030534 2 0.044
multicellular organism growth GO:0035264 4 0.044
amine metabolic process GO:0009308 2 0.044
gtp catabolic process GO:0006184 2 0.043
regulation of signal transduction GO:0009966 225 0.043
regulation of cellular amine metabolic process GO:0033238 0 0.043
guanosine containing compound catabolic process GO:1901069 2 0.041
positive regulation of cellular catabolic process GO:0031331 3 0.041
negative regulation of protein phosphorylation GO:0001933 4 0.041
ubiquitin dependent protein catabolic process GO:0006511 3 0.039
positive regulation of transport GO:0051050 2 0.038
cellular nitrogen compound metabolic process GO:0034641 290 0.038
regulation of protein complex assembly GO:0043254 3 0.038
cognition GO:0050890 1 0.037
regulation of synapse organization GO:0050807 3 0.037
protein polymerization GO:0051258 4 0.037
protein localization to plasma membrane GO:0072659 1 0.037
regulation of purine nucleotide catabolic process GO:0033121 2 0.036
lipid catabolic process GO:0016042 4 0.036
regulation of reproductive process GO:2000241 4 0.036
oxoacid metabolic process GO:0043436 31 0.036
fatty acid oxidation GO:0019395 1 0.035
positive regulation of catabolic process GO:0009896 4 0.035
single organism membrane fusion GO:0044801 2 0.034
cellular amine metabolic process GO:0044106 2 0.033
cytokinesis GO:0000910 3 0.033
cellular aromatic compound metabolic process GO:0006725 295 0.033
regulation of oocyte development GO:0060281 3 0.033
organelle organization GO:0006996 227 0.033
peptide metabolic process GO:0006518 1 0.033
synaptic growth at neuromuscular junction GO:0051124 2 0.032
positive regulation of cellular component biogenesis GO:0044089 3 0.032
regulation of sodium ion transport GO:0002028 2 0.032
regulation of primary metabolic process GO:0080090 311 0.032
regulation of establishment of protein localization GO:0070201 4 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.032
regulation of cellular carbohydrate metabolic process GO:0010675 4 0.031
cellular ketone metabolic process GO:0042180 11 0.031
cellular amide metabolic process GO:0043603 4 0.031
organic acid metabolic process GO:0006082 31 0.031
organic acid catabolic process GO:0016054 3 0.031
cellular lipid catabolic process GO:0044242 3 0.031
epithelial cell differentiation GO:0030855 116 0.031
cellular carbohydrate metabolic process GO:0044262 4 0.030
carboxylic acid metabolic process GO:0019752 22 0.030
regulation of carbohydrate metabolic process GO:0006109 4 0.030
single organism metabolic process GO:0044710 217 0.030
negative regulation of cellular catabolic process GO:0031330 3 0.030
negative regulation of biological process GO:0048519 304 0.030
mitochondrion organization GO:0007005 4 0.030
vasculature development GO:0001944 278 0.030
cell projection organization GO:0030030 284 0.029
lipid oxidation GO:0034440 1 0.029
small molecule metabolic process GO:0044281 77 0.028
phosphorus metabolic process GO:0006793 109 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.028
positive regulation of cell cycle GO:0045787 3 0.028
regulation of mitochondrion organization GO:0010821 1 0.028
cell projection morphogenesis GO:0048858 244 0.028
cellular protein catabolic process GO:0044257 4 0.028
regulation of synapse assembly GO:0051963 3 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 1 0.028
regulation of macromolecule metabolic process GO:0060255 317 0.028
regulation of signaling GO:0023051 235 0.028
maternal determination of anterior posterior axis embryo GO:0008358 4 0.028
exocytosis GO:0006887 1 0.028
regulation of dendrite development GO:0050773 3 0.028
organonitrogen compound metabolic process GO:1901564 74 0.027
regulation of protein catabolic process GO:0042176 1 0.027
adherens junction organization GO:0034332 4 0.027
establishment of protein localization to organelle GO:0072594 4 0.027
protein secretion GO:0009306 1 0.027
organic cyclic compound metabolic process GO:1901360 301 0.027
regulation of metabolic process GO:0019222 359 0.027
organelle fusion GO:0048284 3 0.027
extrinsic apoptotic signaling pathway GO:0097191 3 0.026
heterocycle metabolic process GO:0046483 290 0.026
positive regulation of nucleoside metabolic process GO:0045979 1 0.026
proteasomal protein catabolic process GO:0010498 2 0.026
regulation of metal ion transport GO:0010959 4 0.026
pronuclear migration GO:0035046 1 0.026
regulation of nucleotide catabolic process GO:0030811 2 0.026
negative regulation of kinase activity GO:0033673 4 0.025
establishment of localization GO:0051234 244 0.025
single fertilization GO:0007338 3 0.025
heterocycle biosynthetic process GO:0018130 215 0.025
cellular macromolecule metabolic process GO:0044260 391 0.025
regulation of erk1 and erk2 cascade GO:0070372 4 0.025
chordate embryonic development GO:0043009 271 0.024
germ line stem cell maintenance GO:0030718 2 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
negative regulation of synapse assembly GO:0051964 2 0.024
regulation of nucleoside metabolic process GO:0009118 2 0.024
positive regulation of secretion GO:0051047 1 0.023
nucleic acid metabolic process GO:0090304 244 0.023
positive regulation of secretion by cell GO:1903532 1 0.023
response to uv GO:0009411 3 0.023
compound eye development GO:0048749 2 0.023
cell part morphogenesis GO:0032990 246 0.023
regulation of multicellular organism growth GO:0040014 4 0.023
organic substance transport GO:0071702 58 0.023
regulation of biosynthetic process GO:0009889 250 0.023
regulation of synaptic plasticity GO:0048167 1 0.023
negative regulation of catabolic process GO:0009895 3 0.023
single organism organelle organization GO:1902589 199 0.022
stem cell maintenance GO:0019827 4 0.022
cellular component biogenesis GO:0044085 178 0.022
nuclear migration GO:0007097 3 0.022
regulation of gtp catabolic process GO:0033124 2 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.022
cellular amino acid metabolic process GO:0006520 7 0.022
fertilization GO:0009566 3 0.022
negative regulation of mapk cascade GO:0043409 4 0.022
neuron development GO:0048666 262 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 3 0.022
modification dependent macromolecule catabolic process GO:0043632 3 0.022
cellular component morphogenesis GO:0032989 336 0.021
positive regulation of nucleotide catabolic process GO:0030813 1 0.021
regulation of protein targeting GO:1903533 2 0.021
erk1 and erk2 cascade GO:0070371 4 0.021
pole plasm assembly GO:0007315 4 0.021
regulation of apoptotic process GO:0042981 98 0.021
response to drug GO:0042493 3 0.021
transport GO:0006810 220 0.021
response to organic substance GO:0010033 153 0.021
regulation of response to stimulus GO:0048583 269 0.021
regulation of cellular ketone metabolic process GO:0010565 7 0.021
gland development GO:0048732 143 0.021
autophagy GO:0006914 4 0.021
oocyte anterior posterior axis specification GO:0007314 4 0.021
membrane invagination GO:0010324 1 0.020
ameboidal type cell migration GO:0001667 143 0.020
phagocytosis engulfment GO:0006911 1 0.020
single organism localization GO:1902578 225 0.020
single organism transport GO:0044765 206 0.020
response to external stimulus GO:0009605 264 0.020
gene expression GO:0010467 252 0.020
stem cell proliferation GO:0072089 4 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 3 0.020
regulation of macromolecule biosynthetic process GO:0010556 225 0.020
cellular component assembly GO:0022607 170 0.020
regulation of gtpase activity GO:0043087 2 0.019
actin filament polymerization GO:0030041 2 0.019
endosomal transport GO:0016197 2 0.019
rna metabolic process GO:0016070 219 0.019
organic substance biosynthetic process GO:1901576 289 0.019
regulation of cellular biosynthetic process GO:0031326 245 0.019
mitotic dna integrity checkpoint GO:0044774 4 0.019
meiotic nuclear division GO:0007126 4 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 1 0.019
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 2 0.019
death GO:0016265 121 0.019
macromolecule biosynthetic process GO:0009059 227 0.018
cell morphogenesis involved in differentiation GO:0000904 195 0.018
regulation of protein ubiquitination GO:0031396 3 0.018
embryonic limb morphogenesis GO:0030326 2 0.018
synaptic vesicle transport GO:0048489 1 0.018
regulation of nitrogen compound metabolic process GO:0051171 251 0.018
regulation of meiotic cell cycle GO:0051445 1 0.018
nitrogen compound metabolic process GO:0006807 319 0.018
protein import GO:0017038 3 0.018
blood vessel development GO:0001568 246 0.018
peptidyl serine modification GO:0018209 2 0.018
negative regulation of protein serine threonine kinase activity GO:0071901 2 0.017
neurotransmitter transport GO:0006836 2 0.017
positive regulation of cell adhesion GO:0045785 1 0.017
peptidyl serine phosphorylation GO:0018105 1 0.017
cortical cytoskeleton organization GO:0030865 1 0.017
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 1 0.017
nucleocytoplasmic transport GO:0006913 4 0.017
central nervous system development GO:0007417 387 0.017
establishment of synaptic vesicle localization GO:0097480 1 0.017
ion transport GO:0006811 114 0.017
regulation of cellular protein catabolic process GO:1903362 1 0.017
rna localization GO:0006403 4 0.017
cellular biosynthetic process GO:0044249 286 0.017
nuclear transport GO:0051169 4 0.016
response to chemical GO:0042221 320 0.016
cytoplasm organization GO:0007028 4 0.016
apoptotic process GO:0006915 116 0.016
chemosensory behavior GO:0007635 1 0.016
cell morphogenesis GO:0000902 289 0.016
morphogenesis of an epithelium GO:0002009 333 0.016
positive regulation of dna metabolic process GO:0051054 1 0.016
negative regulation of cellular process GO:0048523 283 0.016
regulation of programmed cell death GO:0043067 101 0.016
positive regulation of gtpase activity GO:0043547 1 0.016
protein complex localization GO:0031503 1 0.016
eye development GO:0001654 277 0.016
protein metabolic process GO:0019538 183 0.015
regulation of circadian rhythm GO:0042752 4 0.015
amide biosynthetic process GO:0043604 1 0.015
negative regulation of protein complex assembly GO:0031333 1 0.015
segmentation GO:0035282 97 0.015
small molecule catabolic process GO:0044282 3 0.015
negative regulation of mitosis GO:0045839 3 0.015
cytoskeleton dependent cytokinesis GO:0061640 3 0.015
regulation of receptor activity GO:0010469 2 0.015
cellular response to external stimulus GO:0071496 2 0.015
regulation of peptidyl tyrosine phosphorylation GO:0050730 1 0.015
spermatid development GO:0007286 2 0.015
negative regulation of protein transport GO:0051224 3 0.015
forebrain regionalization GO:0021871 4 0.015
multicellular organismal response to stress GO:0033555 2 0.015
regulation of cell shape GO:0008360 1 0.015
cell motility GO:0048870 244 0.015
liver development GO:0001889 96 0.015
embryonic organ development GO:0048568 381 0.015
protein targeting to nucleus GO:0044744 3 0.014
single organism biosynthetic process GO:0044711 71 0.014
establishment of protein localization to plasma membrane GO:0090002 1 0.014
cellular component movement GO:0006928 335 0.014
epithelial cell development GO:0002064 42 0.014
biosynthetic process GO:0009058 294 0.014
multi organism process GO:0051704 134 0.014
monoamine transport GO:0015844 1 0.014
regulation of protein binding GO:0043393 3 0.014
medulla oblongata development GO:0021550 4 0.014
regulation of gene expression GO:0010468 265 0.014
regulation of dendrite morphogenesis GO:0048814 3 0.014
protein localization to nucleus GO:0034504 3 0.014
regulation of stem cell differentiation GO:2000736 4 0.014
regulation of localization GO:0032879 104 0.014
regulation of biological quality GO:0065008 263 0.014
protein homooligomerization GO:0051260 3 0.014
atp catabolic process GO:0006200 4 0.014
synaptic vesicle localization GO:0097479 1 0.014
localization of cell GO:0051674 244 0.014
regulation of epithelial cell proliferation GO:0050678 3 0.014
golgi vesicle transport GO:0048193 3 0.014
regulation of exocytosis GO:0017157 1 0.014
positive regulation of cell division GO:0051781 2 0.013
negative regulation of macromolecule metabolic process GO:0010605 76 0.013
cellular response to nutrient levels GO:0031669 2 0.013
regulation of intracellular protein transport GO:0033157 3 0.013
regulation of filopodium assembly GO:0051489 2 0.013
regulation of rna metabolic process GO:0051252 224 0.013
retina development in camera type eye GO:0060041 146 0.013
regulation of wound healing GO:0061041 2 0.013
intracellular mrna localization GO:0008298 1 0.013
regulation of mrna processing GO:0050684 3 0.013
cellular response to extracellular stimulus GO:0031668 2 0.013
regulation of cell death GO:0010941 103 0.013
regulation of fatty acid metabolic process GO:0019217 1 0.013
small gtpase mediated signal transduction GO:0007264 8 0.013
nucleobase containing compound biosynthetic process GO:0034654 205 0.013
cell substrate adhesion GO:0031589 4 0.013
regulation of nucleobase containing compound metabolic process GO:0019219 250 0.013
negative regulation of map kinase activity GO:0043407 2 0.013
regulation of cytokine production GO:0001817 3 0.013
response to glucocorticoid GO:0051384 1 0.013
somitogenesis GO:0001756 87 0.013
mitotic g2 m transition checkpoint GO:0044818 3 0.013
ribonucleotide metabolic process GO:0009259 27 0.013
production of molecular mediator of immune response GO:0002440 2 0.013
negative regulation of chromosome organization GO:2001251 1 0.013
negative regulation of cytoplasmic transport GO:1903650 2 0.013
negative regulation of metabolic process GO:0009892 86 0.013
protein import into nucleus GO:0006606 3 0.013
protein stabilization GO:0050821 2 0.013
negative regulation of cellular metabolic process GO:0031324 77 0.013
response to nutrient GO:0007584 3 0.013
negative regulation of intracellular protein transport GO:0090317 3 0.013
regulation of transmembrane transporter activity GO:0022898 2 0.012
system process GO:0003008 185 0.012
modification dependent protein catabolic process GO:0019941 3 0.012
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 1 0.012
nucleic acid transport GO:0050657 2 0.012
cellular component maintenance GO:0043954 3 0.012
rna 3 end processing GO:0031123 2 0.012
negative regulation of catalytic activity GO:0043086 21 0.012
glucocorticoid metabolic process GO:0008211 2 0.012
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 1 0.012
phosphate containing compound metabolic process GO:0006796 108 0.012
very long chain fatty acid metabolic process GO:0000038 4 0.012
cortical actin cytoskeleton organization GO:0030866 1 0.012
regionalization GO:0003002 274 0.012
nucleoside monophosphate catabolic process GO:0009125 4 0.012
regulation of establishment or maintenance of cell polarity GO:0032878 2 0.012
positive regulation of signaling GO:0023056 56 0.012
brain development GO:0007420 293 0.012
axon development GO:0061564 166 0.012
positive regulation of biological process GO:0048518 253 0.012
double strand break repair GO:0006302 3 0.012
antimicrobial humoral response GO:0019730 2 0.012
keratinocyte differentiation GO:0030216 0 0.012
negative regulation of protein import into nucleus GO:0042308 2 0.012
ribonucleoside monophosphate catabolic process GO:0009158 4 0.012
nucleobase containing compound metabolic process GO:0006139 274 0.012
negative regulation of programmed cell death GO:0043069 58 0.012
monovalent inorganic cation transport GO:0015672 42 0.012
locomotion GO:0040011 313 0.012
regulation of reactive oxygen species metabolic process GO:2000377 2 0.012
angiogenesis GO:0001525 158 0.012
growth GO:0040007 174 0.012
i kappab kinase nf kappab signaling GO:0007249 4 0.011
eye morphogenesis GO:0048592 144 0.011
neuronal action potential GO:0019228 18 0.011
nucleic acid templated transcription GO:0097659 181 0.011
response to vitamin GO:0033273 3 0.011
alcohol biosynthetic process GO:0046165 2 0.011
adherens junction maintenance GO:0034334 2 0.011
neuron differentiation GO:0030182 353 0.011
estrogen metabolic process GO:0008210 2 0.011
developmental programmed cell death GO:0010623 4 0.011
response to biotic stimulus GO:0009607 97 0.011
positive regulation of cellular process GO:0048522 201 0.011
immune system process GO:0002376 241 0.011
phosphatidylinositol mediated signaling GO:0048015 2 0.011
negative regulation of epithelial cell proliferation GO:0050680 1 0.011
cell cycle arrest GO:0007050 1 0.011
negative regulation of myeloid cell differentiation GO:0045638 1 0.011
locomotor rhythm GO:0045475 3 0.011
regulation of cytoplasmic transport GO:1903649 4 0.011
ion transmembrane transport GO:0034220 91 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 4 0.011
primary neural tube formation GO:0014020 1 0.011
secondary metabolic process GO:0019748 3 0.011
establishment of rna localization GO:0051236 3 0.011
carbohydrate biosynthetic process GO:0016051 1 0.011
negative regulation of signal transduction GO:0009968 94 0.011
regulation of protein localization to plasma membrane GO:1903076 1 0.011
peptidyl threonine phosphorylation GO:0018107 1 0.011
multicellular organismal signaling GO:0035637 22 0.011
negative regulation of gene expression GO:0010629 65 0.011
positive regulation of gtp catabolic process GO:0033126 1 0.011
establishment of localization in cell GO:0051649 77 0.011
cellular response to starvation GO:0009267 1 0.011
regulation of lipid transport GO:0032368 4 0.011
cellular respiration GO:0045333 3 0.011
regulation of organ growth GO:0046620 3 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 4 0.011
regulation of dna templated transcription elongation GO:0032784 3 0.011
cellular protein metabolic process GO:0044267 129 0.011
spermatid differentiation GO:0048515 2 0.011
transmission of nerve impulse GO:0019226 19 0.011
cellular response to chemical stimulus GO:0070887 157 0.011
sensory organ development GO:0007423 393 0.011
regulation of intracellular signal transduction GO:1902531 57 0.011
regulation of postsynaptic membrane potential GO:0060078 1 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 2 0.011
regulation of cell substrate adhesion GO:0010810 1 0.011
apoptotic process involved in development GO:1902742 2 0.011
negative regulation of dna replication GO:0008156 2 0.011
negative regulation of nucleocytoplasmic transport GO:0046823 2 0.010
nuclear import GO:0051170 3 0.010
golgi organization GO:0007030 1 0.010
transcription dna templated GO:0006351 181 0.010
positive regulation of ras gtpase activity GO:0032320 1 0.010
regulation of rho protein signal transduction GO:0035023 2 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 2 0.010
cellular macromolecule biosynthetic process GO:0034645 224 0.010
regulation of protein polymerization GO:0032271 2 0.010
long chain fatty acid transport GO:0015909 1 0.010
negative regulation of multi organism process GO:0043901 3 0.010
regulation of production of molecular mediator of immune response GO:0002700 1 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 163 0.010
axonogenesis GO:0007409 152 0.010
single organism membrane organization GO:0044802 20 0.010
hormone secretion GO:0046879 2 0.010
cell migration GO:0016477 237 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 1 0.010
regulation of chromosome segregation GO:0051983 1 0.010
action potential GO:0001508 19 0.010
regulation of cellular response to growth factor stimulus GO:0090287 35 0.010
stem cell division GO:0017145 1 0.010
dna templated transcription elongation GO:0006354 3 0.010

tssc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of cellular proliferation DOID:14566 0 0.019
cancer DOID:162 0 0.019
organ system cancer DOID:0050686 0 0.019
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014