IMP

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Danio rerio

1 genes annotated in zebrafish

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positive regulation of ras gtpase activity

GO:0032320

Any process that activates or increases the activity of a GTPase of the Ras superfamily.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of ras gtpase activity"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of ras gtpase activity" (in gray)

Name	Description	Probability	Func Analog Organism
adrb2a	adrenergic receptor, beta 2a	0.035
mcm6	MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)	0.034
rtcd1	RNA terminal phosphate cyclase domain 1	0.026
cldnc	claudin c	0.026
vdrb	vitamin D receptor b	0.025
zgc:100838	zgc:100838	0.022
sb:cb730	sb:cb730	0.021
cnn2	calponin 2	0.021
rrm2	ribonucleotide reductase M2 polypeptide	0.021
si:ch211-232m7.1	si:ch211-232m7.1	0.021
iqgap1	IQ motif containing GTPase activating protein 1	0.021
gnaia	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a	0.021
abcf2	ATP-binding cassette, sub-family F (GCN20), member 2	0.021
rxrbb	retinoid x receptor, beta b	0.021
tpm4	tropomyosin 4	0.020
zgc:56466	zgc:56466	0.020
ahnak	AHNAK nucleoprotein	0.020
epb4.1l4	erythrocyte protein band 4.1-like 4	0.020
ywhai	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide	0.019
lrrc50	leucine rich repeat containing 50	0.019
sox19a	SRY-box containing gene 19a	0.019
sb:eu854	sb:eu854	0.019
zgc:77517	zgc:77517	0.019
gna12	guanine nucleotide binding protein (G protein) alpha 12	0.018
gstal	glutathione S-transferase, alpha-like	0.018
msna	moesin a	0.018
pacsin3	protein kinase C and casein kinase substrate in neurons 3	0.018
diaph2	diaphanous homolog 2 (Drosophila)	0.017
appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.017
slc43a1a	solute carrier family 43, member 1a	0.017
si:dkey-6n6.4	si:dkey-6n6.4	0.017
tm9sf2	transmembrane 9 superfamily member 2	0.017
gpc4	glypican 4	0.017
ankrd6	ankyrin repeat domain 6	0.017
zgc:110298	zgc:110298	0.016
creld2	cysteine-rich with EGF-like domains 2	0.016
m17	IL-6 subfamily cytokine M17	0.016
stk38l	serine/threonine kinase 38 like	0.016
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.016
foxj1b	forkhead box J1b	0.016
casz1	castor zinc finger 1	0.016
sec24c	SEC24 family, member C (S. cerevisiae)	0.016
arpc5a	actin related protein 2/3 complex, subunit 5A	0.015
kif20bb	kinesin family member 20Bb	0.015
clstn1	calsyntenin 1	0.015
cacnb1	calcium channel, voltage-dependent, beta 1 subunit	0.015
calcrla	calcitonin receptor-like a	0.015
dedd1	death effector domain-containing 1	0.015
ephb4b	eph receptor B4b	0.015
ywhaqb	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b	0.015
depdc1a	DEP domain containing 1a	0.015
rrp12	ribosomal RNA processing 12 homolog (S. cerevisiae)	0.014
appl1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.014
si:dkeyp-117h8.4	si:dkeyp-117h8.4	0.014
gro2	groucho 2	0.014
si:dkey-97i18.2	si:dkey-97i18.2	0.014
ccna2	cyclin A2	0.014
zgc:112329	zgc:112329	0.014
arpc4	actin related protein 2/3 complex, subunit 4	0.014
usp33	ubiquitin specific peptidase 33	0.014
gng12a	guanine nucleotide binding protein (G protein), gamma 12a	0.014
pggt1b	protein geranylgeranyltransferase type I, beta subunit	0.014
bactin1	bactin1	0.014
dmbx1b	diencephalon/mesencephalon homeobox 1b	0.014
mtp	microsomal triglyceride transfer protein	0.014
fyna	FYN oncogene related to SRC, FGR, YES a	0.014
fam76b	family with sequence similarity 76, member B	0.014
tead1a	TEA domain family member 1a	0.014
helt	hey-like transcription factor	0.014
im:7137453	im:7137453	0.014
ap2a1	adaptor-related protein complex 2, alpha 1 subunit	0.014
tp53bp2	tumor protein p53 binding protein, 2	0.014
e4f1	E4F transcription factor 1	0.014
optc	opticin	0.014
admp	anti-dorsalizing morphogenic protein	0.014
gna13b	guanine nucleotide binding protein (G protein), alpha 13b	0.014
LOC569045	novel protein similar to vertebrate WD repeat domain 44 (WDR44)	0.014
lifrb	leukemia inhibitory factor receptor alpha b	0.013
ap3m2	adaptor-related protein complex 3, mu 2 subunit	0.013
mat2a	methionine adenosyltransferase II, alpha	0.013
cyp2p9	cytochrome P450, family 2, subfamily P, polypeptide 9	0.013
rhoaa	ras homolog gene family, member Aa	0.013
tipin	timeless interacting protein	0.013
flt1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.013
hs3st1l2	heparan sulfate (glucosamine) 3-O-sulfotransferase 1-like 2	0.013
plxnb2a	plexin b2a	0.013
zgc:92683	zgc:92683	0.013
dlst	dihydrolipoamide S-succinyltransferase	0.013
whsc1	Wolf-Hirschhorn syndrome candidate 1	0.013
tomm34	translocase of outer mitochondrial membrane 34	0.013
zgc:63587	zgc:63587	0.013
ywhabl	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like	0.013
cd74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.013
angpt1	angiopoietin 1	0.013
med12	mediator of RNA polymerase II transcription, subunit 12 homolog	0.013
nr1h5	nuclear receptor subfamily 1, group H, member 5	0.013
cotl1	coactosin-like 1 (Dictyostelium)	0.013
stmn2b	stathmin-like 2b	0.013
march6	membrane-associated ring finger (C3HC4) 6	0.013
larp6	La ribonucleoprotein domain family, member 6	0.013
s100v2	S100 calcium binding protein V2	0.013
lrrn1	leucine rich repeat neuronal 1	0.013
si:ch211-285f17.1	si:ch211-285f17.1	0.013
ccdc151	coiled-coil domain containing 151	0.013
ckap5	cytoskeleton associated protein 5	0.013
atp1a1b	ATPase, Na+/K+ transporting, alpha 1b polypeptide	0.013
phf21a	PHD finger protein 21A	0.013
otud7b	OTU domain containing 7B	0.013
gltscr1	glioma tumor suppressor candidate region gene 1	0.013
tnikb	TRAF2 and NCK interacting kinase b	0.013
acvr1b	activin A receptor, type IB	0.012
srpr	signal recognition particle receptor (docking protein)	0.012
rap2c	RAP2C, member of RAS oncogene family	0.012
ppm1bb	protein phosphatase, Mg2+/Mn2+ dependent, 1Bb	0.012
chst11	carbohydrate (chondroitin 4) sulfotransferase 11	0.012
sc:d812	sc:d812	0.012
ptprk	protein tyrosine phosphatase, receptor type, K	0.012
rcn1	reticulocalbin 1, EF-hand calcium binding domain	0.012
uba1	ubiquitin-like modifier activating enzyme 1	0.012
acsl4a	acyl-CoA synthetase long-chain family member 4a	0.012
tm9sf4	transmembrane 9 superfamily protein member 4	0.012
ela2	elastase 2	0.012
eif4g2a	eukaryotic translation initiation factor 4, gamma 2a	0.012
si:dkey-199f5.8	si:dkey-199f5.8	0.012
ptrfb	polymerase I and transcript release factor b	0.012
efna1b	ephrin A1b	0.012
si:dkey-24g18.2	si:dkey-24g18.2	0.012
zfand5b	zinc finger, AN1-type domain 5b	0.012
shcbp1	SHC SH2-domain binding protein 1	0.012
hs6st1b	heparan sulfate 6-O-sulfotransferase 1b	0.012
xpo4	exportin 4	0.012
nedd4l	neural precursor cell expressed, developmentally down-regulated 4-like	0.012
clic4	chloride intracellular channel 4	0.012
pif1	PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)	0.012
pik3r3	phosphoinositide-3-kinase, regulatory subunit, polypeptide 3 (p55, gamma)	0.012
yap1	Yes-associated protein 1	0.012
b2m	beta-2-microglobulin	0.012
fbxw11b	F-box and WD-40 domain protein 11b	0.012
rassf2	Ras association (RalGDS/AF-6) domain family member 2	0.012
vasp	vasodilator-stimulated phosphoprotein	0.012
mecr	mitochondrial trans-2-enoyl-CoA reductase	0.012
rab1a	RAB1A, member RAS oncogene family	0.012
zgc:85727	zgc:85727	0.012
zgc:101810	zgc:101810	0.012
ppm1la	protein phosphatase, Mg2+/Mn2+ dependent, 1La	0.012
epha2	eph receptor A2	0.012	Human
galnt14	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)	0.012
rras	related RAS viral (r-ras) oncogene homolog	0.012
zgc:101724	zgc:101724	0.012
clybl	citrate lyase beta-like	0.012
ulk2	unc-51-like kinase 2 (C. elegans)	0.012
arpc5b	actin related protein 2/3 complex, subunit 5B	0.012
eda	ectodysplasin A	0.012
gdi1	GDP dissociation inhibitor 1	0.012	Yeast
si:dkeyp-84f11.5	si:dkeyp-84f11.5	0.012
dpysl5a	dihydropyrimidinase-like 5a	0.012
kif17	kinesin family member 17	0.012
s100s	S100 calcium binding protein S	0.011
zgc:153346	zgc:153346	0.011
atf3	activating transcription factor 3	0.011
cpeb4	cytoplasmic polyadenylation element binding protein 4	0.011
abca5	ATP-binding cassette, sub-family A (ABC1), member 5	0.011
lta4h	leukotriene A4 hydrolase	0.011
irx1b	iroquois homeobox protein 1, b	0.011
phlda2	pleckstrin homology-like domain, family A, member 2	0.011
gipc1	GIPC PDZ domain containing family, member 1	0.011
s100z	S100 calcium binding protein Z	0.011
zgc:55468	zgc:55468	0.011
zgc:77439	zgc:77439	0.011
ndrg3b	N-myc downstream regulated family member 3b	0.011
rwdd3	RWD domain containing 3	0.011
dazap2	DAZ associated protein 2	0.011
amigo1	adhesion molecule with Ig-like domain 1	0.011
ptprea	protein tyrosine phosphatase, receptor type, E, a	0.011
nxn	nucleoredoxin	0.011
alk	anaplastic lymphoma kinase (Ki-1)	0.011
midn	midnolin	0.011
btg3	B-cell translocation gene 3	0.011
zgc:101840	zgc:101840	0.011
im:7141335	im:7141335	0.011
anxa2a	annexin A2a	0.011
ndel1b	nudE nuclear distribution gene E homolog like 1 (A. nidulans) B	0.011	Mouse
tube1	tubulin, epsilon 1	0.011
zgc:174863	zgc:174863	0.011
acad11	acyl-Coenzyme A dehydrogenase family, member 11	0.011
fzd3a	frizzled homolog 3a	0.011
cftr	cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)	0.011
LOC565697	polycystin-1-like	0.011
inhbb	inhibin, beta B	0.011
zbtb4	zinc finger and BTB domain containing 4	0.011
fbxo25	F-box protein 25	0.011
pole2	polymerase (DNA directed), epsilon 2	0.011
slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.011
nin	ninein (GSK3B interacting protein)	0.011
sgpp1	sphingosine-1-phosphate phosphatase 1	0.011
pppde1	PPPDE peptidase domain containing 1	0.011
kcnip1b	Kv channel interacting protein 1 b	0.011
ncor1	nuclear receptor co-repressor 1	0.011
fmnl2a	formin-like 2a	0.011
lgsn	lengsin, lens protein with glutamine synthetase domain	0.011
cltca	clathrin, heavy polypeptide a (Hc)	0.011
si:dkey-42i9.10	si:dkey-42i9.10	0.011
si:dkey-72l14.9	si:dkey-72l14.9	0.011
fnbp1l	formin binding protein 1-like	0.011
lin7a	lin-7 homolog A (C. elegans)	0.011
mecp2	methyl CpG binding protein 2	0.011
zgc:165373	zgc:165373	0.011
akap12b	A kinase (PRKA) anchor protein (gravin) 12b	0.011
agmo	alkylglycerol monooxygenase	0.011
lmf2b	lipase maturation factor 2b	0.011
im:6907928	im:6907928	0.011
mibp	muscle-specific beta 1 integrin binding protein	0.011
chtf18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.011
sb:cb35	sb:cb35	0.011
scinla	scinderin like a	0.011
fbxl4	F-box and leucine-rich repeat protein 4	0.011
prickle2	prickle-like 2 (Drosophila)	0.011
seph	selenoprotein H	0.011
cbln4	cerebellin 4 precursor	0.011
dennd5b	DENN/MADD domain containing 5B	0.011
k23	k23 gene	0.011
lbr	lamin B receptor	0.011
vegfab	vascular endothelial growth factor Ab	0.011
ldb1a	LIM-domain binding factor 1a	0.011
bcl2	B-cell leukemia/lymphoma 2	0.011
zgc:56041	zgc:56041	0.011
slc12a7b	solute carrier family 12, member 7b	0.011
slc39a3	solute carrier family 39 (zinc transporter), member 3	0.011
apex2	APEX nuclease (apurinic/apyrimidinic endonuclease) 2	0.011
lingo1a	leucine rich repeat and Ig domain containing 1a	0.011
zgc:55558	zgc:55558	0.011	Worm
rbp1a	retinol binding protein 1a, cellular	0.011
si:ch211-160j6.2	si:ch211-160j6.2	0.011
smad2	MAD homolog 2 (Drosophila)	0.011
meis2.2	myeloid ecotropic viral integration site 2.2	0.011
hoxc9a	homeo box C9a	0.011
lgi1b	leucine-rich, glioma inactivated 1b	0.011
dusp4	dual specificity phosphatase 4	0.011
egfra	epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)	0.010
LOC564872	monocarboxylate transporter 7-like	0.010
si:ch211-272f3.4	si:ch211-272f3.4	0.010
flrt1b	fibronectin leucine rich transmembrane 1b	0.010
sppl3	signal peptide peptidase 3	0.010
scrn3	secernin 3	0.010
ints9	integrator complex subunit 9	0.010
zgc:63831	zgc:63831	0.010
ndel1a	nudE nuclear distribution gene E homolog like 1 (A. nidulans) A	0.010	Mouse
tssc1	tumor suppressing subtransferable candidate 1	0.010
qtrtd1	queuine tRNA-ribosyltransferase domain containing 1	0.010
ggps1	geranylgeranyl diphosphate synthase 1	0.010
ttc39c	tetratricopeptide repeat domain 39C	0.010
ca16b	carbonic anhydrase XVI b	0.010
slc25a12	solute carrier family 25 (mitochondrial carrier, Aralar), member 12	0.010
icn	ictacalcin	0.010
entpd4	ectonucleoside triphosphate diphosphohydrolase 4	0.010
zgc:64076	zgc:64076	0.010
gria2a	glutamate receptor, ionotropic, AMPA 2a	0.010
camk2g2	calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 2	0.010
mns1	meiosis-specific nuclear structural 1	0.010
slc7a3	solute carrier family 7 (cationic amino acid transporter, y+ system), member 3	0.010
zgc:56409	zgc:56409	0.010
si:dkey-177p2.3	si:dkey-177p2.3	0.010
capza1a	capping protein (actin filament) muscle Z-line, alpha 1a	0.010
otx2	orthodenticle homolog 2	0.010
zgc:112030	zgc:112030	0.010
isoc2	isochorismatase domain containing 2	0.010
nras	neuroblastoma RAS viral (v-ras) oncogene homolog	0.010	Worm
sppl2	signal peptide peptidase-like 2	0.010
zgc:153910	zgc:153910	0.010
si:dkey-21c19.3	si:dkey-21c19.3	0.010
tuba1l2	tubulin, alpha 1, like 2	0.010
si:dkeyp-117b8.1	si:dkeyp-117b8.1	0.010
bzw1b	basic leucine zipper and W2 domains 1b	0.010
wnt11	wingless-type MMTV integration site family, member 11	0.010
si:dkey-236e20.6	si:dkey-236e20.6	0.010
sardh	sarcosine dehydrogenase	0.010
rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.010
pparg	peroxisome proliferator activated receptor gamma	0.010
kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.010	Worm
sgpl1	sphingosine-1-phosphate lyase 1	0.010
furinb	furin (paired basic amino acid cleaving enzyme) b	0.010
podxl	podocalyxin-like	0.010
srrm4	serine/arginine repetitive matrix 4	0.010
im:7138629	im:7138629	0.010
ap3m1	adaptor-related protein complex 3, mu 1 subunit	0.010
im:7142667	im:7142667	0.010
zgc:110201	zgc:110201	0.010
mtdha	metadherin a	0.010
crfb5	cytokine receptor family member b5	0.010
hif1ab	hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b	0.010
LOC555504	novel protocadherin protein	0.010
rab14	RAB14, member RAS oncogene family	0.010
zgc:77415	zgc:77415	0.010
bcl7ba	B-cell CLL/lymphoma 7B, a	0.010
gria4a	glutamate receptor, ionotropic, AMPA 4a	0.010
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.010
hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase	0.010
psme2	proteasome activator subunit 2	0.010
smyd3	SET and MYND domain containing 3	0.010
ppp1r12a	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.010
sb:cb1058	sb:cb1058	0.010
ric8a	resistance to inhibitors of cholinesterase 8 homolog A	0.010
ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.010
dusp14	dual specificity phosphatase 14	0.010
stk25b	serine/threonine kinase 25b	0.010
zgc:158345	zgc:158345	0.010
gna13a	guanine nucleotide binding protein (G protein), alpha 13a	0.010
ispd	isoprenoid synthase domain containing	0.010
hs3st3l	heparan sulfate (glucosamine) 3-O-sulfotransferase 3-like	0.010
ppp2r1b	protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform	0.010
gna11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	0.010
prdm8	PR domain containing 8	0.010
pnx	posterior neuron-specific homeobox	0.010
tekt2	tektin 2 (testicular)	0.010
socs3b	suppressor of cytokine signaling 3b	0.010
cdc42ep1	CDC42 effector protein (Rho GTPase binding) 1	0.010
zgc:101723	zgc:101723	0.010
dlgap1a	discs, large (Drosophila) homolog-associated protein 1a	0.010
zgc:154176	zgc:154176	0.010