IMP
Process View
Homo sapiens
10 genes annotated in human
substance dependence
DOID:9973
A substance-related disorder that involves the continued use of alcohol or other drugs despite despite problems related to use of the substance.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "substance dependence"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| DRD2 | dopamine receptor D2 | 0.937 | ||
| PICK1 | protein interacting with PRKCA 1 | 0.434 | ||
| NSF | N-ethylmaleimide-sensitive factor | 0.319 | ||
| ADH1A | alcohol dehydrogenase 1A (class I), alpha polypeptide | 0.103 | Human | |
| SH3GL3 | SH3-domain GRB2-like 3 | 0.101 | ||
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.066 | ||
| TPPP | tubulin polymerization promoting protein | 0.062 | ||
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | 0.045 | ||
| ADORA2A | adenosine A2a receptor | 0.021 | ||
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.019 | ||
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.017 | ||
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.016 | ||
| ASPA | aspartoacylase | 0.016 | ||
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 | 0.015 | ||
| KCNJ5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.015 | ||
| GLP1R | glucagon-like peptide 1 receptor | 0.014 | ||
| SLC5A5 | solute carrier family 5 (sodium iodide symporter), member 5 | 0.014 | ||
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.012 | ||
| COL20A1 | collagen, type XX, alpha 1 | 0.012 | ||
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | 0.011 | ||
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.003 | ||
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 | 0.003 | ||
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A | 0.003 | ||
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 | 0.002 | ||
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | 0.002 | ||
| CHRNA4 | cholinergic receptor, nicotinic, alpha 4 | 0.001 | ||
| TAS2R16 | taste receptor, type 2, member 16 | 0.001 | ||
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | 0.001 |