IMP

Process View

Homo sapiens

2 genes annotated in human

negative regulation of cholesterol efflux

Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cholesterol efflux"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of cholesterol efflux" (in gray)

Name	Description	Probability
IRAK2	interleukin-1 receptor-associated kinase 2	0.494
PELI3	pellino homolog 3 (Drosophila)	0.460
TRAF6	TNF receptor-associated factor 6	0.233
MYD88	myeloid differentiation primary response gene (88)	0.205
HP	haptoglobin	0.078
MED15	mediator complex subunit 15	0.071
APOC1	apolipoprotein C-I	0.037
IRAK4	interleukin-1 receptor-associated kinase 4	0.030
IRAK3	interleukin-1 receptor-associated kinase 3	0.024
A2M	alpha-2-macroglobulin	0.023
INSIG1	insulin induced gene 1	0.019
LSS	lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)	0.013
SC4MOL	sterol-C4-methyl oxidase-like	0.012
LCAT	lecithin-cholesterol acyltransferase	0.011
IRF7	interferon regulatory factor 7	0.011