Process View
The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida surrounding the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the egg.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "acrosome reaction"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.629 | ||
| GOLM1 | golgi membrane protein 1 | 0.099 | ||
| MAPK15 | mitogen-activated protein kinase 15 | 0.094 | ||
| HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C | 0.046 | ||
| IPO11 | importin 11 | 0.045 | ||
| OPRK1 | opioid receptor, kappa 1 | 0.037 | ||
| CAMKV | CaM kinase-like vesicle-associated | 0.036 | ||
| UGT2B7 | UDP glucuronosyltransferase 2 family, polypeptide B7 | 0.031 | ||
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.031 | ||
| NINL | ninein-like | 0.030 | ||
| CRHR1 | corticotropin releasing hormone receptor 1 | 0.026 | ||
| STX1A | syntaxin 1A (brain) | 0.021 | ||
| ACCN1 | amiloride-sensitive cation channel 1, neuronal | 0.020 | ||
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.020 | ||
| SYN2 | synapsin II | 0.020 | ||
| SV2C | synaptic vesicle glycoprotein 2C | 0.020 | ||
| NRXN1 | neurexin 1 | 0.019 | ||
| GLRA2 | glycine receptor, alpha 2 | 0.019 | Human | |
| SLC17A6 | solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 | 0.019 | ||
| GABRA3 | gamma-aminobutyric acid (GABA) A receptor, alpha 3 | 0.018 | Human | |
| GRIK1 | glutamate receptor, ionotropic, kainate 1 | 0.016 | ||
| NEUROD2 | neurogenic differentiation 2 | 0.016 | ||
| NPY | neuropeptide Y | 0.016 | ||
| FSTL4 | follistatin-like 4 | 0.015 | ||
| KCNQ3 | potassium voltage-gated channel, KQT-like subfamily, member 3 | 0.015 | ||
| PRKCG | protein kinase C, gamma | 0.015 | ||
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 0.014 | Human | |
| KCNJ3 | potassium inwardly-rectifying channel, subfamily J, member 3 | 0.014 | ||
| GPC5 | glypican 5 | 0.014 | ||
| SSTR2 | somatostatin receptor 2 | 0.014 | ||
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.013 | ||
| SLC1A6 | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 | 0.013 | ||
| ELAVL2 | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B) | 0.013 | ||
| GRIA1 | glutamate receptor, ionotropic, AMPA 1 | 0.013 | ||
| KCNQ2 | potassium voltage-gated channel, KQT-like subfamily, member 2 | 0.013 | ||
| ADCYAP1 | adenylate cyclase activating polypeptide 1 (pituitary) | 0.013 | ||
| BSN | bassoon (presynaptic cytomatrix protein) | 0.013 | ||
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 | 0.013 | ||
| SYT7 | synaptotagmin VII | 0.012 | Human | |
| CBLN1 | cerebellin 1 precursor | 0.012 | ||
| USH1C | Usher syndrome 1C (autosomal recessive, severe) | 0.012 | ||
| DAB1 | disabled homolog 1 (Drosophila) | 0.012 | ||
| INA | internexin neuronal intermediate filament protein, alpha | 0.012 | ||
| WSCD2 | WSC domain containing 2 | 0.012 | ||
| EGR4 | early growth response 4 | 0.011 | ||
| STON2 | stonin 2 | 0.011 | ||
| SCN2A | sodium channel, voltage-gated, type II, alpha subunit | 0.011 | ||
| KIAA1045 | KIAA1045 | 0.011 | ||
| CALB1 | calbindin 1, 28kDa | 0.011 | ||
| SLITRK3 | SLIT and NTRK-like family, member 3 | 0.010 | ||
| HCRTR1 | hypocretin (orexin) receptor 1 | 0.010 | ||
| JPH3 | junctophilin 3 | 0.010 | ||
| GABRA5 | gamma-aminobutyric acid (GABA) A receptor, alpha 5 | 0.010 | Human | |
| SNCB | synuclein, beta | 0.010 |