IMP

Process View

Mus musculus

2 genes annotated in mouse

complement activation classical pathway

Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "complement activation classical pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "complement activation classical pathway" (in gray)

Name	Description	Probability	Func Analog Organism
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.861
C1qc	complement component 1, q subcomponent, C chain	0.784	Zebrafish Mouse
Tyrobp	TYRO protein tyrosine kinase binding protein	0.083
Ly86	lymphocyte antigen 86	0.041
C1qb	complement component 1, q subcomponent, beta polypeptide	0.039	Zebrafish Mouse
Ctss	cathepsin S	0.037
Csf1r	colony stimulating factor 1 receptor	0.025
Aif1	allograft inflammatory factor 1	0.024
Lyz2	lysozyme 2	0.017
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.016
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.015
Mrc1	mannose receptor, C type 1	0.011
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.010