IMP

Process View

Mus musculus

2 genes annotated in mouse

negative regulation of translation involved in gene silencing by mirna

The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of translation involved in gene silencing by mirna"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of translation involved in gene silencing by mirna" (in gray)

Name	Description	Probability	Func Analog Organism
Tnrc6b	trinucleotide repeat containing 6b	0.088
Eif2c1	eukaryotic translation initiation factor 2C, 1	0.049	Human
Trim32	tripartite motif-containing 32	0.047	Mouse
Fos	FBJ osteosarcoma oncogene	0.039
Ddx6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	0.030
Junb	Jun-B oncogene	0.027
Btg1	B-cell translocation gene 1, anti-proliferative	0.024
Dusp1	dual specificity phosphatase 1	0.022
Btg2	B-cell translocation gene 2, anti-proliferative	0.014
Jun	Jun oncogene	0.012