IMP
Process View
natural killer cell mediated cytotoxicity
The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "natural killer cell mediated cytotoxicity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| RT1-EC2 | RT1 class Ib, locus EC2 | 0.945 | ||
| Psmb9 | proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2) | 0.891 | ||
| Tap2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.149 | ||
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.084 | Rat | |
| Gzmk | granzyme K | 0.068 | ||
| Prf1 | perforin 1 (pore forming protein) | 0.065 | ||
| Tap1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.058 | ||
| Spn | sialophorin | 0.054 | ||
| Gzmb | granzyme B | 0.053 | ||
| Cd2 | Cd2 molecule | 0.052 | ||
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.052 | ||
| Nkg7 | natural killer cell group 7 sequence | 0.049 | ||
| RT1-CE12 | RT1 class I, locus CE12 | 0.042 | ||
| Mmp12 | matrix metallopeptidase 12 | 0.037 | ||
| Cd8a | CD8a molecule | 0.035 | ||
| Sell | selectin L | 0.031 | ||
| Rt1.aa | MHC class I RT1.Aa alpha-chain | 0.027 | ||
| Xcl1 | chemokine (C motif) ligand 1 | 0.026 | ||
| St8sia4 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 | 0.024 | ||
| Mcpt8 | mast cell protease 8 | 0.024 | ||
| Irf1 | interferon regulatory factor 1 | 0.023 | ||
| Ccl5 | chemokine (C-C motif) ligand 5 | 0.022 | ||
| Fgr | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.017 | ||
| Kmo | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.016 | ||
| Gimap6 | GTPase, IMAP family member 6 | 0.016 | Rat | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.015 | ||
| Cd86 | CD86 molecule | 0.015 | ||
| Il2rb | interleukin 2 receptor, beta | 0.014 | ||
| Plcg2 | phospholipase C, gamma 2 | 0.014 | ||
| Klra17 | killer cell lectin-like receptor, subfamily A, member 17 | 0.014 | ||
| Oas1a | 2'-5' oligoadenylate synthetase 1A | 0.013 | ||
| Fcgr3a | Fc fragment of IgG, low affinity IIIa, receptor | 0.012 | ||
| RT1-N3 | RT1 class Ib, locus N3 | 0.012 | Rat | |
| Gimap4 | GTPase, IMAP family member 4 | 0.011 | ||
| Cxcl10 | chemokine (C-X-C motif) ligand 10 | 0.011 | ||
| Apol3 | apolipoprotein L, 3 | 0.011 | ||
| Cd247 | Cd247 molecule | 0.011 |