Process View
The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "peptidyl diphthamide biosynthetic process from peptidyl histidine"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| DPH2 | Dph2p | 0.608 | ||
| DPH1 | Dph1p | 0.287 | ||
| KTI11 | Kti11p | 0.060 | ||
| SIL1 | Sil1p | 0.051 | ||
| MNN1 | Mnn1p | 0.035 | ||
| RCL1 | Rcl1p | 0.034 | ||
| YLR264C-A | hypothetical protein | 0.029 | ||
| SMM1 | Smm1p | 0.028 | ||
| SRD1 | Srd1p | 0.027 | ||
| MER1 | Mer1p | 0.027 | ||
| ARG8 | Arg8p | 0.024 | ||
| CUP1-1 | Cup1-1p | 0.024 | ||
| YAR068W | hypothetical protein | 0.022 | ||
| LEU2 | Leu2p | 0.022 | ||
| YLR042C | hypothetical protein | 0.022 | ||
| YLR162W | hypothetical protein | 0.021 | ||
| YOL038C-A | hypothetical protein | 0.020 | ||
| PRS2 | Prs2p | 0.020 | ||
| URA3 | Ura3p | 0.020 | ||
| ARP10 | Arp10p | 0.020 | ||
| TAD2 | Tad2p | 0.019 | ||
| HXT3 | Hxt3p | 0.018 | ||
| YPL068C | hypothetical protein | 0.017 | ||
| YPR157W | hypothetical protein | 0.017 | ||
| YIR035C | hypothetical protein | 0.017 | ||
| YAR066W | hypothetical protein | 0.017 | ||
| TCA17 | Tca17p | 0.016 | ||
| GYL1 | Gyl1p | 0.016 | ||
| AQY2 | Aqy2p | 0.016 | ||
| YJL181W | hypothetical protein | 0.016 | ||
| ATP6 | Atp6p | 0.016 | ||
| MF(ALPHA)2 | Mf(alpha)2p | 0.015 | ||
| HO | Hop | 0.015 | ||
| SPL2 | Spl2p | 0.015 | ||
| AUA1 | Aua1p | 0.015 | ||
| YLR419W | hypothetical protein | 0.015 | ||
| YLR040C | hypothetical protein | 0.014 | ||
| ZPS1 | Zps1p | 0.014 | ||
| YOL013W-A | hypothetical protein | 0.014 | ||
| FMT1 | Fmt1p | 0.014 | ||
| HPF1 | Hpf1p | 0.014 | ||
| SCM4 | Scm4p | 0.013 | ||
| YBR013C | hypothetical protein | 0.013 | ||
| ATO3 | Ato3p | 0.013 | ||
| YLR363W-A | hypothetical protein | 0.012 | ||
| AQR1 | Aqr1p | 0.012 | ||
| YLR126C | hypothetical protein | 0.012 | ||
| FUI1 | Fui1p | 0.012 | ||
| MET8 | Met8p | 0.012 | ||
| YLL053C | hypothetical protein | 0.012 | ||
| KAP104 | Kap104p | 0.012 | ||
| ALT2 | Alt2p | 0.012 | ||
| SWC7 | Swc7p | 0.011 | ||
| BIO2 | Bio2p | 0.011 | ||
| YHB1 | Yhb1p | 0.011 | ||
| YAL037C-A | hypothetical protein | 0.011 | ||
| YPR096C | hypothetical protein | 0.011 | ||
| YAL064W | hypothetical protein | 0.011 | ||
| RRT5 | Rrt5p | 0.011 | ||
| PTR2 | Ptr2p | 0.011 | ||
| DPH5 | Dph5p | 0.011 | ||
| YGR283C | hypothetical protein | 0.011 | ||
| URH1 | Urh1p | 0.011 | ||
| EFM1 | Efm1p | 0.011 | ||
| YPL067C | hypothetical protein | 0.011 | ||
| OPT2 | Opt2p | 0.011 | ||
| HLR1 | Hlr1p | 0.011 | ||
| RNP1 | Rnp1p | 0.011 | ||
| YKR075C | hypothetical protein | 0.011 | ||
| BSC1 | Bsc1p | 0.011 | ||
| MMP1 | Mmp1p | 0.011 | ||
| COS12 | Cos12p | 0.011 | ||
| YOL014W | hypothetical protein | 0.010 | ||
| ATS1 | Ats1p | 0.010 | ||
| DIC1 | Dic1p | 0.010 | ||
| TYE7 | Tye7p | 0.010 | ||
| CPD1 | Cpd1p | 0.010 | ||
| YNL067W-B | hypothetical protein | 0.010 | ||
| YGL006W-A | hypothetical protein | 0.010 | ||
| NRG2 | Nrg2p | 0.010 | ||
| INM1 | Inm1p | 0.010 |