The network for 'toxin catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

Drosophila melanogaster
Name Description Probability Func Analog Organism
Ugt35a UDP-glycosyltransferase 35a 0.990
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.990
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.990
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.956
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.926
Cyp6a9 Cytochrome P450-6a9 0.908
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.772
CG12672 CG12672 gene product from transcript CG12672-RA 0.736
JhI-26 Juvenile hormone-inducible protein 26 0.723
Cyp9b2 Cytochrome P450-9b2 0.638
Cyp4p1 Cytochrome P450-4p1 0.576
Cyp6a13 CG2397 gene product from transcript CG2397-RA 0.462
CG6830 CG6830 gene product from transcript CG6830-RA 0.389
CG1927 CG1927 gene product from transcript CG1927-RA 0.370
Osi6 Osiris 6 0.272
Ilp4 Insulin-like peptide 4 0.255
CG10562 CG10562 gene product from transcript CG10562-RA 0.253
CG6834 CG6834 gene product from transcript CG6834-RA 0.252
CG10550 CG10550 gene product from transcript CG10550-RB 0.232
CG4630 CG4630 gene product from transcript CG4630-RA 0.220
CG10560 CG10560 gene product from transcript CG10560-RA 0.217
Cyp6a2 Cytochrome P450-6a2 0.187
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.187
Met Methoprene-tolerant 0.185
CG14935 CG14935 gene product from transcript CG14935-RA 0.178
TotA Turandot A 0.177
Ugt86Da CG18578 gene product from transcript CG18578-RA 0.153
Epac CG34392 gene product from transcript CG34392-RC 0.145
Est-Q Esterase Q 0.145
CG15784 CG15784 gene product from transcript CG15784-RA 0.125
Ugt36Bc CG17932 gene product from transcript CG17932-RB 0.122
Cyp12d1-p CG30489 gene product from transcript CG30489-RA 0.122
Tsp29Fb Tetraspanin 29Fb 0.117
CG4911 CG4911 gene product from transcript CG4911-RA 0.109
Cyp6a8 Cytochrome P450-6a8 0.106
CG6045 CG6045 gene product from transcript CG6045-RA 0.106
nAcRalpha-96Aa nicotinic Acetylcholine Receptor alpha 96Aa 0.105
CG3714 CG3714 gene product from transcript CG3714-RC 0.104
Ilp2 Insulin-like peptide 2 0.103
alpha-Est7 alpha-Esterase-7 0.103
Ugt86Dd CG6633 gene product from transcript CG6633-RB 0.100
Cyp4ac3 CG14031 gene product from transcript CG14031-RA 0.098
NAAT1 Nutrient Amino Acid Transporter 1 0.090
Cyp6a22 CG10240 gene product from transcript CG10240-RA 0.090
CG3759 CG3759 gene product from transcript CG3759-RB 0.088
dib disembodied 0.088
LvpD Larval visceral protein D 0.087
CG6908 CG6908 gene product from transcript CG6908-RA 0.087
CG33307 CG33307 gene product from transcript CG33307-RA 0.085
CG11967 CG11967 gene product from transcript CG11967-RA 0.085
Cyp6d4 CG12800 gene product from transcript CG12800-RA 0.083
Cyp9b1 Cytochrome P450-9b1 0.082
Cyp12d1-d CG33503 gene product from transcript CG33503-RA 0.081
Cyp28d1 CG10833 gene product from transcript CG10833-RA 0.077
CG14528 CG14528 gene product from transcript CG14528-RA 0.075
Adgf-D Adenosine deaminase-related growth factor D 0.072
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.071
CG16898 CG16898 gene product from transcript CG16898-RA 0.071
CG3091 CG3091 gene product from transcript CG3091-RA 0.069
CG17739 CG17739 gene product from transcript CG17739-RA 0.068
CG11426 CG11426 gene product from transcript CG11426-RA 0.067
Jheh3 Juvenile hormone epoxide hydrolase 3 0.065
Crz Corazonin 0.065
Cyp4e2 Cytochrome P450-4e2 0.064
Cyp6a20 CG10245 gene product from transcript CG10245-RB 0.064
Acox57D-p acyl-Coenzyme A oxidase at 57D proximal 0.063
CG9512 CG9512 gene product from transcript CG9512-RA 0.057
CG1774 CG1774 gene product from transcript CG1774-RA 0.057
Fmo-1 Flavin-containing monooxygenase 1 0.054
Cyp28a5 CG8864 gene product from transcript CG8864-RA 0.053
CG16965 CG16965 gene product from transcript CG16965-RB 0.052
CG15408 CG15408 gene product from transcript CG15408-RA 0.052
CG5819 CG5819 gene product from transcript CG5819-RA 0.052
Prat2 Phosphoribosylamidotransferase 2 0.048
CG7017 CG7017 gene product from transcript CG7017-RA 0.047
CG17322 CG17322 gene product from transcript CG17322-RB 0.045
NTPase CG3059 gene product from transcript CG3059-RD 0.043
CG32687 CG32687 gene product from transcript CG32687-RA 0.042
GlcT-1 CG6437 gene product from transcript CG6437-RA 0.042
Cyp6g1 CG8453 gene product from transcript CG8453-RA 0.041
Cyp9h1 CG17577 gene product from transcript CG17577-RA 0.041
Cyp6a17 CG10241 gene product from transcript CG10241-RA 0.041
CG3308 CG3308 gene product from transcript CG3308-RA 0.040
CG5577 CG5577 gene product from transcript CG5577-RA 0.039
CG2064 CG2064 gene product from transcript CG2064-RA 0.038
CG30494 CG30494 gene product from transcript CG30494-RA 0.038
CG6656 CG6656 gene product from transcript CG6656-RA 0.038
Doc3 Dorsocross3 0.037
CG31974 CG31974 gene product from transcript CG31974-RB 0.036
GstE5 Glutathione S transferase E5 0.036
NPFR1 neuropeptide F receptor 0.036
CG8679 CG8679 gene product from transcript CG8679-RA 0.036
alpha-Est1 alpha-Esterase-1 0.035
CG32695 CG32695 gene product from transcript CG32695-RA 0.034
CG11893 CG11893 gene product from transcript CG11893-RA 0.034
CG11841 CG11841 gene product from transcript CG11841-RA 0.033
Rcd2 Reduction in Cnn dots 2 0.032
CG6283 CG6283 gene product from transcript CG6283-RA 0.032
CG5778 CG5778 gene product from transcript CG5778-RB 0.032
Cyp6g2 CG8859 gene product from transcript CG8859-RA 0.032
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.997
Otc ornithine transcarbamylase 0.997
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.987
Sult1d1 sulfotransferase family 1D, member 1 0.946
Cyp2c50 cytochrome P450, family 2, subfamily c, polypeptide 50 0.934
Gstm1 glutathione S-transferase, mu 1 0.875
Ces1d carboxylesterase 1D 0.817
Cps1 carbamoyl-phosphate synthetase 1 0.757
Gsta2 glutathione S-transferase, alpha 2 (Yc2) 0.743
Fmo5 flavin containing monooxygenase 5 0.665
Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 0.656
Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 0.640
Sult1b1 sulfotransferase family 1B, member 1 0.629
Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 0.600
Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.570
Crp C-reactive protein, pentraxin-related 0.525
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.517
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.507
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.506
Cd180 CD180 antigen 0.491
Fabp1 fatty acid binding protein 1, liver 0.448
Cyp3a41b cytochrome P450, family 3, subfamily a, polypeptide 41B 0.376
Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 0.362
Gsta3 glutathione S-transferase, alpha 3 0.354
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.348
Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 0.315
Gstm3 glutathione S-transferase, mu 3 0.303
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.300
Gstt1 glutathione S-transferase, theta 1 0.277
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.272
Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 0.263
Ces1g carboxylesterase 1G 0.261
F9 coagulation factor IX 0.235
Tdo2 tryptophan 2,3-dioxygenase 0.234
Pgls 6-phosphogluconolactonase 0.230
Abcc2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 0.221
Akr1c6 aldo-keto reductase family 1, member C6 0.215
Alb albumin 0.213
Rdh7 retinol dehydrogenase 7 0.208
Msr1 macrophage scavenger receptor 1 0.192
Adh1 alcohol dehydrogenase 1 (class I) 0.190
Ces2g carboxylesterase 2G 0.171
Cfhr1 complement factor H-related 1 0.157
Gstm6 glutathione S-transferase, mu 6 0.153
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.143
Tmem30b transmembrane protein 30B 0.137
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.134
Inmt indolethylamine N-methyltransferase 0.125
Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 0.123
Fmo1 flavin containing monooxygenase 1 0.116
Mup19 major urinary protein 19 0.115
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.110
Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 0.109
Mug2 murinoglobulin 2 0.107
Aass aminoadipate-semialdehyde synthase 0.102
Bhmt betaine-homocysteine methyltransferase 0.099
Tmem59 transmembrane protein 59 0.097
Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 0.093
Bche butyrylcholinesterase 0.089
Aif1 allograft inflammatory factor 1 0.085
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.083
Iyd iodotyrosine deiodinase 0.081
F13b coagulation factor XIII, beta subunit 0.081
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.081
Rbp4 retinol binding protein 4, plasma 0.077
Fga fibrinogen alpha chain 0.077
Pon1 paraoxonase 1 0.069
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.067
Clec4b1 C-type lectin domain family 4, member b1 0.065
Cfhr2 complement factor H-related 2 0.060
Ncf1 neutrophil cytosolic factor 1 0.059
Vmn1r45 vomeronasal 1 receptor 45 0.058
Aadac arylacetamide deacetylase (esterase) 0.056
Rgn regucalcin 0.056
Lair1 leukocyte-associated Ig-like receptor 1 0.055
Cyp4a31 cytochrome P450, family 4, subfamily a, polypeptide 31 0.055
Vsig4 V-set and immunoglobulin domain containing 4 0.052
Serpina1a serine (or cysteine) peptidase inhibitor, clade A, member 1A 0.052
Tmem205 transmembrane protein 205 0.051
Cbr1 carbonyl reductase 1 0.051
Gm3776 predicted gene 3776 0.051
Baat bile acid-Coenzyme A: amino acid N-acyltransferase 0.050
Defb1 defensin beta 1 0.048
Cyp2c55 cytochrome P450, family 2, subfamily c, polypeptide 55 0.047
Ear2 eosinophil-associated, ribonuclease A family, member 2 0.047
Kynu kynureninase (L-kynurenine hydrolase) 0.046
Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 0.046
Aldob aldolase B, fructose-bisphosphate 0.044
Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 0.042
Cd33 CD33 antigen 0.042
AA672641 expressed sequence AA672641 0.040
Slco1b2 solute carrier organic anion transporter family, member 1b2 0.040
Lcp2 lymphocyte cytosolic protein 2 0.039
Klra2 killer cell lectin-like receptor, subfamily A, member 2 0.039
C730048C13Rik RIKEN cDNA C730048C13 gene 0.038
Cyb5 cytochrome b-5 0.038
Gm4788 predicted gene 4788 0.038
Frk fyn-related kinase 0.038
G6pc glucose-6-phosphatase, catalytic 0.037
Slc11a1 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 0.036
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.691
LOC293989 cytochrome P450-like 0.385
Mgst1 microsomal glutathione S-transferase 1 0.315
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.268
Ephx1 epoxide hydrolase 1, microsomal 0.263
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.237
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.223
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.149
Gstm1 glutathione S-transferase mu 1 0.146
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.129
Ddt D-dopachrome tautomerase 0.119
Dao D-amino-acid oxidase 0.117
Mgst2 microsomal glutathione S-transferase 2 0.113
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.112
Cyp3a23/3a1 cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 1 0.103
Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 0.102
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.101
Gsta5 glutathione S-transferase Yc2 subunit 0.099
Gna15 guanine nucleotide binding protein, alpha 15 0.096
Gamt guanidinoacetate N-methyltransferase 0.094
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.092
Tst thiosulfate sulfurtransferase 0.087
Otc ornithine carbamoyltransferase 0.085
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.085
Slco1a1 solute carrier organic anion transporter family, member 1a1 0.075
Gstp1 glutathione S-transferase pi 1 0.072
Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 0.071
Tmem205 transmembrane protein 205 0.070
Cyp2a2 cytochrome P450, family 2, subfamily a, polypeptide 2 0.067
Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 0.063
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.060
Cyp2c13 cytochrome P450, family 2, subfamily c, polypeptide 13 0.059
Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 0.058
Mosc2 MOCO sulphurase C-terminal domain containing 2 0.056
Akr1c12 aldo-keto reductase family 1, member C12 0.049
Acy1 aminoacylase 1 0.048
Slco1a4 solute carrier organic anion transporter family, member 1a4 0.046
Il1a interleukin 1 alpha 0.042
LOC100363376 rCG51296-like 0.042
Apob apolipoprotein B 0.041
Sult1c3 sulfotransferase family, cytosolic, 1C, member 3 0.041
Ces1c carboxylesterase 1C 0.040
Sgk2 serum/glucocorticoid regulated kinase 2 0.038
Gsta2 glutathione S-transferase A2 0.036
Gsta4 glutathione S-transferase alpha 4 0.036
Aqp9 aquaporin 9 0.033
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.031
Sult2al1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring-like 1 0.030
Abhd14b abhydrolase domain containing 14b 0.029
Slco1b3 solute carrier organic anion transporter family, member 1b3 0.028
Ccl4 chemokine (C-C motif) ligand 4 0.028
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 0.027
Acot12 acyl-CoA thioesterase 12 0.027
A1i3 alpha-1-inhibitor III 0.027
Neurl3 neuralized homolog 3 (Drosophila) 0.026
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.026
Rup2 urinary protein 2 0.025
Igsf6 immunoglobulin superfamily, member 6 0.025
Cyp2c22 cytochrome P450, family 2, subfamily c, polypeptide 22 0.023
Mettl7b methyltransferase like 7B 0.023
Gstt3 glutathione S-transferase, theta 3 0.021
Slc22a18 solute carrier family 22, member 18 0.021
Ces1f carboxylesterase 1F 0.021
Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 0.020
Akr1d1 aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) 0.020
Dmgdh dimethylglycine dehydrogenase 0.019
Gjb1 gap junction protein, beta 1 0.019
Alad aminolevulinate, delta-, dehydratase 0.019
Hnf1a HNF1 homeobox A 0.019
Fut9 fucosyltransferase 9 (alpha (1,3) fucosyltransferase) 0.018
Olr1701 olfactory receptor 1701 0.018
Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.018
Cela1 chymotrypsin-like elastase family, member 1 0.018
Gstm2 glutathione S-transferase mu 2 0.018
Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.017
Ust5r integral membrane transport protein UST5r 0.017
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.017
Il1b interleukin 1 beta 0.017
Spink1 serine peptidase inhibitor, Kazal type 1 0.016
Pttg1 pituitary tumor-transforming 1 0.016
Cyb5a cytochrome b5 type A (microsomal) 0.016
Slc22a7 solute carrier family 22 (organic anion transporter), member 7 0.016
Nqo1 NAD(P)H dehydrogenase, quinone 1 0.016
Tmem53 transmembrane protein 53 0.016
Cd46 CD46 molecule, complement regulatory protein 0.016
Cyp2c12 cytochrome P450, family 2, subfamily c, polypeptide 12 0.015
Abcc6 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 0.015
Dak dihydroxyacetone kinase 2 homolog (S. cerevisiae) 0.015
Hrsp12 heat-responsive protein 12 0.015
Gckr glucokinase (hexokinase 4) regulator 0.015
Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 0.014
Akr7a3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) 0.014
Hao2 hydroxyacid oxidase 2 (long chain) 0.014
Pir pirin (iron-binding nuclear protein) 0.013
Selenbp1 selenium binding protein 1 0.013
Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 0.012
Akr1c1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.012
Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 0.012
Cyp2j3 cytochrome P450, family 2, subfamily j, polypeptide 3 0.012
Cyp2c7 cytochrome P450, family 2, subfamily c, polypeptide 7 0.012
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
AAD14 Aad14p 0.512
AAD15 Aad15p 0.062
AAD4 Aad4p 0.056
AAD16 Aad16p 0.032
FLO9 Flo9p 0.020
GTT2 Gtt2p 0.017
SRD1 Srd1p 0.017
LEU2 Leu2p 0.016
ARP10 Arp10p 0.015
YLR162W hypothetical protein 0.015
SPL2 Spl2p 0.015
YAR068W hypothetical protein 0.014
MER1 Mer1p 0.014
YPR157W hypothetical protein 0.013
AUA1 Aua1p 0.013
YOL038C-A hypothetical protein 0.013
ARG8 Arg8p 0.013
YLR264C-A hypothetical protein 0.013
YCT1 Yct1p 0.013
YLR042C hypothetical protein 0.013
NCE103 Nce103p 0.012
ZPS1 Zps1p 0.012
CUP1-1 Cup1-1p 0.012
HXT3 Hxt3p 0.012
CPD1 Cpd1p 0.011
YJL206C hypothetical protein 0.011
BAT2 Bat2p 0.011
YAL037C-A hypothetical protein 0.011
YBR013C hypothetical protein 0.011
SRX1 Srx1p 0.011
YMR317W hypothetical protein 0.011
FAA2 Faa2p 0.011
HPF1 Hpf1p 0.010
YAL064W hypothetical protein 0.010
YPL272C hypothetical protein 0.010