The network for 'interleukin 1 beta biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

interleukin 1 beta biosynthetic process

The chemical reactions and pathways resulting in the formation of interleukin-1 beta.

Name Description Probability Func Analog Organism
GNLY granulysin 0.994
PRF1 perforin 1 (pore forming protein) 0.988
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.945
NKG7 natural killer cell group 7 sequence 0.776
GZMK granzyme K (granzyme 3; tryptase II) 0.626
ELANE elastase, neutrophil expressed 0.626
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.539
CST7 cystatin F (leukocystatin) 0.396
IL2RB interleukin 2 receptor, beta 0.376
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.362
CD8A CD8a molecule 0.338
CTSG cathepsin G 0.320
GPR171 G protein-coupled receptor 171 0.234
MPO myeloperoxidase 0.223
CXCR6 chemokine (C-X-C motif) receptor 6 0.212
CD3D CD3d molecule, delta (CD3-TCR complex) 0.201
ITK IL2-inducible T-cell kinase 0.191
IL18RAP interleukin 18 receptor accessory protein 0.190
CAMP cathelicidin antimicrobial peptide 0.176
SRGN serglycin 0.134
TARP TCR gamma alternate reading frame protein 0.126
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.125
CD2 CD2 molecule 0.107
FASLG Fas ligand (TNF superfamily, member 6) 0.087
GZMM granzyme M (lymphocyte met-ase 1) 0.080
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.076
AZU1 azurocidin 1 0.073
PRTN3 proteinase 3 0.063
SH2D1A SH2 domain containing 1A 0.062
CTSW cathepsin W 0.061
IFNG interferon, gamma 0.058
HDC histidine decarboxylase 0.058
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.048
CLEC4G C-type lectin domain family 4, member G 0.046
TRAT1 T cell receptor associated transmembrane adaptor 1 0.046
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.031
RNASE3 ribonuclease, RNase A family, 3 0.030
IGL@ immunoglobulin lambda locus 0.026
GFI1 growth factor independent 1 transcription repressor 0.026
SLAMF7 SLAM family member 7 0.025
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.025
CD160 CD160 molecule 0.022
BPI bactericidal/permeability-increasing protein 0.022
CCL5 chemokine (C-C motif) ligand 5 0.021
CCL4 chemokine (C-C motif) ligand 4 0.020
XCL2 chemokine (C motif) ligand 2 0.020
CLEC3B C-type lectin domain family 3, member B 0.020
CD96 CD96 molecule 0.020
TPSB2 tryptase beta 2 (gene/pseudogene) 0.019
CPA3 carboxypeptidase A3 (mast cell) 0.019
PGLYRP1 peptidoglycan recognition protein 1 0.018
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.018
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.016
CD7 CD7 molecule 0.016
LAG3 lymphocyte-activation gene 3 0.015
CFP complement factor properdin 0.015
DEFA4 defensin, alpha 4, corticostatin 0.015
CD247 CD247 molecule 0.015
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.015
S100A12 S100 calcium binding protein A12 0.014
CLEC10A C-type lectin domain family 10, member A 0.014
CXCR3 chemokine (C-X-C motif) receptor 3 0.014
F13A1 coagulation factor XIII, A1 polypeptide 0.013
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.013
LTF lactotransferrin 0.013
TBX21 T-box 21 0.012
LTC4S leukotriene C4 synthase 0.012
NFE2 nuclear factor (erythroid-derived 2), 45kDa 0.012
CD48 CD48 molecule 0.011
CD52 CD52 molecule 0.011
IGJ immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides 0.011
ASGR2 asialoglycoprotein receptor 2 0.011
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism