IMP
Process View
The network for 'cannabinoid signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cannabinoid signaling pathway
The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| TP63 | tumor protein p63 | 0.372 | |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 | 0.218 | |
| POU2F2 | POU class 2 homeobox 2 | 0.203 | |
| GFRA4 | GDNF family receptor alpha 4 | 0.191 | |
| TSPAN32 | tetraspanin 32 | 0.134 | |
| CD5 | CD5 molecule | 0.105 | |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.093 | |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 | 0.085 | |
| HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.085 | |
| CRHR2 | corticotropin releasing hormone receptor 2 | 0.072 | |
| NEUROD2 | neurogenic differentiation 2 | 0.069 | |
| DENND1C | DENN/MADD domain containing 1C | 0.067 | |
| ACAP1 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 | 0.060 | |
| GMIP | GEM interacting protein | 0.059 | |
| NCR2 | natural cytotoxicity triggering receptor 2 | 0.059 | |
| CD6 | CD6 molecule | 0.058 | |
| LYL1 | lymphoblastic leukemia derived sequence 1 | 0.058 | |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) | 0.055 | |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 | 0.054 | |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 | 0.054 | |
| CTRL | chymotrypsin-like | 0.051 | |
| RGS14 | regulator of G-protein signaling 14 | 0.051 | |
| DRD2 | dopamine receptor D2 | 0.050 | |
| IL19 | interleukin 19 | 0.050 | |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.050 | |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 | 0.048 | |
| MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.044 | |
| PNOC | prepronociceptin | 0.043 | |
| ZNF835 | zinc finger protein 835 | 0.042 | |
| HRH3 | histamine receptor H3 | 0.042 | |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 0.042 | |
| CHIA | chitinase, acidic | 0.042 | |
| GPR12 | G protein-coupled receptor 12 | 0.041 | |
| P2RX1 | purinergic receptor P2X, ligand-gated ion channel, 1 | 0.040 | |
| FOXN1 | forkhead box N1 | 0.039 | |
| GPR97 | G protein-coupled receptor 97 | 0.039 | |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.038 | |
| PDE6G | phosphodiesterase 6G, cGMP-specific, rod, gamma | 0.037 | |
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.036 | |
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.035 | |
| FCHO1 | FCH domain only 1 | 0.035 | |
| OLIG2 | oligodendrocyte lineage transcription factor 2 | 0.033 | |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.032 | |
| GPR15 | G protein-coupled receptor 15 | 0.032 | |
| CD22 | CD22 molecule | 0.031 | |
| C11orf21 | chromosome 11 open reading frame 21 | 0.031 | |
| TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.031 | |
| FLT3 | fms-related tyrosine kinase 3 | 0.031 | |
| AVPR1B | arginine vasopressin receptor 1B | 0.031 | |
| UBASH3A | ubiquitin associated and SH3 domain containing A | 0.030 | |
| ACTL7A | actin-like 7A | 0.030 | |
| KCNA3 | potassium voltage-gated channel, shaker-related subfamily, member 3 | 0.030 | |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide | 0.029 | |
| WNT10B | wingless-type MMTV integration site family, member 10B | 0.028 | |
| CHIT1 | chitinase 1 (chitotriosidase) | 0.028 | |
| EMILIN2 | elastin microfibril interfacer 2 | 0.028 | |
| KRT5 | keratin 5 | 0.027 | |
| SH2D3C | SH2 domain containing 3C | 0.027 | |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 | 0.027 | |
| FGF4 | fibroblast growth factor 4 | 0.027 | |
| PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.025 | |
| SH2D2A | SH2 domain containing 2A | 0.025 | |
| LY9 | lymphocyte antigen 9 | 0.025 | |
| GRAP | GRB2-related adaptor protein | 0.025 | |
| CLC | Charcot-Leyden crystal protein | 0.024 | |
| MLN | motilin | 0.024 | |
| ICOSLG | inducible T-cell co-stimulator ligand | 0.024 | |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 0.023 | |
| SLC7A4 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 4 | 0.023 | |
| B3GNT4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 | 0.023 | |
| HTR1A | 5-hydroxytryptamine (serotonin) receptor 1A | 0.023 | |
| GABRG2 | gamma-aminobutyric acid (GABA) A receptor, gamma 2 | 0.023 | |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 | 0.022 | |
| RAB33A | RAB33A, member RAS oncogene family | 0.022 | |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 | 0.022 | |
| GRM6 | glutamate receptor, metabotropic 6 | 0.022 | |
| GFRA3 | GDNF family receptor alpha 3 | 0.022 | |
| SLC9A3R2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.021 | |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | 0.021 | |
| KRT75 | keratin 75 | 0.021 | |
| SLC22A14 | solute carrier family 22, member 14 | 0.021 | |
| SH2B2 | SH2B adaptor protein 2 | 0.021 | |
| PLA2G2D | phospholipase A2, group IID | 0.021 | |
| EPB42 | erythrocyte membrane protein band 4.2 | 0.021 | |
| CXCR1 | chemokine (C-X-C motif) receptor 1 | 0.020 | |
| GH1 | growth hormone 1 | 0.020 | |
| GRIA4 | glutamate receptor, ionotrophic, AMPA 4 | 0.020 | |
| MC4R | melanocortin 4 receptor | 0.020 | |
| BLK | B lymphoid tyrosine kinase | 0.020 | |
| KIF21B | kinesin family member 21B | 0.020 | |
| TCL1B | T-cell leukemia/lymphoma 1B | 0.020 | |
| KCNA1 | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 0.020 | |
| GH2 | growth hormone 2 | 0.020 | |
| ITGB7 | integrin, beta 7 | 0.019 | |
| ARHGAP4 | Rho GTPase activating protein 4 | 0.019 | |
| MAL | mal, T-cell differentiation protein | 0.019 | |
| CD300C | CD300c molecule | 0.019 | |
| ABLIM3 | actin binding LIM protein family, member 3 | 0.019 | |
| PDZK1 | PDZ domain containing 1 | 0.019 | |
| LDHAL6B | lactate dehydrogenase A-like 6B | 0.019 |
