The network for 'negative regulation of endodeoxyribonuclease activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of endodeoxyribonuclease activity

Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.

Name Description Probability Func Analog Organism
GNLY granulysin 0.996
PRF1 perforin 1 (pore forming protein) 0.988
ITK IL2-inducible T-cell kinase 0.770
NKG7 natural killer cell group 7 sequence 0.671
GZMK granzyme K (granzyme 3; tryptase II) 0.574
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.570
CCL5 chemokine (C-C motif) ligand 5 0.476
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.438
CD3D CD3d molecule, delta (CD3-TCR complex) 0.369
IL2RB interleukin 2 receptor, beta 0.341
CD8A CD8a molecule 0.287
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.278
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.278
CTSW cathepsin W 0.255
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.206
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.191
CXCR6 chemokine (C-X-C motif) receptor 6 0.143
CST7 cystatin F (leukocystatin) 0.128
IL18RAP interleukin 18 receptor accessory protein 0.120
CD2 CD2 molecule 0.113
GPR171 G protein-coupled receptor 171 0.095
TARP TCR gamma alternate reading frame protein 0.067
IFNG interferon, gamma 0.051
CCL4 chemokine (C-C motif) ligand 4 0.040
SLAMF7 SLAM family member 7 0.032
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.030
SH2D1A SH2 domain containing 1A 0.030
CD96 CD96 molecule 0.028
KLRF1 killer cell lectin-like receptor subfamily F, member 1 0.022
FASLG Fas ligand (TNF superfamily, member 6) 0.022
TRAT1 T cell receptor associated transmembrane adaptor 1 0.020
CD160 CD160 molecule 0.019
GZMM granzyme M (lymphocyte met-ase 1) 0.019
PVRIG poliovirus receptor related immunoglobulin domain containing 0.017
HDC histidine decarboxylase 0.015
TBX21 T-box 21 0.014
SRGN serglycin 0.014
ELANE elastase, neutrophil expressed 0.013
CD52 CD52 molecule 0.012
XCL2 chemokine (C motif) ligand 2 0.012
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.012
GPR18 G protein-coupled receptor 18 0.011
CLEC10A C-type lectin domain family 10, member A 0.011
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism