IMP
Process View
The network for 'negative regulation of nuclease activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of nuclease activity
Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| GNLY | granulysin | 0.998 | |
| PRF1 | perforin 1 (pore forming protein) | 0.990 | |
| NKG7 | natural killer cell group 7 sequence | 0.773 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.718 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.490 | |
| CD8A | CD8a molecule | 0.478 | |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.367 | |
| CTSW | cathepsin W | 0.363 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.358 | |
| CST7 | cystatin F (leukocystatin) | 0.329 | |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.199 | |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.195 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.139 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.111 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.105 | |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | 0.102 | |
| IL2RB | interleukin 2 receptor, beta | 0.090 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.085 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.068 | |
| GPR171 | G protein-coupled receptor 171 | 0.063 | |
| ITK | IL2-inducible T-cell kinase | 0.036 | |
| GZMM | granzyme M (lymphocyte met-ase 1) | 0.035 | |
| IFNG | interferon, gamma | 0.035 | |
| SRGN | serglycin | 0.034 | |
| CD160 | CD160 molecule | 0.034 | |
| TRAT1 | T cell receptor associated transmembrane adaptor 1 | 0.031 | |
| PVRIG | poliovirus receptor related immunoglobulin domain containing | 0.030 | |
| CD2 | CD2 molecule | 0.028 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.026 | |
| KLRF1 | killer cell lectin-like receptor subfamily F, member 1 | 0.025 | |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.024 | |
| ELANE | elastase, neutrophil expressed | 0.023 | |
| XCL2 | chemokine (C motif) ligand 2 | 0.021 | |
| IGJ | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 0.020 | |
| SLAMF7 | SLAM family member 7 | 0.020 | |
| IGL@ | immunoglobulin lambda locus | 0.020 | |
| CLEC10A | C-type lectin domain family 10, member A | 0.020 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.019 | |
| TBX21 | T-box 21 | 0.017 | |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.016 | |
| IL18R1 | interleukin 18 receptor 1 | 0.014 | |
| CD96 | CD96 molecule | 0.013 | |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 | 0.013 | |
| GFI1 | growth factor independent 1 transcription repressor | 0.013 | |
| CD3G | CD3g molecule, gamma (CD3-TCR complex) | 0.013 | |
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.013 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.012 | |
| ITGB7 | integrin, beta 7 | 0.012 | |
| CTSG | cathepsin G | 0.011 | |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.011 | |
| LAIR2 | leukocyte-associated immunoglobulin-like receptor 2 | 0.011 | |
| IL10RA | interleukin 10 receptor, alpha | 0.011 |
