IMP
Process View
The network for 'positive regulation of plasminogen activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of plasminogen activation
Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Itih1 | inter-alpha trypsin inhibitor, heavy chain 1 | 0.650 | |
| Cldn3 | claudin 3 | 0.532 | |
| Asgr2 | asialoglycoprotein receptor 2 | 0.487 | |
| Ambp | alpha 1 microglobulin/bikunin | 0.440 | |
| F2 | coagulation factor II | 0.363 | |
| Apoa1 | apolipoprotein A-I | 0.292 | |
| Serpina10 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10 | 0.251 | |
| Cyp2d10 | cytochrome P450, family 2, subfamily d, polypeptide 10 | 0.225 | |
| Plg | plasminogen | 0.170 | |
| Akr1c6 | aldo-keto reductase family 1, member C6 | 0.170 | |
| Pzp | pregnancy zone protein | 0.168 | |
| Hc | hemolytic complement | 0.155 | |
| Ager | advanced glycosylation end product-specific receptor | 0.149 | |
| Prodh2 | proline dehydrogenase (oxidase) 2 | 0.145 | |
| Clic3 | chloride intracellular channel 3 | 0.141 | |
| Ces1c | carboxylesterase 1C | 0.130 | |
| Itih4 | inter alpha-trypsin inhibitor, heavy chain 4 | 0.121 | |
| Lipc | lipase, hepatic | 0.120 | |
| Cpn1 | carboxypeptidase N, polypeptide 1 | 0.112 | |
| Agxt | alanine-glyoxylate aminotransferase | 0.108 | |
| Kng1 | kininogen 1 | 0.100 | |
| Slc27a5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.099 | |
| Mst1 | macrophage stimulating 1 (hepatocyte growth factor-like) | 0.096 | |
| Bik | BCL2-interacting killer | 0.091 | |
| Foxa2 | forkhead box A2 | 0.086 | |
| Cfi | complement component factor i | 0.085 | |
| Fgfr4 | fibroblast growth factor receptor 4 | 0.082 | |
| F13b | coagulation factor XIII, beta subunit | 0.072 | |
| Fxyd1 | FXYD domain-containing ion transport regulator 1 | 0.071 | |
| Serpinc1 | serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 | 0.070 | |
| H1foo | H1 histone family, member O, oocyte-specific | 0.070 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.066 | |
| Tff2 | trefoil factor 2 (spasmolytic protein 1) | 0.065 | |
| Mat1a | methionine adenosyltransferase I, alpha | 0.065 | |
| Apoc4 | apolipoprotein C-IV | 0.061 | |
| Asgr1 | asialoglycoprotein receptor 1 | 0.060 | |
| Igfbp6 | insulin-like growth factor binding protein 6 | 0.059 | |
| Ahsg | alpha-2-HS-glycoprotein | 0.059 | |
| Pcdh12 | protocadherin 12 | 0.057 | |
| Cyp8b1 | cytochrome P450, family 8, subfamily b, polypeptide 1 | 0.053 | |
| Gm6484 | predicted gene 6484 | 0.053 | |
| Tnxb | tenascin XB | 0.052 | |
| Nr1i3 | nuclear receptor subfamily 1, group I, member 3 | 0.052 | |
| Ttc36 | tetratricopeptide repeat domain 36 | 0.052 | |
| Cpn2 | carboxypeptidase N, polypeptide 2 | 0.052 | |
| Proc | protein C | 0.051 | |
| Gc | group specific component | 0.051 | |
| Cyp2c70 | cytochrome P450, family 2, subfamily c, polypeptide 70 | 0.050 | |
| Snx2 | sorting nexin 2 | 0.050 | |
| Slc22a1 | solute carrier family 22 (organic cation transporter), member 1 | 0.049 | |
| F12 | coagulation factor XII (Hageman factor) | 0.045 | |
| Apof | apolipoprotein F | 0.043 | |
| Krt79 | keratin 79 | 0.043 | |
| Apoh | apolipoprotein H | 0.042 | |
| Csrp3 | cysteine and glycine-rich protein 3 | 0.042 | |
| Itih2 | inter-alpha trypsin inhibitor, heavy chain 2 | 0.041 | |
| Inhbe | inhibin beta E | 0.041 | |
| Plunc | palate, lung, and nasal epithelium associated | 0.041 | |
| Apoa5 | apolipoprotein A-V | 0.041 | |
| Afm | afamin | 0.039 | |
| Ern2 | endoplasmic reticulum (ER) to nucleus signalling 2 | 0.036 | |
| Hgd | homogentisate 1, 2-dioxygenase | 0.036 | |
| Hpx | hemopexin | 0.036 | |
| Tekt2 | tektin 2 | 0.035 | |
| U46068 | cDNA sequence U46068 | 0.035 | |
| Serpinf2 | serine (or cysteine) peptidase inhibitor, clade F, member 2 | 0.034 | |
| 1300017J02Rik | RIKEN cDNA 1300017J02 gene | 0.034 | |
| Mfap5 | microfibrillar associated protein 5 | 0.033 | |
| C4bp | complement component 4 binding protein | 0.033 | |
| Nmi | N-myc (and STAT) interactor | 0.033 | |
| Gjb1 | gap junction protein, beta 1 | 0.032 | |
| Fgg | fibrinogen gamma chain | 0.032 | |
| Mt4 | metallothionein 4 | 0.032 | |
| Abcc6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 | 0.032 | |
| Hamp | hepcidin antimicrobial peptide | 0.032 | |
| Wnt5b | wingless-related MMTV integration site 5B | 0.031 | |
| Cldn7 | claudin 7 | 0.031 | |
| Sdsl | serine dehydratase-like | 0.031 | |
| C9 | complement component 9 | 0.030 | |
| Cnn1 | calponin 1 | 0.030 | |
| Apom | apolipoprotein M | 0.030 | |
| Wfdc2 | WAP four-disulfide core domain 2 | 0.030 | |
| Fabp1 | fatty acid binding protein 1, liver | 0.029 | |
| Rdh7 | retinol dehydrogenase 7 | 0.029 | |
| Sycn | syncollin | 0.029 | |
| Fgb | fibrinogen beta chain | 0.028 | |
| Serpina12 | serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 | 0.027 | |
| Proz | protein Z, vitamin K-dependent plasma glycoprotein | 0.027 | |
| Ivl | involucrin | 0.026 | |
| Mug2 | murinoglobulin 2 | 0.026 | |
| Foxa1 | forkhead box A1 | 0.026 | |
| Ccbp2 | chemokine binding protein 2 | 0.026 | |
| Fut2 | fucosyltransferase 2 | 0.026 | |
| AU021092 | expressed sequence AU021092 | 0.026 | |
| Sftpb | surfactant associated protein B | 0.026 | |
| Amdhd1 | amidohydrolase domain containing 1 | 0.025 | |
| Habp2 | hyaluronic acid binding protein 2 | 0.025 | |
| Gja4 | gap junction protein, alpha 4 | 0.025 | |
| Aadat | aminoadipate aminotransferase | 0.025 | |
| Apoa4 | apolipoprotein A-IV | 0.025 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1.000 | |
| PLAUR | plasminogen activator, urokinase receptor | 0.895 | |
| MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.721 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.447 | |
| GAST | gastrin | 0.413 | |
| APOH | apolipoprotein H (beta-2-glycoprotein I) | 0.285 | |
| KNG1 | kininogen 1 | 0.259 | |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.158 | |
| PIGR | polymeric immunoglobulin receptor | 0.110 | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.110 | |
| ORM1 | orosomucoid 1 | 0.083 | |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.081 | |
| WFDC2 | WAP four-disulfide core domain 2 | 0.075 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.070 | |
| TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.069 | |
| FGB | fibrinogen beta chain | 0.069 | |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) | 0.068 | |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 0.062 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.055 | |
| STC1 | stanniocalcin 1 | 0.052 | |
| IL8 | interleukin 8 | 0.050 | |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.050 | |
| GJB1 | gap junction protein, beta 1, 32kDa | 0.050 | |
| SAA4 | serum amyloid A4, constitutive | 0.048 | |
| ECM1 | extracellular matrix protein 1 | 0.047 | |
| C4BPB | complement component 4 binding protein, beta | 0.045 | |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.044 | |
| FOSL1 | FOS-like antigen 1 | 0.043 | |
| LCN2 | lipocalin 2 | 0.043 | |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.042 | |
| PRSS8 | protease, serine, 8 | 0.041 | |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.040 | |
| LAMC3 | laminin, gamma 3 | 0.039 | |
| MUC4 | mucin 4, cell surface associated | 0.039 | |
| TMPRSS11D | transmembrane protease, serine 11D | 0.038 | |
| C8A | complement component 8, alpha polypeptide | 0.036 | |
| TMPRSS2 | transmembrane protease, serine 2 | 0.036 | |
| RAB17 | RAB17, member RAS oncogene family | 0.036 | |
| TFR2 | transferrin receptor 2 | 0.035 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.035 | |
| AMBP | alpha-1-microglobulin/bikunin precursor | 0.034 | |
| CPN1 | carboxypeptidase N, polypeptide 1 | 0.034 | |
| RDH16 | retinol dehydrogenase 16 (all-trans) | 0.033 | |
| FXYD3 | FXYD domain containing ion transport regulator 3 | 0.033 | |
| AMT | aminomethyltransferase | 0.033 | |
| CRP | C-reactive protein, pentraxin-related | 0.032 | |
| HPX | hemopexin | 0.031 | |
| TFF1 | trefoil factor 1 | 0.031 | |
| SERPINA6 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 | 0.031 | |
| S100A2 | S100 calcium binding protein A2 | 0.030 | |
| TFF3 | trefoil factor 3 (intestinal) | 0.030 | |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 0.029 | |
| C8G | complement component 8, gamma polypeptide | 0.029 | |
| F2 | coagulation factor II (thrombin) | 0.029 | |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | 0.029 | |
| XDH | xanthine dehydrogenase | 0.028 | |
| GCGR | glucagon receptor | 0.027 | |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.027 | |
| MTA2 | metastasis associated 1 family, member 2 | 0.027 | |
| SPHK1 | sphingosine kinase 1 | 0.026 | |
| GCKR | glucokinase (hexokinase 4) regulator | 0.026 | |
| CPA3 | carboxypeptidase A3 (mast cell) | 0.025 | |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.025 | |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.025 | |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.025 | |
| PDZK1IP1 | PDZK1 interacting protein 1 | 0.025 | |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.024 | |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 | 0.024 | |
| GPRC5A | G protein-coupled receptor, family C, group 5, member A | 0.024 | |
| GBA3 | glucosidase, beta, acid 3 (cytosolic) | 0.023 | |
| APOB | apolipoprotein B (including Ag(x) antigen) | 0.023 | |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase | 0.023 | |
| THBD | thrombomodulin | 0.023 | |
| LAMB3 | laminin, beta 3 | 0.023 | |
| SPP2 | secreted phosphoprotein 2, 24kDa | 0.022 | |
| C9 | complement component 9 | 0.022 | |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit | 0.022 | |
| CP | ceruloplasmin (ferroxidase) | 0.022 | |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.021 | |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 0.021 | |
| PRSS22 | protease, serine, 22 | 0.021 | |
| TTR | transthyretin | 0.021 | |
| TMPRSS4 | transmembrane protease, serine 4 | 0.020 | |
| VIL1 | villin 1 | 0.020 | |
| ALB | albumin | 0.020 | |
| G0S2 | G0/G1switch 2 | 0.020 | |
| ITIH1 | inter-alpha (globulin) inhibitor H1 | 0.020 | |
| PON3 | paraoxonase 3 | 0.020 | |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.020 | |
| FTCD | formiminotransferase cyclodeaminase | 0.019 | |
| APCS | amyloid P component, serum | 0.019 | |
| LECT2 | leukocyte cell-derived chemotaxin 2 | 0.019 | |
| TNC | tenascin C | 0.019 | |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.019 | |
| C1orf116 | chromosome 1 open reading frame 116 | 0.019 | |
| DMBT1 | deleted in malignant brain tumors 1 | 0.019 | |
| TAT | tyrosine aminotransferase | 0.019 | |
| AFM | afamin | 0.019 | |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) | 0.019 | |
| SLPI | secretory leukocyte peptidase inhibitor | 0.019 |